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SGIP1 Deletion in Mice Attenuates Mechanical Hypersensitivity Elicited by Inflammation

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Fatty Pain Cures

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Bioactive Lipids in Nociception

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Functional Autoradiography as a Pharmacological Approach for Studying G Protein-Coupled Lipid Receptor Signalling

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Philosophy at Virginia Commonwealth University.

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Analysis of the structure and function of endocannabinoid-hydrolyzing enzymes using biophysical and nanomedical techniques

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Biochemical and biophysical characterization of human monoacylglycerol lipase in solution and in the presence of nanodisc membrane models

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Design, synthesis, methodology development, and evaluation of PET imaging agents targeting cancer and CNS disorders

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New target proteins for drug discovery in colon cancer

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Differential roles of the two major endocannabinoid hydrolyzing enzymes in cannabinoid receptor tolerance and somatic withdrawal

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The mechanism of monoacylglycerol lipase (MGL) inactivation

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Therapeutic implications of the endocannabinoid system in neurodegenerative diseases

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URB602

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Advances in Small Molecule Research Targeting Monoacylglycerol Lipase in Drug Discovery

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BindingDB Entry 50030705: Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors.

BindingDB (2010) · UC San Diego · doi:10.7270/q2tm7b59

BindingDB Entry 4628: Discovery of potent and reversible monoacylglycerol lipase inhibitors.

BindingDB (2011) · UC San Diego · doi:10.7270/q2hh6hj3

BindingDB Entry 50000616: Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

BindingDB (2019) · UC San Diego · doi:10.7270/q2jm2d3v

BindingDB Entry 4617: URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.

BindingDB (2011) · UC San Diego · doi:10.7270/q2xs5sw0

Inhibitors of monoacylglycerol lipase as novel analgesics

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Behavioral and Anti-inflammatory Effects of MAGL Inhibition in a Mouse Model of Inflammatory Arthritis

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Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor

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