The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Effect of consumption of a ready-to-eat breakfast cereal containing inulin on the intestinal milieu and blood lipids in healthy male volunteers
Abstract
Objective To investigate the effect of a breakfast cereal containing inulin on blood lipids and colonic ecosystem in normolipidemic young men. Setting Department of Food Science and Microbiology,University of Milan, Italy. Subjects Twelve healthy male volunteers, age 23.3 +/- 0.5 y, body mass index (BMI) 25.7 +/- 1.2 kg/m2 (mean +/- s.e.m.). Interventions Subjects consumed daily, for three periods of four weeks, 50 g of a rice-based ready-to-eat cereal (placebo) and the same cereal containing 18% inulin (test) in substitution of their habitual breakfast, then returned to the habitual diet (wash-out). They followed no other dietary restrictions. Results No changes in body weight, dietary habits, faecal and bile acid output, faecal short-chain fatty acid (SCFA) and faecal pH, were observed at the end of each period, whereas plasma total cholesterol and triacylglycerols significantly decreased at the end of test period by 7.9 +/- 5.4 (P Conclusions Inulin seems to have a lipid lowering potential in normolipidemic men possibly mediated by mechanisms related to colonic fermentation.
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“Effects that are seen in these cases may, along with a reduction of the amount of glycaemic CHO ingested, be due to the production of short-chain fatty acids during colonic fermentation (Brighenti et al. 1999).”
From Glycaemic index methodology (2005) · cites this paper as Brighenti et al. 1999
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Metadata
- Authors
- Brighenti, F., Casiraghi, M., Canzi, E., & Ferrari, A.
- Affiliations
- University of Milan (IT)
- Corresponding author
- Brighenti, F
- ORCID
- Brighenti, F
- Venue
- European Journal of Clinical Nutrition
- Published
- 1999-09-01
- Volume
- 53
- Issue
- 9
- Pages
- 726-733
- ISSN
- 0954-3007 (ISSN-L)
- 1476-5640
- OpenAlex
- W2001862498
- Cited by
- 204
- References
- 24
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 6 · 2020: 6 · 2019: 6 · 2018: 9 · 2017: 11 · 2016: 8 · 2015: 10 · 2014: 12 · 2013: 6 · 2012: 14
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
- Keywords
- inulin, breakfast cereals, serum lipids, serum cholesterol, triglycerides, colonic fermentation, gut microbiota, Bifidobacterium, short-chain fatty acids, bile acids, hydrogen breath test, glucose tolerance, dietary fiber
- MeSH terms
- Adult, Analysis of Variance, Bile Acids and Salts, Energy Intake, Edible Grain, Colon, Feces, Female, Fermentation, Glucose Tolerance Test, Humans, Intestinal Mucosa, Intestines, Inulin, Italy, Lipids, Male
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