The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Reconstitution of a minimal mtDNA replisome in vitro
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Replication of animal mitochondrial DNA
Clayton, D. A. (1982) · Cell · doi:10.1016/0092-8674(82)90049-6 · Cited by 1,226
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
Doublié, S., Tabor, S., Long, A. M., Richardson, C. C., & Ellenberger, T. (1998) · Nature · doi:10.1038/34593 · Cited by 1,175
MITOCHONDRIAL DNA MAINTENANCE IN VERTEBRATES
Shadel, G. S., & Clayton, D. A. (1997) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.66.1.409 · Cited by 1,065
Spelbrink, J. N., Li, F.-Y., Tiranti, V., Nikali, K., Yuan, Q.-P., Tariq, M., Wanrooij, S., Garrido, N., Comi, G., Morandi, L., et al. (2001) · Nature Genetics · doi:10.1038/90058 · Cited by 882
ESCHERICHIA COLI SINGLE-STRANDED DNA-BINDING PROTEIN: Multiple DNA-Binding Modes and Cooperativities
Lohman, T. M., & Ferrari, M. E. (1994) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.63.070194.002523 · Cited by 606
Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA
Falkenberg, M., Gaspari, M., Rantanen, A., Trifunovic, A., Larsson, N.-G., & Gustafsson, C. M. (2002) · Nature Genetics · doi:10.1038/ng909 · Cited by 598 · cited 1×
“…of POLg, we co-infected Sf9 cells with recombinant baculoviruses encoding His6-tagged versions of POLg subunits A and B. Whole-cell extract was generated and recombinant POLg was purified on Ni2þ -agarose, as previously described for the human mitochondrial RNA polymerase (Falkenberg et al, 2002).”
MethodSelf-citationReplication and Transcription of Mammalian Mitochondrial Dna
Fernández‐Silva, P., Enriquez, J. A., & Montoya, J. (2003) · Experimental Physiology · doi:10.1113/eph8802514 · Cited by 433
Coupled Leading- and Lagging-Strand Synthesis of Mammalian Mitochondrial DNA
Holt, I. J., Lorimer, H. E., & Jacobs, H. T. (2000) · Cell · doi:10.1016/s0092-8674(00)80688-1 · Cited by 417
Priming of human mitochondrial DNA replication occurs at the light-strand promoter.
Chang, D. D., & Clayton, D. A. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.2.351 · Cited by 340
Replisome-Mediated DNA Replication
Benkovic, S. J., Valentine, A. M., & Salinas, F. (2001) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.70.1.181 · Cited by 328
Cited by
Insect Mitochondrial Genomics: Implications for Evolution and Phylogeny
Cameron, S. L. (2014) · Annual Review of Entomology · doi:10.1146/annurev-ento-011613-162007 · Cited by 1,443
Mitochondrial DNA mutations and human disease
Tuppen, H. A. L., Blakely, E. L., Turnbull, D. M., & Taylor, R. W. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2009.09.005 · Cited by 676
“Core components of the mitochondrial replisome include POLG, consisting of a catalytic subunit with 5 ′– 3 ′ exonuclease activity (PolgA) and a processivity subunit (PolgB), Twinkle, with 5 ′– 3 ′ DNA helicase activity, and mt-SSB [30].”
BackgroundER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells
Lewis, S. C., Uchiyama, L. F., & Nunnari, J. (2016) · Science · doi:10.1126/science.aaf5549 · Cited by 673
Mitochondrial diseases: the contribution of organelle stress responses to pathology
Suomalainen, A., & Battersby, B. J. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.66 · Cited by 505
Mitochondria at the crossroads of health and disease
Suomalainen, A., & Nunnari, J. (2024) · Cell · doi:10.1016/j.cell.2024.04.037 · Cited by 478
Metadata
- Authors
- Korhonen, J. A., Pham, X. H., Pellegrini, M., & Falkenberg, M.
- Venue
- The EMBO Journal
- Published
- 2004-05-27
- Volume
- 23
- Issue
- 12
- Pages
- 2423-2429
- ISSN
- 0261-4189 (ISSN-L)
- 1460-2075
- OpenAlex
- W2059453827
- Cited by
- 403
- References
- 29
- FWCI
- 4.81
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Reconstitution of a minimal mtDNA replisome in vitro. https://app.cochat.ai/papers/10.1038/sj.emboj.7600257
- The paper
- Korhonen, J. A., Pham, X. H., Pellegrini, M., & Falkenberg, M. (2004). Reconstitution of a minimal mtDNA replisome in vitro. The EMBO Journal. https://doi.org/10.1038/sj.emboj.7600257
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.