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MK2‐induced tristetraprolin:14‐3‐3 complexes prevent stress granule association and ARE‐mRNA decay

Stoecklin, Georg, Stubbs, Tiffany, Kedersha, Nancy, Wax, Stephen, Rigby, William FC, Blackwell, T Keith, Anderson, Paul·2004·The EMBO Journal
DOI 10.1038/sj.emboj.7600163
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  • Phosphorylation of ZFP36 by MK2 diminishes its mRNA-destabilizing activity.

    “For instance, phosphorylation of ZFP36 by MK2, a kinase downstream of p38 MAPK, has been found to diminish its mRNA-destabilizing activity [26].”

    From Triciribine Engages ZFP36L1 and HuR to Stabilize LDLR mRNA (2020) · cites this paper as [26]

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Research works printed but not linked: 38

  1. Anderson P, Kedersha N (2002) Stressful initiations. J Cell Sci 115: 3227–3234 · DOI
  2. Anderson P, Phillips K, Stoecklin G, Kedersha N (2004) Post‐transcriptional regulation of pro‐inflammatory proteins. J Leuk Biol, (in press) · DOI
  3. Blackshear PJ (2002) Tristetraprolin and other CCCH tandem zinc‐finger proteins in the regulation of mRNA turnover. Biochem Soc Trans 30: 945–952 · DOI
  4. Brooks SA, Connolly JE, Diegel RJ, Fava RA, Rigby WF (2002) Analysis of the function, expression, and subcellular distribution of human tristetraprolin. Arthritis Rheum 46: 1362–1370 · DOI
  5. Carballo E, Cao H, Lai WS, Kennington EA, Campbell D, Blackshear PJ (2001) Decreased sensitivity of tristetraprolin‐deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway. J Biol Chem 276: 42580–42587 · DOI
  6. Carballo E, Lai WS, Blackshear PJ (1998) Feedback inhibition of macrophage tumor necrosis factor‐alpha production by tristetraprolin. Science 281: 1001–1005 · DOI
  7. Chen CY, Gherzi R, Ong SE, Chan EL, Raijmakers R, Pruijn GJ, Stoecklin G, Moroni C, Mann M, Karin M (2001) AU binding proteins recruit the exosome to degrade ARE‐containing mRNAs. Cell 107: 451–464 · DOI · Paper page
  8. Chrestensen CA, Schroeder MJ, Shabanowitz J, Hunt DF, Pelo JW, Worthington MT, Sturgill TW (2004) MK2 phosphorylates tristetraprolin on in vivo sites including S178, a site required for 14‐3‐3 binding. J Biol Chem, (in press) · DOI
  9. Civelli O, Vincent A, Maundrell K, Buri J, Scherrer K (1980) The translational repression of globin mRNA in free cytoplasmic ribonucleoprotein complexes. Eur J Biochem 107: 577–585 · DOI
  10. Clemens MJ (2001) Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis. Prog Mol Subcell Biol 27: 57–89 · DOI
  11. Fan XC, Steitz JA (1998) Overexpression of HuR, a nuclear‐cytoplasmic shuttling protein, increases the in vivo stability of ARE‐containing mRNAs. EMBO J 17: 3448–3460 · DOI · Paper page
  12. Gaestel M (2002) sHsp‐phosphorylation: enzymes, signaling pathways and functional implications. Prog Mol Subcell Biol 28: 151–169 · DOI
  13. Harding HP, Ron D (2002) Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes 51 (Suppl 3): S455–S461 · DOI
  14. Hinnebusch AG, Natarajan K (2002) Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress. Eukaryot Cell 1: 22–32 · DOI
  15. Johnson BA, Geha M, Blackwell TK (2000) Similar but distinct effects of the tristetraprolin/TIS11 immediate‐early proteins on cell survival. Oncogene 19: 1657–1664 · DOI
  16. Johnson BA, Stehn JR, Yaffe MB, Blackwell TK (2002) Cytoplasmic localization of tristetraprolin involves 14‐3‐3‐dependent and ‐independent mechanisms. J Biol Chem 277: 18029–18036 · DOI
  17. Kedersha N, Anderson P (2001) Stress granules: sites of mRNA triage that regulate mRNA stability and translatability. Biochem Soc Trans 30: 963–969 · DOI
  18. Kedersha N, Chen S, Gilks N, Li W, Miller IJ, Stahl J, Anderson P (2002) Evidence that ternary complex (eIF2–GTP–tRNA(i)(Met))‐deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell 13: 195–210 · DOI
  19. Kedersha N, Cho MR, Li W, Yacono PW, Chen S, Gilks N, Golan DE, Anderson P (2000) Dynamic shuttling of TIA‐1 accompanies the recruitment of mRNA to mammalian stress granules. J Cell Biol 151: 1257–1268 · DOI
  20. Kedersha NL, Gupta M, Li W, Miller I, Anderson P (1999) RNA‐binding proteins TIA‐1 and TIAR link the phosphorylation of eIF‐2 alpha to the assembly of mammalian stress granules. J Cell Biol 147: 1431–1442 · DOI
  21. Lai WS, Carballo E, Strum JR, Kennington EA, Phillips RS, Blackshear PJ (1999) Evidence that tristetraprolin binds to AU‐rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol 19: 4311–4323 · DOI
  22. Mahtani KR, Brook M, Dean JL, Sully G, Saklatvala J, Clark AR (2001) Mitogen‐activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability. Mol Cell Biol 21: 6461–6469 · DOI
  23. Ming XF, Kaiser M, Moroni C (1998) c‐jun N‐terminal kinase is involved in AUUUA‐mediated interleukin‐3 mRNA turnover in mast cells. EMBO J 17: 6039–6048 · DOI
  24. Ming XF, Stoecklin G, Lu M, Looser R, Moroni C (2001) Parallel and independent regulation of interleukin‐3 mRNA turnover by phosphatidylinositol 3‐kinase and p38 mitogen‐activated protein kinase. Mol Cell Biol 21: 5778–5789 · DOI
  25. Nover L, Scharf KD, Neumann D (1989) Cytoplasmic heat shock granules are formed from precursor particles and are associated with a specific set of mRNAs. Mol Cell Biol 9: 1298–1308
  26. Peng SS, Chen CY, Xu N, Shyu AB (1998) RNA stabilization by the AU‐rich element binding protein, HuR, an ELAV protein. EMBO J 17: 3461–3470 · DOI
  27. Sheth U, Parker R (2003) Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300: 805–808 · DOI
  28. Stoecklin G, Colombi M, Raineri I, Leuenberger S, Mallaun M, Schmidlin M, Gross B, Lu M, Kitamura T, Moroni C (2002) Functional cloning of BRF1, a regulator of ARE‐dependent mRNA turnover. EMBO J 21: 4709–4718 · DOI
  29. Stoecklin G, Ming XF, Looser R, Moroni C (2000) Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin‐3 mRNA degradation pathway. Mol Cell Biol 20: 3753–3763 · DOI
  30. Stoecklin G, Stoeckle P, Lu M, Muehlemann O, Moroni C (2001) Cellular mutants define a common mRNA degradation pathway targeting cytokine AU‐rich elements. RNA 7: 1578–1588
  31. Taylor GA, Carballo E, Lee DM, Lai WS, Thompson MJ, Patel DD, Schenkman DI, Gilkeson GS, Broxmeyer HE, Haynes BF, Blackshear PJ (1996) A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity 4: 445–454 · DOI
  32. Taylor GA, Thompson MJ, Lai WS, Blackshear PJ (1995) Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen‐activated protein kinase in vitro. J Biol Chem 270: 13341–13347 · DOI
  33. Tzivion G, Avruch J (2002) 14‐3‐3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation. J Biol Chem 277: 3061–3064 · DOI
  34. Waskiewicz AJ, Johnson JC, Penn B, Mahalingam M, Kimball SR, Cooper JA (1999) Phosphorylation of the cap‐binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo. Mol Cell Biol 19: 1871–1880 · DOI
  35. Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Muller M, Gaestel M, Resch K, Holtmann H (1999) The p38 MAP kinase pathway signals for cytokine‐induced mRNA stabilization via MAP kinase‐activated protein kinase 2 and an AU‐rich region‐targeted mechanism. EMBO J 18: 4969–4980 · DOI
  36. Xu N, Loflin P, Chen CY, Shyu AB (1998) A broader role for AU‐rich element‐mediated mRNA turnover revealed by a new transcriptional pulse strategy. Nucleic Acids Res 26: 558–565 · DOI
  37. Yaffe MB, Rittinger K, Volinia S, Caron PR, Aitken A, Leffers H, Gamblin SJ, Smerdon SJ, Cantley LC (1997) The structural basis for 14‐3‐3:phosphopeptide binding specificity. Cell 91: 961–971 · DOI
  38. Zhu W, Brauchle MA, Di Padova F, Gram H, New L, Ono K, Downey JS, Han J (2001) Gene suppression by tristetraprolin and release by the p38 pathway. Am J Physiol Lung Cell Mol Physiol 281: L499–L508 · DOI

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Metadata

Authors
Stoecklin, G., Stubbs, T., Kedersha, N., Wax, S., Rigby, W. F., Blackwell, T. K., & Anderson, P.
Venue
The EMBO Journal
Publisher
Springer Science and Business Media LLC
Published
2004-03-11
Volume
23
Issue
6
Pages
1313-1324
ISSN
  • 0261-4189
  • 1460-2075
DOI
10.1038/sj.emboj.7600163
Cited by
448
References
1
Language
en
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