Retraction Note: A significant causal association between C-reactive protein levels and schizophrenia
Open accessAbstract
Correction to: Scientific Reports 6: Article number: 26105; published online: 19 May 2016; updated: 21 February 2018 The authors are retracting this Article. The Article comprises three parts: a case-control study; a meta-analysis of case-control studies; and Mendelian randomization (MR) analyses (two datasets; a Japanese dataset and a public genome-wide association study [GWAS]-pooled dataset).
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Empirical investigations in European populations have shown that associations between genetic variants and many traits are no stronger than would be expected due to chance alone.
“Empirical investigations in European populations have shown that associations between genetic variants and many traits are no stronger than would be expected due to chance alone 46, 47 .”
From Guidelines for performing Mendelian randomization investigations (2020) · cites this paper as [47]
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The MR-Base platform supports systematic causal inference across the human phenome
Hemani, G., Zheng, J., Elsworth, B., Wade, K. H., Haberland, V., Baird, D., Laurin, C., Burgess, S., Bowden, J., Langdon, R., et al. (2018) · eLife · doi:10.7554/elife.34408 · Cited by 7,959 · see citing works
“It has been shown that discrepant results can easily arise using identical data because of potential errors of implementation ( Hartwig et al., 2016 ; Hartwig et al., 2017 ; Inoshita et al., 2018 ).”
ResultGuidelines for performing Mendelian randomization investigations
Burgess, S., Smith, G. D., Davies, N. M., Dudbridge, F., Gill, D., Glymour, M. M., Hartwig, F. P., Holmes, M. V., Minelli, C., Relton, C. L., et al. (2019) · Wellcome Open Research · doi:10.12688/wellcomeopenres.15555.1 · Cited by 1,816 · see citing works
Guidelines for performing Mendelian randomization investigations
Burgess, S., Davey Smith, G., Davies, N. M., Dudbridge, F., Gill, D., Glymour, M. M., Hartwig, F. P., Holmes, M. V., Minelli, C., Relton, C. L., et al. (2020) · Wellcome Open Research · doi:10.12688/wellcomeopenres.15555.2 · Cited by 1,273 · see citing works
Davey Smith, G., Holmes, M. V., Davies, N. M., & Ebrahim, S. (2020) · European Journal of Epidemiology · doi:10.1007/s10654-020-00622-7 · Cited by 287 · see citing works
Approaches and advances in the genetic causes of autoimmune disease and their implications
Inshaw, J. R. J., Cutler, A. J., Burren, O. S., Stefana, M. I., & Todd, J. A. (2018) · Nature Immunology · doi:10.1038/s41590-018-0129-8 · Cited by 70 · see citing works
Lin, B. D., Alkema, A., Peters, T., Zinkstok, J., Libuda, L., Hebebrand, J., Antel, J., Hinney, A., Cahn, W., Adan, R. A. H., et al. (2019) · International Journal of Epidemiology · doi:10.1093/ije/dyz176 · Cited by 57 · see citing works
Mendelian randomisation at 20 years: how can it avoid hubris, while achieving more?
Smith, G. D., & Ebrahim, S. B. J. (2023) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(23)00348-0 · Cited by 52 · see citing works
Characteristics of global retractions of schizophrenia-related publications: A bibliometric analysis
Chen, P., Li, X.-H., Su, Z., Tang, Y., Ma, Y., Ng, C. H., & Xiang, Y. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.937330 · Cited by 16 · see citing works
“Other studies were retracted due to incomplete data (38), lack of original data (39), or errors in data processing that led to biased conclusions (40).”
BackgroundMonitoring inflammation in psychiatry: Caveats and advice
Khalfallah, O., Barbosa, S., Martinuzzi, E., Davidovic, L., Yolken, R. H., & Glaichenhaus, N. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.09.003 · Cited by 8 · see citing works
Fifteen years of epidemiology in BMC Medicine
Lawlor, D. A. (2019) · BMC Medicine · doi:10.1186/s12916-019-1407-5 · Cited by 5 · see citing works
- Authors
- Inoshita, M., Numata, S., Tajima, A., Kinoshita, M., Umehara, H., Nakataki, M., Ikeda, M., Maruyama, S., Yamamori, H., Kanazawa, T., Shimodera, S., Hashimoto, R., Imoto, I., Yoneda, H., Iwata, N., & Ohmori, T.
- ORCID
- Venue
- Scientific Reports
- Published
- 2018-02-21
- Volume
- 8
- Issue
- 1
- Pages
- 46947-46947
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC5820535
- OpenAlex
- W2789128591
- Cited by
- 10
- References
- 0
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 2
- Type
- retraction
- Language
- en
- Status
- Retracted
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- C-reactive protein, schizophrenia, Mendelian randomization, case-control study, meta-analysis, genome-wide association study
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