The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Mechanisms of Early Brain Injury after Subarachnoid Hemorrhage
Open accessAbstract
Apoptosis is the term given to programmed cell death, which has been widely connected to a number of intracranial pathologies including stroke, Alzheimer's disease, and more recently subarachnoid hemorrhage (SAH). Subarachnoid hemorrhage is a disease, without any form of effective treatment, that affects mainly the young and middle aged and as a result is responsible for severe disability in otherwise healthy and productive individuals. Despite intense research efforts in the field, we currently possess a very limited understanding of the underlying mechanisms that result in injury after SAH. However, a number of studies have recently indicated that apoptosis may be a major player in the pathogenesis of secondary brain injury after SAH. As a result, the apoptotic cascades present a number of potential therapeutic opportunities that may ameliorate secondary brain injury after SAH. Experimental data suggest that these cascades occur very early after the initial insult and may be related directly to physiologic sequela commonly associated with SAH. It is imperative, therefore, to obtain a thorough understanding of the early events that occur after SAH, which will enable future therapies to be developed.
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Cites
Lane, D. P. (1992) · Nature · doi:10.1038/358015a0 · Cited by 5,138
Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
Chipuk, J. E., Kuwana, T., Bouchier-Hayes, L., Droin, N. M., Newmeyer, D. D., Schuler, M., & Green, D. R. (2004) · Science · doi:10.1126/science.1092734 · Cited by 2,108 · cited 1×
“It has been suggested that the accumulation of p53 in the nucleus leads to the translocation of p53 into the cytoplasm (Sansome et al, 2001; Chipuk et al, 2004; Erster et al, 2004), where it acts either directly or indirectly on the mitochondria resulting in cytochrome c release.”
BackgroundDNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
Shieh, S.-Y., Ikeda, M., Taya, Y., & Prives, C. (1997) · Cell · doi:10.1016/s0092-8674(00)80416-x · Cited by 2,100
Apoptosis in neurodegenerative disorders
Mattson, M. P. (2000) · Nature Reviews Molecular Cell Biology · doi:10.1038/35040009 · Cited by 1,605
Cited by
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Pluta, R. M., Hansen-Schwartz, J., Dreier, J., Vajkoczy, P., Macdonald, R. L., Nishizawa, S., Kasuya, H., Wellman, G., Keller, E., Zauner, A., et al. (2009) · Neurological Research · doi:10.1179/174313209x393564 · Cited by 414
Self-citationClinical translation of nitrite therapy for cardiovascular diseases
Calvert, J. W., & Lefer, D. J. (2010) · Nitric Oxide · doi:10.1016/j.niox.2009.11.001 · Cited by 72
Self-citationVasopressin and oxytocin in CSF and plasma of patients with aneurysmal subarachnoid haemorrhage
Martin, J., Kagerbauer, S. M., Schuster, T., Blobner, M., Kochs, E. F., & Landgraf, R. (2014) · Neuropeptides · doi:10.1016/j.npep.2013.12.004 · Cited by 40
Giuliani, D., Ottani, A., Neri, L., Zaffe, D., Grieco, P., Jochem, J., Cavallini, G. M., Catania, A., & Guarini, S. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.11.004 · Cited by 38
Metadata
- Authors
- Cahill, W. J., Calvert, J. H., & Zhang, J. H.
- Venue
- Journal of Cerebral Blood Flow & Metabolism
- Publisher
- SAGE Publications
- Published
- 2006-11
- Volume
- 26
- Issue
- 11
- Pages
- 1341-1353
- ISSN
- 0271-678X (ISSN-L)
- 1559-7016
- OpenAlex
- W2023520406
- Cited by
- 630
- References
- 4
- FWCI
- 8.36
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Cahill, W. J., Calvert, J. H., & Zhang, J. H. (2006). Mechanisms of Early Brain Injury after Subarachnoid Hemorrhage. Journal of Cerebral Blood Flow & Metabolism. https://doi.org/10.1038/sj.jcbfm.9600283
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
