HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination

Cellular Motility Driven by Assembly and Disassembly of Actin Filaments

Pollard, T. D., & Borisy, G. G. (2003) · Cell · doi:10.1016/s0092-8674(03)00120-x · Cited by 4,334

HDAC6 is a microtubule-associated deacetylase

Hubbert, C., Guardiola, A., Shao, R., Kawaguchi, Y., Ito, A., Nixon, A., Yoshida, M., Wang, X.-F., & Yao, T.-P. (2002) · Nature · doi:10.1038/417455a · Cited by 2,403

Acetylation of Histones and Transcription-Related Factors

Sterner, D. E., & Berger, S. L. (2000) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.64.2.435-459.2000 · Cited by 1,824

Acetylation and deacetylation of non-histone proteins

Glozak, M. A., Sengupta, N., Zhang, X., & Seto, E. (2005) · Gene · doi:10.1016/j.gene.2005.09.010 · Cited by 1,584

The Human Sir2 Ortholog, SIRT2, Is an NAD+-Dependent Tubulin Deacetylase

North, B. J., Marshall, B. L., Borra, M. T., Denu, J. M., & Verdin, E. M. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00038-8 · Cited by 1,542

The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress

Kawaguchi, Y., Kovacs, J. J., McLaurin, A. C., Vance, J. M., Ito, A., & Yao, T. (2003) · Cell · doi:10.1016/s0092-8674(03)00939-5 · Cited by 1,529

Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery

Pratt, W. B., & Toft, D. O. (2003) · Experimental Biology and Medicine · doi:10.1177/153537020322800201 · Cited by 1,497

Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey

Kim, S. C., Sprung, R., Chen, Y., Xu, Y., Ball, H., Pei, J., Cheng, T., Kho, Y., Xiao, H., Xiao, L., et al. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.06.026 · Cited by 1,487

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

Watts, G. D. J., Wymer, J., Kovach, M. J., Mehta, S. G., Mumm, S., Darvish, D., Pestronk, A., Whyte, M. P., & Kimonis, V. E. (2004) · Nature Genetics · doi:10.1038/ng1332 · Cited by 1,391

Acetylation: a regulatory modification to rival phosphorylation?

Kouzarides, T. (2000) · The EMBO Journal · doi:10.1093/emboj/19.6.1176 · Cited by 1,155

HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

Kovacs, J. J., Murphy, P. J. M., Gaillard, S., Zhao, X., Wu, J.-T., Nicchitta, C. V., Yoshida, M., Toft, D. O., Pratt, W. B., & Yao, T.-P. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.04.021 · Cited by 1,153

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

Haggarty, S. J., Koeller, K. M., Wong, J. C., Grozinger, C. M., & Schreiber, S. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0430973100 · Cited by 1,066

Microtubule Acetylation Promotes Kinesin-1 Binding and Transport

Reed, N. A., Cai, D., Blasius, T. L., Jih, G. T., Meyhofer, E., Gaertig, J., & Verhey, K. J. (2006) · Current Biology · doi:10.1016/j.cub.2006.09.014 · Cited by 919

Navigating the Chaperone Network: An Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone

Zhao, R., Davey, M., Hsu, Y.-C., Kaplanek, P., Tong, A., Parsons, A. B., Krogan, N., Cagney, G., Mai, D., Greenblatt, J., et al. (2005) · Cell · doi:10.1016/j.cell.2004.12.024 · Cited by 819

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

Hallows, W. C., Lee, S., & Denu, J. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604392103 · Cited by 792

Three proteins define a class of human histone deacetylases related to yeast Hda1p

Grozinger, C. M., Hassig, C. A., & Schreiber, S. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.9.4868 · Cited by 770

Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90

Bali, P., Pranpat, M., Bradner, J., Balasis, M., Fiskus, W., Guo, F., Rocha, K., Kumaraswamy, S., Boyapalle, S., Atadja, P., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.c500186200 · Cited by 755

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

Gao, L., Cueto, M. A., Asselbergs, F., & Atadja, P. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111871200 · Cited by 744

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

Zhang, Y., Li, N., Caron, C., Matthias, G., Hess, D., Khochbin, S., & Matthias, P. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg115 · Cited by 740 · cited 7×

Untitled work

(2002) · PubMed · Cited by 732

In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation

Matsuyama, A., Shimazu, T., Sumida, Y., Saito, A., Yoshimatsu, Y., Seigneurin‐Berny, D., Osada, H., Komatsu, Y., Nishino, N., Khochbin, S., et al. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf682 · Cited by 720

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin.

Iwata, A., Riley, B. E., Johnston, J. A., & Kopito, R. R. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508786200 · Cited by 719

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

Schwer, B., Bunkenborg, J., Verdin, R. O., Andersen, J. S., & Verdin, E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603968103 · Cited by 705

Mechanism of Actin-Based Motility

Pantaloni, D., Clainche, C. L., & Carlier, M. (2001) · Science · doi:10.1126/science.1059975 · Cited by 701

Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma

Hideshima, T., Bradner, J. E., Wong, J. Y. Y., Chauhan, D., Richardson, P. G. G., Schreiber, S. L., & Anderson, K. C. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503221102 · Cited by 603

Acetylation of the C Terminus of Ku70 by CBP and PCAF Controls Bax-Mediated Apoptosis

Cohen, H. Y., Lavu, S., Bitterman, K. J., Hekking, B., Imahiyerobo, T. A., Miller, C. M., Frye, R. A., Ploegh, H. L., Kessler, B. M., & Sinclair, D. A. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00094-2 · Cited by 594

Histone Deacetylase Is a Target of Valproic Acid-Mediated Cellular Differentiation

Gurvich, N., Tsygankova, O. M., Meinkoth, J. L., & Klein, P. S. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-0799 · Cited by 470

p300 Transcriptional Repression Is Mediated by SUMO Modification

Girdwood, D., Bumpass, D. C., Vaughan, O. A., Thain, A., Anderson, L. A., Snowden, A. W., Garcia-Wilson, E., Perkins, N. D., & Hay, R. T. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00141-2 · Cited by 448

Class II Histone Deacetylases: from Sequence to Function, Regulation, and Clinical Implication

Yang, X., & Grégoire, S. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.8.2873-2884.2005 · Cited by 428

An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Scroggins, B. T., Robzyk, K., Wang, D., Marcu, M. G., Tsutsumi, S., Beebe, K., Cotter, R. J., Felts, S., Toft, D., Karnitz, L., et al. (2007) · Molecular Cell · doi:10.1016/j.molcel.2006.12.008 · Cited by 413

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors

Bradbury, C. A., Khanim, F. L., Hayden, R., Bunce, C. M., White, D. A., Drayson, M. T., Craddock, C., & Turner, B. M. (2005) · Leukemia · doi:10.1038/sj.leu.2403910 · Cited by 410

Lysine acetylation and the bromodomain: a new partnership for signaling

Yang, X. (2004) · BioEssays · doi:10.1002/bies.20104 · Cited by 371

ENDOPLASMIC RETICULUM–ASSOCIATED DEGRADATION

Römisch, K. (2005) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.012704.133250 · Cited by 370

The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides

Goldberg, A. L., Cascio, P., Šarić, T., & Rock, K. L. (2002) · Molecular Immunology · doi:10.1016/s0161-5890(02)00098-6 · Cited by 342

ETO, a Target of t(8;21) in Acute Leukemia, Makes Distinct Contacts with Multiple Histone Deacetylases and Binds mSin3A through Its Oligomerization Domain

Amann, J. M., Nip, J., Strom, D. K., Lutterbach, B. A., Harada, H., Lenny, N. T., Downing, J. R., Meyers, S., & Hiebert, S. W. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.19.6470-6483.2001 · Cited by 336

Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

Seigneurin-Berny, D., Verdel, A., Curtet, S., Lemercier, C., Garin, J., Rousseaux, S., & Khochbin, S. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.23.8035-8044.2001 · Cited by 335

Runx2 (Cbfa1, AML-3) Interacts with Histone Deacetylase 6 and Represses the p21 CIP1/WAF1 Promoter

Westendorf, J. J., Zaidi, S. K., Cascino, J. E., Kahler, R. A., van Wijnen, A. J., Lian, J. B., Yoshida, M., Stein, G. S., & Li, X. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.22.7982-7992.2002 · Cited by 319

Differential roles for the coactivators CBP and p300 on TCF/β-catenin-mediated survivin gene expression

Ma, H., Nguyen, C., Lee, K., & Kahn, M. (2005) · Oncogene · doi:10.1038/sj.onc.1208433 · Cited by 308

Class II Histone Deacetylases Are Associated with VHL-Independent Regulation of Hypoxia-Inducible Factor 1α

Qian, D. Z., Kachhap, S. K., Collis, S. J., Verheul, H. M. W., Carducci, M. A., Atadja, P. W., & Пили, Р. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-4598 · Cited by 308

HDAC6 Expression Is Correlated with Better Survival in Breast Cancer

Zhang, Z., Yamashita, H., Toyama, T., Sugiura, H., Omoto, Y., Ando, Y., Mita, K., Hamaguchi, M., Hayashi, S., & Iwase, H. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-0455 · Cited by 295

Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability

Caron, C., Boyault, C., & Khochbin, S. (2005) · BioEssays · doi:10.1002/bies.20210 · Cited by 292

HDAC6–p97/VCP controlled polyubiquitin chain turnover

Boyault, C., Gilquin, B., Zhang, Y., Rybin, V., Garman, E. F., Meyer‐Klaucke, W., Matthias, P., Müller, C. W., & Khochbin, S. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601210 · Cited by 280

Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer

Saji, S., Kawakami, M., Hayashi, S., Yoshida, N., Hirose, M., Horiguchi, S.-I., Ito, A., Funata, N., Schreiber, S. L., Yoshida, M., et al. (2005) · Oncogene · doi:10.1038/sj.onc.1208646 · Cited by 266

Histone Deacetylase Inhibitors Induce VHL and Ubiquitin-Independent Proteasomal Degradation of Hypoxia-Inducible Factor 1α

Kong, X., Lin, Z., Liang, D., Fath, D., Sang, N., & Caro, J. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.6.2019-2028.2006 · Cited by 258

Molecular Cloning and Characterization of a Novel Histone Deacetylase HDAC10

Guardiola, A. R., & Yao, T.-P. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109861200 · Cited by 253

Ligand-Dependent Nuclear Receptor Corepressor LCoR Functions by Histone Deacetylase-Dependent and -Independent Mechanisms

Fernandes, I., Bastien, Y., Wai, T., Nygard, K. L., Lin, R., Cormier, O., Lee, H. S., Eng, F., Bertos, N., Pelletier, N., et al. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00014-5 · Cited by 252

A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts

Destaing, O., Saltel, F., Gilquin, B., Chabadel, A., Khochbin, S., Ory, S., & Jurdic, P. (2005) · Journal of Cell Science · doi:10.1242/jcs.02425 · Cited by 244

Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs

Blagosklonny, M. V. (2002) · Leukemia · doi:10.1038/sj.leu.2402415 · Cited by 237

Functional Division of Substrate Processing Cofactors of the Ubiquitin-Selective Cdc48 Chaperone

Rumpf, S., & Jentsch, S. (2006) · Molecular Cell · doi:10.1016/j.molcel.2005.12.014 · Cited by 236

Assembly and mechanosensory function of focal adhesions: experiments and models

Bershadsky, A. D., Ballestrem, C., Carramusa, L., Zilberman, Y., Gilquin, B., Khochbin, S., Alexandrova, A. Y., Verkhovsky, A. B., Shemesh, T., & Kozlov, M. M. (2005) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2005.11.001 · Cited by 229

Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes

Hook, S. S., Orian, A., Cowley, S. M., & Eisenman, R. N. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172511699 · Cited by 229

Identification of a New Family of Higher Eukaryotic Histone Deacetylases

Verdel, A., & Khochbin, S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.4.2440 · Cited by 227

Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm

Verdel, A., Curtet, S., Brocard, M.-P., Rousseaux, S., Lemercier, C., Yoshida, M., & Khochbin, S. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00542-x · Cited by 224

Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients

Osada, H., Tatematsu, Y., Saito, H., Yatabe, Y., Mitsudomi, T., & Takahashi, T. (2004) · International Journal of Cancer · doi:10.1002/ijc.20395 · Cited by 213

Isolation and Characterization of Mammalian HDAC10, a Novel Histone Deacetylase

Kao, H.-Y., Lee, C.-H., Komarov, A., Han, C. C., & Evans, R. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108931200 · Cited by 193

HDAC6 Deacetylase Activity Links the Tubulin Cytoskeleton with Immune Synapse Organization

Serrador, J. M., Cabrero, J. R., Sancho, D., Mittelbrunn, M., Urzainqui, A., & Sánchez‐Madrid, F. (2004) · Immunity · doi:10.1016/s1074-7613(04)00078-0 · Cited by 193

Analysis of the Deubiquitinating Enzymes of the Yeast Saccharomyces cerevisiae

Amerik, A. Y., Li, S., & Hochstrasser, M. (2000) · Biological Chemistry · doi:10.1515/bc.2000.121 · Cited by 190

Aberrant expression of histone deacetylase 6 in oral squamous cell carcinoma

Sakuma, T., Uzawa, K., Onda, T., Shiiba, M., Yokoe, H., Shibahara, T., & Tanzawa, H. (2006) · International Journal of Oncology · doi:10.3892/ijo.29.1.117 · Cited by 185

Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain

Tong, J. J. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.5.1114 · Cited by 181

Regulation of the Dynamics of hsp90 Action on the Glucocorticoid Receptor by Acetylation/Deacetylation of the Chaperone*

Murphy, P. J. M., Morishima, Y., Kovacs, J. J., Yao, T.-P., & Pratt, W. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506997200 · Cited by 167

Two Catalytic Domains Are Required for Protein Deacetylation

Zhang, Y., Gilquin, B., Khochbin, S., & Matthias, P. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.c500241200 · Cited by 161

Role of the Tetradecapeptide Repeat Domain of Human Histone Deacetylase 6 in Cytoplasmic Retention

Bertos, N., Gilquin, B., Chan, G. K. T., Yen, T. J., Khochbin, S., & Yang, X. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408583200 · Cited by 160

Histone deacetylase inhibitors prevent exocytosis of interleukin-1β-containing secretory lysosomes: role of microtubules

Carta, S., Tassi, S., Semino, C., Fossati, G., Mascagni, P., Dinarello, C. A., & Rubartelli, A. (2006) · Blood · doi:10.1182/blood-2006-03-014126 · Cited by 151

Characterization of the two catalytic domains in histone deacetylase 6

Zou, H., Wu, Y., Navre, M., & Sang, B. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.12.144 · Cited by 144

Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities

Wang, Q., Song, C., & Li, C.-C. H. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02840-1 · Cited by 142

Positive and Negative Regulation of the Innate Antiviral Response and Beta Interferon Gene Expression by Deacetylation

Nusinzon, I., & Horvath, C. M. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.8.3106-3113.2006 · Cited by 139

Isolation and Characterization of a Novel Class II Histone Deacetylase, HDAC10

Fischer, D. D., Cai, R. L., Bhatia, U., Asselbergs, F. A. M., Song, C., Terry, R., Trogani, N., Widmer, R., Atadja, P. W., & Cohen, D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108055200 · Cited by 133

Deactylase Inhibitors Disrupt Cellular Complexes Containing Protein Phosphatases and Deacetylases

Brush, M., Guardiola, A. R., Connor, J. H., Yao, T., & Shenolikar, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310997200 · Cited by 128

Histone Deacetylase 6 Regulates Human Immunodeficiency Virus Type 1 Infection

Valenzuela-Fernández, A., Álvarez, S., Gordón‐Alonso, M., Barrero-Villar, M., Ursa, Á., Cabrero, J. R., Fernández, G., Naranjo‐Suarez, S., Yáñez‐Mó, M., Serrador, J. M., et al. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-04-0354 · Cited by 126

The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Marcus, A. I., Zhou, J., O’Brate, A., Hamel, E., Wong, J. Y. Y., Nivens, M. C., El‐Naggar, A. K., Yao, T., Khuri, F. R., & Giannakakou, P. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3757 · Cited by 109

Proteomic analysis of organ‐specific post‐translational lysine‐acetylation and ‐methylation in mice by use of anti‐acetyllysine and ‐methyllysine mouse monoclonal antibodies

Iwabata, H., Yoshida, M., & Komatsu, Y. (2005) · PROTEOMICS · doi:10.1002/pmic.200500042 · Cited by 97

Lymphocyte Chemotaxis Is Regulated by Histone Deacetylase 6, Independently of Its Deacetylase Activity

Cabrero, J. R., Serrador, J. M., Barreiro, O., Mittelbrunn, M., Naranjo-Suárez, S., Martín-Cófreces, N., Vicente-Manzanares, M., Mazitschek, R., Bradner, J. E., Ávila, J., et al. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-01-0008 · Cited by 95

A Novel Action of Histone Deacetylase Inhibitors in a Protein Aggresome Disease Model

Corcoran, L., Mitchison, T. J., & Liu, Q. (2004) · Current Biology · doi:10.1016/j.cub.2004.03.003 · Cited by 87

Prediction of prognosis of estrogen receptor‐positive breast cancer with combination of selected estrogen‐regulated genes

Yoshida, N., Omoto, Y., Inoue, A., Eguchi, H., Kobayashi, Y., Kurosumi, M., Saji, S., Suemasu, K., Okazaki, T., Nakachi, K., et al. (2004) · Cancer Science · doi:10.1111/j.1349-7006.2004.tb03239.x · Cited by 78

Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone

Hurst, D. R., Mehta, A., Moore, B. P., Phadke, P. A., Meehan, W. J., Accavitti, M. A., Shevde, L. A., Hopper, J. E., Xie, Y., Welch, D. R., et al. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.08.005 · Cited by 69

NF-κB inhibits transcription of the H+-K+-ATPase α2-subunit gene: role of histone deacetylases

Zhang, W., & Kone, B. C. (2002) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00156.2002 · Cited by 69

dSIR2 and dHDAC6: Two Novel, Inhibitor-Resistant Deacetylases in Drosophila melanogaster

Barlow, A. L., van Drunen, C. M., Johnson, C. A., Tweedie, S., Bird, A. P., & Turner, B. M. (2001) · Experimental Cell Research · doi:10.1006/excr.2001.5162 · Cited by 65

Multiple Histone Deacetylases and the CREB-binding Protein Regulate Pre-mRNA 3′-End Processing

Shimazu, T., Horinouchi, S., & Yoshida, M. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m609745200 · Cited by 58

The viral control of cellular acetylation signaling

Caron, C., Col, E., & Khochbin, S. (2002) · BioEssays · doi:10.1002/bies.10202 · Cited by 46

Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection

Mosley, A. J., Meekings, K. N., McCarthy, C., Shepherd, D., Cerundolo, V., Mazitschek, R., Tanaka, Y., Taylor, G. P., & Bangham, C. R. M. (2006) · Blood · doi:10.1182/blood-2006-03-013235 · Cited by 39

Farnesyltransferase Inhibitors Reverse Taxane Resistance

Marcus, A. I., O’Brate, A., Buey, R. M., Zhou, J., Thomas, S. L., Khuri, F. R., Andreu, J. M., Díaz, F., & Giannakakou, P. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0699 · Cited by 36

RhoA/ROCK Activation by Growth Hormone Abrogates p300/Histone Deacetylase 6 Repression of Stat5-mediated Transcription

Ling, L., & Lobie, P. E. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400601200 · Cited by 32

A Conserved Motif Common to the Histone Acetyltransferase Esa1 and the Histone Deacetylase Rpd3

Adachi, N., Kimura, A., & Horikoshi, M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204640200 · Cited by 19

Lysine 3 acetylation regulates the phosphorylation of yeast 6-phosphofructo-2-kinase under hypo-osmotic stress

Dihazi, H., Keßler, R., Muller, G. A., & Eschrich, K. (2005) · Biological Chemistry · doi:10.1515/bc.2005.104 · Cited by 17

Basic research for hormone-sensitivity of breast cancer

Hayashi, S., & Yamaguchi, Y. (2006) · Breast Cancer · doi:10.2325/jbcs.13.123 · Cited by 7

Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes

Wang, Z., Zang, C., Cui, K., Schones, D. E., Barski, A., Peng, W., & Zhao, K. (2009) · Cell · doi:10.1016/j.cell.2009.06.049 · Cited by 1,344

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

Yang, X., & Seto, E. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2346 · Cited by 1,277

HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention

Yang, X.-J., & Seto, E. (2007) · Oncogene · doi:10.1038/sj.onc.1210599 · Cited by 940

The world of protein acetylation

Drazic, A., Myklebust, L. M., Ree, R., & Arnesen, T. (2016) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2016.06.007 · Cited by 847

Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A

Butler, K. V., Kalin, J., Brochier, C., Vistoli, G., Langley, B., & Kozikowski, A. P. (2010) · Journal of the American Chemical Society · doi:10.1021/ja102758v · Cited by 801

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