VNS therapy in treatment-resistant depression: clinical evidence and putative neurobiological mechanisms

Nemeroff, Charles B, Mayberg, Helen S, Krahl, Scott E, McNamara, James, Frazer, Alan, Henry, Thomas R, George, Mark S, Charney, Dennis S +1 more·2006·Neuropsychopharmacology

Cited by (495)

Items 101–200 of 495

  1. The Application of Vagus Nerve Stimulation and Deep Brain Stimulation in Depression
    Pavel Mohr, Mabel Rodríguez, Anna Slavíčková, Jan Hanka · 2011 · Neuropsychobiology
  2. Medicare patient experience with vagus nerve stimulation for treatment-resistant depression
    Feldman, Rachel L., Dunner, David L., Muller, James S., Stone, Devin A. · 2013 · Journal of Medical Economics
  3. Comparative Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation vs Citalopram for Major Depressive Disorder: A Randomized Trial
    Shaoyuan Li, Peijing Rong, Yu Wang, Guixing Jin, Xiaobing Hou, Su‐Xia Li, Xue Xiao, Wei Zhou, Yue Wu, Yaping Liu et al. · 2022 · Neuromodulation Technology at the Neural Interface
  4. EEG-desynchronization as the major mechanism of anti-epileptic action of vagal nerve stimulation in patients with intractable seizures: Clinical neurophysiological evidence
    Harinder Jaseja · 2009 · Medical Hypotheses
  5. Obesity-Associated Alterations in Glucose Metabolism Are Reversed by Chronic Bilateral Stimulation of the Abdominal Vagus Nerve
    Charles‐Henri Malbert, Chloé A. Picq, Jean‐Louis Divoux, Christine Henry, Michael Horowitz · 2017 · Diabetes
  6. Reinstatement of contextual conditioned anxiety in virtual reality and the effects of transcutaneous vagus nerve stimulation in humans
    Hannah Genheimer, Marta Andreatta, Esther Asan, Paul Pauli · 2017 · Scientific Reports
  7. Vagal stimulation for heart failure: Background and first in-man study
    Peter J. Schwartz, Gaetano Maria De Ferrari · 2009 · Heart Rhythm
  8. Vagus nerve stimulation enhances perforant path-CA3 synaptic transmission via the activation of β-adrenergic receptors and the locus coeruleus
    Huilian Shen, Yuta Fuchino, Daisuke Miyamoto, Hiroshi Nomura, Norio Matsuki · 2011 · The International Journal of Neuropsychopharmacology
  9. Electrical stimulation of the external ear acutely activates noradrenergic mechanisms in humans
    M. A. Urbin, Charles W. Lafe, Tyler W. Simpson, George Frederick Wittenberg, Bharath Chandrasekaran, Douglas J. Weber · 2021 · Brain stimulation
  10. Clinical issues in considering vagus nerve stimulation for treatment-resistant depression
    Augustus John Rush, Susan E. Siefert · 2009 · Experimental Neurology
  11. Different Transcutaneous Auricular Vagus Nerve Stimulation Parameters Modulate the Anti-Inflammatory Effects on Lipopolysaccharide-Induced Acute Inflammation in Mice
    Yoon Young Go, Won-Min Ju, Chanmi Lee, Sung-Won Chae, Jae‐Jun Song · 2022 · Biomedicines
  12. The effect of a single episode of short duration heart rate variability biofeedback on measures of anxiety and relaxation states.
    Gabriell E. Prinsloo, Wayne Elton Derman, Mike Lambert, Laurie Rauch · 2013 · International Journal of Stress Management
  13. Effects of Electroacupuncture at Auricular Concha Region on the Depressive Status of Unpredictable Chronic Mild Stress Rat Models
    Rupeng Liu, Jiliang Fang, Peijing Rong, Yufeng Zhao, Hong Meng, Hui Ben, Liang Li, Zhan-Xia Huang, Xia Li, Ying-ge Ma et al. · 2013 · Evidence-based Complementary and Alternative Medicine
  14. Heart Rate Variability as a Predictor of Negative Mood Symptoms Induced by Exercise Withdrawal
    Ali A. Weinstein, Patricia Anne Deuster, Willem J. Kop · 2007 · Medicine & Science in Sports & Exercise
  15. The heart side of brain neuromodulation
    S. Rossi, E. Santarnecchi, G. Valenza, M. Ulivelli · 2016 · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
  16. Vagal Stimulation for Heart Diseases: From Animals to Men - An Example of Translational Cardiology -
    Peter J. Schwartz · 2010 · Circulation Journal
  17. Neurostimulatory and ablative treatment options in major depressive disorder: a systematic review
    Pablo Andrade, Lieke H. M. Noblesse, Yasin Temel, Linda P.C.M. Ackermans, Lee Wei Lim, Harry W.M. Steinbusch, Veerle E. R. M. Visser-Vandewalle · 2010 · Acta Neurochirurgica
  18. Late-life Depression: Evidence-based Treatment and Promising New Directions for Research and Clinical Practice
    Carmen Andreescu, Charles F. Reynolds · 2011 · Psychiatric Clinics of North America
  19. Neuromodulation for treatment-resistant depression
    Paul E. Holtzheimer, Helen S. Mayberg · 2012 · F1000 Medicine Reports
  20. Potential Roles for Gamma-Aminobutyric Acid Signaling in Bacterial Communities
    Sarah J. Quillin, Peter Tran, Arthur B. Prindle · 2021 · Bioelectricity
  21. Transcutaneous Vagus Nerve Stimulation Modulates EEG Microstates and Delta Activity in Healthy Subjects
    Lorenzo Ricci, Pierpaolo Croce, Jacopo Lanzone, Marilisa Boscarino, Filippo Zappasodi, Mario Tombini, Vincenzo Di Lazzaro, Giovanni Assenza · 2020 · Brain Sciences
  22. The Story of Ferumoxytol: Synthesis Production, Current Clinical Applications, and Therapeutic Potential
    Mengmeng Long, Yan Li, Hongliang He, Ning Gu · 2023 · Advanced Healthcare Materials
  23. Of Sophists and Spin-Doctors: Industry-Sponsored Ghostwriting and the Crisis of Academic Medicine
    Leemon McHenry · 2010 · Mens Sana monographs
  24. Neuromodulation - Science and Practice in Epilepsy: Vagus Nerve Stimulation, Thalamic Deep Brain Stimulation, and Responsive NeuroStimulation
    Matthew S. Markert, Robert S. Fisher · 2018 · Expert Review of Neurotherapeutics
  25. The Role of Conflict of Interest in Reporting of Scientific Information
    Richard S. Irwin · 2009 · CHEST Journal
  26. Vagus nerve stimulation ameliorated deficits in one-way active avoidance learning and stimulated hippocampal neurogenesis in bulbectomized rats
    Nils Gebhardt, Karl‐Jürgen Bär, Michael Karl Boettger, Gisela Grecksch, Gerburg Keilhoff, Rupert Reichart, Axel Becker · 2012 · Brain stimulation
  27. Stress-induced vagal activity influences anxiety-relevant prefrontal and amygdala neuronal oscillations in male mice
    Toya Okonogi, Nahoko Kuga, Musashi Yamakawa, Tasuku Kayama, Yuji Ikegaya, Takuya Sasaki · 2024 · Nature Communications
  28. Endocrine and immune effects of non-convulsive neurostimulation in depression: A systematic review
    Andrew J. Perrin, Carmine Maria Pariante · 2020 · Brain Behavior and Immunity
  29. The vagus nerve is necessary for the rapid and widespread neuronal activation in the brain following oral administration of psychoactive bacteria
    Aadil Bharwani, Christine L. West, Kevin P. Champagne-Jorgensen, Karen‐Anne McVey Neufeld, Joseph Ruberto, Wolfgang Kunze, John Bienenstock, Paul Forsythe · 2019 · Neuropharmacology
  30. Neurobiology of estrogen status in deep craniofacial pain
    David A. Bereiter, Keiichiro Okamoto · 2011 · International review of neurobiology
  31. Effect of a 12-Week Yoga Therapy Program on Mental Health Status in Elderly Women Inmates of a Hospice
    Bhavanani, AnandaBalayogi, Ramanathan, Meena, Trakroo, Madanmohan · 2017 · International Journal of Yoga
  32. Transcutaneous vagus nerve stimulation (tVNS) modulates flow experience
    Lorenza S. Colzato, Gina Wolters, Corinna Peifer · 2017 · Experimental Brain Research
  33. Electroencephalographic correlates of low-frequency vagus nerve stimulation therapy for Crohn’s disease
    Astrid Kibleur, Sonia Pellissier A, Valérie Sinniger, J Robert, Eloïse Gronlier, Didier Clarençon, Laurent Vercueil, D. Hoffmann, Bruno L. Bonaz, Olivier David A · 2018 · Clinical Neurophysiology
  34. Transcutaneous vagus nerve stimulation and extinction of prepared fear: A conceptual non-replication
    A. Burger, I. Van Diest, W. van der Does, M. Hysaj, J. Thayer, J. Brosschot, B. Verkuil · 2018 · Scientific Reports
  35. A zebrafish-centric approach to antiepileptic drug development
    Scott C. Baraban · 2021 · Disease Models & Mechanisms
  36. Tractography of the Brainstem in Major Depressive Disorder Using Diffusion Tensor Imaging
    Yun Ju Christine Song, Mayuresh S. Korgaonkar, Lucy V. Armstrong, Sarah Eagles, Leanne Maree Williams, Stuart M. Grieve · 2014 · PLoS ONE
  37. Common Genes Contribute to Depressive Symptoms and Heart Rate Variability: The Twins Heart Study
    Shaoyong Su, Rachel J. Lampert, Forrester A. Lee, J. Douglas Bremner, Harold Snieder, Linda Ramball Jones, Nancy V. Murrah, Jack H. Goldberg, Viola Vaccarino · 2010 · Twin Research and Human Genetics
  38. Vagus Nerve Stimulation, Depression, and Inflammation
    Undurti Narasimha Das · 2007 · Neuropsychopharmacology
  39. Evolving refractory major depressive disorder diagnostic and treatment paradigms: toward closed-loop therapeutics
    Matthew Peter Ward · 2010 · Frontiers in Neuroengineering
  40. Acute Vagal Nerve Stimulation Lowers α2 Adrenoceptor Availability: Possible Mechanism of Therapeutic Action
    Anne Marlene Landau, Suzan Dyve, Steen Jakobsen, Aage Kristian Olsen Alstrup, ALBERT H. GJEDDE, Doris J. Doudet · 2015 · Brain stimulation
  41. Neurostimulation therapies for treatment resistant depression: A focus on vagus nerve stimulation and deep brain stimulation
    Rizvi, Sakina J., Donovan, Madelin, Giacobbe, Peter, Placenza, Franca, Rotzinger, Susan, Kennedy, Sidney H. · 2011 · International Review of Psychiatry
  42. Nerve growth factor (NGF) has novel antidepressant-like properties in rats
    Overstreet, David H., Fredericks, Kellie, Knapp, Darin, Breese, George, McMichael, John · 2010 · Pharmacology Biochemistry and Behavior
  43. Biological basis for the surgical treatment of depression
    Aviva Abosch, Garth Rees Cosgrove · 2008 · Neurosurgical FOCUS
  44. Tonic and phasic transcutaneous auricular vagus nerve stimulation (taVNS) both evoke rapid and transient pupil dilation
    Lina I. Skora, Anna Marzecová, Gerhard Jocham · 2024 · Brain stimulation
  45. Value of Functionalized Superparamagnetic Iron Oxide Nanoparticles in the Diagnosis and Treatment of Acute Temporal Lobe Epilepsy on MRI
    Tingting Fu, Qingxia Kong, Huaqiang Sheng, Lingyun Gao · 2016 · Neural Plasticity
  46. Multi-session transcutaneous auricular vagus nerve stimulation for Parkinson's disease: evaluating feasibility, safety, and preliminary efficacy
    Daniel H. Lench, Travis H. Turner, Colin McLeod, Heather A. Boger, Lilia Lovera, Lisa Heidelberg, Jordan Elm, Anh Ngoc Bao Phan, Bashar W. Badran, Vanessa K. Hinson · 2023 · Frontiers in Neurology
  47. Transcutaneous Auricular Vagus Nerve Stimulation Promotes White Matter Repair and Improves Dysphagia Symptoms in Cerebral Ischemia Model Rats
    Lu Long, Qianwen Zang, Gongwei Jia, Meng Fan, Liping Zhang, Yingqiang Qi, Yilin Liu, Lehua Yu, Sanrong Wang · 2022 · Frontiers in Behavioral Neuroscience
  48. Multi-species probiotic supplement enhances vagal nerve function – results of a randomized controlled trial in patients with depression and healthy controls
    Sabrina Mörkl, Martin Narrath, Daria Schlotmann, Marie-Therese Sallmutter, J Putz, Julia Lang, Andreas Brandstätter, René Pilz, Helmut Karl Lackner, Nandu Goswami et al. · 2025 · Gut Microbes
  49. Investigation of mechanisms of vagus nerve stimulation for seizure using finite element modeling
    Jeffrey E. Arle, Kristen W. Carlson, Longzhi Mei · 2016 · Epilepsy Research
  50. Vagal nerve stimulation modifies neuronal activity and the proteome of excitatory synapses of amygdala/piriform cortex
    Georgia M. Alexander, Yang Zhong Huang, Erik J. Soderblom, Xiao‐Ping He, Martin Arthur Moseley, James O McNamara · 2016 · Journal of Neurochemistry
  51. Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS): Technique, Targeting, and Considerations
    Bashar W. Badran, Alfred B. Yu, Devin Adair, Georgia M. Mappin, William H. DeVries, Dorothea Jenkins, Mark S. George, Marom Bikson · 2019 · Journal of Visualized Experiments
  52. Health care for the whole person: Research update.
    Nadine J. Kaslow, Annie M. Bollini, Benjamin G. Druss, Robert L. Glueckauf, Lewis R. Goldfrank, Kelly J. Kelleher, Annette Marie La Greca, R. Enrique Varela, Samuel S.‐H. Wang, Linda Weinreb et al. · 2007 · Professional Psychology Research and Practice
  53. Direct and Transcutaneous Vagus Nerve Stimulation for Treatment of Tinnitus: A Scoping Review
    Natalia Yakunina, Eui‐Cheol Nam · 2021 · Frontiers in Neuroscience
  54. Effect of an eight-week smartphone-guided HRV-biofeedback intervention on autonomic function and impulsivity in healthy controls
    Andy Schumann, Stefanie Köhler, Lisa Brotte, Karl‐Jürgen Bär · 2019 · Physiological Measurement
  55. The effects of transcutaneous auricular vagal nerve stimulation on pupil size
    Fioravante Capone, Francesco Motolese, Antonio Di Zazzo, Marco Antonini, Alessandro Magliozzi, Mariagrazia Rossi, Massimo Marano, Fabio Pilato, Gabriella Musumeci, Marco Coassin et al. · 2021 · Clinical Neurophysiology
  56. Sub-chronic dietary tryptophan depletion – An animal model of depression with improved face and good construct validity
    M. Franklin, Isabel Bermúdez, Harald Murck, Nicolas Singewald, Stefano Gaburro · 2011 · Journal of Psychiatric Research
  57. Genetic, Molecular and Clinical Determinants for the Involvement of Aldosterone and Its Receptors in Major Depression
    Harald Murck, Matthias Büttner, Tilo T. J. Kircher, Carsten Konrad · 2014 · Nephron Physiology
  58. Auricular Transcutaneous Vagus Nerve Stimulation Specifically Enhances Working Memory Gate Closing Mechanism: A System Neurophysiological Study
    Anyla Konjusha, Shijing Yu, Moritz Mückschel, Lorenza S. Colzato, Tjalf Ziemssen, Christian Beste · 2023 · Journal of Neuroscience
  59. Vagus Nerve Stimulation Alters Phase Synchrony of the Anterior Cingulate Cortex and Facilitates Decision Making in Rats
    Bing Cao, Jun Wang, Mahadi H. Shahed, Beth Jelfs, Rosa H. M. Chan, Ying Li · 2016 · Scientific Reports
  60. The Cholinergic Anti-Inflammatory Pathway as a Conceptual Framework to Treat Inflammation-Mediated Renal Injury
    J. Jarczyk, B. Yard, S. Hoeger · 2019 · Kidney & Blood Pressure Research
  61. Transcutaneous vagus nerve stimulation modulates attentional resource deployment towards social cues
    María J. Maraver, Laura Steenbergen, Romina Hossein, Rossana Actis-Grosso, Paola Ricciardelli, Bernhard Hommel, Lorenza S. Colzato · 2020 · Neuropsychologia
  62. Autonomic Modulation by Electrical Stimulation of the Parasympathetic Nervous System: An Emerging Intervention for Cardiovascular Diseases
    Bo He, Zhibing Lu, Wenbo He, Bing S Huang, Hong Jiang · 2016 · Cardiovascular Therapeutics
  63. Therapeutic Modalities for Treatment Resistant Depression: Focus on Vagal Nerve Stimulation and Ketamine
    Aparna P. Shah, Flavia Regina Carreno, Alan Frazer · 2014 · Clinical Psychopharmacology and Neuroscience
  64. Vagus nerve stimulation as a strategy to prevent and manage metabolic syndrome
    Undurti Narasimha Das · 2010 · Medical Hypotheses
  65. Can vagus nerve stimulation halt or ameliorate rheumatoid arthritis and lupus?
    Undurti Narasimha Das · 2011 · Lipids in Health and Disease
  66. The brain-gut axis dysfunctions and hypersensitivity to food antigens in the etiopathogenesis of schizophrenia
    Hanna Karakuła‐Juchnowicz, Michał Dzikowski, Agnieszka Pelczarska-Jamroga, Izabela Dzikowska, Dariusz Juchnowicz · 2015 · Psychiatria Polska
  67. The Effects of Noninvasive Vagus Nerve Stimulation on Fatigue in Participants With Primary Sjögren’s Syndrome
    Jessica R. Tarn, Evelyn Evans, Emmanuella Young Traianos, Alexis Collins, Mryto Stylianou, Jehill D. Parikh, Yang Bai, Guan Yu, James Frith, Dennis William Lendrem et al. · 2022 · Neuromodulation Technology at the Neural Interface
  68. Modulation of Muscle Tone and Sympathovagal Balance in Cervical Dystonia Using Percutaneous Stimulation of the Auricular Vagus Nerve
    Stefan Kampusch, Eugenijus Kaniušas, József Constantin Széles · 2015 · Artificial Organs
  69. Conflicts of interest of editors of medical journals
    Waqas Zia Haque, Abu Minhajuddin, Arjun Gupta, Deepak Agrawal · 2018 · PLoS ONE
  70. Long-term results of vagus nerve stimulation in children and adolescents with drug-resistant epilepsy
    Beata Majkowska-Zwolińska, Piotr Zwoliński, Marcin Roszkowski, Krzysztof Drabik · 2012 · Child s Nervous System
  71. Seizure prophylaxis in an animal model of epilepsy by dietary fluoxetine supplementation
    Alyssa Richman, Stephen C. Heinrichs · 2007 · Epilepsy Research
  72. Signal processing in the vagus nerve: Hypotheses based on new genetic and anatomical evidence
    Clare Shaffer, Lisa Feldman Barrett, Karen S. Quigley · 2023 · Biological Psychology
  73. Transcutaneous Auricular Vagus Nerve Stimulation Combined With Slow Breathing: Speculations on Potential Applications and Technical Considerations
    Mikołaj Tytus Szulczewski · 2021 · Neuromodulation Technology at the Neural Interface
  74. The vagal nerve stimulation outcome, and laryngeal effect: Otolaryngologists roles and perspective
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  75. Orally Ingested Self‐Powered Stimulators for Targeted Gut–Brain Axis Electrostimulation to Treat Obesity and Metabolic Disorders
    Cam‐Hoa Mac, Hsien‐Meng Tai, Sheng‐Min Huang, Hsu‐Hsia Peng, Amit Kumar Sharma, Giang Le Thi Nguyen, Pei‐Ju Chang, Jui‐To Wang, Yen Chang, Yu‐Jung Lin et al. · 2024 · Advanced Materials
  76. Chronic vagal stimulation in patients with congestive heart failure
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  77. Emerging treatments for depression
    Paul E. Holtzheimer, Charles B. Nemeroff · 2006 · Expert Opinion on Pharmacotherapy
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  80. Respiratory-gated auricular vagal afferent nerve stimulation (RAVANS) modulates brain response to stress in major depression
    Ronald Gerardo Garcia, Justine E. Cohen, Arielle D. Stanford, Aileen S. Gabriel, Jessica A. Stowell, Harlyn G. Aizley, Riccardo Barbieri, David Gitlin, Vitaly Napadow, Jill M. Goldstein · 2021 · Journal of Psychiatric Research
  81. A soft, scalable and adaptable multi-contact cuff electrode for targeted peripheral nerve modulation
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  82. Activation of signaling pathways downstream of the brain-derived neurotrophic factor receptor, TrkB, in the rat brain by vagal nerve stimulation and antidepressant drugs
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  83. Vagus nerve stimulation: A proven therapy for treatment of epilepsy strives to improve efficacy and expand applications
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  84. Transcutaneous Auricular Vagus Nerve Stimulation Improves Inflammation but Does Not Interfere with Cardiac Modulation and Clinical Symptoms of Individuals with COVID-19: A Randomized Clinical Trial
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  88. Vagus nerve stimulation therapy in treatment‐resistant depression: A series report
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  91. Electrocorticography Analysis in Patients With Dual Neurostimulators Supports Desynchronization as a Mechanism of Action for Acute Vagal Nerve Stimulator Stimulation
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  93. Vagus nerve stimulation for depression: rationale, anatomical and physiological basis of efficacy and future prospects
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  97. Major Depressive Disorder
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  98. Organotopic organization of the porcine mid-cervical vagus nerve
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  99. Cranial Nerves IX, X, XI, and XII
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  100. Vagus nerve stimulation: Can it be used in adolescents or children with treatment-resistant depression?
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