The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Infection of dogs with SARS-CoV-2
Open accessAbstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan in December 2019 and caused coronavirus disease 2019 (COVID-19)1,2. In 2003, the closely related SARS-CoV had been detected in domestic cats and a dog3. However, little is known about the susceptibility of domestic pet mammals to SARS-CoV-2. Here, using PCR with reverse transcription, serology, sequencing the viral genome and virus isolation, we show that 2 out of 15 dogs from households with confirmed human cases of COVID-19 in Hong Kong were found to be infected with SARS-CoV-2. SARS-CoV-2 RNA was detected in five nasal swabs collected over a 13-day period from a 17-year-old neutered male Pomeranian. A 2.5-year-old male German shepherd was positive for SARS-CoV-2 RNA on two occasions and virus was isolated from nasal and oral swabs. Antibody responses were detected in both dogs using plaque-reduction-neutralization assays. Viral genetic sequences of viruses from the two dogs were identical to the virus detected in the respective human cases. The dogs remained asymptomatic during quarantine. The evidence suggests that these are instances of human-to-animal transmission of SARS-CoV-2. It is unclear whether infected dogs can transmit the virus to other animals or back to humans. Two out of 15 dogs from households with confirmed human cases of COVID-19 were asymptomatically infected with SARS-CoV-2 and showed antibody responses to the virus.
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Wölfel, R., Corman, V. M., Guggemos, W., Seilmaier, M., Zange, S., Müller, M. A., Niemeyer, D., Jones, T. C., Vollmar, P., Rothe, C., et al. (2020) · Nature · doi:10.1038/s41586-020-2196-x · Cited by 6,661
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
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MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea, 2015
Choe, P. G., Perera, R. A. P. M., Park, W. B., Song, K.-H., Bang, J. H., Kim, E. S., Kim, H. B., Ko, L. W. R., Park, S. W., Kim, N.-J., et al. (2017) · Emerging Infectious Diseases · doi:10.3201/eid2307.170310 · Cited by 227
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Characteristics of SARS-CoV-2 and COVID-19
Hu, B., Guo, H., Zhou, P., & Shi, Z.-L. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-00459-7 · Cited by 5,291
SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development
Wang, M.-Y., Zhao, R., Gao, L.-J., Gao, X.-F., Wang, D.-P., & Cao, J.-M. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.587269 · Cited by 874
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Meyerowitz, E. A., Richterman, A., Gandhi, R. T., & Sax, P. E. (2021) · Annals of Internal Medicine · doi:10.7326/m20-5008 · Cited by 747
Damas, J., Hughes, G. M., Keough, K. C., Painter, C. A., Persky, N. S., Corbo, M., Hiller, M., Koepfli, K.-P., Pfenning, A. R., Zhao, H., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2010146117 · Cited by 633
In-flight transmission of SARS-CoV-2
Choi, E. M., Chu, D. K. W., Cheng, P. K. C., Tsang, D. N. C., Peiris, M., Bausch, D. G., Poon, L. L. M., & Watson-Jones, D. (2020) · Emerging Infectious Diseases · doi:10.3201/eid2611.203254 · Cited by 76
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Metadata
- Authors
- Sit, T. H. C., Brackman, C. J., Ip, S. M., Tam, K. W. S., Law, P. Y. T., To, E. M. W., Yu, V. Y. T., Sims, L. D., Tsang, D. N. C., Chu, D. K. W., Perera, R. A. P. M., Poon, L. L. M., & Peiris, M.
- Venue
- Nature
- Published
- 2020-05-14
- Volume
- 586
- Issue
- 7831
- Pages
- 776-778
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W3024382268
- Cited by
- 744
- References
- 5
- FWCI
- 17.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Sit, T. H. C., Brackman, C. J., Ip, S. M., Tam, K. W. S., Law, P. Y. T., To, E. M. W., Yu, V. Y. T., Sims, L. D., Tsang, D. N. C., Chu, D. K. W., Perera, R. A. P. M., Poon, L. L. M., & Peiris, M. (2020). Infection of dogs with SARS-CoV-2. Nature. https://doi.org/10.1038/s41586-020-2334-5
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