Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue

Molecular Hydrogen in Drinking Water Protects against Neurodegenerative Changes Induced by Traumatic Brain Injury

Dohi, K., Kraemer, B. C., Erickson, M. A., McMillan, P. J., Kováč, A., Flachbartova, Z., Hansen, K. M., Shah, G. N., Sheibani, N., Salameh, T. S., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108034 · Cited by 60

Expression of the type 1 and type 2 receptors for tumor necrosis factor after traumatic spinal cord injury in adult rats

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Blast-induced moderate neurotrauma (BINT) elicits early complement activation and tumor necrosis factor alpha (TNFα) release in a rat brain

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Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis

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Neuroinflammatory Biomarkers for Traumatic Brain Injury Diagnosis and Prognosis: A TRACK-TBI Pilot Study

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Peripheral immune cells in the pathology of traumatic brain injury?

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Fibrinogen and Neuroinflammation During Traumatic Brain Injury

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Electrochemical Immunosensing of Interleukin-6 in Human Cerebrospinal Fluid and Human Serum as an Early Biomarker for Traumatic Brain Injury

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Bifunctional role of pro-inflammatory cytokines after traumatic brain injury

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Exercise attenuates neurological deficits by stimulating a critical HSP70/NF-κB/IL-6/synapsin I axis in traumatic brain injury rats

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Pharmacokinetic Alterations After Severe Head Injury

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A Novel Dehydroepiandrosterone Analog Improves Functional Recovery in a Rat Traumatic Brain Injury Model

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Pathophysiology of acute lung injury in patients with acute brain injury: the triple-hit hypothesis

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Principal components derived from CSF inflammatory profiles predict outcome in survivors after severe traumatic brain injury

Kumar, R. G., Rubin, J. E., Berger, R. P., Kochanek, P. M., & Wagner, A. K. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.12.008 · Cited by 52

Methylprednisolone Inhibits Production of Interleukin-1?? and Interleukin-6 in the Spinal Cord Following Compression Injury in Rats

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Signal Transduction Pathways Involved in Brain Death-Induced Renal Injury

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A Review and Rationale for the Use of Genetically Engineered Animals in the Study of Traumatic Brain Injury

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Effects of vitamin E against aluminum neurotoxicity in rats

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Long-Term Gliosis and Molecular Changes in the Cervical Spinal Cord of the Rhesus Monkey after Traumatic Brain Injury

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Differential Regulation of microRNAs in Patients with Ischemic Stroke

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Increased interleukin-12 levels in human cerebrospinal fluid following severe head trauma

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Systemic Neutralization of Interleukin-8 Markedly Reduces Neutrophilic Pleocytosis during Experimental Lipopolysaccharide-Induced Meningitis in Rabbits

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A Role for Tumor Necrosis Factor α in Death of Dopaminergic Neurons Following Neural Transplantation

Clarke, D. J., & Branton, R. L. (2002) · Experimental Neurology · doi:10.1006/exnr.2002.7911 · Cited by 45

The Current State of Traumatic Brain Injury Biomarker Measurement Methods

Krausz, A. D., Korley, F. K., & Burns, M. A. (2021) · Biosensors · doi:10.3390/bios11090319 · Cited by 44

Endogenous Neural Stem/Progenitor Cells Stabilize the Cortical Microenvironment after Traumatic Brain Injury

Dixon, K. J., Theus, M. H., Nelersa, C. M., Mier, J., Travieso, L. G., Yu, T., Kernie, S. G., & Liebl, D. J. (2014) · Journal of Neurotrauma · doi:10.1089/neu.2014.3390 · Cited by 44

Inflammation Following Traumatic Brain Injury in Humans: Insights from Data-Driven and Mechanistic Models into Survival and Death

Abboud, A., Mi, Q., Puccio, A. M., Okonkwo, D. O., Buliga, M., Constantine, G. M., & Yoram Vodovotz, B. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00342 · Cited by 43

Age‐dependent release of high‐mobility group box protein‐1 and cellular neuroinflammation after traumatic brain injury in mice

Webster, K. M., Sun, M., Crack, P. J., O'Brien, T. J., Shultz, S. R., & Semple, B. D. (2018) · The Journal of Comparative Neurology · doi:10.1002/cne.24589 · Cited by 44

Neuroprotective versus Neuroinflammatory Roles of Complement: From Development to Disease

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LPS antagonism of TGF‐β signaling results in prolonged survival and activation of rat primary microglia

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Role of Astrocytes in Post-traumatic Epilepsy

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Lack of correlation among intracerebral cytokines, intracranial pressure, and brain tissue oxygenation in patients with traumatic brain injury and diffuse lesions*

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FTY720 attenuates accumulation of EMAP‐II+ and MHC‐II+ monocytes in early lesions of rat traumatic brain injury

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The cutoff values of intrathecal interleukin 8 and 6 for predicting the neurological outcome in cardiac arrest victims

Oda, Y., Tsuruta, R., Kasaoka, S., Inoue, T., & Maekawa, T. (2008) · Resuscitation · doi:10.1016/j.resuscitation.2008.10.001 · Cited by 39

FTY720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation

Mencl, S., Hennig, N., Hopp, S., Schuhmann, M. K., Albert-Weißenberger, C., Sirén, A., & Kleinschnitz, C. (2014) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2014.07.010 · Cited by 38

Guilty Molecules, Guilty Minds? The Conflicting Roles of the Innate Immune Response to Traumatic Brain Injury

Hellewell, S. C., & Morganti-Kossmann, M. C. (2012) · Mediators of Inflammation · doi:10.1155/2012/356494 · Cited by 40

Aging attenuates radiation-induced expression of pro-inflammatory mediators in rat brain

Lee, W. H., Sonntag, W. E., & Lee, Y. W. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.04.009 · Cited by 38

Characterizing the relationship between systemic inflammatory response syndrome and early cardiac dysfunction in traumatic brain injury

Chaikittisilpa, N., Krishnamoorthy, V. K., Lele, A. V., Qiu, Q., & Vavilala, M. S. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.24100 · Cited by 39

α-Melanocyte-Stimulating Hormone Is Decreased in Plasma of Patients with Acute Brain Injury

Magnoni, S., Stocchetti, N., Colombo, G. I., Carlin, A., Colombo, A., Lipton, J. M., & Catania, A. P. (2003) · Journal of Neurotrauma · doi:10.1089/089771503321532833 · Cited by 35

Pathological vascular and inflammatory biomarkers of acute- and chronic-phase traumatic brain injury

Werhane, M. L., Evangelista, N. D., Clark, A. L., Sorg, S. F., Bangen, K. J., Tran, M., Schiehser, D. M., & Delano‐Wood, L. (2017) · Concussion · doi:10.2217/cnc-2016-0022 · Cited by 36

Factors influencing late presentation for breast cancer in the middle East: a systematic review.

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Induction of the Stress Response after Inflicted and Non-Inflicted Traumatic Brain Injury in Infants and Children

Lai, Y., Kochanek, P. M., Adelson, P. D., Janesko, K. L., Ruppel, R. A., & Clark, R. S. B. (2004) · Journal of Neurotrauma · doi:10.1089/089771504322972022 · Cited by 34

The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction

Chen, X., Nguyen, N., Riley, A. M., Herring, B. P., White, F. A., & Obukhov, A. G. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1407-6 · Cited by 33

Postnatal exposure to poly (I:C) impairs learning and memory through changes in synaptic plasticity gene expression in developing rat brain

Baghel, M. S., Singh, B., Dhuriya, Y. K., Shukla, R. K., Patro, N., Khanna, V. K., Patro, I. K., & Thakur, M. K. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.09.005 · Cited by 35

A Single Administration of the Peptide NAP Induces Long-Term Protective Changes Against the Consequences of Head Injury

Romano, J., Beni‐Adani, L., Levy‐Nissenbaum, O., Brenneman, D. E., Shohami, E., & Gozes, I. (2002) · Journal of Molecular Neuroscience · doi:10.1385/jmn:18:1-2:37 · Cited by 32

Genetic regulation of microglia activation, complement expression, and neurodegeneration in a rat model of traumatic brain injury

Bellander, B., Lidman, O., Ohlsson, M., Meijer, B., Piehl, F., & Svensson, M. A. (2010) · Experimental Brain Research · doi:10.1007/s00221-010-2342-z · Cited by 31

Intrathecal Etanercept Partially Restores Morphine's Antinociception in Morphine-Tolerant Rats via Attenuation of the Glutamatergic Transmission

Shen, C., Tsai, R., Tai, Y.-H., Lin, S., Chien, C., & Wong, C. (2011) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e318217f7eb · Cited by 31

Cytokines in CNS Inflammation and Disease

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Ethanol and acetaldehyde disturb TNF-alpha and IL-6 production in cultured astrocytes

Šarc, L., Wraber, B., & Lipnik‐Štangelj, M. (2010) · Human & Experimental Toxicology · doi:10.1177/0960327110388533 · Cited by 29

Cellular and molecular mechanisms of injury and spontaneous recovery

McGinn, M. J., & Povlishock, J. T. (2015) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52892-6.00005-2 · Cited by 31

Breviscapine reduces neuronal injury caused by traumatic brain injury insult: partly associated with suppression of interleukin-6 expression

Xia, Q., Jiang, L., Hu, Y., He, X., Lv, Q., & Wang, T.-H. (2017) · Neural Regeneration Research · doi:10.4103/1673-5374.198990 · Cited by 27

Granulocyte Colony-Stimulating Factor Inhibits Neutrophil Apoptosis at the Local Site after Severe Head and Thoracic Injury

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Severe Traumatic Head Injury Affects Systemic Cytokine Expression

LaPar, D. J., Rosenberger, L. H., Walters, D. M., Hedrick, T. L., Swenson, B. R., Young, J. S., Dossett, L. A., May, A. K., & Sawyer, R. G. (2012) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2011.12.015 · Cited by 26

Effect of traumatic brain injury on cognitive function in mice lacking p55 and p75 tumor necrosis factor receptors

Longhi, L. G., Ortolano, F., Zanier, E. R., Perego, C., Stocchetti, N., & Simoni, M. G. D. (2008) · Acta neurochirurgica. Supplementum · doi:10.1007/978-3-211-85578-2_80 · Cited by 26

A comparison of blood and cerebrospinal fluid cytokines (IL-1β, IL-6, IL-18, TNF-α) in neonates with perinatal hypoxia

Šumanović-Glamuzina, D., Čulo, F., Čulo, M. I., Konjevoda, P., & Raguž, M. J. (2017) · Bosnian Journal of Basic Medical Sciences · doi:10.17305/bjbms.2017.1381 · Cited by 26

Role of innate inflammation in traumatic brain injury

Bourgeois-Tardif, S., Beaumont, L. D., Rivera, J. C., Chemtob, S., & Weil, A. G. (2021) · Neurological Sciences · doi:10.1007/s10072-020-05002-3 · Cited by 24

Fibrinogen Interaction with Astrocyte ICAM-1 and PrPC Results in the Generation of ROS and Neuronal Death

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Expression of interleukin-6 messenger RNA in a rat model of diffuse axonal injury

Rhodes, J. K. J., Andrews, P., Holmes, M. C., & Seckl, J. R. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00811-x · Cited by 24

Smad3‐dependent signaling underlies the TGF‐β1‐mediated enhancement in astrocytic iNOS expression

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Experimental diffuse brain injury and a model of Alzheimer's disease exhibit disease‐specific changes in sleep and incongruous peripheral inflammation

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Altered cytokine expression and sustained hypothermia following traumatic brain injury in heat acclimated mice

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Enhancing Mesenchymal Stromal Cell Potency: Inflammatory Licensing via Mechanotransduction

Skibber, M. A., Olson, S. D., Prabhakara, K. S., Gill, B. S., & Cox, C. S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.874698 · Cited by 25

Immunity impacts cognitive deficits across neurological disorders

Shaw, B. C., Anders, V., Tinkey, R. A., Habean, M. L., Brock, O. D., Frostino, B. J., & Williams, J. L. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15999 · Cited by 27

Immune-endocrine interactions in the pathophysiology of sleep-wake disturbances following traumatic brain injury: A narrative review

Rowe, R. K., & Griesbach, G. S. (2022) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2022.04.017 · Cited by 21

Adipose tissue as a therapeutic target for vascular damage in Alzheimer's disease

Bettinetti‐Luque, M., Trujillo‐Estrada, L., García‐Fuentes, E., Andreo‐Lopez, J., Sanchez-Varo, R. M., Garrido‐Sánchez, L., Mediavilla, A. G., López, M. G., García‐Caballero, M., Gutiérrez, A., et al. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16243 · Cited by 21

Blunted IL-6 and IL-10 response to maximal aerobic exercise in patients with traumatic brain injury

Timmerman, K. L., Amonette, W. E., Markofski, M. M., Ansinelli, H. A., Gleason, E. A., Rasmussen, B. B., & Mossberg, K. A. (2014) · European Journal of Applied Physiology · doi:10.1007/s00421-014-2997-4 · Cited by 20

Immunohistochemical characterization of Fas (CD95) and Fas Ligand (FasL/CD95L) expression in the injured brain: relationship with neuronal cell death and inflammatory mediators.

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Epidemiology, Risk Factors, and Biomarkers of Post-Traumatic Epilepsy: A Comprehensive Overview

Kazis, D. A., Chatzikonstantinou, S., Ciobica, A. S., Kamal, F. Z., Burlui, V., Călin, G., & Mavroudis, I. A. (2024) · Biomedicines · doi:10.3390/biomedicines12020410 · Cited by 19

The effects of Taurine supplementation on inflammatory markers and clinical outcomes in patients with traumatic brain injury: a double-blind randomized controlled trial

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The Use of Blood-Based Biomarkers to Improve the Design of Clinical Trials of Traumatic Brain Injury

Glushakova, O. Y., Glushakov, A. V., Mannix, R., Miller, E. R., Valadka, A. B., & Hayes, R. L. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804064-5.00008-4 · Cited by 19

Tumor necrosis factor-α mediates the proliferation of rat C6 glioma cells via β-adrenergic receptors

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Fenofibrate, a peroxisome proliferator-activated receptor α-agonist, blocks lipopolysaccharide-induced inflammatory pathways in mouse liver

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Whole-brain irradiation increases NREM sleep and hypothalamic expression of IL-1β in rats

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Identification of candidate biomarkers of brain damage in a mouse model of closed head injury: a metabolomic pilot study

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Brain injury and immunosuppression

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The Role and Mechanism of Transglutaminase 2 in Regulating Hippocampal Neurogenesis after Traumatic Brain Injury

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Temporal Acute Serum Estradiol and Tumor Necrosis Factor-α Associations and Risk of Death after Severe Traumatic Brain Injury

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A Variable Height Microfluidic Device for Multiplexed Immunoassay Analysis of Traumatic Brain Injury Biomarkers

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Discrimination of cell types in mixed cortical culture using calcium imaging: A comparison to immunocytochemical labeling

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Einfluss des Schädel-Hirn-Traumas auf Zeitpunkt und Technik der Frakturversorgung

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Extracellular presence of IL-8 in the astrocyte-rich cultured cerebellar granule cells under acidosis

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Alzheimer's Disease: Fatty Acids We Eat may be Linked to a Specific Protection via Low-dose Aspirin.

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Is stroke rehabilitation a metabolic problem?

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Immunoexcitotoxicity as a Central Mechanism of Chronic Traumatic Encephalopathy – A Unifying Hypothesis

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The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes

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The Effects of Fibrinogen’s Interactions with Its Neuronal Receptors, Intercellular Adhesion Molecule-1 and Cellular Prion Protein

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Herpes Simplex Virus Type 2-Induced Mortality following Genital Infection Is Blocked by Anti-Tumor Necrosis Factor Alpha Antibody in CXCL10-Deficient Mice

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Naltrexone is neuroprotective against traumatic brain injury in mu opioid receptor knockout mice

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Assessing blood granulocyte colony-stimulating factor as a potential biomarker of acute traumatic brain injury in mice and humans

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