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A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

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Identification of the breast cancer susceptibility gene BRCA2

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Risks of cancer in BRCA1-mutation carriers

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Gatekeepers and caretakers

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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.

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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

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BRCA2 Is Required for Homology-Directed Repair of Chromosomal Breaks

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The Fanconi anemia DNA maintenance pathway: focus on the FANCE and FANCF proteins

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Radiation-induced epigenome deregulation in the male germline

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p53 and DNA damage checkpoint responses in the human prostate

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MOLECULAR STRESS SIGNALING IN BREAST EPITHELIAL CELLS Characterization of the Regulation of the Breast Cancer Susceptibility Gene 1 (BRCA1) by Stress Signaling and Design of an Epidemiological Study Examining the Effect of Glucocorticoid Receptor Genetic Variants on Breast Cancer Risk

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Analysis and characterization of chemo- and radiation therapy sensitizing strategies in tumours with focus on effects of phenothiazines on DNA damage response signalling

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Radiation-induced deregulation of PiRNA pathway proteins : a possible molecular mechanism underlying transgenerational epigenomic instability

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Functional analysis of the Rad51d (E233G) breast cancer associated polymorphism and a pharmacogenetic evaluation of RAD51D status

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DNA Repair Mechanisms in Breast Cancer Stem Cells

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FANCD1/BRCA2 and FANCD2

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DNA damage response activated by anti-cancer agent, irofulven

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Hereditary Issues In Ovarian Cancer

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Neuronal DNA Double Strand Break Damage and Repair Following Sublethal iGluR Activation, and the Neuroprotective Effects of Melatonin

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Screening Women With Known or Suspected Cancer Gene Mutations

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DNA Repair, Overview

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Universidade Federal do Rio Grande do Sul Programa de Pós Graduação em Genética e Biologia Molecular

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Commentary EMSY links breast cancer gene 2 to the ‘Royal Family’

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New functions for the major vault protein in the ionizing radiation induced stress response and DNA repair

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RADIATION RESPONSES OF CHEMORESISTANT ADENOCARCINOMA CELLS: FROM MOLECULAR MECHANISMS TO NEW REVERSAL STRATEGIES

Luzhna, L. (2009) · Open ULeth Scholarship (OPUS) (University of Lethbridge)

Hormonal activation of genes through nongenomic pathways by estrogen and structurally diverse estrogenic compounds

Li, X. (2006) · OakTrust (Texas A&M University Libraries)

Identification of cancer relevant synthetic genetic interactions with cohesin mutations in Saccharomyces cerevisiae

Reytan, S. (2017) · cIRcle (University of British Columbia) · doi:10.14288/1.0347987

Hypoxia Suppresses DNA Repair: Implications for Cancer Progression and Treatment

Chan, N. H. L. (2011) · TSpace (University of Toronto)

Uso do silenciamento gênico mediado por RNA de interferência e de TAL effector nucleases para aumento de eventos gene targeting em células de cão

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Functional DNA repair assays with clinical and translational applications

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Hereditary Breast Cancer in Selected Populations: Screening RECQL Gene in Ontario, Canada, and Exploring BRCA1/2 and PALB2 in the Caribbean

Ahmed, H. (2018) · TSpace (University of Toronto)

Fundamental and clinical knowledge about breast cancer predisposition syndromes

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Design of BRC analogous peptides based on the complex BRC8–RAD51 and the preliminary study on the peptide structures

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Evaluation of breast screening strategies in a high risk breast and ovarian cancer clinic

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The latest first-line treatment options for ovarian cancer: focus on maintenance therapy

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The combination strategy with epigenetic therapy, chemotherapy, and immunotherapy

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Defining the Role of the Histone 3.3 (H3.3G34R) Mutation in the Pathogenesis of Pediatric High Grade Astrocytoma

Kim, B. (2020) · TSpace (University of Toronto)

Hybrid Bioactive Nanoparticles for Modulation of Tumor Microenvironment and Enhancing Radiation and Chemotherapy Efficacy

Amini, M. A. (2019) · TSpace (University of Toronto)

Epigenetic Signatures of Breast Cancer Genes

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Papillomavirus Replication

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DNA Repair, Overview

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Olaparib maintenance therapy after frontline chemotherapy in patients with BRCA-mutated ovarian cancer: real-world results in expanded access program

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Epigenetic therapy and DNA damage response

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A novel RBBP8 (c.841G>T) germline mutation is a predisposition mutation in familial hereditary cancer syndromePreprint

Yan, J., Wu, J., Wang, Y., Di, X., Jiang, H., Wen, D., & Zhang, S. (2023) · Research Square · doi:10.21203/rs.3.rs-2523392/v1

Self-Care: Seeking Queer Liberation from the Medical Gaze and Genetic Fatalism

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Facing the conundrum: which first-line therapy should be used for patients with metastatic triple-negative breast cancer carrying germline BRCA mutation?

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Esophageal squamous cell carcinoma in a patient with BRCA1 mutation: a rare association

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Ionizing Radiation as a Carcinogen

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Patient perspective: Is intensive screening of women at high risk of breast cancer evidence-based medicine or déjà vu ?

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Exploring the Ligandability of 53BP1 through Fragment-Based Approaches

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All roads lead to mitosis: A common requirement for DNA replication stress-dependent and -independent killing of BRCA-deficient cells

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Introduction to breast cancer and genetic testing

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Homologous Recombination Is Associated with Enhanced Anti-Tumor Innate Immunity and Favorable Prognosis in Head and Neck Cancer

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Analysis of telomere maintenance in artemis defective human cell lines

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Cap a un model complet de la xarxa molecular alterada en l’anèmia de Fanconi i el càncer de mama

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Additional file 1 of Functional pre-therapeutic evaluation by genome editing of variants of uncertain significance of essential tumor suppressor genes

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Optimisation de l’angiomammographie et de l’angiotomosynthèse double-énergie

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Investigating cancer aetiology through the analysis of somatic mutation signatures

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Stabilité du génome et rôle des INGs dans la réponse aux dommages de l'ADN

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Impact of microbiota on intestinal stem cells survival after irradiation

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Détection de l'ADN circulant chez le sujet sain et le patient atteint d'un cancer métastatique par PCR digitale en gouttelettes

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Residential Radon Levels and Ovarian Cancer Among Postmenopausal Women

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Functional assays for BRCA1 and BRCA2 variant analysis: new tools and their applications

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SIK2 drives cisplatin chemoresistance in BRAF-wild-type anaplastic thyroid cacner by phosphorylating AURKB to activate RAD51- dependent homologous recombinationPreprint

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Comparative analyses of prolonged stress responses of breast carcinoma cells after hypofractionated irradiation in vitro and in vivoPreprint

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Multi-database analysis of BRCA1 and GATA3 reveals distinct molecular features and prognostic significance in breast cancer

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Insights into MYC biology through investigation of synthetic lethal interactions with MYC deregulation

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MOLECULAR MECHANISMS OF RADIATION-INDUCED BYSTANDER EFFECTS IN VIVO

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Emerging Therapeutic Targets for Pancreatic Cancer

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Investigation of telomere maintenance in BRCA2 defective mammalian cell lines

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The Role of DNA Damage and Repair in Ganciclovir-mediated Cytotoxicity.

O’Konek, J. J. (2008) · Deep Blue (University of Michigan)

Therapeutic Exploitation of Tumor Cell Defects in Homologous Recombination

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Abstract SY28-02: Connections in the BRCA1-BRCA2 pathway of homologous recombination: Implications for breast cancer development and treatment

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Breast cancer cells with deficiencies in BRCA1/BRCA2 show hypersensitivity to mitomycin C

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Progress of BRCA1 in radiation induced breast carcinoma

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Homologous repair of DNA damage and tumorigenesis:the BRCA connection

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