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Systems vaccinology of the BNT162b2 mRNA vaccine in humans
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“This decreasing trend in monocytes and dendritic cells induced by ARCoV was different from that observed with inactivated vaccines and the BNT162b2 mRNA vaccine [26,[41], [42], [43]].”
From Systemic profiling of immune responses in healthy adults vaccinated with an RBD-targeting COVID-19 mRNA vaccine (2025) · cites this paper as [26]
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“BNT162b2 vaccination induces strong antibody and antigen-specific T-cell responses, and it is associated with a significant expansion of a distinct myeloid cell cluster enriched in interferon-response transcription factors [26,27].”
From Systemic profiling of immune responses in healthy adults vaccinated with an RBD-targeting COVID-19 mRNA vaccine (2025) · cites this paper as [26]
In the citing paper
“This decreasing trend in monocyte and DC proportions contrasts with responses to other vaccines, such as mRNA vaccine BNT162b2 and inactivated vaccine BBIBP-CorV [26,42], possibly due to the shorter antigen encoded by ARCoV and the unmodified uridine [46].”
From Systemic profiling of immune responses in healthy adults vaccinated with an RBD-targeting COVID-19 mRNA vaccine (2025) · cites this paper as [26]
In the citing paper
“The neutralizing antibody stimulated by BNT162b2 showed a negative association with age [26].”
From Systemic profiling of immune responses in healthy adults vaccinated with an RBD-targeting COVID-19 mRNA vaccine (2025) · cites this paper as [26]
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Li, C., Lee, A., Grigoryan, L., Arunachalam, P. S., Scott, M. K. D., Trisal, M., Wimmers, F., Sanyal, M., Weidenbacher, P. A., Feng, Y., et al. (2022) · Nature Immunology · doi:10.1038/s41590-022-01163-9 · Cited by 505
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Metadata
- Authors
- Arunachalam, P. S., Scott, M. K. D., Hagan, T., Li, C., Feng, Y., Wimmers, F., Grigoryan, L., Trisal, M., Edara, V. V., Lai, L., Chang, S. E., Feng, A., Dhingra, S., Shah, M., Lee, A. S., Chinthrajah, S., Sindher, S. B., Mallajosyula, V., Gao, F., Sigal, N., Kowli, S., Gupta, S., Pellegrini, K., Tharp, G., Maysel-Auslender, S., Hamilton, S., Aoued, H., Hrusovsky, K., Roskey, M., Bosinger, S. E., Maecker, H. T., Boyd, S. D., Davis, M. M., Utz, P. J., Suthar, M. S., Khatri, P., Nadeau, K. C., & Pulendran, B.
- ORCID
- Venue
- Nature
- Published
- 2021-07-12
- Volume
- 596
- Issue
- 7872
- Pages
- 410-416
- ISSN
- 0028-0836
- 1476-4687
- PMC
- PMC8761119
- Cited by
- 572
- References
- 20
- Language
- en
- Update notices
- correction (2023-05-24)
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