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Genetic affinities of the Jewish populations of India

Chaubey, Gyaneshwer, Singh, Manvendra, Rai, Niraj, Kariappa, Mini, Singh, Kamayani, Singh, Ashish, Pratap Singh, Deepankar, Tamang, Rakesh, Selvi Rani, Deepa, Reddy, Alla G., Kumar Singh, Vijay, Singh, Lalji, Thangaraj, Kumarasamy·2016·Scientific Reports
DOI 10.1038/srep19166PMC PMC4725824
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Abstract

Due to the lack of written records or inscription, the origin and affiliation of Indian Jewish populations with other world populations remain contentious. Previous genetic studies have found evidence for a minor shared ancestry of Indian Jewish with Middle Eastern (Jewish) populations. However, these studies (relied on limited individuals), haven’t explored the detailed temporal and spatial admixture process of Indian Jewish populations with the local Indian populations. Here, using large sample size with combination of high resolution biparental (autosomal) and uniparental markers (Y chromosome and mitochondrial DNA), we reconstructed genetic history of Indian Jewish by investigating the patterns of genetic diversity. Consistent with the previous observations, we detected minor Middle Eastern specific ancestry component among Indian Jewish communities, but virtually negligible in their local neighbouring Indian populations. The temporal test of admixture suggested that the first admixture of migrant Jewish populations from Middle East to South India (Cochin) occurred during fifth century. Overall, we concluded that the Jewish migration and admixture in India left a record in their genomes, which can link them to the ‘Jewish Diaspora’.

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Crossref · 10.1038/srep19166

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Figures

Figure 1 The settlement of Jewish populations in Indian Subcontinent. Indian Jewish samples collected in present study are highlighted by maroon dots. The map was modified from the Wikipedia (https://en.wikipedia.org/wiki/File:India-locator-map-blank.svg).
Figure 1 The settlement of Jewish populations in Indian Subcontinent. Indian Jewish samples collected in present study are highlighted by maroon dots. The map was modified from the Wikipedia (https://en.wikipedia.org/wiki/File:India-locator-map-blank.svg).CC BY · PubMed Central
Figure 2 (a) Mean pairwise Fst comparison of Indian Jewish with other regional populations obtained from the autosomal SNP data. (b) Principal component analysis (PCA) of the combined autosomal SNP data of individuals from Eurasia.
Figure 2 (a) Mean pairwise Fst comparison of Indian Jewish with other regional populations obtained from the autosomal SNP data. (b) Principal component analysis (PCA) of the combined autosomal SNP data of individuals from Eurasia.CC BY · PubMed Central
Figure 3 Results of the populationwise unsupervised ‘Structure-like’ ADMIXTURE analysis (K = 7) of world population projecting various Jewish populations.
Figure 3 Results of the populationwise unsupervised ‘Structure-like’ ADMIXTURE analysis (K = 7) of world population projecting various Jewish populations.CC BY · PubMed Central
Figure 4 Comparison of the mean sharing of chunklengths of Indian Jewish vs Indian Dravidian neighbours received from Eurasian populations.
Figure 4 Comparison of the mean sharing of chunklengths of Indian Jewish vs Indian Dravidian neighbours received from Eurasian populations.CC BY · PubMed Central
Figure 5 The placement of various Indian Jewish groups in the PC1 vs. PC2 analysis obtained from haplogroup frequencies for mtDNA; (a) and Y chromosome, (b) within other Eurasian populations.
Figure 5 The placement of various Indian Jewish groups in the PC1 vs. PC2 analysis obtained from haplogroup frequencies for mtDNA; (a) and Y chromosome, (b) within other Eurasian populations.CC BY · PubMed Central

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Citations

Cites

Show all 6 references

Research works printed but not linked: 33

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Cited by

Metadata

Authors
Chaubey, G., Singh, M., Rai, N., Kariappa, M., Singh, K., Singh, A., Pratap Singh, D., Tamang, R., Selvi Rani, D., Reddy, A. G., Kumar Singh, V., Singh, L., & Thangaraj, K.
Venue
Scientific Reports
Publisher
Springer Science and Business Media LLC
Published
2016-01-13
Volume
6
Issue
1
ISSN
2045-2322
DOI
10.1038/srep19166
PMC
PMC4725824
Cited by
19
References
6
Language
en
Update notices
correction (2016-05-23)
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