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Per-polyfluoroalkyl substances (PFAS) as thyroid disruptors: is there evidence for multi-transgenerational effects?

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zPACT: Tissue Clearing and Immunohistochemistry on Juvenile Zebrafish Brain

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X-FaCT: Xenopus-Fast Clearing Technique

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Industrial Applications, Environmental Fate, Human Exposure, and Health Effects of PFAS

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Assessment of chemical mixtures using biomarkers of combined biological activity: A screening study in human placentas

Rodríguez‐Carrillo, A., Rosenmai, A. K., Mustieles, V., Couderq, S., Fini, J., Vela-Soria, F., Molina-Molina, J.-M., Ferrando-Marco, P., Wielsøe, M., Long, M., et al. (2021) · Reproductive Toxicology · doi:10.1016/j.reprotox.2021.01.002 · Cited by 18 · see citing works

Electrochemical degradation of diclofenac generates unexpected thyroidogenic transformation products: Implications for environmental risk assessment

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The pyriproxyfen metabolite, 4′–OH–PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection.

Vancamp, P., Špirhanzlová, P., Sébillot, A., Butruille, L., Gothié, J. M., Mével, S. L., Leemans, M., Wejaphikul, K., Meima, M. E., Mughal, B. B., et al. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.117654 · Cited by 18 · see citing works

Overview of sources, Fate, and Impact of Endocrine Disrupting Compounds in Environment and Assessment of their Regulatory Policies across different continents

Singh, A., Singh, G., Singh, P., & Mishra, V. K. (2023) · Total Environment Research Themes · doi:10.1016/j.totert.2023.100071 · Cited by 16 · see citing works

Evaluation of Effective and Practical Euthanasia Methods for Larval African Clawed Frogs (Xenopus laevis)

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From Cohorts to Molecules: Adverse Impacts of Endocrine Disrupting MixturesPreprint

Birgersson, L., Borbély, G., Caporale, N., Germain, P., Leemans, M., Rendel, F., D’Agostino, G. A., Bressan, R. B., Cavallo, F., Chorev, N. E., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/206664 · Cited by 13 · see citing works

Thyroid Disrupting Chemicals in Mixture Perturb Thymocyte Differentiation in Xenopus laevis Tadpoles

McGuire, C. C., Lawrence, B. P., & Robert, J. (2021) · Toxicological Sciences · doi:10.1093/toxsci/kfab029 · Cited by 12 · see citing works

A Mixture of Chemicals Found in Human Amniotic Fluid Disrupts Brain Gene Expression and Behavior in Xenopus laevis

Leemans, M., Špirhanzlová, P., Couderq, S., Mével, S. L., Grimaldi, A. G., Duvernois‐Berthet, E., DEMENEIX, B. A., & Fini, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032588 · Cited by 11 · see citing works

In vitro assays for characterization of distinct multiple catalytic activities of thyroid peroxidase using LC-MS/MS

Tater, A., Gupta, A., Upadhyay, G., Deshpande, A., Date, R., & Tamboli, I. Y. (2021) · Current Research in Toxicology · doi:10.1016/j.crtox.2021.01.001 · Cited by 11 · see citing works

Opportunities in Assessing and Regulating Organohalogen Flame Retardants (OFRs) as a Class in Consumer Products

Chen, X., Birnbaum, L. S., Babich, M. A., de Boer, J., White, K. W., Barone, S., Fehrenbacher, C., & Stapleton, H. M. (2024) · Environmental Health Perspectives · doi:10.1289/ehp12725 · Cited by 10 · see citing works

Sunscreen pollution is abated during the COVID-19 “Anthropause” of 2020 in two U.S. National Parks: Cape Lookout National Seashore and Kaloko-Honokōhau National Historical Park

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Clearing techniques for visualizing the nervous system in development, injury, and disease

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Evaluating Thyroid Disrupting Chemicals In Vivo Using Xenopus laevis

Mughal, B. B., DEMENEIX, B. A., & Fini, J. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7902-8_15 · Cited by 9 · see citing works

Is the Observed Decrease in Body Temperature During Industrialization Due to Thyroid Hormone-Dependent Thermoregulation Disruption?

Vancamp, P., & DEMENEIX, B. A. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00470 · Cited by 9 · see citing works

Exposure to prenatal PCBs shifts the timing of neurogenesis in the hypothalamus of developing rats

Hernandez, M. E., Kunkel, M. N., & Gore, A. C. (2020) · Journal of Experimental Zoology Part A Ecological and Integrative Physiology · doi:10.1002/jez.2404 · Cited by 8 · see citing works

Les perturbateurs thyroïdiens et leurs conséquences sur le développement cérébral

Fini, J., & DEMENEIX, B. A. (2019) · Biologie Aujourd hui · doi:10.1051/jbio/2019009 · Cited by 8 · see citing works

Following Endocrine-Disrupting Effects on Gene Expression in Xenopus laevisPreprint

Špirhanzlová, P., Leemans, M., DEMENEIX, B. A., & Fini, J. (2018) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot098301 · Cited by 8 · see citing works

Chemical contaminants — a toxic mixture for neurodevelopment

Hernandez, M. E., & Gore, A. C. (2017) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2017.40 · Cited by 7 · see citing works

The interplay of the mammalian brain and thyroid hormones, and the threat of endocrine-disrupting chemicals

Dsouki, N. A., Pereira, B. F., da Silva, R. G., Rodrigues, V. G., Brito, R. D. S., Kizys, M. M. L., Chiamolera, M. I., Maciel, R. M., Serrano-Nascimento, C., & Giannocco, G. (2024) · Endocrines · doi:10.3390/endocrines5040036 · Cited by 6 · see citing works

Transcriptome analysis of the response to thyroid hormone in Xenopus neural stem and progenitor cells

Cordero‐Véliz, C., Larraı́n, J., & Faunes, F. (2022) · Developmental Dynamics · doi:10.1002/dvdy.535 · Cited by 6 · see citing works

The pyriproxyfen metabolite 4'OH- pyriproxyfen disrupts thyroid hormone signaling and enhances Musashi-1 levels in neuroprogenitors.Preprint

Špirhanzlová, P., Mével, S. L., Wejaphikul, K., Mughal, B. B., Gothié, J. M., Sébillot, A., Butruille, L., Leemans, M., Visser, T. J., Remaud, S., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/352088 · Cited by 6 · see citing works

Understanding the plastic-associated endocrine-disrupting chemicals in India: Environmental contamination, health impacts and regulatory challenges

Tripathi, D., Singh, S., & Ahamad, K. U. (2025) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2025.118453 · Cited by 6 · see citing works

Outcome of the public consultation on the draft scientific report on the cumulative dietary risk characterisation of pesticides that have acute effects on the nervous system

(EFSA), E. F. S. A. (2020) · EFSA Supporting Publications · doi:10.2903/sp.efsa.2020.en-1835 · Cited by 4 · see citing works

Environmental influences on brain aging

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Sand Goby—An Ecologically Relevant Species for Behavioural Ecotoxicology

Asnicar, D., Ašmonaitė, G., Birgersson, L., Kvarnemo, C., Svensson, O., & Sturve, J. (2018) · Fishes · doi:10.3390/fishes3010013 · Cited by 4 · see citing works

Intracytoplasmic Sperm Injection Using 20-Year-Old Cryopreserved Sperm Results in Normal, Viable, and Reproductive Offspring in Xenopus laevis: A Major Pioneering Achievement for Amphibian Conservation

Péricard, L., Mével, S. L., Marquis, O., Locatelli, Y., & Coen, L. (2025) · Animals · doi:10.3390/ani15131941 · Cited by 3 · see citing works

Environmental Factors

Köhrle, J. (2022) · doi:10.1093/med/9780198870197.003.0048 · Cited by 3 · see citing works

Environmental Factors and Female Reproduction

Fénichel, P., & Rougier, C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.64950-4 · Cited by 3 · see citing works

Overlapping action of T3 and T4 during Xenopus laevis development

Tribondeau, A., Pasquier, D. D., Benchouaia, M., Blugeon, C., Buisine, N., & Sachs, L. M. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1360188 · Cited by 2 · see citing works

Long-term exposure of mice to sodium fluoride and to a mixture of endocrine disruptors causes tooth enamel and retina abnormalities associated with changes in hepatic metabolism

Picard, É., Palma, F. D. E. D., Loiodice, S., Carbonnier, V., Achiedo, S., Mimoun, N., Diluxe, M., Doublier, S., Durand, S., Bourgin, M., et al. (2025) · Environment International · doi:10.1016/j.envint.2025.109861 · Cited by 2 · see citing works

Interdisciplinary strategies to assess the relationship between exposure to complex chemical mixtures and thyroid hormone system disruption

Margalef, M., Meijer, J., Lamoree, M. H., & Hamers, T. (2023) · Current Opinion in Toxicology · doi:10.1016/j.cotox.2023.100421 · Cited by 2 · see citing works

Underestimated environmental factors contributing to autism spectrum disorders

Fini, J., Leemans, M., & DEMENEIX, B. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818466-0.00004-6 · Cited by 1 · see citing works

Importance of fetal thyroid hormone signaling to brain development: a window of vulnerability for endocrine disruption

DEMENEIX, B. A., Fini, J., Leemans, M., Mughal, B. B., Mével, S. L., & Spirhanslova, P. (2018) · Toxicology Letters · doi:10.1016/j.toxlet.2018.06.1204

Brain and behavior.

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Top 5 Arthrose du 35e congrès SFR

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Les perturbateurs des hormones thyroïdiennes : comment estimer leurs impacts sur la santé humaine et l’environnement ?

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Environmental challenges to thyroid homeostasis: Combined effects of iodine deficiency and endocrine disruption

Rannaud-Bartaire, P., Herranen, A., Levi, G., DEMENEIX, B. A., & Fini, J. (2026) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2026.100597

Effects of endocrine disruptors on Phallusia mammillata embryonic development

Gomes, I. D. L. (2018) · doi:10.70675/c94fdd4cz73bez40cezb5a2zd71a6afdee58

Characterization of dental defects in mice exposed to phthalates and bisphenols as early marker of exposure to endocrine disrupting chemicals

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Identification of biomarkers of effect following exposure to endocrine disrupting chemicals in Xenopus laevis and their relevance for human health

Couderq, S. (2022) · doi:10.70675/11ee966az2d84z47a4z99b1z77e79bf324eb

Study of Whole Mounts and Sections of Developmental Stages of the Frog

Senrung, A., & Bharti, A. C. (2026) · Springer eBooks · doi:10.1007/978-981-95-7269-4_2

Targeting oligodendrocytes in developmental neurotoxicity: A systematic literature review

Mohammed, V., Persson, C., Awoga, R. A., & Forsby, A. (2026) · NeuroToxicology · doi:10.1016/j.neuro.2026.103557

A Mixture of Chemicals Found in Human Amniotic Fluid Disrupts Brain Gene Expression and Behavior in Xenopus laevis

Leemans, M., Špirhanzlová, P., Couderq, S., Mével, S. L., Grimaldi, A. G., Duvernois‐Berthet, E., DEMENEIX, B. A., & Fini, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032588 · Cited by 11 · see citing works

Chemical contaminants — a toxic mixture for neurodevelopment

Hernandez, M. E., & Gore, A. C. (2017) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2017.40 · Cited by 7 · see citing works

Mixtures of xenobiotics found in human fluid modify embryonic thyroid hormone signaling and brain development

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Thyroid-disrupting chemicals and brain development: an update

Mughal, B. B., Fini, J., & DEMENEIX, B. A. (2018) · Endocrine Connections · doi:10.1530/ec-18-0029 · Cited by 170 · see citing works

Thyroid hormone action and disruption in the brain : xenopus as a model to study disruption of thyroid hormone availability on early brain development

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