Cited by 209Vaccine Coverage and HesitancyImmune responses and vaccinationsBacterial Infections and Vaccines

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Immunization: vital progress, unfinished agenda

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Piot, Peter, Larson, Heidi J., O’Brien, Katherine L., N’kengasong, John, Ng, Edmond, Sow, Samba, Kampmann, Beate·2019·Nature

DOI 10.1038/s41586-019-1656-7

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Abstract

Vaccination against infectious diseases has changed the future of the human species, saving millions of lives every year, both children and adults, and providing major benefits to society as a whole. Here we show, however, that national and sub-national coverage of vaccination varies greatly and major unmet needs persist. Although scientific progress opens exciting perspectives in terms of new vaccines, the pathway from discovery to sustainable implementation can be long and difficult, from the financing, development and licensing to programme implementation and public acceptance. Immunization is one of the best investments in health and should remain a priority for research, industry, public health and society.

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Authors: Piot, P., Larson, H. J., O’Brien, K. L., N’kengasong, J., Ng, E., Sow, S., & Kampmann, B.
Affiliations: London School of Hygiene & Tropical Medicine (GB)
University of Antwerp (BE)
World Health Organization (CH)
Centre Pour le Développement des Vaccins-Mali (ML)
ORCID: Larson, Heidi J.
O’Brien, Katherine L.
Ng, Edmond
Sow, Samba
Kampmann, Beate
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 2019-11-06
Volume: 575
Issue: 7781
Pages: 119-129
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/s41586-019-1656-7
OpenAlex: W2985393490
Cited by: 206
References: 72
Citations by year: 2026: 21 · 2025: 23 · 2024: 28 · 2023: 21 · 2022: 45 · 2021: 39 · 2020: 29
FWCI: 6.17
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.springer.com/tdm (tdm)
www.springer.com/tdm (vor)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
RePEc: Research Papers in Economics (submittedVersion)
Funders: Bill and Melinda Gates Foundation
Pfizer
World Health Organization
Wellcome Trust
UK Research and Innovation
National Institute for Health and Care Research (SRF-2009-02-07)
European Commission
Medical Research Council (MR/R005990/1, MC_PC_17221, MR/R005990/2, MC_EX_MR/K011944/1, MC_EX_MR/P024270/1)
Topics: Social Sciences › Health › Vaccine Coverage and Hesitancy
Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
Keywords: immunization, vaccination, vaccination coverage, vaccine development, vaccine implementation, vaccine safety, vaccine financing, vaccine licensure, vaccine hesitancy, infectious disease prevention, public health investment
MeSH terms: Drug Development, Animals, Humans, Mortality, Philippines, Social Change, Vaccination, Vaccines

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Immunization: vital progress, unfinished agenda

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