The DOI matches its Crossref record; 232 of the 232 references it cites were found in a registry or an index.
Nanodelivery of nucleic acids
Open accessAbstract
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented opportunity to overcome these drawbacks; owing to their tunability with diverse physico-chemical properties, they can readily be functionalized with any type of biomolecules/moieties for selective targeting. Nucleic acid therapeutics such as antisense DNA, mRNA, small interfering RNA (siRNA) or microRNA (miRNA) have been widely explored to modulate DNA or RNA expression Strikingly, gene therapies combined with nanoscale delivery systems have broadened the therapeutic and biomedical applications of these molecules, such as bioanalysis, gene silencing, protein replacement and vaccines. Here, we overview how to design smart nucleic acid delivery methods, which provide functionality and efficacy in the layout of molecular diagnostics and therapeutic systems. It is crucial to outline some of the general design considerations of nucleic acid delivery nanoparticles, their extraordinary properties and the structure-function relationships of these nanomaterials with biological systems and diseased cells and tissues.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Modulation of surface characteris tics may help to improve transduction and reduce the dose required, thereby reducing the risk of GTAU (Mendes et al., 2022; Carvalho et al., 2023).”
From Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy (2025) · cites this paper as Mendes et al., 2022
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Vos, T., Lim, S. S., Abbafati, C., Abbas, K. M., Abbasi, M., Abbasifard, M., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., Abdelalim, A., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30925-9 · Cited by 19,358
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012) · Science · doi:10.1126/science.1225829 · Cited by 17,116
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Polack, F. P., Thomas, S. J., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Perez, J. L., Pérez Marc, G., Moreira, E. D., Zerbini, C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2034577 · Cited by 14,592
Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019
Roth, G. A., Mensah, G. A., Johnson, C. O., Addolorato, G., Ammirati, E., Baddour, L. M., Barengo, N. C., Beaton, A. Z., Benjamin, E. J., Benziger, C. P., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.11.010 · Cited by 11,449
Engineering precision nanoparticles for drug delivery
Mitchell, M. J., Billingsley, M. M., Haley, R. M., Wechsler, M. E., Peppas, N. A., & Langer, R. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-020-0090-8 · Cited by 7,933
Forouzanfar, M. H., Afshin, A., Alexander, L. T., Anderson, H. R., Bhutta, Z. A., Biryukov, S., Brauer, M., Burnett, R., Cercy, K., Charlson, F. J., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31679-8 · Cited by 7,698
Stimuli-responsive nanocarriers for drug delivery
Mura, S., Nicolas, J., & Couvreur, P. (2013) · Nature Materials · doi:10.1038/nmat3776 · Cited by 6,289
mRNA vaccines — a new era in vaccinology
Pardi, N., Hogan, M. J., Porter, F. W., & Weissman, D. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.243 · Cited by 4,667
Renal clearance of quantum dots
Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476
Research works printed but not linked: 1
- Malaviya, M. & Shiroya, M. Systemic gene delivery using lipid envelope systems and its potential in overcoming challenges. Int. J. Pharm. Drug Anal. 9, 46–55 (2021).
Cited by
Sorted by citations
Items 401–500 of 764
Huang, P., Pistono, P. E., Martin, H. S., Fetzer, J. L., & Francis, M. B. (2025) · ACS Chemical Biology · doi:10.1021/acschembio.5c00125 · Cited by 5
Liu, C., Tang, Y., Yin, X., Yan, Y., Meng, C., Zhang, Y., Wang, L., Han, R., Qiao, X., Schetelig, M. F., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.146520 · Cited by 5
Ferreira, H. A. S., Guimarães, L. C., Costa, P. A. C., de Campos, C. L. V., Scalzo, S., Queiroz‐Junior, C. M., Figueiredo, M. M., Teixeira, M. M., Costa, V. V., & Guimarães, P. P. G. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.126073 · Cited by 5
Li, J., Ma, R., Jiang, Q., Zhou, B., Yan, S., Shen, J., & Yin, M. (2025) · ACS Applied Nano Materials · doi:10.1021/acsanm.5c03209 · Cited by 5
Innovative Lipid-Based Nanobiotechnology: Diagnostics and Medicine
Seo, S. E., Kim, K. H., Singh, S., Chen, J.-S., Iijima, S., Cheng, C., Ryu, Y., Song, H. S., Li, W., & Kwon, O. S. (2026) · ACS Nano · doi:10.1021/acsnano.5c16718 · Cited by 5
Engineered strategies for enhancing mRNA vaccine stability in delivery and storage
Cerav, E. N., Yao, Z., & Sun, B. (2026) · Nanoscale · doi:10.1039/d5nr05189d · Cited by 5
Shaw, S., Mandal, S., Mukherjee, N., Das, S., & Jana, N. R. (2026) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5c25970 · Cited by 5
Yan, X., Liu, J., Liu, J., Wei, S., Li, R., Mu, W., Zhang, N., & Liu, Y. (2026) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2026.101119 · Cited by 5
Nano-enabled RNA interference: emerging trends in the sustainable management of lepidopteran pests
Ullah, F., Govindharaj, G., Yan, S., Haider, K., Sarangi, S., Gul, H., Li, X., Guedes, R. N. C., Desneux, N., & Lu, Y. (2026) · Journal of Pest Science · doi:10.1007/s10340-026-02027-z · Cited by 5
Nanocarrier-Mediated RNAi: Breaking the dsRNA Delivery Bottleneck in Crop Protection
Wang, Q., Li, C., Yang, R. (., Wang, Y., & Zhang, N. (2026) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.6c04952 · Cited by 5
Drug delivery breakthrough technologies – A perspective on clinical and societal impact
Bittner, B., Sánchez-Félix, M., Lee, D., Koynov, A. A., Horvath, J. D., Schumacher, F. F., & Matoori, S. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.06.034 · Cited by 5
Zhang, J., Liu, S., Wang, Y., Li, X., Zeng, H., Li, B., & Wang, J. (2024) · Langmuir · doi:10.1021/acs.langmuir.3c03874 · Cited by 5
Xie, X., Nan, H., Peng, J., Zeng, K., Wang, H., Huang, Y., & Nie, Z. (2024) · Angewandte Chemie · doi:10.1002/ange.202410380 · Cited by 5
Biomaterial‐Mediated Metabolic Regulation of Ferroptosis for Cancer Immunotherapy
Liu, Y., Tao, D., Li, M., & Luo, Z. Y. (2024) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.2010 · Cited by 5
Shaulli, X., Moreno‐Echeverri, A. M., Andoni, M., Waeber, E. L., Ramakrishna, S. N., Fritsch, C., Vanhecke, D., Rothen‐Rutishauser, B., & Scheffold, F. (2024) · Small · doi:10.1002/smll.202405929 · Cited by 5
Xia, Y., Ju, G., Zhou, Y., Li, X., Luo, Y., Peng, C., & Liu, X. (2024) · Analytica Chimica Acta · doi:10.1016/j.aca.2024.343557 · Cited by 5
Inside the cell: Approaches to evaluating mRNA internalization and trafficking
Runzer, C. D. T., Plank, C., van Griensven, M., & Balmayor, E. R. (2025) · Methods · doi:10.1016/j.ymeth.2025.06.006 · Cited by 5
Tafere, C., Siraj, E. A., Yayehrad, A. T., & Workye, M. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.125848 · Cited by 5
Transformable Nanotheranostics Capable of Sensoring Nucleic Acid Drugs’ Spatiotemporal Behaviors
Shen, J., Wang, J., Hao, Q., Ji, W., Peng, H., Wu, Y., Zhao, R., Qiu, X., Wang, W., Yang, H. J., et al. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202209749 · Cited by 5
Takatsu, M., Morihiro, K., Watanabe, H., Yuki, M., Hattori, T., Noi, K., Aikawa, K., Noguchi, K., Yohda, M., Okazoe, T., et al. (2023) · ACS Chemical Biology · doi:10.1021/acschembio.3c00612 · Cited by 5
Gene therapy shines light on congenital stationary night blindness for future cures
Zhang, Y., Lin, S., Yu, L., Lin, X. Y., Qu, S., Ye, Q., Yu, M., Chen, W., & Wu, W. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06392-8 · Cited by 4
The Journey and Modes of Action of Therapeutic Nanomaterials in Cells
Sahli, C., & Kenry, K. (2025) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.4c00584 · Cited by 4
Beltrame, B. M., Weimer, P., Medeiros-Neves, B., Gentil, G. F. S., Stefani, M. A., Velho, M. C., Fachel, F. N. S., Schuh, R. S., Braganhol, E., & Teixeira, H. F. (2025) · Nanomedicine · doi:10.1080/17435889.2025.2574249 · Cited by 4
Self-assembly of short peptides and DNA-based materials in precision biomedical applications
Das, A., Vaghela, D., Gupta, S. K., Bhatia, D. D., & Biswas, A. (2025) · Supramolecular Materials · doi:10.1016/j.supmat.2025.100123 · Cited by 4
Yang, W., Luo, X., Chen, M., Li, Y., Li, Y., Chen, X., Shao, Y., & Xu, F. (2025) · Science China Technological Sciences · doi:10.1007/s11431-025-3101-1 · Cited by 4
Advancing Gene Therapy for Pancreatitis: From Genetic Insights to Clinical Translation
Zheng, Y.-Z., Wang, Y., Qi, H.-M., Gao, J., Li, Z., Liao, Z., & Zou, W. (2026) · Research · doi:10.34133/research.1154 · Cited by 4
A worm-like nucleic acid nanostructure for gene delivery and endosomal escape via ClC3 ion exchanger
Xiao, Y., Chan, C. K. W., Lee, L. K. C., Shyngys, M., Chiu, Y. T. E., Xue, E. Y., Lui, K. O.-L., Chan, H. Y. E., Leung, S. S. Y., Yao, X., et al. (2026) · Science Advances · doi:10.1126/sciadv.adw0891 · Cited by 4
Self-citationDecoding nucleic acid contributions to phase separation and ordering in biomolecular condensates
Asnicar, D., Codispoti, S., Morasso, C., Ferrarini, A., & Zanchetta, G. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag253 · Cited by 4
Acid-Responsive Drug Delivery Systems: Advances and Perspectives
Zhong, H., Zong, Y., Du, H., Wang, J., Qu, S., Gong, N., Yu, B., Cheng, Q., & Guo, S. (2026) · Polymer science & technology. · doi:10.1021/polymscitech.6c00051 · Cited by 4
Diameter-Optimum Spreading for the Impinging of Water Nanodroplets on Solid Surfaces
Tan, J., Guo, Y., & Guo, W. (2023) · Langmuir · doi:10.1021/acs.langmuir.3c00983 · Cited by 4
Deng, J. Z., Song, W., Lu, T., Alkurdi, E., Smith, W. J., Mukherjee, M., & Zhuang, P. (2025) · Journal of Chromatography A · doi:10.1016/j.chroma.2025.466174 · Cited by 4
Recent advances and clinical prospects of non-viral brain-targeted gene delivery systems
Wang, S., Xu, L.-L., Ma, F., Xu, M., Chen, G., Wang, D., Wu, X., Wang, P., Yu, J., & Shi, L. (2025) · Applied Physics Reviews · doi:10.1063/5.0255745 · Cited by 4
Nonviral DNA delivery’s recent successes and final hurdles
Tiwari, S., Patel, M. N., & Brenner, J. S. (2025) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/j.jpet.2025.103734 · Cited by 4
Ortega‐Caballero, F., Santana‐Armas, M. L., de Ilarduya, C. T., Giorgio, C. D., Tripier, R., Bris, N. L., Ollier, C., Mellet, C. O., Fernández, J. M. G., Blanco, J. L. J., et al. (2024) · Journal of Materials Chemistry B · doi:10.1039/d3tb02889e · Cited by 4
Covalent Polymer‐RNA Conjugates for Potent Activation of the RIG‐I Pathway
Palmer, C. R., Pastora, L. E., Kimmel, B. R., Pagendarm, H. M., Kwiatkowski, A. J., Stone, P. T., Arora, K., Francini, N., Fedorova, O., Pyle, A. M., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202303815 · Cited by 4
Therapeutic Efficacy of Nanocarrier‐Mediated Inhalable Gene Transfection for Lung Cancer
Sarkar, P., Sardar, M., Sen, O., Das, S., & Manna, S. (2024) · ChemistrySelect · doi:10.1002/slct.202402903 · Cited by 4
Self-assembled nanoparticles of PEG and poly(2-oxazoline) based lactide block copolymers
Godzina, M., Terracciano, R., Varanaraja, Z., MacKinnon, D. J., & Becer, C. R. (2024) · European Polymer Journal · doi:10.1016/j.eurpolymj.2024.113517 · Cited by 4
Ψαρρού, Μ., Vamvakaki, M., Karatasos, K., & Rissanou, A. N. (2024) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2024.114386 · Cited by 4
Henaish, A. M., Mira, N. M., Zoghroban, H. S., Moussa, E. A., Helal, I. B., El‐Mehasseb, I. M., & El‐Shafai, N. M. (2024) · Journal of Dispersion Science and Technology · doi:10.1080/01932691.2024.2434704 · Cited by 4
Liu, S., Ji, Z., Ge, S., Cai, C., Zhang, H., Wang, Y., Zhou, Y., Zhou, J., Cheng, H., & Ding, Y. (2025) · Nano Letters · doi:10.1021/acs.nanolett.5c00878 · Cited by 4
Migone, C., Fabiano, A., Zambito, Y., Piccarducci, R., Marchetti, L., Giacomelli, C., Martini, C., & Piras, A. M. (2025) · Applied Biosciences · doi:10.3390/applbiosci4020029 · Cited by 4
Timin, A. S., Rusakova, V. A., Ilina, K. E., Rogova, A. S., Tishchenko, Y. A., Akhmetova, D. R., Gorbunova, I. A., Shipilovskikh, D. A., Lipin, D. V., & Shipilovskikh, S. A. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114020 · Cited by 4
Rachana, R., Devtalla, H., Rana, K., Panda, S. P., Agrawal, A., Kadyan, S., Jindal, D., Pancham, P., Yadav, D., Jha, N. K., et al. (2023) · Chemical Biology & Drug Design · doi:10.1111/cbdd.14374 · Cited by 4
Enhancing Gene Therapy through Ultradeformable Vesicles for Efficient siRNA Delivery
Aundhia, C. J., Shah, N. V., Talele, C., Zanwar, A. S., Kumari, M., & Patil, S. (2024) · Pharmaceutical Nanotechnology · doi:10.2174/0122117385271654231215064542 · Cited by 4
Liu, W., Li, H., & Bai, G. (2024) · Nucleosides Nucleotides & Nucleic Acids · doi:10.1080/15257770.2024.2334353 · Cited by 4
Barnaud, L., Fukuhara, S., Pava, M., Carrasco, M., Aviñó, A. M., Eritja, R., Rodríguez‐Abreu, C., & Grijalvo, S. (2024) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2024.105959 · Cited by 4
Engineering immunotherapy from within
Peche, V. S., & Gottschalk, S. M. (2025) · Science · doi:10.1126/science.ady7928 · Cited by 4
Betsy Reshma, G., Miglani, C., Pal, A., & Ganguli, M. (2024) · Nanoscale · doi:10.1039/d3nr05300h · Cited by 3
Cationic cycloamylose based nucleic acid nanocarriers
Prasher, P., Sharma, M., Agarwal, V., Singh, S. K., Gupta, G., Dureja, H., & Dua, K. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.111000 · Cited by 3
Subramanian, R., Chinnadurai, G., Suresh, R., Santhamoorthy, M., Periyasami, G., Karthikeyan, P., Mohan, A., & Phan, T. T. V. (2024) · Zeitschrift für Physikalische Chemie · doi:10.1515/zpch-2023-0505 · Cited by 3
Development of Focused Ultrasound-Assisted Nanoplexes for RNA Delivery
Ranjan, S. K., Bosch, S., Lukkari, H., Schirmer, J., Aaltonen, N., Nieminen, H. J., Lehto, V., Urtti, A. O., Lajunen, T., & Rilla, K. J. (2024) · Nanomaterials · doi:10.3390/nano14131089 · Cited by 3
Ijaz, M., Ahmed, T., Ijaz, R., Noman, M., Guo, J., Ali, H. M., & Li, B. (2024) · Springer eBooks · doi:10.1007/978-981-97-1699-9_23 · Cited by 3
Hameed, H., Sarwar, H. S., Younas, K., Zaman, M., Jamshaid, M., Irfan, A., Khalid, M., & Sohail, M. F. (2024) · Functional & Integrative Genomics · doi:10.1007/s10142-024-01459-z · Cited by 3
Exploring Nanomedicine Ventures and Latest Developments in Clinical Trials
Patil, U. D. (2024) · Nanotechnology in the life sciences · doi:10.1007/978-3-031-72467-1_16 · Cited by 3
One-pot modular nanogel platform utilizing phenolic gelatin-polyethyleneimine for small RNA delivery
Park, K., Zheng, J., Yoo, J.-E., Kim, J., Kim, I.-Y., & You, S. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.159532 · Cited by 3
Inhibition of PCSK9 with polypurine reverse hoogsteen hairpins: A novel gene therapy approach
López-Aguilar, E., Pacheco-Velázquez, S. C., Busquets, M.-A., Hay, J., Mueller, P. A., Fazio, S., Ciudad, C. J., Noé, V., & Pamir, N. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.116976 · Cited by 3
Ternary nanoparticle rigidity regulates mRNA vaccines transportation
Zhao, C., Li, L., Wang, C., Liu, X., & Deng, H. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123628 · Cited by 3
Nanotechnology for RNA and DNA Delivery in Cancer Therapeutics
Safo, K. K., Ogoe, M., George, N., Gupta, A., Janiyani, K., Singh, H., Babu, K. G., & Pandya, S. R. (2025) · Series in bioengineering · doi:10.1007/978-981-95-0457-2_7 · Cited by 3
A naturally derived lipopeptide lipid nanoparticle platform enabling multiple nucleic acids delivery
Han, X., Feng, B., Gao, D., Shi, S., Yang, Y., Zhang, Y., Wang, F., Yao, Q., Song, H., Liu, Y., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.09.007 · Cited by 3
Yang, Q., Sang, Y., Geng, N., Liu, Y., Zhang, D., Zou, Y., & Zheng, M. (2025) · Nano Today · doi:10.1016/j.nantod.2025.102903 · Cited by 3
Recent advances in gene delivery for melanocyte-associated disorders
Chhibber, T., Deacon, D. C., Ghandehari, H., & Judson‐Torres, R. L. (2025) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2025.115703 · Cited by 3
Loop-Structured PEG-Lipoconjugate Enhances siRNA Delivery Mediated by Liner-PEG Containing Liposomes
Gladkikh, D. V., Shmendel, E. V., Makarova, D. M., Maslov, M. A., Аркадьевна, З. М., & Chernolovskaya, E. L. (2025) · Molecules · doi:10.3390/molecules30204127 · Cited by 3
Zhang, S., Li, Y., Yang, B., Teymur, A. A., Atrooz, F., Majd, S., Mohan, C., Salim, S., & Wu, T. (2025) · Scientific Reports · doi:10.1038/s41598-025-21877-8 · Cited by 3
Mantashlou, M. J., Sarvmeili, J., Mohajeri, N., Hampaei, F., Moghaddam, S. V., & Alizadeh, E. (2025) · Cancer Nanotechnology · doi:10.1186/s12645-025-00356-9 · Cited by 3
Advances in the Development of Lipid Nanoparticles for mRNA Delivery
Wang, X., Xu, L., Lan, Z., Hui, Y., Liu, Y., Yang, G., & Zhao, C. (2026) · Small Structures · doi:10.1002/sstr.202500568 · Cited by 3
Vertex‐Integrated Tetrahedral DNA Nanoframe Enhances miR‐143‐3p Delivery for Osteoarthritis Therapy
Chen, X., Miao, T., Yin, W., Xu, X., He, Y., Gao, Y., & Lin, Y. (2026) · Small · doi:10.1002/smll.202511570 · Cited by 3
Spermine Lipid Assembled Nanoparticles for siRNA Delivery and Androgenetic Alopecia Therapy
Feng, D., Hu, Y. M., Zhang, Z., Fan, X., Man, Y., Wang, Z., Guo, D. R., Song, Y., Zhou, J., Zhang, J., et al. (2026) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5c26100 · Cited by 3
Wang, Z., Li, Q., Huang, Q., Zheng, N., Zhai, B., Guo, D., Luan, F., Zou, J., & Shi, Y. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.177298 · Cited by 3
Bukke, S. P. N., Thalluri, C., Medhi, J., Vasam, M., Samanthula, K. S., Chettupalli, A. K., Gupta, N., Kumar, P. S., & Naik, B. P. (2026) · Journal of Biomaterials Science Polymer Edition · doi:10.1080/09205063.2026.2684336 · Cited by 3
Belkare, C. K., & Daware, O. V. (2026) · DARU Journal of Pharmaceutical Sciences · doi:10.1007/s40199-026-00617-x · Cited by 3
In vivo delivery strategies for therapeutic CRISPR genome editing
Martin, L., Bohinc, J., Recchia, A., Gritti, S., Santilli, G., Zeyland, J., Vidaković, M., Grdović, N., Benabdellah, K., Ortiz-Bueno, M., et al. (2026) · International Journal of Biological Sciences · doi:10.7150/ijbs.133162 · Cited by 3
Oliveira, I. S., Silva, S. G., Gomes, A. C., Oliveira, M. E. C. D. R., Vale, M. L. C., & Marques, E. F. (2024) · Journal of Functional Biomaterials · doi:10.3390/jfb15080224 · Cited by 3
Lipid-based nanoparticles for nucleic acids delivery
Sarnelli, S., Cardamone, M., Reverchon, E., & Baldino, L. (2025) · Physical Sciences Reviews · doi:10.1515/psr-2025-0001 · Cited by 3
Ovechkina, V. S., Andrianova, S. K., Shimanskaia, I. O., Suvorova, P. S., Ryabinina, A. Y., Blagonravov, M. L., Belousov, V. V., & Mozhaev, A. A. (2025) · ACS Chemical Biology · doi:10.1021/acschembio.4c00842 · Cited by 3
The Contribution of Nanomedicine in Ocular Oncology
Spyratou, E., Margarita, T., Droulias, A., Zachou, M.-E., & EFSTATHOPOULOS, E. P. (2025) · Cancers · doi:10.3390/cancers17071186 · Cited by 3
Multiprotein Silencing Using WRAP-Based Nanoparticles: A Proof of Concept
Konate, K., Pezzati, I., Redjatti, K., Agnel, E., Vivès, É., Faure, S., Barbara, P. D. S., Boisguérin, P., & Deshayes, S. (2025) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5c00069 · Cited by 3
楊, 栄., Yao, T., Xu, J., Liu, X., Yang, Y., Ding, J., Cao, C., Su, R., Li, S., Lu, W., et al. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c00749 · Cited by 3
Is it Time for Multi‐Drug Therapy with Combination of Therapeutic Nucleic Acids?
Lesnikowski, Z. J. (2024) · ChemMedChem · doi:10.1002/cmdc.202400493 · Cited by 3
Nanodelivery systems for gene editing drugs
Zhang, Y., & Ping, Y. (2025) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/tb-2025-0178 · Cited by 3
Silva, R., Monteiro, J., Ramalho, M. J., Andrade, S., Loureiro, J. A., & Pereira, M. C. (2026) · Pharmaceuticals · doi:10.3390/ph19050685 · Cited by 2
“…expression of specific genes by inserting a functional gene copy to be expressed (e.g., mRNA) and even amplify, surpress, or correct gene expression, consequently resulting in gain or loss of function (e.g., clustered regularly interspaced short palindromic repeats (CRISPR)/Cas systems) [98,99].”
Nanotherapeutics for Colorectal Cancers Using Nanobiomaterials
Jalise, S. Z., Kheirkhah, A. H., Poondla, N., Sardarabadi, H., & Sheykhhasan, M. (2026) · Nanotechnology in the life sciences · doi:10.1007/978-3-032-08576-4_1 · Cited by 2
Shmendel, E. V., Markov, O. V., Аркадьевна, З. М., & Maslov, M. A. (2024) · Biological Products Prevention Diagnosis Treatment · doi:10.30895/2221-996x-2024-24-2-188-199 · Cited by 2
Mechanistic study of plasmid DNA delivery by Magainin 2-derived stapled peptides
Hirano, M., Takechi‐Haraya, Y., Abe, Y., Misawa, T., Shibata, N., Sato, Y., & Demizu, Y. (2025) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2025.118176 · Cited by 2
Inkjet printing of lipoplexes: A feasibility study
Krabbes, M., Kieckhöfer, M., Schmidt, C., Haas, V., Büttner, M., Schoeder, C. T., Wagner, U. G., Kaysser, L., Wölk, C., & Schulz‐Siegmund, M. (2025) · Applied Materials Today · doi:10.1016/j.apmt.2025.102699 · Cited by 2
Gel encapsulation: A novel approach to enhance material performances!
Beri, D., Budiman, S., Oktasendra, F., Sudiar, N. Y., Yohandri, Y., Ganefri, G., & Amran, A. (2025) · Results in Chemistry · doi:10.1016/j.rechem.2025.102574 · Cited by 2
Hoshino, R., Sugawara, K., Terashita, K., Shimamura, H., Toshima, J., Arimura, G., & Akiyama, Y. (2025) · Biomaterials Advances · doi:10.1016/j.bioadv.2025.214477 · Cited by 2
Keim, D. A., Dehne, M., Miller, P. J., Jérôme, V., Bahnemann, J., & Freitag, R. (2025) · Chem & Bio Engineering · doi:10.1021/cbe.5c00059 · Cited by 2
Low‐cost, handheld, multi‐pulse electroporators for simplified nucleic acid delivery in skin
Rohilla, P., Azizoğlu, E., Park, S., Lele, A., Prausnitz, M. R., & Bhamla, M. S. (2025) · Bioengineering & Translational Medicine · doi:10.1002/btm2.70070 · Cited by 2
Xu, M., Wang, H., Wang, C., Wang, C., Hu, S., & Weng, L. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.126221 · Cited by 2
Recent advances in nucleic acid nanotechnology-driven artificial transcriptional components
Jiao, K., Zhai, W., Peng, H., Guo, L., Li, J., Cai, G., & Wang, L. (2025) · Nanoscale · doi:10.1039/d5nr03210e · Cited by 2
When microfluidics meets pharmaceutical analysis
Ai, Y., Li, L., Xie, R., Wang, P., Guo, H., Ren, F., He, M., & Liang, Q. (2025) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2025.118518 · Cited by 2
Zhou, B., Yang, J., Zhang, B., Wang, W., Li, J., & Zhang, Y. (2025) · ChemBioChem · doi:10.1002/cbic.202500545 · Cited by 2
Tang, W., Tong, T., Deng, L. J., Zhang, Q., Tan, Y., Yu, Y., Lv, F., Zhang, C., Gong, Q., Dong, J., et al. (2025) · Science China Chemistry · doi:10.1007/s11426-025-3041-3 · Cited by 2
Darmadi, D., Aghazadeh-Habashi, K., Ayvazyan, S. R., Bozorgnia, A., & Khodabandehloo, E. (2025) · Discover Oncology · doi:10.1007/s12672-025-03843-y · Cited by 2
Davoudinia, S., Imani, R., Tafazzoli‐Shadpour, M., Fani, N., & Makki, H. (2025) · Nanoscale · doi:10.1039/d5nr03441h · Cited by 2
Giusti, A. M., Eusébio, D., Costa, M., Silveira, I., Biswas, S., Costa, D., & Sousa, Â. (2025) · Vaccines · doi:10.3390/vaccines14010018 · Cited by 2
Castro, C. G., Duarte, K. E., dos Reis, R. A., Moreira, V. A., Lombello, R. A., Castro, J. C., Seabra, A. B., & Centeno, D. C. (2025) · Plant Nano Biology · doi:10.1016/j.plana.2025.100243 · Cited by 2
Zhang, M., Pan, X., Li, J., & Wang, H. (2026) · Chinese Chemical Letters · doi:10.1016/j.cclet.2026.112358 · Cited by 2
Lu, H., Huang, Q., Xiong, Z., Wu, C., Ren, S., Wang, X., & Shi, J. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.172968 · Cited by 2
Self-citationWang, Y., Ni, D., Yao, D., & Deng, Z. (2026) · ChemPlusChem · doi:10.1002/cplu.202500680 · Cited by 2
Self-citation
Metadata
- Authors
- Mendes, B. B., Conniot, J., Avital, A., Yao, D., Jiang, X., Zhou, X., Sharf-Pauker, N., Xiao, Y., Adir, O., Liang, H., Shi, J., Schroeder, A., & Conde, J.
- Affiliations
- Ningbo University (CN)
- University of Science and Technology of China (CN)
- Brigham and Women's Hospital (US)
- Technion – Israel Institute of Technology (IL)
- Universidade Nova de Lisboa (PT)
- Corresponding author
- Liang, Haojun
- Shi, Jinjun
- Schroeder, Avi
- Conde, João
- ORCID
- Venue
- Nature Reviews Methods Primers
- Published
- 2022-04-14
- Volume
- 2
- Issue
- 1
- ISSN
- 2662-8449 (ISSN-L)
- PMC
- PMC9038125
- OpenAlex
- W4223968391
- Cited by
- 719
- References
- 228
- Citations by year
- 2026: 166 · 2025: 233 · 2024: 196 · 2023: 103 · 2022: 21
- FWCI
- 14.40
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Nature Reviews Methods Primers (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
- Funders
- U.S. Department of Veterans Affairs (I01 BX004426)
- American Lung Association
- Massachusetts General Hospital
- National Natural Science Foundation of China (52003264, 21991132, 52033010, 2020YFA0710700, 52021002)
- National Institutes of Health
- Fundação para a Ciência e a Tecnologia (PTDC/BTM-MAT/4738/2020)
- Fundamental Research Funds for the Central Universities
- National Heart, Lung, and Blood Institute (R01HL159012, R01HL156362, R01HL137229, R01HL158097, R01HL162367)
- National Cancer Institute (R01CA200900)
- H2020 European Research Council (848325)
- DOD Peer Reviewed Cancer Research Program
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Physical Sciences › Materials Science › Polymers and Plastics › Dendrimers and Hyperbranched Polymers
- Keywords
- nucleic acid delivery, nanodelivery, gene therapy, nanoparticles, siRNA, microRNA, antisense DNA, mRNA therapeutics, targeted delivery, structure-function relationship, molecular diagnosis, gene silencing, vaccines, protein replacement
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
