Exercise blood pressure response is related to left ventricular mass
Abstract
An exaggerated SBP response to exercise has been associated with increased left ventricular (LV) mass in some but not all studies. A total of 43 women and 34 men, aged 55-75 years, without evidence of cardiovascular disease, with a mean resting BP of 142+/-9/77+/-8 mmHg had their BP measured at rest and during maximal treadmill exercise. LV mass was measured using magnetic resonance imaging. LV mass was adjusted for lean body mass, which was assessed by dual energy X-ray absorptiometry. LV mass was within the normal range for the majority of the subjects. Among the resting and exercise BP indices, maximal SBP was the strongest correlate of LV mass (r=0.41, P<0.05). In multivariate analysis, maximal SBP was independently associated with LV mass after adjustment for lean body mass and gender, explaining 3% of the variance (P<0.05). Maximal exercise SBP is a modest but still independent predictor of LV mass in older persons with normal LV mass. These results raise the possibility that the SBP response to maximal exercise is an early marker of LV hypertrophy.
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Exaggerated exercise blood pressure (EEBP) recorded during clinical exercise testing is independently associated with blood pressure-related cardiovascular disease (CVD) outcomes.
“Exaggerated exercise blood pressure recorded during clinical exercise testing is independently associated with blood pressure -related cardiovascular disease outcomes”
From Cardiorespiratory Fitness, Workload, and the Blood Pressure Response to Exercise Testing (2022) · cites this paper as [12]
Several studies have shown relationships between EEBP and adverse cardiac structure and function, indicative of hypertensive heart disease.
“Several studies have also shown relationships between EEBP and adverse cardiac structure [33,34,35,36] and function [37], indicative of hypertensive heart disease.”
From The Identification and Management of High Blood Pressure Using Exercise Blood Pressure: Current Evidence and Practical Guidance (2022) · cites this paper as [34]
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- Authors
- Sung, J., Ouyang, P., Silber, H. A., Bacher, A. C., Turner, K. L., DeRegis, J. R., Hees, P. S., Shapiro, E. P., & Stewart, K. J.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- Stewart, K J
- Venue
- Journal of Human Hypertension
- Published
- 2003-05-01
- Volume
- 17
- Issue
- 5
- Pages
- 333-338
- ISSN
- 0950-9240 (ISSN-L)
- 1476-5527
- OpenAlex
- W1993764453
- Cited by
- 41
- References
- 32
- Citations by year
- 2026: 1 · 2024: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 7 · 2014: 2 · 2013: 3 · 2012: 2
- FWCI
- 0.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Human Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Heart, Lung, and Blood Institute (HL59164, R01HL059164)
- National Center for Research Resources (M01-RR02715)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Keywords
- blood pressure response to exercise, left ventricular mass, systolic blood pressure, left ventricular hypertrophy, treadmill exercise, older adults, lean body mass, hypertension, cardiovascular risk markers
- MeSH terms
- Aged, Blood Pressure, Body Composition, Diastole, Exercise Test, Female, Heart Rate, Heart Ventricles, Humans, Hypertension, Male, Middle Aged, Organ Size, Oxygen Consumption, Predictive Value of Tests, Sex Factors, Statistics as Topic, Systole, Exercise, Body Mass Index, Multivariate Analysis, Hypertrophy, Left Ventricular
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