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Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies
Open accessAbstract
Cohort studies of excess body weight and risk of liver cancer were identified for a meta-analysis by searching MEDLINE and EMBASE databases from 1966 to June 2007 and the reference lists of retrieved articles. Results from individual studies were combined using a random-effects model. We identified 11 cohort studies, of which seven on overweight (with a total of 5037 cases) and 10 on obesity (with 6042 cases) were suitable for meta-analysis. Compared with persons of normal weight, the summary relative risks of liver cancer were 1.17 (95% confidence interval (CI): 1.02-1.34) for those who were overweight and 1.89 (95% CI: 1.51-2.36) for those who were obese. This meta-analysis finds that excess body weight is associated with an increased risk of liver cancer.
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Metadata
- Authors
- Larsson, S. C., & Wolk, A.
- Venue
- British Journal of Cancer
- Published
- 2007-08-14
- Volume
- 97
- Issue
- 7
- Pages
- 1005-1008
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- OpenAlex
- W2165778365
- Cited by
- 495
- References
- 3
- FWCI
- 0.89
- Type
- journal article
- Language
- en
- Open access
- hybrid
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