Mediators of endoplasmic reticulum stress-induced apoptosis

Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+

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Signal transduction by the JNK group of MAP kinases

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XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Yoshida, H., Matsui, T., Yamamoto, A., Okada, T., & Mori, K. (2001) · Cell · doi:10.1016/s0092-8674(01)00611-0 · Cited by 4,054

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Wei, M. C., Zong, W.-X., Cheng, E. H.-Y., Lindsten, T., Panoutsakopoulou, V., Ross, A. J., Roth, K. A., MacGregor, G. R., Thompson, C. B., & Korsmeyer, S. J. (2001) · Science · doi:10.1126/science.1059108 · Cited by 3,988

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

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An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

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THE MAMMALIAN UNFOLDED PROTEIN RESPONSE

Schröder, M., & Kaufman, R. J. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.074134 · Cited by 3,099

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.

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Inhibition of glioma growth by minocycline is mediated through endoplasmic reticulum stress-induced apoptosis and autophagic cell death

Liu, W.-T., Huang, C.-Y., Lu, I.-C., & Gean, P. (2013) · Neuro-Oncology · doi:10.1093/neuonc/not073 · Cited by 43

Ectonucleoside Triphosphate Diphosphohydrolase Type 5 (Entpd5)-Deficient Mice Develop Progressive Hepatopathy, Hepatocellular Tumors, and Spermatogenic Arrest

Read, R. W., Hansen, G. M., Kramer, J. A., Finch, R. A., Li, L., & Vogel, P. (2009) · Veterinary Pathology · doi:10.1354/vp.08-vp-0201-r-am · Cited by 43

High fat-diet and saturated fatty acid palmitate inhibits IGF-1 function in chondrocytes

Nazli, S. A., Loeser, R. F., Chubinskaya, S., Willey, J. S., & Yammani, R. R. (2017) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2017.05.011 · Cited by 43

Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway

Restall, I. J., Cseh, O., Richards, L. M., Pugh, T. J., Luchman, H. A., & Weiss, S. (2020) · Cancer Research · doi:10.1158/0008-5472.can-19-3923 · Cited by 42

Emerging perspectives on mitochondrial dysfunctioning and inflammation in epileptogenesis

Singh, S., & Singh, T. G. (2021) · Inflammation Research · doi:10.1007/s00011-021-01511-9 · Cited by 43

Attenuation of malignant phenotypes of breast cancer cells through eIF2α-mediated downregulation of Rac1 signaling

Hamamura, K., Minami, K., Tanjung, N., Wan, Q., Koizumi, M., Matsuura∥, N., NA, S., & Yokota, H. (2014) · International Journal of Oncology · doi:10.3892/ijo.2014.2366 · Cited by 42

Autophagy in the brains of young patients with poorly controlled T1DM and fatal diabetic ketoacidosis

Hoffman, W. H., Shacka, J. J., & Andjelkovic, A. V. (2011) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2011.10.007 · Cited by 42

Tributyltin-induced endoplasmic reticulum stress and its Ca2+-mediated mechanism

Isomura, M., Kotake, Y., Masuda, K., Miyara, M., Okuda, K., Samizo, S., Sanoh, S., Hosoi, T., Ozawa, K., & Ohta, S. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2013.05.026 · Cited by 42

Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating the unfolded protein response pathway

Bustany, S., Cahu, J., Guardiola, P., & Sola, B. (2015) · BMC Cancer · doi:10.1186/s12885-015-1240-y · Cited by 44

Ganglioside GD3 as a Raft Component in Cell Death Regulation

Sorice, M., Garofalo, T., Misasi, R., Manganelli, V., Vona, R., & Malorni, W. (2012) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152012800228670 · Cited by 42

Proteasome Inhibition Represses Unfolded Protein Response and Nox4, Sensitizing Vascular Cells to Endoplasmic Reticulum Stress-Induced Death

Amanso, A. M., Debbas, V., & Laurindo, F. R. M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0014591 · Cited by 42

cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice

Ma, H., Butler, M. R., Thapa, A., Belcher, J., Yang, F., Baehr, W., Biel, M., Michalakis, S., & Ding, X. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.641159 · Cited by 42

Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress

Yuniati, L., van der Meer, L. T., Tijchon, E. J. H., Schenau, D. V. I., van Emst, L., Levers, M., Palit, S. A. L., Rodenbach, C., Poelmans, G., Hoogerbrugge, P. M., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.6519 · Cited by 43

Propofol attenuates H2O2-induced oxidative stress and apoptosis via the mitochondria- and ER-medicated pathways in neonatal rat cardiomyocytes

Liu, X., Cao, L., Li, T., Chen, L., Yu, Y., Huang, W., Liu, L., & Tan, X. (2017) · APOPTOSIS · doi:10.1007/s10495-017-1349-3 · Cited by 42

G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells

Vo, D.-K. H., Hartig, R., Weinert, S., Haybaeck, J., & Naß, N. (2019) · Biomolecules · doi:10.3390/biom9090503 · Cited by 42

Proteostasis in the Endoplasmic Reticulum: Road to Cure

Nam, S. M., & Jeon, Y. J. (2019) · Cancers · doi:10.3390/cancers11111793 · Cited by 45

Sestrin2 protects dendritic cells against endoplasmic reticulum stress-related apoptosis induced by high mobility group box-1 protein

Wang, L., Zhu, X., Luo, Y., Wu, Y., Dong, N., Tong, Y., & Yao, Y.-M. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2324-4 · Cited by 44

Mechanism of inositol-requiring enzyme 1-alpha inhibition in endoplasmic reticulum stress and apoptosis in ovarian cancer cells

Barez, S. R., Atar, A., & Aghaei, M. (2020) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-020-00562-7 · Cited by 39

Oncogenic BRAF, endoplasmic reticulum stress, and autophagy: Crosstalk and therapeutic targets in cutaneous melanoma

Rather, R. A., Bhagat, M., & Singh, S. K. (2020) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2020.108321 · Cited by 43

The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation

Shi, J., Li, Z., Xu, R., Zhang, J., Zhou, Q., Gao, R., Lu, H., Lan, Y., Zhao, K., He, H., et al. (2021) · Journal of Virology · doi:10.1128/jvi.01695-21 · Cited by 42

Aldehyde Dehydrogenase-2 Deficiency Aggravates Cardiac Dysfunction Elicited by Endoplasmic Reticulum Stress Induction

Liao, J., Sun, A., Xie, Y., Isse, T., Kawamoto, T., Zou, Y., & Ge, J. (2012) · Molecular Medicine · doi:10.2119/molmed.2011.00466 · Cited by 42

Nerve growth factor blocks thapsigargin‐induced apoptosis at the level of the mitochondrion via regulation of Bim

Szegezdi, É., Herbert, K. R., Kavanagh, E. T., Samali, A., & Gorman, A. M. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00268.x · Cited by 41

IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development

Han, X., Zhou, J., Zhang, P., Song, F., Jiang, R., Li, M., Xia, F., & Guo, F. (2013) · Cellular Signalling · doi:10.1016/j.cellsig.2013.06.011 · Cited by 41

C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis

Rahman, K., Liu, Y., Kumar, P., Smith, T., Thorn, N. E., Farris, A. B., & Anania, F. A. (2016) · Laboratory Investigation · doi:10.1038/labinvest.2016.61 · Cited by 39

Endoplasmic reticulum stress-mediated cell death in cardiovascular disease

An, Y., Wang, X., Guan, X., Yuan, P., Liu, Y., Wei, L., Wang, F., & Qi, X. (2024) · Cell Stress and Chaperones · doi:10.1016/j.cstres.2023.12.003 · Cited by 46

Attenuation of CHOP-mediated Myocardial Apoptosis in Pressure-overloaded Dominant Negative p38α Mitogen-activated Protein Kinase Mice

Sari, F. R., Widyantoro, B., Thandavarayan, R. A., Harima, M., Lakshmanan, A. P., Zhang, S., Muslin, A. J., Suzuki, K., Kodama, M., & Watanabe, K. (2011) · Cellular Physiology and Biochemistry · doi:10.1159/000329970 · Cited by 41

Progesterone production is affected by unfolded protein response (UPR) signaling during the luteal phase in mice

Park, H., Park, S.-J., Koo, D., Lee, S., Kong, I., Ryoo, J., Park, Y.-I., Chang, K., & Lee, D. (2014) · Life Sciences · doi:10.1016/j.lfs.2014.07.033 · Cited by 41

Endoplasmic reticulum stress and unfolded protein response are involved in paediatric inflammatory bowel disease

Negroni, A., Prete, E., Vitali, R., Cesi, V., Aloi, M., Civitelli, F. S., Cucchiara, S., & Stronati, L. (2014) · Digestive and Liver Disease · doi:10.1016/j.dld.2014.05.013 · Cited by 43

Age-Enhanced Endoplasmic Reticulum Stress Contributes to Increased Atg9A Inhibition of STING-Mediated IFN-β Production during Streptococcus pneumoniae Infection

Mitzel, D., Lowry, V. K., Shirali, A. C., Liu, Y., & Stout-Delgado, H. W. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1303090 · Cited by 42

Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticum

Hosen, M. J., Coucke, P. J., Saux, O. L., Paepe, A. D., & Vanakker, O. M. (2014) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-9-66 · Cited by 41

Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis

Zhang, B., Han, H., Fu, S., Yang, P., Gu, Z., Zhou, Q., & Cao, Z. (2016) · Biochemical Pharmacology · doi:10.1016/j.bcp.2016.01.002 · Cited by 41

Grape seed proanthocyanidin protects liver against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress

Xu, Z. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i24.7468 · Cited by 41

Non-thermal gas plasma-induced endoplasmic reticulum stress mediates apoptosis in human colon cancer cells

Kumara, M. H. S. R., Piao, M. J., Kang, K. A., Ryu, Y. S., Park, J. E., Shilnikova, K., Jo, J. O., Mok, Y. S., Shin, J. H., Park, Y., et al. (2016) · Oncology Reports · doi:10.3892/or.2016.5038 · Cited by 41

Rosmarinic acid and siRNA combined therapy represses Hsp27 (HSPB1) expression and induces apoptosis in human glioma cells

Şengelen, A., & Uçar, E. Ö. (2018) · Cell Stress and Chaperones · doi:10.1007/s12192-018-0896-z · Cited by 41

(−)‐ Epigallocatechin‐3‐gallate induces GRP78 accumulation in the ER and shifts mesothelioma constitutive UPR into proapoptotic ER stress

Martinotti, S., Ranzato, E., & Burlando, B. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26631 · Cited by 41

Depletion of Microglia Attenuates Dendritic Spine Loss and Neuronal Apoptosis in the Acute Stage of Moderate Traumatic Brain Injury in Mice

Wang, C., Zhao, C., Liu, W., Huang, X., Deng, Y., Jiang, J., & Li, W. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2019.6460 · Cited by 40

miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress

Chi, L., Jiao, D., Nan, G., Yuan, H., Shen, J., & Gao, Y. (2019) · Acta Histochemica · doi:10.1016/j.acthis.2019.08.005 · Cited by 42

Roles of ERK/Akt signals in mitochondria-dependent and endoplasmic reticulum stress-triggered neuronal cell apoptosis induced by 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a major active metabolite of bisphenol A

Huang, C.-F., Liu, S., Su, C., Fang, K., Yen, C., Yang, C., Tang, F., Liu, J., Wu, C.-C., Lee, K.-I., et al. (2021) · Toxicology · doi:10.1016/j.tox.2021.152764 · Cited by 42

Requirements for Designing an Effective Metallic Nanoparticle (NP)-Boosted Radiation Therapy (RT)

Tremi, I., Spyratou, E., Souli, M., EFSTATHOPOULOS, E. P., Μakropoulou, Μ., Georgakilas, A. G., & Sihver, L. (2021) · Cancers · doi:10.3390/cancers13133185 · Cited by 42

ERdj5 Sensitizes Neuroblastoma Cells to Endoplasmic Reticulum Stress-induced Apoptosis

Thomas, C. G., & Spyrou, G. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m806189200 · Cited by 41

Ferulic Acid as a Protective Antioxidant of Human Intestinal Epithelial Cells

Hwang, H.-J., Lee, S. R., Yoon, J.-G., Moon, H.-R., Zhang, J., Park, E., Yoon, S.-I., & Cho, J. A. (2022) · Antioxidants · doi:10.3390/antiox11081448 · Cited by 41

Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells

Trondl, R., Flocke, L. S., Kowol, C. R., Heffeter, P., Jungwirth, U., Mair, G. E., Steinborn, R., Enyedy, É. A., Jakupec, M. A., Berger, W., et al. (2014) · Molecular Pharmacology · doi:10.1124/mol.113.090605 · Cited by 40

Advanced oxidation protein products induce apoptosis in podocytes through induction of endoplasmic reticulum stress

Rong, G., Tang, X., Guo, T., Duan, N., Wang, Y., Yang, L., Zhang, J., & Liang, X. (2015) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-015-0424-x · Cited by 40

The Role of the Protein Quality Control System in SBMA

Rusmini, P., Crippa, V., Cristofani, R., Rinaldi, C., Cicardi, M. E., Galbiati, M., Carra, S., Malik, B. A., Greensmith, L., & Poletti, A. (2015) · Journal of Molecular Neuroscience · doi:10.1007/s12031-015-0675-6 · Cited by 41

Protein disulfide isomerase inhibition synergistically enhances the efficacy of sorafenib for hepatocellular carcinoma

Won, J., Yu, S. J., Hwang, C. Y., Cho, S., Park, S., Kim, K., Choi, W., Cho, H., Cho, E. J., Lee, J., et al. (2017) · Hepatology · doi:10.1002/hep.29237 · Cited by 41

Hyperosmotic stress promotes endoplasmic reticulum stress-dependent apoptosis in adult rat cardiac myocytes

Burgos, J. I., Morell, M., Mariángelo, J. I. E., & Petroff, M. V. (2019) · APOPTOSIS · doi:10.1007/s10495-019-01558-4 · Cited by 40

The Rational Design and Biological Mechanisms of Nanoradiosensitizers

Sun, H., Wang, X., & Zhai, S. (2020) · Nanomaterials · doi:10.3390/nano10030504 · Cited by 41

The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models

Parakh, S., Shadfar, S., Perri, E. R., Ragagnin, A., Piattoni, C. V., Bollati‐Fogolín, M., Yuan, K. C., Shahheydari, H., Don, E. K., Thomas, C. J., et al. (2020) · iScience · doi:10.1016/j.isci.2020.101097 · Cited by 40

Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress

Xu, K., Chai, B., Zhang, K., Xiong, J., Zhu, Y., Xu, J., An, N., Xia, W., Ji, H., Wu, Y., et al. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/8586314 · Cited by 40

PPARβ/δ Agonist Provides Neuroprotection by Suppression of IRE1α–Caspase-12-Mediated Endoplasmic Reticulum Stress Pathway in the Rotenone Rat Model of Parkinson’s Disease

Tong, Q., Wu, L., Gao, Q., Ou, Z., Zhu, D., & Zhang, Y. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9309-9 · Cited by 40

Lysosome Dysfunction Enhances Oxidative Stress‐Induced Apoptosis through Ubiquitinated Protein Accumulation in Hela Cells

Yu, C., Huang, X., Xu, Y., Li, H., Su, J., Zhong, J., Kang, J., Liu, Y., & Sun, L. (2012) · The Anatomical Record · doi:10.1002/ar.22612 · Cited by 40

ER stress and genomic instability induced by gamma radiation in mice primary cultured glial cells

Chatterjee, J., Nairy, R. K., Langhnoja, J., Tripathi, A., Patil, R. K., Pillai, P. P., & Mustak, M. S. (2018) · Metabolic Brain Disease · doi:10.1007/s11011-018-0183-9 · Cited by 39

CRELD2 Is a Novel LRP1 Chaperone That Regulates Noncanonical WNT Signaling in Skeletal Development

Dennis, E. P., Edwards, S. M., Jackson, R. M., Hartley, C. L., Tsompani, D., Capulli, M., Teti, A. M., Boot-Handford, R., Young, D. A., Piróg, K. A., et al. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4010 · Cited by 38

The critical role of endoplasmic reticulum stress and the stimulator of interferon genes (STING) pathway in kidney fibrosis

Andrade-Silva, M., Dhillon, P., Sánchez‐Navarro, A., Mukhi, D., Hu, H., Kolligundla, L. P., Bergeson, A., Abedini, A., Levinsohn, J. L., Dumoulin, B., et al. (2024) · Kidney International · doi:10.1016/j.kint.2024.10.021 · Cited by 39

Cordycepin Induces Apoptosis of CGTH W-2 Thyroid Carcinoma Cells through the Calcium−Calpain−Caspase 7-PARP Pathway

Chen, Y., Chen, Y., Lin, Y., Huang, S.-H., & Wang, S. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf1028976 · Cited by 39

The Endoplasmic Reticulum Stress Transducer BBF2H7 Suppresses Apoptosis by Activating the ATF5-MCL1 Pathway in Growth Plate Cartilage

Izumi, S., Saito, A., Kanemoto, S., Kawasaki, N., Asada, R., Iwamoto, H., Oki, M., Miyagi, H., Ochi, M., & Imaizumi, K. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.373746 · Cited by 39

Endoplasmic reticulum stress in spinal and bulbar muscular atrophy: a potential target for therapy

Montague-Cardoso, K., Malik, B. A., Gray, A. L., Spada, A. R. L., Hanna, M. G., Szabadkai, G., & Greensmith, L. (2014) · Brain · doi:10.1093/brain/awu114 · Cited by 39

Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis

Yu, S. J., Yoon, J., Lee, J., Myung, S. J., Jang, E.-S., Kwak, M., Cho, E. J., Jang, J., Kim, Y. J., & Lee, H.-S. (2011) · Acta Pharmacologica Sinica · doi:10.1038/aps.2011.24 · Cited by 39

New insights into the unfolded protein response in stem cells

Yang, Y., Cheung, H., Tu, J., Miu, K.-K., & Chan, W. (2016) · Oncotarget · doi:10.18632/oncotarget.9833 · Cited by 41

EspC, an Autotransporter Protein Secreted by Enteropathogenic Escherichia coli, Causes Apoptosis and Necrosis through Caspase and Calpain Activation, Including Direct Procaspase-3 Cleavage

Serapio-Palacios, A., & Navarro-García, F. (2016) · mBio · doi:10.1128/mbio.00479-16 · Cited by 36

High expression of active ATF6 aggravates endoplasmic reticulum stress‑induced vascular endothelial cell apoptosis through the mitochondrial apoptotic pathway

Huang, J., Wan, L., Lu, H., & Li, X. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.8658 · Cited by 39

Endoplasmic reticulum stress is involved in the T‐2 toxin‐induced apoptosis in goat endometrium epithelial cells

Yi, Y., Zhao, F., Wang, N., Liu, H., Yu, L., Wang, A., & Jin, Y. (2018) · Journal of Applied Toxicology · doi:10.1002/jat.3655 · Cited by 39

MicroRNA-24 promotes pancreatic beta cells toward dedifferentiation to avoid endoplasmic reticulum stress-induced apoptosis

Zhu, Y., Sun, Y., Zhou, Y., Zhang, Y., Zhang, T., Li, Y., You, W., Chang, X., Li, Y., & Han, X. (2019) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjz004 · Cited by 38

Peroxisome proliferator‐activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging

Gill, J. F., Delezie, J., Santos, G., McGuirk, S., Schnyder, S., Frank, S., Rausch, M., St‐Pierre, J., & Handschin, C. (2019) · Aging Cell · doi:10.1111/acel.12993 · Cited by 41

Induction of Endoplasmic Reticulum Stress Pathway by Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Activation of PERK/p-eIF2α/ATF4 and IRE1α

Nesran, Z. N. M., Shafie, N. H., Ishak, A. H., Norhaizan, M. E., Ismail, A., & Tohid, S. F. M. (2019) · BioMed Research International · doi:10.1155/2019/3480569 · Cited by 39

Natural polyphenols prevent indomethacin-induced and diclofenac-induced Caco-2 cell death by reducing endoplasmic reticulum stress regardless of their direct reactive oxygen species scavenging capacity

Boonyong, C., Vardhanabhuti, N., & Jianmongkol, S. (2020) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.13227 · Cited by 39

Targeted Inhibition of P4HB Promotes Cell Sensitivity to Gemcitabine in Urothelial Carcinoma of the Bladder

Wang, X., Bai, Y., Zhang, F., Yang, Y., Feng, D., Li, A., Yang, Z., Li, D., Tang, Y., Wei, X., et al. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s267734 · Cited by 39

Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor

Gebert, M., Sobolewska, A., Bartoszewska, S., Cabaj, A., Crossman, D. K., Króliczewski, J., Madanecki, P., Dąbrowski, M., Collawn, J. F., & Bartoszewski, R. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03952-1 · Cited by 43

The Antiviral Effects of 2-Deoxy-D-glucose (2-DG), a Dual D-Glucose and D-Mannose Mimetic, against SARS-CoV-2 and Other Highly Pathogenic Viruses

Pająk, B., Zielinski, R. J., Manning, J. T., Matejin, S., Paessler, S., Fokt, I., Emmett, M. R., & Priebe, W. (2022) · Molecules · doi:10.3390/molecules27185928 · Cited by 40

New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory Pathways

Martelli, A., Omrani, M., Zarghooni, M., Citi, V., Brogi, S., Calderone, V., Sureda, A., Lorzadeh, S., Rosa, S. C. D. S., Grabarek, B. O., et al. (2022) · Cancers · doi:10.3390/cancers14235839 · Cited by 40

Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress response

Ou, L., Wu, Y., Ip, C. C. Y., Meng, X., Hsu, Y.-C., & Ip, M. M. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m700465-jlr200 · Cited by 39

The Unhydrolyzable Fenretinide Analogue 4-Hydroxybenzylretinone Induces the Proapoptotic Genes GADD153 ( CHOP ) and Bcl-2–Binding Component 3 ( PUMA ) and Apoptosis that Is Caspase- Dependent and Independent of the Retinoic Acid Receptor

Anding, A. L., Chapman, J. S., Barnett, D. W., Curley, R. W., & Clagett‐Dame, M. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-0727 · Cited by 39

β-Lapachone Significantly Increases the Effect of Ionizing Radiation to Cause Mitochondrial Apoptosis via JNK Activation in Cancer Cells

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Enhanced Lysosomal Activity Is Involved in Bax Inhibitor-1-induced Regulation of the Endoplasmic Reticulum (ER) Stress Response and Cell Death against ER Stress

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