Protein and amino acid requirements in the elderly
Abstract
Estimates of protein and amino acid requirements in this paper are proposed for healthy elderly people. The estimate of protein requirement was based on nitrogen (N) balance, as well as functional indicators such as immune function or muscle strength. Data suggest that the protein requirement for nitrogen equilibrium in the elderly, is greater than 0.8 gm/kg body weight/day. There do not appear to be any adverse consequences with protein intakes that are about 1 gm/kg body weight/day. The tentative recommendation in this paper is higher than the current mean recommended intake of protein (FAO/WHO/UNU, 1985). However, because of methodological difficulties, the data does not allow for a confident prediction of what the exact level of protein intake should be. Further studies are needed to come to a firm conclusion on the exact protein requirement. Indispensable amino acid requirements based on nitrogen balance data, in the elderly, are fragmentary and conflicting. These requirements can alternatively be based on obligatory nitrogen loss, for which data is available in the elderly. The overlap of the obligatory nitrogen loss between the young and the elderly, suggest that the amino acid requirement based on this technique is similar in young and elderly individuals. Tracer based techniques measuring amino acid balance at different amino acid intakes, also support the view that there are no differences in the amino acid requirements between young and elderly people. In general, these amino acid requirement studies have been performed in healthy USA subjects, and data is needed to know if these estimates can be extended to populations from other, less-developed countries.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Physical activity during hospitalization and in posthospitalization rehabilitation sessions has reported benefits.
“There is no global standard or recommendation, but physical activity during hospitalization and in posthospitalization rehabilitation sessions has reported benefits.1e3,5e10, 69,70,149e152”
From Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group (2013) · cites this paper as [7]
Cites
Exogenous amino acids stimulate net muscle protein synthesis in the elderly.
Volpi, E., Ferrando, A. A., Yeckel, C. W., Tipton, K. D., & Wolfe, R. R. (1998) · Journal of Clinical Investigation · doi:10.1172/jci939 · Cited by 390 · see citing works
Castaneda, C., Charnley, J., Evans, W., & Crim, M. (1995) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.1.30 · Cited by 290 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., et al. (2013) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.05.021 · Cited by 2,553 · see citing works
Position of the Academy of Nutrition and Dietetics: Vegetarian Diets
Melina, V., Craig, W., & Levin, S. (2016) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2016.09.025 · Cited by 1,360 · see citing works
Meta-analysis of nitrogen balance studies for estimating protein requirements in healthy adults
Rand, W. M., Pellett, P. L., & Young, V. R. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.1.109 · Cited by 506 · see citing works
Chernoff, R. (2004) · Journal of the American College of Nutrition · doi:10.1080/07315724.2004.10719434 · Cited by 133 · see citing works
An adaptive metabolic demand model for protein and amino acid requirements
Millward, D. J. (2003) · British Journal of Nutrition · doi:10.1079/bjn2003924 · Cited by 100 · see citing works
- Authors
- Kurpad, A., & Vaz, M.
- Affiliations
- St.John's Medical College Hospital (IN)
- ORCID
- Vaz, M
- Venue
- European Journal of Clinical Nutrition
- Published
- 2000-06-01
- Volume
- 54
- Issue
- S3
- Pages
- S131-S142
- ISSN
- 0954-3007 (ISSN-L)
- 1476-5640
- OpenAlex
- W1992023478
- Cited by
- 70
- References
- 2
- Citations by year
- 2024: 1 · 2023: 3 · 2022: 2 · 2020: 1 · 2019: 1 · 2018: 4 · 2017: 1 · 2016: 8 · 2015: 1 · 2014: 1 · 2013: 5 · 2012: 4
- FWCI
- 0.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Keywords
- protein requirements, amino acid requirements, older adults, nitrogen balance, immune function, muscle strength, RDA, essential amino acids
- MeSH terms
- Aged, Aging, Amino Acids, Dietary Proteins, Health Status, Humans, Nitrogen, Nutritional Requirements, Proteins, Nutrition Assessment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review