Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes

STAR: ultrafast universal RNA-seq aligner

Dobin, A., Davis, C. A., Schlesinger, F., Drenkow, J., Zaleski, C., Jha, S., Batut, P., Chaisson, M., & Gingeras, T. R. (2013) · Bioinformatics · doi:10.1093/bioinformatics/bts635 · Cited by 51,709 · see citing works

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Robinson, M. D., McCarthy, D. J., & Smyth, G. K. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp616 · Cited by 41,364 · see citing works

limma powers differential expression analyses for RNA-sequencing and microarray studies

Ritchie, M. E., Phipson, B., Wu, D., Hu, Y., Law, C. W., Shi, W., & Smyth, G. K. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv007 · Cited by 40,458 · see citing works

Modern Applied Statistics with S

Venables, W., & Ripley, B. (2010) · Statisctics and computing/Statistics and computing · doi:10.1007/978-0-387-21706-2 · Cited by 16,188 · see citing works

Tissue-based map of the human proteome

Uhlén, M., Fagerberg, L., Hallström, B. M., Lindskog, C., Oksvold, P., Mardinoglu, A., Sivertsson, Å., Kampf, C., Sjöstedt, E., Asplund, A., et al. (2015) · Science · doi:10.1126/science.1260419 · Cited by 15,286 · see citing works

pROC: an open-source package for R and S+ to analyze and compare ROC curves

Robin, X., Turck, N., Hainard, A., Tiberti, N., Lisacek, F., Sanchez, J.-C., & Müller, M. (2011) · BMC Bioinformatics · doi:10.1186/1471-2105-12-77 · Cited by 13,697 · see citing works

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

Law, C. W., Chen, Y., Shi, W., & Smyth, G. K. (2014) · Genome Biology · doi:10.1186/gb-2014-15-2-r29 · Cited by 6,155 · see citing works

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp

Matsuda, M., & DeFronzo, R. A. (1999) · Diabetes Care · doi:10.2337/diacare.22.9.1462 · Cited by 5,621 · see citing works

The GTEx Consortium atlas of genetic regulatory effects across human tissues

The GTEx Consortium, Aguet, F., Anand, S., Ardlie, K. G., Gabriel, S., Getz, G. A., Graubert, A., Hadley, K., Handsaker, R. E., Huang, K. H., et al. (2020) · Science · doi:10.1126/science.aaz1776 · Cited by 5,547 · see citing works

International Association of Diabetes and Pregnancy Study Groups Recommendations on the Diagnosis and Classification of Hyperglycemia in Pregnancy

International Association of Diabetes and Pregnancy Study Groups Consensus Panel (2010) · Diabetes Care · doi:10.2337/dc09-1848 · Cited by 5,390 · see citing works

Evaluation of High-Sensitivity C-Reactive Protein and Serum Lipid Profile in Southeastern Nigerian Women with Pre-Eclampsia

Onuegbu, A. J., Olisekodiaka, J. M., Udo, J., Umeononihu, O. S., Amah, U. K., Okwara, J. E., & Atuegbu, C. (2015) · Medical Principles and Practice · doi:10.1159/000381778 · Cited by 2,057 · see citing works

Correct Homeostasis Model Assessment (HOMA) Evaluation Uses the Computer Program

Lévy, J., Matthews, D. R., & Hermans, M. P. (1998) · Diabetes Care · doi:10.2337/diacare.21.12.2191 · Cited by 1,997 · see citing works

International Association of Diabetes and Pregnancy Study Groups Recommendations on the Diagnosis and Classification of Hyperglycemia in Pregnancy

Metzger, B. E., Gabbe, S. G., Persson, B., Lowe, L. P., Dyer, A. R., Oats, J. J. N., & Buchanan, T. A. (2010) · Diabetes Care · doi:10.2337/dc10-0719 · Cited by 1,888 · see citing works

ACOG Practice Bulletin No. 190: Gestational Diabetes Mellitus

(2018) · Obstetrics &amp; Gynecology · doi:10.1097/aog.0000000000002501 · Cited by 1,820 · see citing works

Cellular Mechanisms for Insulin Resistance in Normal Pregnancy and Gestational Diabetes

Barbour, L. A., McCurdy, C. E., Hernandez, T. L., Kirwan, J. P., Catalano, P. M., & Friedman, J. E. (2007) · Diabetes Care · doi:10.2337/dc07-s202 · Cited by 811 · see citing works

TNF-α Is a Predictor of Insulin Resistance in Human Pregnancy

Kirwan, J. P., Hauguel-De Mouzon, S., Lepercq, J., Challier, J.-C., Huston-Presley, L., Friedman, J. E., Kalhan, S. C., & Catalano, P. M. (2002) · Diabetes · doi:10.2337/diabetes.51.7.2207 · Cited by 738 · see citing works

Gestational Diabetes and Insulin Resistance: Role in Short- and Long-Term Implications for Mother and Fetus

Catalano, P. M., Kirwan, J. P., Mouzon, S. H., & King, J. C. (2003) · Journal of Nutrition · doi:10.1093/jn/133.5.1674s · Cited by 495 · see citing works

10. Cardiovascular Disease and Risk Management: <i>Standards of Care in Diabetes—2023</i>

ElSayed, N. A., Aleppo, G., Aroda, V. R., Bannuru, R. R., Brown, F. M., Bruemmer, D., Collins, B. S., Das, S. R., Hilliard, M. E., Isaacs, D., et al. (2023) · Diabetes Care · doi:10.2337/dc23-s010 · Cited by 465 · see citing works

A single-cell survey of the human first-trimester placenta and decidua

Suryawanshi, H., Morozov, P. S., Straus, A., Sahasrabudhe, N., Max, K. E. A., Garzia, A., Kustagi, M., Tuschl, T., & Williams, Z. (2018) · Science Advances · doi:10.1126/sciadv.aau4788 · Cited by 439 · see citing works

Roles of insulin-like growth factor (IGF) binding proteins in regulating IGF actions

Duan, C., & Xu, Q. (2005) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2004.12.022 · Cited by 354 · see citing works

15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2023

ElSayed, N. A., Aleppo, G., Aroda, V. R., Bannuru, R. R., Brown, F. M., Bruemmer, D., Collins, B. S., Hilliard, M. E., Isaacs, D. M., Johnson, E. L., et al. (2022) · Diabetes Care · doi:10.2337/dc23-s015 · Cited by 309 · see citing works

Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat. Comparison with insulin.

Jacob, R. J., Barrett, E. J., Plewe, G., Fagin, K. D., & Sherwin, R. S. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114072 · Cited by 290 · see citing works

IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

Wheatcroft, S. B., & Kearney, M. T. (2009) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2009.01.002 · Cited by 278 · see citing works

Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies

Teschendorff, A. E., Zhuang, J. J., & Widschwendter, M. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr171 · Cited by 259 · see citing works

Obesity and preeclampsia: the potential role of inflammation*1

Wolf, M. S. (2001) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(01)01551-4 · Cited by 257 · see citing works

Heterogeneous Contribution of Insulin Sensitivity and Secretion Defects to Gestational Diabetes Mellitus

Powe, C. E., Allard, C., Battista, M., Doyon, M., Bouchard, L., Ecker, J. L., Perron, P., Florez, J. C., Thadhani, R., & Hivert, M. (2016) · Diabetes Care · doi:10.2337/dc15-2672 · Cited by 242 · see citing works

Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., CROMER, S. J., et al. (2023) · Nature Medicine · doi:10.1038/s41591-023-02502-5 · Cited by 229 · see citing works

Insulin requirements throughout pregnancy in women with type 1 diabetes mellitus: three changes of direction

García-Patterson, A., Gich, I., Amini, S. B., Catalano, P. M., de Leiva, A., & Corcoy, R. (2010) · Diabetologia · doi:10.1007/s00125-009-1633-z · Cited by 220 · see citing works

Clinically Useful Estimates of Insulin Sensitivity During Pregnancy

Kirwan, J. P., Huston-Presley, L., Kalhan, S. C., & Catalano, P. M. (2001) · Diabetes Care · doi:10.2337/diacare.24.9.1602 · Cited by 218 · see citing works

Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1

Powell, D. R., Suwanichkul, A., Cubbage, M. L., DePaolis, L. A., Snuggs, M. B., & Lee, P. D. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55144-9 · Cited by 217 · see citing works

The role of PAPP-A in the IGF system: location, location, location

Oxvig, C. (2015) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-015-0259-9 · Cited by 200 · see citing works

Human Placental Lactogen: Studies of Its Acute Metabolic Effects and Disposition in Normal Man*

Beck, P. A., & Daughaday, W. H. (1967) · Journal of Clinical Investigation · doi:10.1172/jci105503 · Cited by 199 · see citing works

Insulin-Like Growth Factor-I Stimulates Both Cell Growth and Lipogenesis during Differentiation of Human Mesenchymal Stem Cells into Adipocytes

Scavo, L. M., Karas, M., Murray, M., & LeRoith, D. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031682 · Cited by 157 · see citing works

Insulin-Like Growth Factor Axis and Risk of Type 2 Diabetes in Women

Rajpathak, S. N., He, M., Sun, Q., Kaplan, R. C., Muzumdar, R. H., Rohan, T. E., Gunter, M. J., Pollak, M., Kim, M., Pessin, J. E., et al. (2012) · Diabetes · doi:10.2337/db11-1488 · Cited by 148 · see citing works

The Insulin-Like Growth Factor System in Obesity, Insulin Resistance and Type 2 Diabetes Mellitus

LEWITT, M. S., Dent, M., & Hall, K. E. (2014) · Journal of Clinical Medicine · doi:10.3390/jcm3041561 · Cited by 144 · see citing works

Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

Rajwani, A., Ezzat, V., Smith, J., Yuldasheva, N. Y., Duncan, E. R., Gage, M., Cubbon, R. M., Kahn, M., Imrie, H., Abbas, A., et al. (2012) · Diabetes · doi:10.2337/db11-0963 · Cited by 135 · see citing works

RNA-SeQC 2: efficient RNA-seq quality control and quantification for large cohorts

Graubert, A., Aguet, F., Ravi, A., Ardlie, K., & Getz, G. A. (2021) · Bioinformatics · doi:10.1093/bioinformatics/btab135 · Cited by 132 · see citing works

Relaxin in Human Pregnancy

Goldsmith, L. T., & Weiss, G. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2008.03800.x · Cited by 114 · see citing works

Augmented insulin secretory response in early pregnancy

Powe, C. E., Presley, L. H., Locascio, J. J., & Catalano, P. M. (2019) · Diabetologia · doi:10.1007/s00125-019-4881-6 · Cited by 99 · see citing works

Genetics of Glucose regulation in Gestation and Growth (Gen3G): a prospective prebirth cohort of mother–child pairs in Sherbrooke, Canada

Guillemette, L., Allard, C., Lacroix, M., Patenaude, J., Battista, M., Doyon, M., Moreau, J., Ménard, J., Bouchard, L., Ardilouze, J., et al. (2016) · BMJ Open · doi:10.1136/bmjopen-2015-010031 · Cited by 98 · see citing works

Comparison of the effects of recombinant human insulin-like growth factor-I and insulin on glucose and leucine kinetics in humans.

Laager, R., Ninnis, R., & Keller, U. B. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116783 · Cited by 91 · see citing works

Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA

Chen, J., Behnam, E., Huang, J., Moffatt, M. F., Schaid, D. J., Liang, L., & Lin, X. (2017) · BMC Genomics · doi:10.1186/s12864-017-3808-1 · Cited by 89 · see citing works

Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene

López‐Tello, J., Yong, H. E. J., Sandovici, I., Dowsett, G. K. C., Christoforou, E. R., Salazar‐Petres, E., Boyland, R., Napso, T., Yeo, G. S. H., Lam, B., et al. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.06.007 · Cited by 83 · see citing works

Defining Heterogeneity Among Women With Gestational Diabetes Mellitus

Powe, C. E., Hivert, M., & Udler, M. S. (2020) · Diabetes · doi:10.2337/dbi20-0004 · Cited by 77 · see citing works

Increasing insulin resistance predicts adverse pregnancy outcomes in women with gestational diabetes mellitus

Sun, Y., Juan, J., Xu, Q., Su, R., Hirst, J. E., & Yang, H. (2019) · Journal of Diabetes · doi:10.1111/1753-0407.13013 · Cited by 73 · see citing works

Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance.

Crossey, P. A., Jones, J. S., & Miell, J. P. (2000) · Diabetes · doi:10.2337/diabetes.49.3.457 · Cited by 72 · see citing works

Low levels of insulin-like growth-factor-binding protein-1 (IGFBP-1) are prospectively associated with the incidence of type 2 diabetes and impaired glucose tolerance (IGT): The Söderåkra Cardiovascular Risk Factor Study

Petersson, U., Östgren, C. J., Brudin, L. H., Brismar, K., & Nilsson, P. M. (2009) · Diabetes & Metabolism · doi:10.1016/j.diabet.2008.11.003 · Cited by 66 · see citing works

Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain

Haywood, N. J., Cordell, P. A., Tang, K. Y., Makova, N., Yuldasheva, N. Y., Imrie, H., Viswambharan, H., Bruns, A. F., Cubbon, R. M., Kearney, M. T., et al. (2016) · Diabetes · doi:10.2337/db16-0997 · Cited by 59 · see citing works

Metabolic phenotypes of early gestational diabetes mellitus and their association with adverse pregnancy outcomes

Immanuel, J., Simmons, D. S., Harreiter, J., Desoyé, G., Corcoy, R., Adelantado, J. M., Devlieger, R., Lapolla, A., Dalfrà, M. G., Bertolotto, A., et al. (2020) · Diabetic Medicine · doi:10.1111/dme.14413 · Cited by 53 · see citing works

The Stanniocalcin-PAPP-A-IGFBP-IGF Axis

Oxvig, C., & Conover, C. A. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad053 · Cited by 52 · see citing works

Distinct Insulin Physiology Trajectories in Euglycemic Pregnancy and Gestational Diabetes Mellitus

Thaweethai, T., Soetan, Z. O., James, K. E., Florez, J. C., & Powe, C. E. (2023) · Diabetes Care · doi:10.2337/dc22-2226 · Cited by 52 · see citing works

IGFBP-1 and IGF-I as markers for advanced fibrosis in NAFLD – a pilot study

Hagström, H., Stal, P. I., Hultcrantz, R. W., Brismar, K., & Ansurudeen, I. (2017) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2017.1379556 · Cited by 45 · see citing works

Refining the diagnosis of gestational diabetes mellitus: a systematic review and meta-analysis

Francis, E. C., Powe, C. E., Lowe, W. L., White, S. L., Scholtens, D. M., Yang, J., Zhu, Y., Zhang, C., Hivert, M., Kwak, S. H., et al. (2023) · Communications Medicine · doi:10.1038/s43856-023-00393-8 · Cited by 45 · see citing works

Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1

Qiao, L., Wattez, J.-S., Lee, S., Guo, Z., Schaack, J. B., Hay, W. W., Moretto-Zita, M., Parast, M. M., & Shao, J. (2016) · Diabetologia · doi:10.1007/s00125-016-4061-x · Cited by 43 · see citing works

The growth hormone–insulin-like growth factor axis in pregnancy

Kaur, H., Mühlhäusler, B. S., Roberts, C. T., & Gatford, K. L. (2021) · Journal of Endocrinology · doi:10.1530/joe-21-0087 · Cited by 43 · see citing works

Activation of the insulin-like growth factor binding protein-1 promoter by progesterone receptor in decidualized human endometrial stromal cells

Gao, J., Mazella, J., Suwanichkul, A., Powell, D. R., & Tseng, L. (1999) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(99)00096-9 · Cited by 41 · see citing works

Gestational Diabetes Mellitus and Energy-Dense Diet: What Is the Role of the Insulin/IGF Axis?

Martín‐Estal, I., & Castorena‐Torres, F. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.916042 · Cited by 37 · see citing works

Do variations in insulin sensitivity and insulin secretion in pregnancy predict differences in obstetric and neonatal outcomes?

Madsen, L. R., GIBBONS, K. S., Ronald, C. W., Tam, W. H., Catalano, P. M., Sacks, D. A., LOWE, J. M., & McIntyre, D. H. (2020) · Diabetologia · doi:10.1007/s00125-020-05323-0 · Cited by 37 · see citing works

Effects of Combined Recombinant Insulin-Like Growth Factor (IGF)-I and IGF Binding Protein-3 in Type 2 Diabetic Patients on Glycemic Control and Distribution of IGF-I and IGF-II among Serum Binding Protein Complexes

Clemmons, D. R., Sleevi, M., Allan, G., & Sommer, A. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2699 · Cited by 34 · see citing works

Roles of insulin resistance and beta cell dysfunction in macrosomia among Chinese women with gestational diabetes mellitus

Li, J., Leng, J., Li, W., Zhang, C., Feng, L., Wang, P., Chan, J. C. N., Hu, G., Yu, Z., & Yang, X. (2018) · Primary care diabetes · doi:10.1016/j.pcd.2018.07.010 · Cited by 33 · see citing works

Optimising Cardiometabolic Risk Factors in Pregnancy: A Review of Risk Prediction Models Targeting Gestational Diabetes and Hypertensive Disorders

Thong, E. P., Ghelani, D. P., Manoleehakul, P., Yesmin, A., Slater, K., Taylor, R., Collins, C. E., Hutchesson, M., Lim, S. S., Teede, H. J., et al. (2022) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd9020055 · Cited by 28 · see citing works

Performance of early risk assessment tools to predict the later development of gestational diabetes

Kotzaeridi, G., Blätter, J., Eppel, D., Rosicky, I., Mittlböck, M., Yerlikaya‐Schatten, G., Schatten, C., Husslein, P., Eppel, W., Huhn, E. A., et al. (2021) · European Journal of Clinical Investigation · doi:10.1111/eci.13630 · Cited by 27 · see citing works

Regulation of IGFBP-1 in Metabolic Diseases.

Bae, J., Song, D., & Im, S. (2013) · Europe PMC (PubMed Central) · Cited by 26 · see citing works

Contribution of gestational diabetes mellitus heterogeneity and prepregnancy body mass index to large‐for‐gestational‐age infants—A retrospective case‐control study

Wang, N., Song, L., Sun, B., Peng, Y., Fei, S., Cui, J., Mi, Y., & Cui, W. (2020) · Journal of Diabetes · doi:10.1111/1753-0407.13113 · Cited by 25 · see citing works

Regulating needs: Exploring the role of insulin-like growth factor-2 signalling in materno-fetal resource allocation

Sferruzzi-Perri, A. N. (2018) · Placenta · doi:10.1016/j.placenta.2018.01.005 · Cited by 24 · see citing works

Second Trimester Insulin Resistance, Early Pregnancy Body Mass Index and Gestational Weight Gain

Stuebe, A. M., McElrath, T. F., Thadhani, R., & Ecker, J. L. (2009) · Maternal and Child Health Journal · doi:10.1007/s10995-009-0449-2 · Cited by 21 · see citing works

Insulin-Like Growth Factor Axis Biomarkers and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

Wang, X., Wang, W., Yu, X., Hua, X., Ouyang, F., & Luo, Z. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00444 · Cited by 20 · see citing works

IGFBP-1 in Cardiometabolic Pathophysiology—Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice

Haywood, N. J., Slater, T. A., Drozd, M., Warmke, N., Matthews, C., Cordell, P. A., Smith, J., Rainford, J., Cheema, H. K., Maher, C., et al. (2019) · Journal of the Endocrine Society · doi:10.1210/jendso/bvz006 · Cited by 16 · see citing works

Maternal insulin‐like growth factors and insulin‐like growth factor‐binding proteins for macrosomia prediction in diabetic and nondiabetic pregnancy: A prospective study

Николаевна, А. Е., Babakov, V., Selkov, S. А., Renzo, G. C. D., Kogan, I. Y., & Kapustin, R. V. (2023) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.14696 · Cited by 10 · see citing works

Pathophysiology from preconception, during pregnancy, and beyond.

Hivert, M.-F., Backman, H., Benhalima, K., Catalano, P., Desoye, G., Immanuel, J., McKinlay, C. J. D., Meek, C. L., Nolan, C. J., Ram, U., et al. (2024) · The Lancet · doi:10.1016/s0140-6736(24)00827-4 · Cited by 186 · see citing works

The pathogenesis, diagnosis, and treatment of chronic endometritis: a comprehensive review

Yan, X., Jiao, J., & Wang, X. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1603570 · Cited by 41 · see citing works

Deciphering DNA Methylation in Gestational Diabetes Mellitus: Epigenetic Regulation and Potential Clinical Applications

Li, N., Liu, H., & Liu, S.-M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25179361 · Cited by 16 · see citing works

Influence of gestational diabetes mellitus on the cardiovascular system and its underlying mechanisms

Zhang, Z., Zhang, Y., Huang, S., Li, M., Li, L., Qi, L., He, Y., Xu, Z., & Tang, J. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1474643 · Cited by 17 · see citing works

Transgenerational effects on the gene transcriptome of chicken liver

Gao, M., Chen, Y., Fan, H., Chen, S., Wang, H., Nie, W., Guo, Y., & Lv, Z. (2024) · Animal Advances · doi:10.48130/animadv-0024-0003 · Cited by 13 · see citing works

Molecular regulation and functional benefits of trophoblast syncytialization in optimizing maternal-fetal nutrient allocation

Li, Q., Zhu, Y. J., Yu, X., Shao, X., & Wang, Y. (2025) · Placenta · doi:10.1016/j.placenta.2025.06.003 · Cited by 11 · see citing works

Burden of type 2 diabetes due to high body mass index in different SDI regions and projections of future trends: insights from the Global Burden of Disease 2021 study

Ding, Y.-F., Deng, A., Qi, T., Yu, H., Wu, L., & Zhang, H. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-024-01554-y · Cited by 10 · see citing works

Fetal sex-specific differences in the placental transcriptome of gestational diabetes

Shook, L. L., White, F., Acharya, K. D., Torres-Bigio, S. I., Ibanez-Pintor, L. C., Han, D., Aguet, F., Ardlie, K., Florez, J. C., Bouchard, L., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-39975-6 · Cited by 8 · see citing works

Genetics of glucose homeostasis in pregnancy and postpartum

Lowe, W. L., Kuang, A., Hayes, M. G., Hivert, M., & Scholtens, D. M. (2024) · Diabetologia · doi:10.1007/s00125-024-06256-8 · Cited by 8 · see citing works

Mechanisms of Fetal Overgrowth in Gestational Diabetes: The Potential Role of SOCS2

Hernández-Baraza, L., Brito‐Casillas, Y., Valverde‐Tercedor, C., Recio, C., Fernández‐Pérez, L., Guerra, B., & Wägner, A. M. (2025) · Nutrients · doi:10.3390/nu17091519 · Cited by 8 · see citing works

Plant Heteropolysaccharides as Potential Anti-Diabetic Agents: A Review

He, D., & Cui, C. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47070533 · Cited by 7 · see citing works

Proteomic Signature of BMI and Risk of Type 2 Diabetes

Wang, X., Ma, H., Kou, M., Heianza, Y., Fonseca, V. A., & Qi, L. (2024) · Diabetes · doi:10.2337/db24-0329 · Cited by 7 · see citing works

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

Du, R., Wang, F., Li, L., & Wang, Q. (2025) · Obesity Reviews · doi:10.1111/obr.70048 · Cited by 7 · see citing works

Stopping the Intergenerational Risk of Diabetes—From Mechanisms to Interventions: A Report on Research Supported by Pathway to Stop Diabetes

Harnois‐Leblanc, S., & Hivert, M. (2024) · Diabetes · doi:10.2337/dbi24-0014 · Cited by 7 · see citing works

Cohort profile: the Genetics of Glucose regulation in Gestation and Growth (Gen3G) – a prospective prebirth cohort of mother–child pairs in Sherbrooke, Canada, 3-year and 5-year follow-up visits

Taschereau, A., Doyon, M., Arguin, M., Allard, C., Desgagné, V., Côté, A., Massé, É., Jacques, P., Perron, P., Hivert, M., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-093434 · Cited by 6 · see citing works

Multiorgan Regulation Mechanisms and Nutritional Intervention Strategies in Gestational Diabetes Mellitus

Zhuang, M., Wang, B., Shi, Y., & Zhou, Z. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.04.008 · Cited by 5 · see citing works

The potential of circulating free DNA of methylated IGFBP as a biomarker for type 2 diabetes Mellitus: A Comprehensive review

Belinda, A., Humardani, F. M., Putra, S. E. D., & Widyadhana, B. (2024) · Clinica Chimica Acta · doi:10.1016/j.cca.2024.120104 · Cited by 4 · see citing works

Metabolomic signatures of prenatal per- and polyfluoroalkyl substance exposure and subtypes of gestational diabetes mellitus: A prospective cohort study

Zhang, T., Liu, L., Zhang, Q., Jiang, W. H., Huang, Y., Ye, W., Zhang, N., & Zhang, J. (2026) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2026.141652 · Cited by 3 · see citing works

Long-read assembly reveals vast transcriptional complexity in the placenta associated with metabolic and endocrine function

Bresnahan, S. T., Yong, H. E. J., Nemani, A., Wu, W. H., Lopez, S., Chan, J. K. Y., White, F., Jacques, P., Hivert, M., Chan, S.-Y., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71303-4 · Cited by 7 · see citing works

Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior

Gunter‐Rahman, F., Mallett, S., White, F., Jacques, P., Raju, R. M., Hivert, M., & Lee, E. A. (2025) · iScience · doi:10.1016/j.isci.2025.112636 · Cited by 3 · see citing works

Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effectsPreprint

Nunes, C. B., Rukins, V., Cissé, A. H., White, F., McBride, N., Kuang, A., Allard, C., Ronkainen, J., Hughes, A., Elliott, A., et al. (2025) · medRxiv · doi:10.1101/2025.08.19.25333735 · Cited by 3 · see citing works

Insulin Resistance in GDM A1 vs Healthy Pregnancy: A Comparative Study Using METS-IR and TyG Index

Jiang, H., Shang, M., & Gao, S. (2025) · International Journal of Women s Health · doi:10.2147/ijwh.s557974 · Cited by 2 · see citing works

DHA ameliorates GDM placental angiogenesis by regulating HAMP-mediated iron imbalance

Huang, Z., Zhou, S., Cui, Z., Li, J., Liu, L., Feng, X., Ye, H., Ma, K., Huang, S., Xiang, Q., et al. (2026) · Journal of Advanced Research · doi:10.1016/j.jare.2026.03.005 · Cited by 2 · see citing works

Trimester-specific gestational weight gain and adverse outcomes in GDM women: a retrospective cohort study

Yuan, P., Huang, J., Wan, J., Yu, L., Li, J. J., Huang, B., Li, N., Wei, H., Kong, L., & Qin, J. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1861824 · Cited by 2 · see citing works

Evaluating endometrial response to human chorionic gonadotropin: alterations in epigenetic regulation and extracellular vesicle cargo of endometrial stromal cells

Žukauskaitė, D., Girniūtė, E., & Navakauskienė, R. (2025) · Human Reproduction Open · doi:10.1093/hropen/hoaf051 · Cited by 2 · see citing works

Novel role of NR1D1 and SLC7A5 in gestational diabetes mellitus: regulation of polyamine metabolism

Wang, Z., Fang, G., Yao, Y., & Wang, J. (2025) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-025-01691-9 · Cited by 1 · see citing works

Integrating transcriptomic and epigenomic data to identify potential biomarkers in gestational diabetes mellitus patients

Mitra, T., Yadav, D. V., Sajeetha Kumari, R., Agrawal, P., & Janardhanan, R. (2025) · Scientific Reports · doi:10.1038/s41598-025-18018-6 · Cited by 1 · see citing works

Emerging biomarkers for gestational diabetes mellitus and related pediatric outcomes

Gautam, T., Shamsad, A., Singh, R., & Banerjee, M. (2025) · World Journal of Clinical Pediatrics · doi:10.5409/wjcp.v14.i4.109476 · Cited by 1 · see citing works

Targeting of NF‐κB/NLRP3 Axis in Gestational Diabetes Mellitus

Khatap, A. M. F., Al-Kuraishy, H. M., Al-Maiahy, T. J., Al-Gareeb, A. I., Eliwa, D., Saleh, A. M., Abdel‐Aziz, H. R., & Batiha, G. E. (2025) · American Journal of Reproductive Immunology · doi:10.1111/aji.70188 · Cited by 2 · see citing works

Mediating role of body mass index and fetal fraction in the association between advanced maternal age and gestational diabetes mellitus risk: a retrospective non-invasive prenatal testing cohort study

Zhang, B., Zhan, Z., Chen, X., Xi, S., Shi, Z., & Yuan, X. (2026) · European journal of medical research · doi:10.1186/s40001-026-04042-3 · Cited by 1 · see citing works

Long-read transcriptome assembly reveals vast transcriptional complexity in the placenta associated with metabolic and endocrine functionPreprint

Bresnahan, S. T., Yong, H. E. J., Wu, W. H., Lopez, S., Chan, J. K. Y., White, F., Jacques, P., Hivert, M., Chan, S., Love, M. I., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.26.661362 · Cited by 1 · see citing works

Molecular analysis of spinal nerve sheath tumors has identified CSH1 as a candidate gene for differentiating between Schwannomatosis and Spinal schwannomaPreprint

Shi, G., Ren, H., Zhao, D., Zhao, Q., Chen, H., Luo, X., Zhao, J., Yan, S., & Bu, W. (2024) · Research Square · doi:10.21203/rs.3.rs-4816088/v1

IGFBP1 and routine laboratory Indicators for early prediction of pre-eclampsia in Chinese populationPreprint

Qi, H., Zhang, X., Li, J., Hou, G., Zhou, N., Zhao, Z., Xu, W., Diao, Z., Qiu, Z., Chen, S., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4957726/v1

Placental weight as a predictor of future health: Insights from a large-scale genome-wide association study

Zhang, Q., Xu, T., Wu, S., Wu, S., Ye, Y., Wu, H., & Zhang, J. (2025) · Placenta · doi:10.1016/j.placenta.2025.03.006

Correlation Analysis of Serum Pannexin-1 Expression and Insulin Resistance in Patients with Gestational Diabetes Mellitus

李, 康. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.1541176

IGFBP1 orchestrates metabolic reprogramming to drive clear cell renal cell carcinoma progression through NR1H4-mediated lipid homeostasis disruption

Sun, Y., Hao, Y., Peng, F., Ling, H., Sun, K., Qiu, J., Yang, T., Zhao, L., & Xia, Q. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03904-w

Genome-Wide Identification and Analysis of the Igfbp Gene Family in Sea UrchinsPreprint

Li, G., Mu, J. L., Lan, Y.-W., Liu, L.-X., Liu, M., Han, Y., & Shen, X.-H. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5389239

Adverse Effects of Furan on Fetal Development, Growth Plate Integrity, and Placental Functioning in Wistar Rats

Abd‐Allah, E. R., Abdelaziz, H., Eldebss, T. M. A., & El‐Rahman, H. A. A. (2025) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70526

Perillaldehyde Attenuates Insulin Resistance and High Glucose-Induced Ferroptosis in Trophoblast Cells via Regulation of PTPN1/Akt/Foxo1 Signaling Pathway

Wang, X., Lu, Y., Wang, S., Wang, X., Yang, S., & Zhao, C. (2025) · Reproductive Sciences · doi:10.1007/s43032-025-02008-0

Discovery of placental microRNAs associated with maternal insulin sensitivity during pregnancy

Majid, S., Soukar, I., White, F., Allard, C., Aguet, F., Ardlie, K., Florez, J. C., Edlow, A. G., Jacques, P., Karumanchi, S. A., et al. (2025) · Placenta · doi:10.1016/j.placenta.2025.10.021

Dual‐center prospective validation of an early second‐trimester predictive model integrating BMI trajectories and pathophysiological biomarkers for gestational diabetes risk stratification

Gao, J., Song, S., Duo, Y., Qiao, X., Zhang, Y., Xu, J., Zhang, J., Nie, X., Sun, Q., Yang, X., et al. (2025) · Journal of Diabetes Investigation · doi:10.1111/jdi.70179

Placental expression of GKN1 and diminished pancreatic beta cell function during pregnancy

Powe, C. E., White, F., Allard, C., Shook, L. L., Edlow, A. G., Bouchard, L., Aguet, F., Jacques, P., Ardlie, K., Florez, J. C., et al. (2025) · Diabetologia · doi:10.1007/s00125-025-06623-z

Treatment of Gestational Diabetes: Molecular Transport Mechanisms, Shear Stress Adaptation, and Efficacy Comparison Between Liraglutide and Insulin

Liu, L. J., & Chu, Q. (2026) · Journal of Engineering and Science in Medical Diagnostics and Therapy · doi:10.1115/1.4070794

LASSO regression-derived first-trimester (9–14+6 weeks) risk stratification model for gestational diabetes mellitus: development, validation, and open-access web tool in a retrospective Chinese cohort

Wang, X., Zhang, J. S., Zhan, S., & Xu, X. (2026) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-026-08353-y

IGFBP1 is a potential monitoring biomarker of disease activity in elderly patients with inflammatory bowel disease

Yang, S., Jiang, T., Shi, Z., Zhou, F., Yu, H., Huang, J., Li, X., Guo, J., Zhao, H., Zhang, Q., et al. (2026) · Current Molecular Pharmacology · doi:10.1016/j.cmp.2026.02.001

The association of parental use of new tobacco products and combustible cigarettes with nausea and vomiting in pregnancy: a cross-sectional study

Akiyama, M. O., Michikawa, T., Takeda, Y., Nagasaki, S., Sakuma, J., Asakura, K., Nakata, M., & Nishiwaki, Y. (2026) · Environmental Health and Preventive Medicine · doi:10.1265/ehpm.25-00416

Maternal Continuous Glucose Monitoring–Placenta–Fetus Axis: A Systematic Review of CGM Metrics Linked to Placental Vascular Pathology and Fetal Outcomes, with a Sentinel Discordant Case

Andonotopo, W., Bachnas, M. A., Prabowo, W., Yuliantara, E. E., Pramono, M. B. A., Dewantiningrum, J., Lukas, E., Sanjaya, I. N. H., Wiradnyana, A. A. G. P., Kusuma, A. A. N. J., et al. (2026) · Bangladesh Journal of Endocrinology and Metabolism · doi:10.4103/bjem.bjem_6_26

Maternal Hyperglycemia and Adult Offspring Overweight and Obesity: Is Birthweight a Mediator?

McWhorter, K. L., Wells, G., Bowers, K. A., Summer, S. S., Dolan, L. M., Catalano, P. M., Szczesniak, R. D., Altaye, M., Rosenn, B., Khoury, J. C., et al. (2026) · American Journal of Perinatology · doi:10.1055/a-2848-3544

The Impact of the Severity of Preeclampsia on Maternal IGF-1 Serum Levels and Fetal Outcomes: A Case–Control Analysis

Al-Kaabi, A. A. H., Jasim, S. D., Al-Rubaye, Z. J. M., Mohammad, H. Q., & Almusawi, A. A. H. (2026) · Medical Journal of Babylon · doi:10.4103/mjbl.mjbl_882_24

The triglyceride glucose-body mass index and the risk of gestational diabetes mellitus: a systematic review and meta-analysis

Sun, J. F., Chen, Y., Chen, J., Zhao, T., Dong, H., Wang, H., Nan, Z., & Dai, B. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1833116

ENPP1-dependent USP2 ubiquitination governs SQSTM1-mediated autophagy-dependent ferroptosis in trophoblast cells and exacerbates placental dysfunction in gestational diabetes mellitus

Xu, Y., Zhong, G., Cheng, X., Yan, J., Zhou, Y., Feng, Y., & Fan, R. (2026) · The Journal of Immunology · doi:10.1093/jimmun/vkag127

Tissue origins of the plasma proteomic response to glucose ingestion in humans

Uluvar, B., Williamson, A., Kolnes, K. J., Jeppesen, P. B., Kolnes, A. J., Koprulu, M., Zoodsma, M., Beuchel, C. F., Bambal, Y., Reinés, M., et al. (2026) · Diabetologia · doi:10.1007/s00125-026-06800-8

Exploration of Early Biomarkers for Gestational Diabetes Mellitus in Pregnant Women Living Without Obesity

Wu, D., Xu, M., Zhang, C., Li, S., Yao, L., Geng, M., Guo, Y., Wei, Z., & Li, W. (2026) · Journal of Diabetes Research · doi:10.1155/jdr/9762300

Placental transcriptomics identifies a candidate HLA-DQA2-FGL2 immune signature in gestational diabetes mellitus

Liu, S., Feng, J., Ding, Y., & Liang, W. (2026) · Placenta · doi:10.1016/j.placenta.2026.08.339

Maternal per- and polyfluoroalkyl substances exposure and the co-occurrence of gestational diabetes mellitus and preeclampsia/eclampsia: a nested case–control study

Li, N., Li, L., Deng, Y., Wang, M., Li, Y., Liu, Z., Kang, H., Zhu, J., Yu, P., & Wang, Y. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1929511

The redox architecture of gestational diabetes mellitus: from cellular stress engine to epigenetic and mitochondrial rewiring

Zhang, H., Zhang, S., Liu, Y., Shi, J., Aijun, Y., Jin, R., Jin, Y., Wang, X., Fan, Y., Liu, Q., et al. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.09.006

Trimester-specific reference interval for glycated hemoglobin in non-diabetic pregnant women: A cross-sectional study

Takiso, K. T., Tsegaye, A., Mengistu, M., Woldesenbet, A., & Lemine, A. A. (2026) · Clinics · doi:10.1016/j.clinsp.2026.101160

Placental Insulin-like Growth Factor Signaling and Neurodevelopment: Emerging Evidence from the Placenta–Brain Axis

Carver, A. J., Williamson, E. G., & Stevens, H. E. (2026) · Cells · doi:10.3390/cells15191759

Uncovering Placental Endocrine Dysregulation in Gestational Diabetes Mellitus Using Bioinformatics and Machine Learning

Deng, L., Yang, M., Wang, X., Gong, N., Zhang, N., Yang, Q., & Gu, C. (2026) · American Journal of Reproductive Immunology · doi:10.1111/aji.70325

Future direction and international collaborations

Hod, M., Berghella, V., Shen, G. X., & McLaren, R. A. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-13265-0.00025-2

Neighborhood walkability and gestational diabetes mellitus: a review of epidemiological evidence and potential mechanisms

Mu, Q., Jiawei, F. A. N. G., Guangdi, C. H. E. N., & Du, W. (2026) · Journal of Zhejiang University (Medical Sciences) · doi:10.3724/zdxbyxb-2026-0030

Second-Trimester Ambient Temperature and Risk of Gestational Diabetes Mellitus: A Large Retrospective Cohort Study in Beijing

Guo, C., Yang, Q., Wei, Y., Wang, Z., & Qian, Y. (2026) · Environmental Risk · doi:10.1016/j.envr.2026.100020

279-OR: Placental IGFBP1 Is Associated with Insulin Sensitivity during Pregnancy and Is an Early Biomarker for Gestational Diabetes

Hivert, M., White, F., Allard, C., James, K. E., MAJID, S., Florez, J. C., Edlow, A. G., Bouchard, L., Jacques, P., Karumanchi, S. A., et al. (2023) · Diabetes · doi:10.2337/db23-279-or

Placental lactogen, placental growth factor, insulin resistance in early pregnancy and risk for gestational diabetes

Popova, P., Tkachuk, A., Владимировна, Д. А., Bolotko, Y., & Grineva, E. N. (2016) · Problems of Endocrinology · doi:10.14341/probl201662531-32 · Cited by 2 · see citing works

Maternal plasma concentrations of IGF-1, IGFBP-1, and C-peptide in early pregnancy and subsequent risk of gestational diabetes mellitus

Qiu, C., Vadachkoria, S., Meryman, L., Frederick, I. O., & Williams, M. A. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.04.015 · Cited by 50 · see citing works

Effects of glucose on placental hormones in the human term placenta in vitro.

Tt, H., Chen, K.-C., Hsu, J., Th, C., Cc, H., & Wang, H. S. (1997) · PubMed · Cited by 1 · see citing works

Role of placental fibrinogen-like protein 1 in gestational diabetes

Kang, L., Li, H., Ou, H., Wu, P., Wang, S., Chang, C., Lin, S., Wu, C., & Wu, H. (2020) · Translational research · doi:10.1016/j.trsl.2020.01.001 · Cited by 28 · see citing works