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Cited by 341

The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.

Machine learning and deep learning applications in microbiome research

Open access
Hernández Medina, Ricardo, Kutuzova, Svetlana, Nielsen, Knud Nor, Johansen, Joachim, Hansen, Lars Hestbjerg, Nielsen, Mads, Rasmussen, Simon·2022·ISME Communications

Abstract

The many microbial communities around us form interactive and dynamic ecosystems called microbiomes. Though concealed from the naked eye, microbiomes govern and influence macroscopic systems including human health, plant resilience, and biogeochemical cycling. Such feats have attracted interest from the scientific community, which has recently turned to machine learning and deep learning methods to interrogate the microbiome and elucidate the relationships between its composition and function. Here, we provide an overview of how the latest microbiome studies harness the inductive prowess of artificial intelligence methods. We start by highlighting that microbiome data – being compositional, sparse, and high-dimensional – necessitates special treatment. We then introduce traditional and novel methods and discuss their strengths and applications. Finally, we discuss the outlook of machine and deep learning pipelines, focusing on bottlenecks and considerations to address them.

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Metadata

Authors
Hernández Medina, R., Kutuzova, S., Nielsen, K. N., Johansen, J., Hansen, L. H., Nielsen, M., & Rasmussen, S.
Venue
ISME Communications
Published
2022-10-06
Volume
2
Issue
1
Pages
98-98
ISSN
2730-6151 (ISSN-L)
OpenAlex
W4302426080
Cited by
341
References
94
FWCI
15.68
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Machine learning and deep learning applications in microbiome research. https://app.cochat.ai/papers/10.1038/s43705-022-00182-9
The paper
Hernández Medina, R., Kutuzova, S., Nielsen, K. N., Johansen, J., Hansen, L. H., Nielsen, M., & Rasmussen, S. (2022). Machine learning and deep learning applications in microbiome research. ISME Communications. https://doi.org/10.1038/s43705-022-00182-9

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