The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Pancancer survival analysis of cancer hallmark genes
Open accessAbstract
Cancer hallmark genes are responsible for the most essential phenotypic characteristics of malignant transformation and progression. In this study, our aim was to estimate the prognostic effect of the established cancer hallmark genes in multiple distinct cancer types. RNA-seq HTSeq counts and survival data from 26 different tumor types were acquired from the TCGA repository. DESeq was used for normalization. Correlations between gene expression and survival were computed using the Cox proportional hazards regression and by plotting Kaplan–Meier survival plots. The false discovery rate was calculated to correct for multiple hypothesis testing. Signatures based on genes involved in genome instability and invasion reached significance in most individual cancer types. Thyroid and glioblastoma were independent of hallmark genes (61 and 54 genes significant, respectively), while renal clear cell cancer and low grade gliomas harbored the most prognostic changes (403 and 419 genes significant, respectively). The eight genes with the highest significance included BRCA1 (genome instability, HR 4.26, p < 1E−16), RUNX1 (sustaining proliferative signaling, HR 2.96, p = 3.1E−10) and SERPINE1 (inducing angiogenesis, HR 3.36, p = 1.5E−12) in low grade glioma, CDK1 (cell death resistance, HR = 5.67, p = 2.1E−10) in kidney papillary carcinoma, E2F1 (tumor suppressor, HR 0.38, p = 2.4E−05) and EREG (enabling replicative immortality, HR 3.23, p = 2.1E−07) in cervical cancer, FBP1 (deregulation of cellular energetics, HR 0.45, p = 2.8E−07) in kidney renal clear cell carcinoma and MYC (invasion and metastasis, HR 1.81, p = 5.8E−05) in bladder cancer. We observed unexpected heterogeneity and tissue specificity when correlating cancer hallmark genes and survival. These results will help to prioritize future targeted therapy development in different types of solid tumors.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Kaplan–Meier analysis using public breast cancer meta-analysis database11,30 reveals that TNBC patients with higher hypoxia gene signature are associated with worse disease outcomes, including both overall survival (OS) and distant metastasis-free survival (DMFS), compared to those with lower expression of hypoxia gene signature (Fig. 1h).”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625
Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219
Differential expression analysis for sequence count data
Anders, S., & Huber, W. (2010) · Genome Biology · doi:10.1186/gb-2010-11-10-r106 · Cited by 15,581
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
METABRIC Group, Curtis, C., Shah, S. P., Chin, S.-F., Turashvili, G., Rueda, O. M., Dunning, M. J., Speed, D., Lynch, A. G., Samarajiwa, S., et al. (2012) · Nature · doi:10.1038/nature10983 · Cited by 6,097
Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer
Romond, E. H., Perez, E. A., Bryant, J., Suman, V. J., Geyer, C. E., Davidson, N. E., Tan-Chiu, E., Martino, S., Paik, S., Kaufman, P. A., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa052122 · Cited by 5,438
Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer
Piccart-Gebhart, M. J., Procter, M., Leyland-Jones, B., Goldhirsch, A., Untch, M., Smith, I., Gianni, L., Baselga, J., Bell, R., Jackisch, C., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa052306 · Cited by 5,084
Tamoxifen for early breast cancer: an overview of the randomised trials
Abe, O., Bartholomeus, S., & Piccart, M. J. (1998) · The Lancet · doi:10.1016/s0140-6736(97)11423-4 · Cited by 4,180
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
Wang, Y., Klijn, J. G. M., Zhang, Y., Sieuwerts, A. M., Look, M. P., Yang, F., Talantov, D., Timmermans, M. A. M., Gelder, M. E. M., Yu, J. X., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17947-1 · Cited by 2,831
Focan, C., Steinberg, S. M., Blichert-Toft, M., Forbes, J., Collins, R. D., Anderson, S., Margreiter, R., Harwood, C. S., Andersen, K., Beighton, G., et al. (1998) · PubMed · Cited by 2,146
Cited by
Sorted by citations
Items 701–800 of 1,000
Kane, L. E., Flood, B., Manils, J., McSkeane, D. E., Smith, A. P., Tosetto, M., AlAlawi, F., Fay, J., Kay, E. W., Dunne, C., et al. (2024) · Gastro Hep Advances · doi:10.1016/j.gastha.2024.09.007 · Cited by 2
Identification of Cuproptosis-Associated Prognostic Gene Expression Signatures from 20 Tumor Types
Ooko, E., Ali, N. T., & Efferth, T. (2024) · Biology · doi:10.3390/biology13100793 · Cited by 3
A pan-cancer analysis of the oncogenic function of HMGB1 in human tumors
Yang, H.-M., Zhao, X.-N., Li, X., Wang, X., Pu, Y., Wei, D., & Li, Z. (2024) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2024.101851 · Cited by 2
Multi-omics uncovers the potential functions of transcription factor Dp-1 in human digestive cancers
Song, Y., Wang, X., & Ma, R. (2024) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2024.107240 · Cited by 2
Acharya, R., Deb, P. K., & Pattanayak, S. P. (2025) · Current Medicinal Chemistry · doi:10.2174/0109298673356682241205044326 · Cited by 2
Cheng, Z., Luo, X., Liu, W., Lu, X., Chang, H., Wang, Y., Zheng, W., Yan, X., & Huang, Y. (2025) · Cell & Bioscience · doi:10.1186/s13578-025-01361-6 · Cited by 2
The transcription factor RIP140 regulates interferon γ signaling in breast cancer
Jalaguier, S., Kuehn, A., Petitpas, C., Dulom, A., Jacquemont, R., Assi, C., Doisneau-Sixou, S. F., Jeschke, U., Colinge, J., & Cavaillès, V. (2025) · International Journal of Cancer · doi:10.1002/ijc.35405 · Cited by 2
Eldeen, M. A., Mostafa, A., Mamdouh, F., Abdulsahib, W. K., Alshaya, D. S., Fayad, E., Otifi, H. M., Hassan, H. M., Alshehri, M., Althobaiti, A., et al. (2025) · Discover Oncology · doi:10.1007/s12672-025-03631-8 · Cited by 2
Current Update on the Risk Factor Modification and Excercise Following Coronary Artery Disease
Rahmianti, N. D., Yusrizal, T., & Farabi, M. J. A. (2020) · Biomolecular and Health Science Journal · doi:10.20473/bhsj.v3i1.17994 · Cited by 2
Yang, Y., Li, J., Tang, M., Nie, B., & Huang, W. (2022) · Cancer Management and Research · doi:10.2147/cmar.s364346 · Cited by 2
Lin, Z., Huang, X., Ji, X., Tian, N., Gan, Y., & Ke, L. (2022) · Scientific Reports · doi:10.1038/s41598-022-13159-4 · Cited by 2
Rabe, P., Gehmlich, M., Peters, A., Krumbholz, P., Nordström, A., & Stäubert, C. (2022) · Discover Oncology · doi:10.1007/s12672-022-00503-3 · Cited by 2
Ge, L., Sun, Q., Xia, L., & Xu, X. (2022) · Medicine · doi:10.1097/md.0000000000029802 · Cited by 2
Wang, Y., Wang, Z., Li, K., Xiang, W., Chen, B., Jin, L., & Hao, K. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.874667 · Cited by 2
Validation of the Anticolitis Efficacy of the Jian-Wei-Yu-Yang Formula
Yan, J., Tang, Y., Yu, W., Jiang, L., Liu, C., Li, Q., Zhang, Z., Shao, C., Zheng, Y., Liu, X., et al. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/9110704 · Cited by 2
Liu, Y., Wang, K., Zhou, Y., Zhuang, X., Shao, S., Qiao, F., Wang, X., Zou, X., & Qiao, T. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1039145 · Cited by 2
Microarray and bioinformatic analysis of conventional ameloblastoma: an observational analysis
Jacinto‐Alemán, L. F., Portilla‐Robertson, J., Leyva-Huerta, E. R., Ramírez‐Jarquín, J. O., & Villanueva‐Sánchez, F. G. (2022) · Journal of Applied Oral Science · doi:10.1590/1678-7757-2022-0308 · Cited by 2
Fujiwara, S., Saiki, Y., Fukushige, S., Yamanaka, M., Ishida, M., Motoi, F., Unno, M., & Horii, A. (2023) · Surgery Today · doi:10.1007/s00595-023-02655-3 · Cited by 2
The prognostic significance and potential mechanism of DBF4 zinc finger in hepatocellular carcinoma
Wu, Z., Zhang, L., Li, X., Liu, L., Kuang, T., Qiu, Z., Deng, W., & Wang, W. (2024) · Scientific Reports · doi:10.1038/s41598-024-60342-w · Cited by 2
Khaboushan, A. S., Salimian, S. N., Mehraban, S., Bahramy, A., Zafari, N., Kajbafzadeh, A. M., Johnson, J. R., & Zolbin, M. M. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35202 · Cited by 2
A Signature of Three MicroRNAs is a Potential Diagnostic Biomarker for GlioblastomaPreprint
Yazdi, A. H., Zarrinpour, V., Moslemi, E., & Forghanifard, M. M. (2021) · Research Square · doi:10.21203/rs.3.rs-1048138/v1 · Cited by 2
Liu, L., & Liu, Y. (2022) · Research Square · doi:10.21203/rs.3.rs-1249485/v1 · Cited by 2
Over-expression of epithelial cell transforming 2 in human endometrial cancer.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/v4aqy · Cited by 2
Differential expression of ECT2 in colorectal cancer.Preprint
Mamoor, S. (2023) · doi:10.31219/osf.io/h98mw · Cited by 2
Differential expression of SLC4A4 in colorectal cancer.Preprint
Mamoor, S. (2023) · doi:10.31219/osf.io/8qrfu · Cited by 2
Feng, Z., Yong, L. I. A. N., & Yixuan, W. A. N. G. (2023) · Research Square · doi:10.21203/rs.3.rs-3201798/v1 · Cited by 2
Signalling-state dependent drug-tolerance in head and neck squamous cell carcinomaPreprint
Karjosukarso, D. W., Dini, A., Wingens, L., Liu, R., Joosten, L. A. B., Bussink, J., & Mulder, K. W. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.05.570063 · Cited by 2
Family-Wide Photoproximity Profiling of Integrin Protein Social Networks in CancerPreprint
Carlos, A. J., Yang, D., Thomas, D. M., Huang, S., Harter, K. I., & Moellering, R. E. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.18.613588 · Cited by 3
Koo, B., Lee, D., Lee, S., Sung, I., Kim, S., & Lee, S. (2022) · Cancers · doi:10.3390/cancers14174120 · Cited by 1
Elevated expression of endocan in the development of cervical squamous neoplasia of the uterus
Sato, M., Inoue, A., Takasawa, A., Takasawa, K., Kyuno, D., Ono, Y., Magara, K., & Osanai, M. (2023) · Medical Molecular Morphology · doi:10.1007/s00795-023-00353-0 · Cited by 1
Hailati, S., Talihati, Z., Abudurousuli, K., Han, M., Nuer, M., Khan, N., Maihemuti, N., Simayi, J., Dilimulati, D., Nueraihemaiti, N., et al. (2023) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-023-04797-w · Cited by 1
Multi-Omics Analysis of NFE2L2-Altered TCGA-Cervical Squamous Cell Carcinoma Patients
Ramisetti, S. V., & Namani, A. (2023) · doi:10.3390/iecc2023-14223 · Cited by 1
Kotnala, S., Dhasmana, A., Dhasmana, S., Haque, S., Yallapu, M. M., Tripathi, M. K., Jaggi, M., & Chauhan, S. C. (2023) · Journal of Environmental Pathology Toxicology and Oncology · doi:10.1615/jenvironpatholtoxicoloncol.2023048056 · Cited by 1
Wang, M., Liu, L., Li, X., Jiang, W., Xiao, J., Hao, Q., Wang, J., Reddy, A. V., Talbot, A., Ikuta, S., et al. (2024) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo-24-147 · Cited by 1
Wang, X., Liu, H., Wu, G., Lü, Y., & Cui, Y. (2024) · Scientific Reports · doi:10.1038/s41598-024-68130-2 · Cited by 1
A Comprehensive Analysis of the Role of PAX9 in Head and Neck Squamous Cell Carcinoma
Zeng, L., Yun, W., & Luo, W. (2025) · Current Molecular Medicine · doi:10.2174/0115665240328109241205084841 · Cited by 1
Sankar, D., Pandi, A., Sinduja, P., Jayaseelan, V. P., & Arumugam, P. (2025) · Journal of Oral and Maxillofacial Surgery Medicine and Pathology · doi:10.1016/j.ajoms.2025.04.014 · Cited by 1
Integrated pan-cancer analysis revealed therapeutic targets in the ABC transporter protein family
Masood, M. B. E., Shafique, I., Rafique, M. I., Iman, A., Abbasi, A., Rafiq, M., & Habib, U. (2025) · PLoS ONE · doi:10.1371/journal.pone.0308585 · Cited by 1
OCIAD2 Promotes Cancer Progression via Metabolic Reprogramming in Lung Adenocarcinoma
Huang, Y.-H., Chang, W., Shen, C.-Y., Su, K., Chang, G., Chen, J., Lee, W.-Y., Chen, Y., & Yu, S. (2025) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5c00273 · Cited by 2
Gopalakrishnan, K., Pandi, C., Jayaseelan, V. P., & Arumugam, P. (2025) · Journal of Oral Biology and Craniofacial Research · doi:10.1016/j.jobcr.2025.08.024 · Cited by 1
Yuan, Y., Sun, D., Yang, M., Xia, Y., Yuan, C., & Wang, X. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1658705 · Cited by 1
Choochuen, P., Sangkhathat, S., Chiangjong, W., Attawettayanon, W., Leetanaporn, K., Surachat, K., Sukpan, P., Kaewrattana, W., Senkhum, O., Khongcharoen, N., et al. (2025) · Biomedicines · doi:10.3390/biomedicines13123020 · Cited by 1
Rahman, K., Malik, A., Iqbal, F., & Tariq, U. (2023) · Specialty journal of Pharmacognosy Phytochemistry and Biotechnology · doi:10.51847/6epwrws46c · Cited by 1
High expression of TRMT112 is associated with the development of oral squamous cell carcinoma
Pandi, A., Rajendhiran, P., Jayaseelan, V. P., & Arumugam, P. (2026) · Journal of Oral Biology and Craniofacial Research · doi:10.1016/j.jobcr.2025.12.014 · Cited by 1
UBR5, a potential diagnostic and prognostic biomarker induces osteosarcoma progression
Li, M., Liang, J., Jiang, X., Zheng, M., Liu, Y., Jiang, H., Long, H., Wong, V. K. W., & Fu, J. (2026) · Pathology - Research and Practice · doi:10.1016/j.prp.2026.156361 · Cited by 1
Mondal, A., Paul, D., Mondal, T., & Mondal, A. (2026) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2026.111563 · Cited by 1
Chang, Y.-C., Huang, W.-L., Su, W., Leung, E. Y., Cheng, F., & Cheung, C. H. A. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s588571 · Cited by 1
Elevated GCN2 levels in cancer cells confer protection from mitotic stress and faster cell movement
Stonyte, V., Fjeldbo, C., Langiu, M., Joy-Immediato, M., Swaminathan, P., Humagain, P. S., Valencia-Pesqueira, L. M., Lindbergsengen, L., Campsteijn, C., Lyng, H., et al. (2026) · Cellular Oncology · doi:10.1007/s13402-026-01214-5 · Cited by 1
Kaiso modulates androgen receptor expression in triple-negative breast cancer
Fairbairn, S. A., Kim, K., Cowan, R. W., Lessey, L. R., Fanaian, M., Adan, H., Golamari, S., Rattan, R., & Daniel, J. M. (2026) · Breast Cancer Research · doi:10.1186/s13058-026-02299-4 · Cited by 1
Du, S., Tang, K., Li, J., Hu, X., & Zhan, P. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6c01234 · Cited by 1
Lee, C., Pan, H.-J., Lee, Y., Nguyen, H. D., Ni, Y.-C., Yee, K. X., Nguyen, M. T., Wu, Y.-F., & Lee, K. (2026) · Genes · doi:10.3390/genes17080922 · Cited by 1
Zhong, X., Liao, H., Hu, S., Luo, K., & Zhu, H. (2021) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2021.101759 · Cited by 1
Emerging Trends in Bioinformatics for Breast Cancer Molecular Research
Mandape, S. N. (2022) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9781681089522112010007 · Cited by 1
Zhu, M., Liao, G., Wang, Y., Mo, J., Yi, D., Zhang, Y., & Xian, L. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.952528 · Cited by 1
Goswami, A. M. (2022) · Human Gene · doi:10.1016/j.humgen.2022.201119 · Cited by 1
Shaik, S. M., Campbell, H., & Williams, C. C. (2022) · BioMedInformatics · doi:10.3390/biomedinformatics2040045 · Cited by 1
Qiu, S., Zhang, Y., & Hu, Y. (2022) · IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm55620.2022.9995673 · Cited by 1
Liu, X., Zhang, Q., Mao, T., Min, C., Guo, J., Zhang, C., Tian, Z., & Li, X. (2023) · Gastroenterology & Endoscopy · doi:10.1016/j.gande.2022.11.006 · Cited by 1
Is HOXA5 a Novel Prognostic Biomarker for Uterine Corpus Endometrioid Adenocarcinoma?
Song, C., Kim, K. B., Lee, G. S., Shin, S., & Kim, B. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914758 · Cited by 1
Challa, D., Pandi, C., Kannan, B., Priyadharsini, V. J., & Arumugam, P. (2023) · Cureus · doi:10.7759/cureus.50995 · Cited by 1
Prognostic value and immune regulatory role of dynamin 1-like in lung adenocarcinoma
Song, W., Wu, X., Wang, S., Barr, M. P., Rodríguez, M. F., Oh, I., Wu, Y., & Ding, L. (2023) · Translational Lung Cancer Research · doi:10.21037/tlcr-23-685 · Cited by 1
Seo, J., Seok, J., & Kim, Y. (2024) · Healthcare · doi:10.3390/healthcare12090939 · Cited by 1
Liu, Y., Hou, J., Zhao, Y., Zhou, J.-S., Bai, S., & Ding, Y. (2024) · The FASEB Journal · doi:10.1096/fj.202302386rr · Cited by 1
Shojo, K., Tanaka, N., Murakami, T., Anno, T., Teranishi, Y., Takamatsu, K., Mikami, S., Imamura, T., Matsumoto, K., & Oya, M. (2024) · Laboratory Investigation · doi:10.1016/j.labinv.2024.102131 · Cited by 2
Chang, H., Ryu, S., Choi, I., Kwon, A. E., & Kim, J. (2024) · Healthcare · doi:10.3390/healthcare12191982 · Cited by 1
Disentangled and reassociated deep representation for dynamic survival analysis with competing risks
Cui, C., Tang, Y., & Zhang, W. (2025) · Knowledge-Based Systems · doi:10.1016/j.knosys.2025.113295 · Cited by 1
Kato, M., Nishino, J., Nagai, M., Rokutan, H., Narushima, D., Ono, H., Hasegawa, T., Imoto, S., Matsui, S., Tsunoda, T., et al. (2025) · Human Genomics · doi:10.1186/s40246-025-00744-7 · Cited by 1
Xie, Y., Fu, R., Zheng, X. W., & Li, G. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152342 · Cited by 1
Bhatia, A., Upadhyay, A. K., & Sharma, S. (2025) · Nucleosides Nucleotides & Nucleic Acids · doi:10.1080/15257770.2025.2535749 · Cited by 1
Zhao, C., Zhang, J., Ma, J., Zhang, N., & Chen, W. (2021) · Translational Cancer Research · doi:10.21037/tcr-21-294 · Cited by 1
Li, C.-X., & Dan, L. (2021) · Future Oncology · doi:10.2217/fon-2021-0275 · Cited by 1
Lin, D., Fu, R., Xi, E., & Bai, Y. (2021) · IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm52615.2021.9669275 · Cited by 1
Fathoni, M. I. A., Gunardi, G., Adi-Kusumo, F., Hutajulu, S. H., & Purwanto, I. (2022) · International Journal of Statistics in Medical Research · doi:10.6000/1929-6029.2022.11.13 · Cited by 1
Lin, J., Nong, D., Wang, W. T., Guo, X., Li, C., Li, B., Wang, H., Chen, Z., Li, X., Huang, G., et al. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.967378 · Cited by 1
Fatty Acid Metabolism as a Potential Therapeutic Target in Thyroid CarcinomaPreprint
Lu, J., Zhang, Y., Sun, M., Ding, C., Zhang, L., Kong, Y., Meng, C. A. I., Miccoli, P., Ma, C., & Yue, X. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3861577 · Cited by 1
RNF24 is a Novel Biomarker of Prognosis and Immunological Cell Infiltration in CancersPreprint
Yu, B., & Ma, M. (2021) · Research Square · doi:10.21203/rs.3.rs-906870/v1 · Cited by 1
Bioinformatics Analysis of ISLR in Pan-Cancer and its Correlation with Tumor ImmunityPreprint
Zhang, C., Long, Z., Yan, C., Jalloh, M. S., Fang, Y., Li, B., Sun, B., Shao, W., Sun, G., Fu, Y., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-970091/v1 · Cited by 1
BACH2 expression associates with survival in triple negative breast cancer.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/7e52n · Cited by 1
Over-expression of CDK5 in human endometrial cancer.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/htepu · Cited by 1
Role of miR-99a-5p in breast cancer: Translating molecular findings into clinical tools
Garrido‐Cano, I. (2021) · doi:10.4995/thesis/10251/180358 · Cited by 1
Hao, J., Chen, K., Zhang, J., Wu, D., Cao, W., Zou, J., Shang, G., Yang, J. Y. H., Wong‐Lin, K., Sun, H., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1297929/v1 · Cited by 1
Over-expression of BUB1 mitotic checkpoint serine/threonine kinase B in human endometrial cancer.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/une7s · Cited by 1
Analysis of gene expression patterns in triple negative breast cancer II: TNBC molecular subtype.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/hu5wg · Cited by 1
NSUN6, a Gene Related With m5c Methylation, May Serve as a Biomarker for Pan-cancerPreprint
Ma, B., & Wang, P. (2022) · Research Square · doi:10.21203/rs.3.rs-1352812/v1 · Cited by 1
Analysis of gene expression patterns in triple negative breast cancer: MERTK and WHSC1L1.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/7c9pu · Cited by 1
Over-expression of thymidine kinase 1 in human endometrial cancer.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/7bwsn · Cited by 1
Over-expression of centromere protein F in human endometrial cancer.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/dwyhv · Cited by 1
Over-expression of propionyl-CoA carboxylase beta subunit in human endometrial cancer.Preprint
Mamoor, S. (2021) · doi:10.31219/osf.io/qmg4c · Cited by 1
Feng, W., Wang, G., Zhang, X., Cheng, S., Song, X., Zhang, P., & Wang, J. (2022) · Research Square · doi:10.21203/rs.3.rs-1704715/v1 · Cited by 1
Aghajanzadeh, T., Talkhabi, M., Zali, M. R., Hatami, B., & Baghaei, K. (2022) · Research Square · doi:10.21203/rs.3.rs-1679515/v1 · Cited by 1
Kenneth, M. J., & Haque, F. K. M. (2022) · Research Square · doi:10.21203/rs.3.rs-1737439/v1 · Cited by 1
Yates, C. C., Angajala, A., Muhammad, A. I., Raymond, H., Ahmed, S. M., Haleema, S., Haque, M., Wang, H., Martini, R. N., Karanam, B., et al. (2022) · Preprints.org · doi:10.20944/preprints202207.0409.v1 · Cited by 1
Smith, R. J., Diba, L. Z., Srinivasan, A., Zollo, R. A., Ossevoort, T., He, Q., Colligan, S. H., Dolan, M., Vedire, Y., Sultana, T., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.09.16.508318 · Cited by 1
Yang, M., Shen, H. M., Flodby, P., Koss, M. D., Bassiouni, R., Liu, Y., Jashashvili, T., Stueve, T. R., Mullen, D. J., Ryan, A. L., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.29.514334 · Cited by 1
Insilico-based identification of survival-associated lncRNAs, mRNAs and, miRNAs in breast cancerPreprint
Sadeghi, M., Cava, C., Mousavi, P., & Sabetian, S. (2022) · Research Square · doi:10.21203/rs.3.rs-2413405/v1 · Cited by 1
Differential expression of CEACAM1 in pancreatic cancer.Preprint
Mamoor, S. (2023) · doi:10.31219/osf.io/6s7v9 · Cited by 1
Differential expression of ABCA8 in colorectal cancer.Preprint
Mamoor, S. (2023) · doi:10.31219/osf.io/yhtwg · Cited by 1
Differential expression of KPNA2 in colorectal cancer.Preprint
Mamoor, S. (2023) · doi:10.31219/osf.io/zvjfa · Cited by 1
Differential expression of GUCA2A in colorectal cancer.Preprint
Mamoor, S. (2023) · doi:10.31219/osf.io/yrz2m · Cited by 1
Differential expression of TMEM206 in colorectal cancer.Preprint
Mamoor, S. (2023) · doi:10.31219/osf.io/hmesx · Cited by 1
Metadata
- Authors
- Nagy, Á., Munkácsy, G., & Győrffy, B.
- Affiliations
- Semmelweis University (HU)
- Corresponding author
- Győrffy, Balázs
- Venue
- Scientific Reports
- Published
- 2021-03-15
- Volume
- 11
- Issue
- 1
- Pages
- 6047-6047
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC7961001
- OpenAlex
- W3139511935
- Cited by
- 1,381
- References
- 40
- Citations by year
- 2026: 38 · 2025: 84 · 2024: 145 · 2023: 504 · 2022: 311 · 2021: 298
- FWCI
- 101.01
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Semmelweis Egyetem
- Innovációs és Technológiai Minisztérium (ÚNKP-19-3, 2018-2.1.17-TET-KR-00001)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gene expression and cancer classification
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Breast Cancer Treatment Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer Genomics and Diagnostics
- Keywords
- prognostic gene signature, survival analysis, genomic instability, invasion and metastasis, replicative immortality, cell death resistance, angiogenesis, tumor suppressor, BRCA1, RUNX1, SERPINE1, CDK1, E2F1, epiregulin, c-Myc, clear cell renal cell carcinoma, low-grade glioma, cervical cancer, bladder cancer, thyroid cancer, glioblastoma, tissue specificity, targeted therapy
- MeSH terms
- RNA-Seq, Humans, Neoplasms, Biomarkers, Tumor, Survival Rate, Disease-Free Survival, Databases, Nucleic Acid, Kaplan-Meier Estimate
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
