The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Exploring natural silk protein sericin for regenerative medicine: an injectable, photoluminescent, cell-adhesive 3D hydrogel
Open accessAbstract
Sericin, a major component of silk, has a long history of being discarded as a waste during silk processing. The value of sericin for tissue engineering is underestimated and its potential application in regenerative medicine has just begun to be explored. Here we report the successful fabrication and characterization of a covalently-crosslinked 3D pure sericin hydrogel for delivery of cells and drugs. This hydrogel is injectable, permitting its implantation through minimally invasive approaches. Notably, this hydrogel is found to exhibit photoluminescence, enabling bioimaging and in vivo tracking. Moreover, this hydrogel system possesses excellent cell-adhesive capability, effectively promoting cell attachment, proliferation and long-term survival of various types of cells. Further, the sericin hydrogel releases bioactive reagents in a sustained manner. Additionally, this hydrogel demonstrates good elasticity, high porosity, and pH-dependent degradation dynamics, which are advantageous for this sericin hydrogel to serve as a delivery vehicle for cells and therapeutic drugs. With all these unique features, it is expected that this sericin hydrogel will have wide utility in the areas of tissue engineering and regenerative medicine.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Alginate hydrogels as synthetic extracellular matrix materials
Rowley, J. A., Madlambayan, G., & Mooney, D. J. (1999) · Biomaterials · doi:10.1016/s0142-9612(98)00107-0 · Cited by 2,342
The Use and Misuse of FTIR Spectroscopy in the Determination of Protein Structure
Jackson, M., & Mantsch, H. H. (1995) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409239509085140 · Cited by 2,037
Topics in Fluorescence Spectroscopy
(2003) · Topics in Fluorescence Spectroscopy · doi:10.1007/0-306-47947-8 · Cited by 1,578
Controlling the Porosity and Microarchitecture of Hydrogels for Tissue Engineering
Annabi, N., Nichol, J. W., Zhong, X., Ji, C., Koshy, S., Khademhosseini, A., & Dehghani, F. (2010) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2009.0639 · Cited by 1,308
In vivo molecular and cellular imaging with quantum dots
Gao, X., Yang, L., Petros, J. A., Marshall, F. F., Simons, J. W., & Nie, S. (2005) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2004.11.003 · Cited by 1,211
The basics and underlying mechanisms of mucoadhesion
SMART, J. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.07.001 · Cited by 1,167
Biological applications of quantum dots
Jamieson, T., Bakhshi, R., Petrova, D., Pocock, R., Imani, M., & Seifalian, A. M. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.014 · Cited by 1,107
Biodegradable polymeric scaffolds for musculoskeletal tissue engineering
Agrawal, C. M., & Ray, R. B. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(200105)55:2<141::aid-jbm1000>3.0.co;2-j · Cited by 1,052
Actin stress fibers – assembly, dynamics and biological roles
Tojkander, S., Gateva, G., & Lappalainen, P. (2012) · Journal of Cell Science · doi:10.1242/jcs.098087 · Cited by 900
Microengineered hydrogels for tissue engineering
Khademhosseini, A., & Langer, R. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.021 · Cited by 830
Cited by
Hydrogel scaffolds for tissue engineering: the importance of polymer choice
Spicer, C. D. (2020) · Polymer Chemistry · doi:10.1039/c9py01021a · Cited by 527
Zhang, F.-X., Liu, P., Ding, W., Meng, Q.-B., Su, D.-H., Zhang, Q.-C., Lian, R.-X., Yu, B.-Q., Zhao, M.-D., Dong, J., et al. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121169 · Cited by 328
Self-citationProtein Nanoparticles: Promising Platforms for Drug Delivery Applications
Jain, A., Singh, S. K., Arya, S. K., Kundu, S. C., & Kapoor, S. (2018) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b01098 · Cited by 308
Self-citationMulticolor Fluorescent Polymeric Hydrogels
Wei, S., Li, Z., Lu, W., Liu, H., Zhang, J., Chen, T., & Tang, B. Z. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202007506 · Cited by 281
Self-citation
Metadata
- Authors
- Wang, Z., Zhang, Y., Zhang, J., Huang, L., Liu, J., Li, Y., Zhang, G., Kundu, S. C., & Wang, L.
- Venue
- Scientific Reports
- Published
- 2014-11-20
- Volume
- 4
- Issue
- 1
- Pages
- 7064-7064
- ISSN
- 2045-2322 (ISSN-L)
- OpenAlex
- W2033689464
- Cited by
- 289
- References
- 47
- FWCI
- 4.43
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Exploring natural silk protein sericin for regenerative medicine: an injectable, photoluminescent, cell-adhesive 3D hydrogel. https://app.cochat.ai/papers/10.1038/srep07064
- The paper
- Wang, Z., Zhang, Y., Zhang, J., Huang, L., Liu, J., Li, Y., Zhang, G., Kundu, S. C., & Wang, L. (2014). Exploring natural silk protein sericin for regenerative medicine: an injectable, photoluminescent, cell-adhesive 3D hydrogel. Scientific Reports. https://doi.org/10.1038/srep07064
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
