Pancancer survival analysis of cancer hallmark genes

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

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Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer

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Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

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Unraveling the mechanisms of RECQL4-mediated cervical cancer progression through the PI3K/AKT pathway

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The impact of ERP29 on the progression of pharyngeal squamous cell carcinoma

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The antitumor peptide M1-20 induced the degradation of CDK1 through CUL4-DDB1-DCAF1-involved ubiquitination

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Inhibitory DNA Aptamer Tools against SOCS3-gp130 Interactions

Zhang, X., Hou, Y., Chen, W., Fu, T., Wei, Y., & Tan, W. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c09252 · Cited by 4

AH-6809 mediated regulation of lung adenocarcinoma metastasis through NLRP7 and prognostic analysis of key metastasis-related genes

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IGF2BP3 prefers to regulate alternative splicing of genes associated with the progression of gastric cancer in AGS cells

Zeng, X., Zhang, Y., Shapaer, T., Abudoukelimu, A., Zhao, Z., & Ma, B. (2025) · Discover Oncology · doi:10.1007/s12672-025-01880-1 · Cited by 4

Diagnostic, prognostic, and immunological roles of NCAPG in pan-cancer: A bioinformatics analysis

Fang, M., Wu, Z., Xia, Z., & Xiao, J. Y. (2025) · Medicine · doi:10.1097/md.0000000000041761 · Cited by 4

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

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Panel Biomarkers Associated with Cancer Invasion and Prognostic Prediction for Head–Neck Cancer

Chen, Y., Chang, J. T., You, G.-R., Huang, C.-Y., Fan, K., & Cheng, A. (2021) · Biomarkers in Medicine · doi:10.2217/bmm-2021-0213 · Cited by 4

Gene Signatures and Cancer-Immune Phenotypes Based on m6A Regulators in Breast Cancer

Zhao, G., An, J., Pu, Q., Geng, W., Song, H., Zhao, Q., & Gao, H. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.756412 · Cited by 4

E2F Transcription Factors in Cancer, More than the Cell Cycle

Broeker, C. D., & Andrechek, E. R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820472-6.00102-x · Cited by 5

High miR‑3609 expression is associated with better prognosis in TNBC based on mining using systematic integrated public sequencing data

Ding, R., Duan, Z., Yang, M., Wang, X., Li, D., & Kan, Q. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.10976 · Cited by 4

An Immune Feature-Based, Three-Gene Scoring System for Prognostic Prediction of Head-and-Neck Squamous Cell Carcinoma

Zhang, Y., Luo, X., Yu, J., Qian, K., & Zhu, H. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2021.739182 · Cited by 4

LPAR2 correlated with different prognosis and immune cell infiltration in head and neck squamous cell carcinoma and kidney renal clear cell carcinoma

Sun, K., Chen, R., Li, J., & Luo, Z. (2022) · Hereditas · doi:10.1186/s41065-022-00229-w · Cited by 5

Systematic Analysis of Neurotransmitter Receptors in Human Breast Cancer Reveals a Strong Association With Outcome and Uncovers HTR6 as a Survival-Associated Gene Potentially Regulating the Immune Microenvironment

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Establishment and Validation of an Interferon-Stimulated Genes (ISGs) Prognostic Signature in Pan-cancer Patients: A Multicenter, Real-world Study

Zhou, Z., Zheng, Y., Mo, S., Li, S., Zheng, X., Wei, R., Fan, T. T., Chen, T., Xiao, C., Li, C., et al. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.71385 · Cited by 4

Upregulation of circ_0008812 and circ_0001583 predicts poor prognosis and promotes breast cancer proliferation

Lin, H., Long, F., Zhang, X., Wang, P., & Wang, T. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.1017036 · Cited by 4

Conventional Ameloblastoma. A Case Report with Microarray and Bioinformatic Analysis

Jurado-Castañeda, E., Ramírez-Martínez, C. M., Alonso-Moctezuma, A., Páramo-Sánchez, J. T., Rivera-Reza, D. I., Chanes‐Cuevas, O. A., Ortiz-Solís, C. L., Téliz-Meneses, M. A., Hernández-Ortega, O. R., Bolaños, M. X. V., et al. (2022) · Diagnostics · doi:10.3390/diagnostics12123190 · Cited by 4

Functional status analysis of RNH1 in bladder cancer for predicting immunotherapy response

Chen, S., Ran, J., Fan, Z., Liu, M., Wu, L. L., Li, Q., Peng, J., & Hu, Z. (2023) · Scientific Reports · doi:10.1038/s41598-023-39827-7 · Cited by 4

Synthetic lethality in human bladder cancer cells by curcumin via concurrent Aurora A inhibition and autophagy induction

Fan, Y.-W., Lu, I.-C., Hsu, M.-Y., Kuo, W., Wu, S., Lan, S., Wang, P.-Y., Chen, C.-Y., Liu, H., & Su, C. (2023) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2023.109438 · Cited by 4

Hsa-miR-194-5p and hsa-miR-195-5p are down-regulated expressed in high dysplasia HPV-positive Pap smear samples compared to normal cytology HPV-positive Pap smear samples

Dehghani, A., Khajepour, F., Dehghani, M., Razmara, E., Zangouey, M., Abadi, M. F. S., Nezhad, R. B. A., Dabiri, S., & Garshasbi, M. (2024) · BMC Infectious Diseases · doi:10.1186/s12879-023-08942-1 · Cited by 4

Network pharmacology integrated molecular docking of fucoidan against oral cancer and in vitro evaluation- A study using GEO datasets

Antonisamy, A. J., Rajendran, K., & Dhanaraj, P. (2024) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2024.2316771 · Cited by 4

Synchronous profiling of mRNA N6-methyladenosine modifications and mRNA expression in high-grade serous ovarian cancer: a pilot study

Yang, L. C., Liu, J., Jin, Y., Xing, J., Zhang, J., Chen, X., & Yu, A. (2024) · Scientific Reports · doi:10.1038/s41598-024-60975-x · Cited by 4

Functional Screenings Identify Regulatory Variants Associated with Breast Cancer Susceptibility

Ren, N., Li, Y., Xiong, Y., Li, P., Ren, Y., & Huang, Q. (2021) · Current Issues in Molecular Biology · doi:10.3390/cimb43030124 · Cited by 4

Anthrax toxin receptor 2 is a potential therapeutic target for non-small cell lung carcinoma with MET exon 14 skipping mutations

Yamaguchi, M., Hirai, S., Idogawa, M., Uchida, H., & Sakuma, Y. (2022) · Experimental Cell Research · doi:10.1016/j.yexcr.2022.113078 · Cited by 4

Comprehensive analysis of the oncogenic roles of vascular endothelial growth factors and their receptors in stomach adenocarcinoma

Li, J., & Han, T. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e17687 · Cited by 4

The role of miR-4469 as a tumor suppressor regulating inflammatory cell infiltration in colorectal cancer

Qi, L., Wang, L., Song, F., Ding, Z., & Zhang, Y. (2022) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2022.07.021 · Cited by 4

A cellular and spatial atlas of TP53 -associated tissue remodeling in lung adenocarcinomaPreprint

Zhao, W., Kepecs, B., Mahadevan, N. R., Segerstolpe, Å., Weirather, J. L., Besson, N. R., Giotti, B., Soong, B. Y., Li, C., Vigneau, S., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.06.28.546977 · Cited by 4

Cell cycle associated protein 1 associates with immune infiltration and ferroptosis in gastrointestinal cancer

Gao, Y., Wu, R.-M., Pei, Z.-J., Ke, C.-B., Zeng, D.-B., Li, X., & Zhang, Y. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e28794 · Cited by 3

Earlier or Later? A Survival Analysis of Criminal Career and Contextual Factors Associated With Intimate Partner Homicide in Canada

Chopin, J., Guay, J., Fortin, F., Paquette, S., Péloquin, O., & Chartrand, É. (2024) · The British Journal of Criminology · doi:10.1093/bjc/azae023 · Cited by 3

THG-1/TSC22D4 Promotes IL-1 Signaling through Stabilization of TRAF6 in Squamous Cell Carcinoma

Okano, Y., Suzuki, H., Watanabe, Y., Abdelaziz, M. O., Manevich, L., Kawanishi, K., Ozaki, H., Ishii, R., Matsumoto, S., Goto, N., et al. (2025) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-24-0120 · Cited by 3

Tumor innervation in cervical cancer: Prognostic insights from myelin‐associated risk signatures

Chen, G.-Q., Zheng, Z., Ji, Q., He, R., Pan, Z., Chen, Y., Zhou, Y., Wei, Z., Sun, H. X., & Feng, L. (2025) · FASEB BioAdvances · doi:10.1096/fba.2024-00190 · Cited by 3

Beyond Transposons: TIGD1 as a Pan-Cancer Biomarker and Immune Modulator

Albayrak, M. G. B., Korak, T., Akpınar, G., & Kasap, M. (2025) · Genes · doi:10.3390/genes16060674 · Cited by 3

SENP5 drives breast cancer progression through deSUMOYlation of CDK1

Cui, C., Yao, H., Jie, H., Liang, Z., Zhang, Y., Wen, X., Zhao, J., Xiong, H., Zheng, Z., & Wu, J. (2025) · Breast Cancer Research · doi:10.1186/s13058-025-02054-1 · Cited by 3

HSPB6 based on integrative multi-omics analysis can suppress colorectal cancer progression by downregulating HSPA6 expression through the JNK-JUND axis

Cao, Y., Yu, Y., Tian, T., Fu, Q., Zhao, N., Qu, C., Dong, Y., Li, S., Xu, T., Cui, B., et al. (2025) · Life Sciences · doi:10.1016/j.lfs.2025.124001 · Cited by 3

TRIM32 promotes tumor immune evasion and impedes Anti–PD-1 treatment by inducing immunosuppressive macrophages in gastric cancer

Wang, C., Zhu, X., Wang, J., Hu, Z., Xiang, P., Xu, J., Xu, J., & Cai, Q. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06330-8 · Cited by 3

Osimertinib activates a TGF-β2–dependent secretory program that drives lung adenocarcinoma progression

Ghosh, M., Wu, C., Kumar, A., Nilsson, M. B., Heymach, J. V., Zhao, W., Yu, J., Liu, X., Ding, N., Wang, S., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci198418 · Cited by 3

Super-Resolution Fluorescence Imaging Reveals the Role of CD24 Clusters in NSCLC Proliferation

Wang, J., Li, B., Li, M., Li, L., Chen, X., Wang, H., Zhang, G., Gao, J., & Tong, T. (2026) · Analytical Chemistry · doi:10.1021/acs.analchem.5c05213 · Cited by 3

Computational method for aromatase-related proteins using machine learning approach

Selvaraj, M. K., & Kaur, J. (2023) · PLoS ONE · doi:10.1371/journal.pone.0283567 · Cited by 3

STARD12/14 are diagnostic and prognostic biomarkers of lung adenocarcinoma associated with epigenetic regulation, immune infiltration and ferroptosis

Zhang, W., Hu, D., Shi, Z.-E., Wang, Q., Zhang, M., Liu, J., Ji, X.-L., & Qu, Y.-Q. (2023) · International Journal of Medical Sciences · doi:10.7150/ijms.84566 · Cited by 3

Are androgen receptor agonists a treatment option in bladder cancer?

Ieso, M. L. D., Aldoghachi, A. F., Tilley, W. D., & Dwyer, A. R. (2024) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2024.106623 · Cited by 3

Programmable Loading of a Multivalent LRPPRC Aptamer onto a Rectangular DNA Tile Inhibits the Proliferation of Lung Adenocarcinoma Cells

Zhang, X., Yang, Y., Tian, Z., Du, Z., Zhou, W., Fu, T., Zheng, L., Luo, C., Peng, R., & Tan, W. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5c02782 · Cited by 3

Pan-Cancer Analysis of G Protein-Coupled Receptors as Cancer Driver Genes and Drug Repurposing Targets

Hou, Y., Liu, Y., Pang, C., Shi, N., Huang, X., Cao, C., & Shu, C. (2025) · Journal of Chemical Information and Modeling · doi:10.1021/acs.jcim.5c00689 · Cited by 3

Prediction and Identification of GPCRs Targeting for Drug Repurposing in Osteosarcoma

Tan, M., Shangzhi, G., Ru, X., He, M., Zhao, J., & Zheng, L. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.828849 · Cited by 3

COX PROPORTIONAL HAZARD REGRESSION SURVIVAL ANALYSIS FOR TYPE 2 DIABETES MELITUS

Mahmudah, U., Surono, S., Prasetyo, P. W., Lola, M. S., & Haryati, A. E. (2022) · BAREKENG JURNAL ILMU MATEMATIKA DAN TERAPAN · doi:10.30598/barekengvol16iss1pp251-260 · Cited by 3

Prognostic value of metabolic genes in lung adenocarcinoma via integrative analyses

Hou, G., Lu, Z., Yang, Z., & Jiang, J. F. (2022) · Genomics · doi:10.1016/j.ygeno.2022.110425 · Cited by 3

Kidney Cancer Biomarker Selection Using Regularized Survival Models

Peixoto, C., Martins, M., Costa, L., & Vinga, S. (2022) · Cells · doi:10.3390/cells11152311 · Cited by 3

The expression and role of tubulin polymerization-promoting protein 3 in oral squamous cell carcinoma

Xiao, T., Lin, F., Zhou, J., & Tang, Z. (2022) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2022.105519 · Cited by 3

Pancancer Analysis of the Prognostic and Immunotherapeutic Value of Progestin and AdipoQ Receptor 4

Yang, Z., Zhu, Y., Li, Z., Pu, Z., Lin, Y. N., Deng, Y., Li, N., & Peng, F. (2022) · Computational and Mathematical Methods in Medicine · doi:10.1155/2022/2528164 · Cited by 3

Cuproptosis-related LncRNAs are correlated with immunity and predict prognosis in HNSC independent of TMB

Li, M. K., Nurzat, Y., Huang, H., Min, P., & Zhang, X. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1028044 · Cited by 3

Identify AGAP2 as prognostic biomarker in clear cell renal cell carcinoma based on bioinformatics and IHC staining

Xu, Z., Wang, Y., Xu, J., Ang, X., Ge, N., Xu, M., & Pei, C.-S. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e13543 · Cited by 3

A Comprehensive Overview of Artificial Intelligence in Healthcare

Ujager, F. S., Hamacha, S. R., & Benjamin, B. (2023) · Advances in computer and electrical engineering book series · doi:10.4018/978-1-6684-6937-8.ch016 · Cited by 3

CUL4A silencing attenuates cervical carcinogenesis and improves Cisplatin sensitivity

Atri, Y., Bharti, H., Sahani, N., Sarkar, D. P., & Nag, A. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04776-2 · Cited by 3

Post-therapeutic microRNA-146a in liquid biopsies may determine prognosis in metastatic gastrointestinal cancer patients receiving 90Y-radioembolization

Hirner-Eppeneder, H., Öcal, E., Stechele, M., Öcal, O., Gu, S., Kimm, M. A., Wildgruber, M., Salvermoser, L., Kazmierczak, P. M., Corradini, S., et al. (2023) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-023-05185-0 · Cited by 3

Cuproptosis-Related 4-Gene Risk Model for Predicting Immunotherapy Drug Response and Prognosis of Kidney Renal Clear Cell Carcinoma

Guo, J.-S., Ding, H., Wu, P., Xin, Z.-Y., Li, J., Jo, H., & Ma, Z. (2023) · Chinese Medical Sciences Journal · doi:10.24920/004223 · Cited by 3

COX2-Inhibitory and Cytotoxic Activities of Phytoconstituents of Matricaria chamomilla L.

Drif, A. I., Avula, B., Khan, I. A., & Efferth, T. (2023) · Applied Sciences · doi:10.3390/app13158935 · Cited by 3

Semaphorin4F is a potential biomarker for clinical progression and prognosis in gastric cancer.

Wang, H., Ji, X., Chen, L., Ju, L., Ma, Q., Wu, Y., & Cai, W. (2023) · PubMed Central · Cited by 3

Integrative analysis of circular RNA regulatory network in papillary thyroid carcinoma.

‍Kim, D. Y., Lee, Y., Dho, S. H., Park, H., Kim, D.-M., Lim, J. C., Kim, S., & Kim, L. K. (2023) · PubMed Central · Cited by 3

The cadherin protein CDH19 mediates cervical carcinoma progression by regulating AKT/NF-κB signaling

Yu, J., Sun, X., Yu, Y., & Cui, X. (2023) · Acta Biochimica Polonica · doi:10.18388/abp.2020_6902 · Cited by 3

Aberrated PSMA1 expression associated with clinicopathological features and prognosis in oral squamous cell carcinoma

Rukmini, D., Kannan, B., Pandi, C., Pandi, A., Prasad, P., Jayaseelan, V. P., & Arumugam, P. (2024) · Odontology · doi:10.1007/s10266-023-00883-0 · Cited by 3

Dickkopf-1 is an immune infiltration-related prognostic biomarker of head and neck squamous cell carcinoma

Zhao, C., Liu, L., He, Q., Li, Y., Feng, J., Chen, Y., Li, Y., Xu, X., Zhu, S., Ye, Y., et al. (2024) · Aging · doi:10.18632/aging.205563 · Cited by 3

Identification of potential targetable genes in papillary, follicular, and anaplastic thyroid carcinoma using bioinformatics analysis

Agarwal, S., Gupta, S., & Raj, R. (2024) · Endocrine · doi:10.1007/s12020-024-03836-x · Cited by 3

The concomitant use of the renin–angiotensin system inhibitors and survival outcomes of patients with pancreatic adenocarcinoma: an analysis from a tertiary center

Tseng, K.-Y., Hsu, C., Shih, Y., Lin, H., Li, Y.-C., Teng, C. J., & Chou, C. (2024) · Therapeutic Advances in Medical Oncology · doi:10.1177/17588359241247019 · Cited by 3

TESMIN is a Prognostic Biomarker Associated with Immunosuppression and Activated Cell Cycle in Lung Adenocarcinoma

Yao, Z., Song, P., Dong, Y., Wu, Z., Kong, W., & Jiao, W. (2024) · Current Medicinal Chemistry · doi:10.2174/0109298673315434240826100918 · Cited by 3

Aberrant promoter methylation of CTHRC1 gene and its clinicopathological characteristics in head and neck cancer

Kumar, A., Kannan, B., Girija, A. S. S., Jayaseelan, V. P., & Arumugam, P. (2025) · International Journal of Oral and Maxillofacial Surgery · doi:10.1016/j.ijom.2025.01.005 · Cited by 3

Lipid metabolism associated PLPP4 gene drives oncogenic and adipogenic potential in breast cancer cells

Soni, S., Makwana, S. H., Bansal, S., Kumari, M., & Mandal, C. C. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2025.159609 · Cited by 3

Identifying and validating PLAU as a potential prognostic biomarker for PDAC

An, P., Wang, J., & Fan, R. (2025) · Scientific Reports · doi:10.1038/s41598-025-97629-5 · Cited by 3

Semi-automated high content analysis of pollen performance using tubetracker

Ouonkap, S. V. Y., Oseguera, Y., Okihiro, B., & Johnson, M. A. (2025) · Plant Reproduction · doi:10.1007/s00497-025-00526-0 · Cited by 3

Study on the Potential Molecular Mechanism of Xihuang Pill in the Treatment of Pancreatic Cancer Based on Network Pharmacology and Bioinformatics

Wang, J., Zhang, Y., Wang, Q., Wang, L., & Zhang, P. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/4651432 · Cited by 3

Aberrant expression of the esophageal carcinoma related gene 4 as a prognostic signature for hepatocellular carcinoma

You, Y., Hu, S., Deng, Y., & Hu, F. (2022) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2022.101891 · Cited by 3

Expression of Novel Kinase MAP3K19 in Various Cancers and Survival Correlations

Nguyen, K., Yousefi, H., Cheng, T., Magrath, J. W., Hartono, A. B., Alzoubi, M. S., Hebert, K. L., Brock, C. K., Wright, M. K., Byrne, C. E., et al. (2022) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2706196 · Cited by 3

Sensory nerves enhance triple-negative breast cancer migration and metastasis via the axon guidance molecule PlexinB3Preprint

Le, T. T., Payne, S. L., Buckwald, M. N., Hayes, L. A., Burge, C. B., & Oudin, M. J. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.07.471585 · Cited by 3

Over-expression of CDK1 in human endometrial cancer.Preprint

Mamoor, S. (2021) · doi:10.31219/osf.io/fbqdt · Cited by 3

A multi-omic dissection of super-enhancer driven oncogenic gene expression programs in ovarian cancerPreprint

Kelly, M. R., Wiśniewska, K., Regner, M. J., Lewis, M. W., Perreault, A. A., Davis, E. S., Phanstiel, D. H., Parker, J. S., & Franco, H. L. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.08.487699 · Cited by 3

Persistent impact of COVID-19 pandemic on mobility behavior of paratransit users, montreal case study

Garnier, C., Trépanier, M., & Morency, C. (2024) · Journal of Transport & Health · doi:10.1016/j.jth.2024.101777 · Cited by 2

KIS, a target of SOX4, regulates the ID1-mediated enhancement of β-catenin to facilitate lung adenocarcinoma cell proliferation and metastasis

Chang, J., Zhang, M., Lou, L.-L., Chu, H., & Wang, H. (2024) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-024-05853-9 · Cited by 2

Prognostic importance of splicing-triggered aberrations of protein complex interfaces in cancer

Newaz, K., Schaefers, C., Weisel, K. C., Baumbach, J., & Frishman, D. (2024) · NAR Genomics and Bioinformatics · doi:10.1093/nargab/lqae133 · Cited by 2

Rhomboid Domain Containing 2 (RHBDD2) is Upregulated and Responds to Cisplatin-Induced DNA Damage in Esophageal Cancer

Ding, Y., Zhou, L., He, X., Li, L., & Wang, X. (2025) · Biochemical Genetics · doi:10.1007/s10528-025-11118-y · Cited by 2

Surgery/anesthesia may cause monocytes to promote tumor development

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EP300 promotes hepatocellular carcinoma proliferation, migration and in vivo tumorigenicity revealed by integrated experimental and bioinformatic analyses

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