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Microbial regulation of organismal energy homeostasis
Open accessAbstract
The gut microbiome has emerged as a key regulator of host metabolism. Here we review the various mechanisms through which the gut microbiome influences the energy metabolism of its host, highlighting the complex interactions between gut microbes, their metabolites and host cells. Among the most important bacterial metabolites are short-chain fatty acids, which serve as a direct energy source for host cells, stimulate the production of gut hormones and act in the brain to regulate food intake. Other microbial metabolites affect systemic energy expenditure by influencing thermogenesis and adipose tissue browning. Both direct and indirect mechanisms of action are known for specific metabolites, such as bile acids, branched chain amino acids, indole propionic acid and endocannabinoids. We also discuss the roles of specific bacteria in the production of specific metabolites and explore how external factors, such as antibiotics and exercise, affect the microbiome and thereby energy homeostasis. Collectively, we present a large body of evidence supporting the concept that gut microbiota-based therapies can be used to modulate host metabolism, and we expect to see such approaches moving from bench to bedside in the near future.
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“Furthermore, gut microbiota has been described in the past two decades as a very important player in the regulation of whole‐body energy homeostasis, in response to diverse stimuli such as cold 165, 166, nutrition 167, 168, or fasting/feeding cycles 168, 169, 170, through the production of mediators such as short chain fatty acids (SCFAs) and secondary BAs 167, 169.”
From Inter‐organ communication: a gatekeeper for metabolic health (2019) · cites this paper as [169]
Citations
Cites
An obesity-associated gut microbiome with increased capacity for energy harvest
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444
A human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624
A core gut microbiome in obese and lean twins
Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, B. A., Affourtit, J. P., et al. (2009) · Nature · doi:10.1038/nature07540 · Cited by 7,823
The gut microbiota as an environmental factor that regulates fat storage
Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407076101 · Cited by 6,245
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
Wang, Z., Klipfell, E., Bennett, B. J., Koeth, R., Levison, B. S., DuGar, B., Feldstein, A. E., Britt, E. B., Fu, X., Chung, Y.-M., et al. (2011) · Nature · doi:10.1038/nature09922 · Cited by 5,597
De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., Collini, S., Pieraccini, G., & Lionetti, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005963107 · Cited by 5,579
den Besten, G., van Eunen, K., Groen, A. K., Venema, K., Reijngoud, D.-J., & Bakker, B. M. (2013) · Journal of Lipid Research · doi:10.1194/jlr.r036012 · Cited by 5,048
Cani, P. D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A. M., Delzenne, N. M., & Burcelin, R. (2008) · Diabetes · doi:10.2337/db07-1403 · Cited by 4,819
Self-citationRichness of human gut microbiome correlates with metabolic markers
Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature · doi:10.1038/nature12506 · Cited by 4,662
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
Everard, A., Belzer, C., Geurts, L., Ouwerkerk, J. P., Druart, C., Bindels, L. B., Guiot, Y., Derrien, M., Muccioli, G. G., Delzenne, N. M., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219451110 · Cited by 4,511
Self-citation
Cited by
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Items 201–300 of 602
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Sun, X. L., Pan, C. Q., & Xing, H. (2021) · Hepatology International · doi:10.1007/s12072-021-10230-6 · Cited by 26
Georgiou, K. E., Belev, N. A., Koutouratsas, T., Katifelis, H., & Gazouli, M. (2022) · World Journal of Gastrointestinal Pathophysiology · doi:10.4291/wjgp.v13.i3.59 · Cited by 27
Procházková, N., Venlet, N. V., Hansen, M. L., Lieberoth, C. B., Dragsted, L. O., Bahl, M. I., Licht, T. R., Kleerebezem, M., Lauritzen, L., & Roager, H. M. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1187165 · Cited by 26
Gut Microbiota and Adipose Tissue Microenvironment Interactions in Obesity
Wang, C., Yi, Z., Ye, J., Shen, Z., Yang, F., & Zhu, S. (2023) · Metabolites · doi:10.3390/metabo13070821 · Cited by 23
Zapata, J. L., Gallardo, A., Romero, C., Valenzuela, R., Garcia-Diaz, D., Duarte-Silva, L., Bustamante, A., Gasaly, N., Gotteland, M., & Echeverría, F. (2021) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2021.102388 · Cited by 26
Gan, Q., Ye, W., Zhao, X., Teng, Y., Mei, S., Long, Y., Ma, J., Rehemutula, R., Zhang, X., Zeng, F., et al. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.113371 · Cited by 25
Deng, Y., Zhao, L., Huang, X., Zeng, Y., Xiong, Z., & Zuo, M. (2022) · Nutrition · doi:10.1016/j.nut.2022.111829 · Cited by 27
Multi-omics insights into the mechanisms of muscle damage induced by molybdenum exposure in goats
Zhou, X., & Shen, X. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.118373 · Cited by 24
Zhang, C., Zhang, C., Wang, Y., Du, M., Zhang, G., & Lee, Y. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.694357 · Cited by 24
Donabedian, P. L., Dawson, E. A., Li, Q., & Chen, J. (2021) · Ophthalmic Research · doi:10.1159/000519457 · Cited by 24
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Huwart, S. J. P., d’Oplinter, A. D. W., Rastelli, M., Hul, M. V., de Vos, W. M., Luquet, S. H., Cani, P. D., & Everard, A. (2022) · Cells · doi:10.3390/cells11162534 · Cited by 24
Self-citationChen, S., Ye, W., Clements, K. D., Zan, Z., Zhao, W., Zou, H., Wang, G., & Wu, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010673 · Cited by 24
d’Oplinter, A. D. W., Verce, M., Huwart, S. J. P., Lessard‐Lord, J., Depommier, C., Hul, M. V., Desjardins, Y., Cani, P. D., & Everard, A. (2023) · Microbiome · doi:10.1186/s40168-023-01526-w · Cited by 25
Self-citationQiao, J., Zeng, R., Chen, Q., Zheng, D., Hao, P.-L., Liu, X., Zhao, F., & Zhang, X. (2023) · Nano Letters · doi:10.1021/acs.nanolett.3c00657 · Cited by 24
Chen, L., Liu, Y., Tang, Z., Shi, X., Song, Z., Cao, F., Wei, P., Li, M., Li, X., Jiang, D., et al. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.111131 · Cited by 24
Ji, M., Fang, C., Jia, W. P., Du, H., & Xu, Y. (2021) · Food & Function · doi:10.1039/d0fo03028g · Cited by 24
Personal diet–microbiota interactions and weight loss
Roager, H. M., & Christensen, L. H. (2022) · Proceedings of The Nutrition Society · doi:10.1017/s0029665122000805 · Cited by 23
An overview of traditional Chinese medicine affecting gut microbiota in obesity
Li, D., Tang, W., Wang, Y., Gao, Q., Zhang, H., Zhang, Y., Wang, Y., Yang, Y., Zhou, Y., Zhang, Y., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1149751 · Cited by 23
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Luo, M., Zhu, J., Jia, J., Zhang, H., & Zhao, J. (2024) · Applied and Environmental Microbiology · doi:10.1128/aem.00092-24 · Cited by 24
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The role of gut microbiota in insulin resistance: recent progress
Ji, H., Su, S., Chen, M., Liu, S., Liu, S., & Guo, J. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1633029 · Cited by 22
Sun, X. L., Chi, X., Zhao, Y., Liu, S., & Xing, H. (2022) · Journal of Diabetes Research · doi:10.1155/2022/1826181 · Cited by 22
Qiu, H., Kan, C., Han, F., Luo, Y., Qu, N., Zhang, K., Ma, Y., Hou, N., Wu, D., Sun, X., et al. (2024) · Lipids in Health and Disease · doi:10.1186/s12944-024-02198-7 · Cited by 22
MicroRNAs and extracellular vesicles in the gut: new host modulators of the microbiome?
Du, X., Ley, R. E., & Buck, A. H. (2021) · microLife · doi:10.1093/femsml/uqab010 · Cited by 20
Maltecca, C., Dunn, R. R., He, Y., McNulty, N. P., Schillebeeckx, C., Schwab, C. R., Shull, C. M., Fix, J., & Tiezzi, F. (2021) · Animal Microbiome · doi:10.1186/s42523-021-00118-z · Cited by 20
Song, H., Yi, S., Kim, W.-H., Guk, J.-H., Ha, M., Kwak, I., Han, J., Yeon, S., & Cho, S. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.01163-22 · Cited by 20
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Zheng, C., Chen, X., Tian, X. Y., Chun‐Hang, A., & Wong, S. H. (2022) · Obesity · doi:10.1002/oby.23345 · Cited by 20
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Wang, K., Liang, X., Pang, Y., & Jiang, C. (2019) · Small Methods · doi:10.1002/smtd.201900604 · Cited by 19
Bi, T., Zhang, L., Zhan, L., Feng, R., Zhao, T., Ren, W., Hang, T., Zhou, W., & Lu, X. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.913002 · Cited by 19
Wu, T., Yu, Q., Luo, Y., Dai, Z., Zhang, Y., Wang, C., Shen, Q., & Xue, Y. (2023) · Nutrients · doi:10.3390/nu15194186 · Cited by 19
Xia, C., Zhang, R., Jia, X., Dong, L., Ma, Q., Zhao, D. H., Lee, Y. K., Sun, Z., Huang, F., & Zhang, M. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.138734 · Cited by 19
Wu, P., Chiu, Y., Zou, H.-B., Hsu, C., Lee, S., Lin, Y., Tsai, Y., Kuo, M., & Hwang, S. (2019) · Nutrients · doi:10.3390/nu11123033 · Cited by 19
Shan, Y., Sun, C., Li, J., Shao, X., Wu, J., Zhang, M., Yao, H. L., & Wu, X. (2022) · Foods · doi:10.3390/foods11142034 · Cited by 19
Yang, Y., Cui, G., Qian, J., Xu, Y., Li, B., Shi, Y., Le, G., & Xie, Y. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.104255 · Cited by 18
Barraza-Ortega, E., Gómez‐Gil, B., García-Gasca, T., Lizárraga, D., Díaz, N., & García-Gasca, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26178574 · Cited by 18
Peng, Y., Xu, J., Zeng, C.-F., Zhao, X., Li, L., & Qi, L. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-1958 · Cited by 18
Liu, N., Song, Z., Jin, W., Yang, Y., Sun, S., Zhang, Y., Zhang, S., Liu, S., Ren, F., & Wang, P. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105234 · Cited by 18
Nakamura, S., Nakamura, K., Yokoi, Y., Shimizu, Y., Ohira, S., Hagiwara, M., Song, Z., Gan, L. H., Aizawa, T., Hashimoto, D., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-30997-y · Cited by 18
Lieberman, D. E., Worthington, S., Schell, L. D., Parkent, C. M., Devinsky, O., & Carmody, R. N. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.06.013 · Cited by 18
Akbuğa-Schön, T., Suzuki, T. A., Jakob, D., Vu, D. L., Waters, J. L., & Ley, R. E. (2023) · mBio · doi:10.1128/mbio.02836-23 · Cited by 18
Zhang, Y., Lou, J.-W., An, K., Zhang, Q., Zhou, S.-K., Bao, B., Cao, Y., Yao, W., Tang, Y., & Zhang, L. (2019) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2019.112423 · Cited by 18
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Dietz, M. W., Matson, K. D., Versteegh, M. A., van der Velde, M., Parmentier, H. K., Arts, J. A. J., Salles, J. F., & Tieleman, B. I. (2022) · Animal Microbiome · doi:10.1186/s42523-022-00216-6 · Cited by 17
Zou, Y., Zhang, Y., Wu, D., Lu, Z., Xiao, J., Huang, H., Fu, Q., & Guo, Z. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1326247 · Cited by 18
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Habibi, A., Letafatkar, N., Sattari, N., Nobakht, S., Rafat, Z., Moghadam, S. S., Mirdamadi, A., Javid, M., Jamilian, P., Hassanipour, S., et al. (2024) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2024.11.011 · Cited by 17
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Fernández-Jalao, I., Balderas, C., Calvo, M. V., Fontecha, J., Sánchez‐Moreno, C., & de Ancos, B. (2021) · Metabolites · doi:10.3390/metabo11050262 · Cited by 17
Ma, S., Shu, X., & Wang, W. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.151497 · Cited by 17
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Misra, B. B. (2020) · Biological Research For Nursing · doi:10.1177/1099800420903083 · Cited by 17
Ochoa‐Sánchez, M., Gómez, E. P. A., Ramírez-Fernández, L., Eguiarte, L. E., & Souza, V. (2023) · PeerJ · doi:10.7717/peerj.15978 · Cited by 16
Phenolic compounds in dietary target the regulation of gut microbiota: Role in health and disease
Zhang, Q., Xu, Y., Bukvički, D., Peng, Y., Li, F., Zhang, Q., Yan, J., Lin, S., Liu, S., & Qin, W. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105107 · Cited by 16
Yu, L., Lin, F., Yu, Y., Deng, X., Shi, X., Lu, X., Lu, Y., & Wang, D. Y. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.137878 · Cited by 16
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Tian, B., Wang, H., Zhang, Y., Lv, J., Li, D., Zhou, C., Xu, J., Ni, Y., Wu, B., Zhang, M., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.05.013 · Cited by 16
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Юрьевич, П. М., Михайловна, М. Ю., Efimochkina, N. R., Борисовна, К. И., & Анатольевна, Ш. С. (2020) · PubMed · doi:10.24411/0042-8833-2020-10040 · Cited by 16
Perrone, L., & Valente, M. (2021) · Biomolecules · doi:10.3390/biom11111652 · Cited by 16
Peng, Y., Zhao, X.-H., Zeng, C.-F., Xu, J., Qi, L., & Li, L. (2022) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo-21-906 · Cited by 16
Li, Z., Li, Y., Pan, B., Wang, X., Wu, Y. F., Guo, K., Yang, M., Ma, M., Qiao, C., & Yang, K. (2022) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-022-10037-3 · Cited by 16
Xiao, G., Qian, P., Benqiong, G., Zheng, Y., Fu, Z., Yang, D.-C., Zhu, C., Cao, Y., Niu, J., Ling, J., et al. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.1064737 · Cited by 16
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Lin, B., Bai, G., Zhang, Y., Wang, Y., & Chen, S. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.119417 · Cited by 15
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Galaris, A., Fanidis, D., Stylianaki, E.-A., Harokopos, V., Kalantzi, A.-S., Moulos, P., Dimas, A. S., Hatzis, P., & Aidinis, V. (2022) · Biomedicines · doi:10.3390/biomedicines10020494 · Cited by 15
Hernandez, A. R., Kemp, K. M., Burke, S. N., Buford, T. W., & Carter, C. S. (2022) · Nutrients · doi:10.3390/nu14091758 · Cited by 15
Li, D., Li, Y., Dai, W., Wang, H. H., Qiu, C., Feng, S., Zhou, Q., Wang, W., Feng, X., Yao, K., et al. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02635 · Cited by 15
Gaweł, E., Hall, B., Siatkowski, S., Grabowska, A., & Zwierzchowska, A. (2024) · Nutrients · doi:10.3390/nu16030355 · Cited by 14
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Jin, Q., Wang, S., Yao, Y., Jiang, Q., & Li, K. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-00531 · Cited by 14
Shen, Q., Qi, X., Liu, Y., Yang, Z., Hu, C., Zhao, L. Q., Zhan, H., Bian, H., & Ma, Y. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.139968 · Cited by 14
Su, S., Huang, K., Cai, H., Wei, D., Ding, H., Lin, L., Wang, Y., Gu, J., & Wang, Q. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156453 · Cited by 14
Meng, Y., Xiang, R., Yan, H., Zhou, Y., Hu, Y., Yang, J., Zhou, Y., & Cui, Q. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15472 · Cited by 14
Kang, Z.-Q., Hu, J.-L., Chen, M., Mao, Y., Xie, L.-F., Yang, N., Liu, T., Zhang, W., & Huang, W.-H. (2022) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x22500355 · Cited by 14
Wu, G. G., Tawfeeq, H. R., Lackey, A. I., Zhou, Y., Sifnakis, Z., Zacharisen, S. M., Xu, H.-L., Doran, J. M., Sampath, H., Zhao, L., et al. (2022) · Nutrients · doi:10.3390/nu14091762 · Cited by 14
Wei, J., Xiao, H., Wei, Y., Tsopmejio, I. S. N., Sun, C. L., Wu, H., Jin, Z., & Song, H. (2022) · mSystems · doi:10.1128/msystems.00835-22 · Cited by 14
Coutiño-Hernández, D., Sánchez‐Tapia, M., Leal-Vega, F. J., Bobadilla-del-Valle, M., Ledezma, H., Cervantes, R., Pedraza‐Chaverrí, J., Granados‐Portillo, O., Díaz, D., Antunes‐Ricardo, M., et al. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110856 · Cited by 14
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Lee, Y., Cho, J., & Cho, K. Y. (2023) · Nutrients · doi:10.3390/nu15092184 · Cited by 13
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Yu, K., Choi, I., Kim, M., Pyung, Y. J., Lee, J.-S., Choi, Y., Won, S., Kim, Y., Park, B.-C., Han, S. H., et al. (2025) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-025-01186-w · Cited by 13
Aljutaily, T., Aladhadh, M. A., Alsaleem, K. A., Alharbi, H. F., Barakat, H., Aljumayi, H., Moustafa, M. M. A., & Rehan, M. (2025) · Scientific Reports · doi:10.1038/s41598-025-96893-9 · Cited by 13
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Self-citation
Metadata
- Authors
- Cani, P. D., Van Hul, M., Lefort, C., Depommier, C., Rastelli, M., & Everard, A.
- Affiliations
- Walloon Excellence in Lifesciences and Biotechnology (BE)
- Corresponding author
- Cani, Patrice D.
- Venue
- Nature Metabolism
- Published
- 2019-01-07
- Volume
- 1
- Issue
- 1
- Pages
- 34-46
- ISSN
- 2522-5812 (ISSN-L)
- OpenAlex
- W2907048060
- Cited by
- 569
- References
- 210
- Citations by year
- 2026: 55 · 2025: 68 · 2024: 88 · 2023: 79 · 2022: 100 · 2021: 94 · 2020: 54 · 2019: 31
- FWCI
- 4.39
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Nature Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion, other-oa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
- Keywords
- gut microbiota, energy homeostasis, host metabolism, short-chain fatty acids, gastrointestinal hormones, food intake regulation, thermogenesis, brown adipose tissue, bile acids, branched-chain amino acids, endocannabinoids, antibiotics, physical activity, microbiota-based therapy, metabolic disorders
- MeSH terms
- Gastrointestinal Microbiome, Animals, Energy Metabolism, Fatty Acids, Volatile, Homeostasis, Humans, Organ Specificity, Biomarkers, Biodiversity, Host-Pathogen Interactions, Microbiota
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