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Cited by 2,029

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Long-term cardiovascular outcomes of COVID-19

Open access
Xie, Yan, Xu, Evan, Bowe, Benjamin, Al-Aly, Ziyad·2022·Nature Medicine

Abstract

The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively characterized. Here we used national healthcare databases from the US Department of Veterans Affairs to build a cohort of 153,760 individuals with COVID-19, as well as two sets of control cohorts with 5,637,647 (contemporary controls) and 5,859,411 (historical controls) individuals, to estimate risks and 1-year burdens of a set of pre-specified incident cardiovascular outcomes. We show that, beyond the first 30 d after infection, individuals with COVID-19 are at increased risk of incident cardiovascular disease spanning several categories, including cerebrovascular disorders, dysrhythmias, ischemic and non-ischemic heart disease, pericarditis, myocarditis, heart failure and thromboembolic disease. These risks and burdens were evident even among individuals who were not hospitalized during the acute phase of the infection and increased in a graded fashion according to the care setting during the acute phase (non-hospitalized, hospitalized and admitted to intensive care). Our results provide evidence that the risk and 1-year burden of cardiovascular disease in survivors of acute COVID-19 are substantial. Care pathways of those surviving the acute episode of COVID-19 should include attention to cardiovascular health and disease.

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Metadata

Authors
Xie, Y., Xu, E., Bowe, B., & Al-Aly, Z.
Venue
Nature Medicine
Published
2022-02-07
Volume
28
Issue
3
Pages
583-590
ISSN
  • 1078-8956 (ISSN-L)
  • 1546-170X
OpenAlex
W4210511145
Cited by
2,029
References
14
FWCI
213.29
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Long-term cardiovascular outcomes of COVID-19. https://app.cochat.ai/papers/10.1038/s41591-022-01689-3
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Xie, Y., Xu, E., Bowe, B., & Al-Aly, Z. (2022). Long-term cardiovascular outcomes of COVID-19. Nature Medicine. https://doi.org/10.1038/s41591-022-01689-3

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