Body composition analysis by dual energy X-ray absorptiometry in female diabetics differ between manufacturers
Abstract
Objective Comparison of body composition results by two dual energy X-ray absorptiometry (DXA) instruments, namely QDR-2000 from Hologic Inc and from Lunar in subpopulations of lean and obese subjects.Design Cross-sectional study with 85 female diabetics (BMI 18-43 kg/m2) measured with both DXA instruments.Results The regression lines for fat tissue mass (FTM), FAT% and total body bone mineral content (TBMC), but not lean tissue mass (LTM), were different from the line of identity (P < 0.01). However, the relationships were high (r2 > 0.95), and the corresponding SEE%'s were low (0.8-4.8%), and were independent of BMI. FTM and FAT% measured by the QDR-2000 were 10% higher, and LTM and TBMC 6% lower, than by DPX (P < 0.001).Conclusions There were lack of agreements between total body composition results by DPX Lunar, and QDR-2000 Hologic Inc. Individual results on the two systems cannot be directly compared. Standardization of body composition measurements by DXA is strongly needed.
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Differences in intra- and inter-manufacturer DXA estimates are small.
“Studies have shown that the differences in intraand inter-manufacturer estimates are small (11,14 -16).”
From Comparison of Body Composition Methods in Obese African‐American Women (2006) · cites this paper as [14]
At least two studies, one using QDR 2000, have shown QDR overestimates Lunar.
“However, at least two studies (14,35), one of which was conducted with the QDR 2000 (14), have shown that the QDR overestimates Lunar.”
From Comparison of Body Composition Methods in Obese African‐American Women (2006) · cites this paper as [14]
Cites
STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT
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Validation of body composition by dual energy X‐ray absorptiometry (DEXA)
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Body-composition assessment via air-displacement plethysmography in adults and children: a review
Fields, D. A., Goran, M. I., & McCrory, M. A. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/75.3.453 · Cited by 638 · see citing works
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“In the past, it has repeatedly been shown that individual results from Hologic and GE Lunar systems cannot be directly compared [6,7].”
BackgroundComparison of Body Composition Methods in Obese African‐American Women
Newton, R. L., Alfonso, A., York‐Crowe, E., Walden, H., White, M. A., Ryan, D., & Williamson, D. A. (2006) · Obesity · doi:10.1038/oby.2006.55 · Cited by 27 · see citing works
Yang, Y., Zhu, W. J., & Paton, N. I. (2004) · Antiviral Therapy · doi:10.1177/135965350400900516 · Cited by 15 · see citing works
- Authors
- Kistorp, C., & Svendsen, O.
- Venue
- European Journal of Clinical Nutrition
- Published
- 1997-07-01
- Volume
- 51
- Issue
- 7
- Pages
- 449-454
- ISSN
- 0954-3007 (ISSN-L)
- 1476-5640
- OpenAlex
- W2322668636
- Cited by
- 38
- References
- 5
- Citations by year
- 2024: 1 · 2020: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2012: 1
- FWCI
- 1.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
- Keywords
- body composition, dual-energy X-ray absorptiometry, instrument agreement, measurement standardization, type 2 diabetes, women, fat mass, body fat percentage, lean body mass, bone mineral content, obesity, lean subjects
- MeSH terms
- Adolescent, Aged, Body Composition, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Humans, Middle Aged, Reproducibility of Results, Absorptiometry, Photon, Bone Density
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