The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Influence of length on cytotoxicity of multi-walled carbon nanotubes against human acute monocytic leukemia cell line THP-1 in vitro and subcutaneous tissue of rats in vivo
Abstract
Carbon nanotubes (CNTs) are single- or multi-cylindrical graphene structures that possess diameters of a few nanometers, while the length can be up to a few micrometers. These could have unusual toxicological properties, in that they share intermediate morphological characteristics of both fibers and nanoparticles. To date, no detailed study has been carried out to determine the effect of length on CNT cytotoxicity. In this paper, we investigated the activation of the human acute monocytic leukemia cell line THP-1 in vitro and the response in subcutaneous tissue in vivo to CNTs of different lengths. We used 220 nm and 825 nm-long CNT samples for testing, referred to as “220-CNTs” and “825-CNTs”, respectively. 220-CNTs and 825-CNTs induced human monocytes in vitro, although the activity was significantly lower than that of microbial lipopeptide and lipopolysaccharide, and no activity appeared following variation in the length of CNTs. On the other hand, the degree of inflammatory response in subcutaneous tissue in rats around the 220-CNTs was slight in comparison with that around the 825-CNTs. These results indicated that the degree of inflammation around 825-CNTs was stronger than that around 220-CNTs since macrophages could envelop 220-CNTs more readily than 825-CNTs. However, no severe inflammatory response such as necrosis, degeneration or neutrophil infiltration in vivo was observed around both CNTs examined throughout the experimental period.
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Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)
Tsuchiya, S., Yamabe, M., Yamaguchi, Y., Kobayashi, Y., Konno, T., & Tada, K. (1980) · International Journal of Cancer · doi:10.1002/ijc.2910260208 · Cited by 2,254
The potential environmental impact of engineered nanomaterials
Colvin, V. L. (2003) · Nature Biotechnology · doi:10.1038/nbt875 · Cited by 2,158
Lam, C.-W. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg243 · Cited by 1,991
Comparative Pulmonary Toxicity Assessment of Single-wall Carbon Nanotubes in Rats
Warheit, D. B. (2003) · Toxicological Sciences · doi:10.1093/toxsci/kfg228 · Cited by 1,515
Pantarotto, D., Briand, J.-P., Prato, M., & Bianco, A. (2004) · Chemical Communications · doi:10.1039/b311254c · Cited by 1,102
Functionalized Carbon Nanotubes for Plasmid DNA Gene Delivery
Pantarotto, D., Singh, R., McCarthy, D., Erhardt, M., Briand, J., Prato, M., Kostarelos, K., & Bianco, A. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200460437 · Cited by 1,091
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Effect of single wall carbon nanotubes on human HEK293 cells
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Cited by
Singh, R., Pantarotto, D., Lacerda, L., Pastorin, G., Klumpp, C., Prato, M., Bianco, A., & Kostarelos, K. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509009103 · Cited by 1,043
Toxicology of nanoparticles: A historical perspective
Oberdörster, G., Stone, V., & Donaldson, K. (2007) · Nanotoxicology · doi:10.1080/17435390701314761 · Cited by 964
Minireview: Nanoparticles and the Immune System
Zolnik, B. S., González-Fernández, A., Sadrieh, N., & Dobrovolskaia, M. A. (2010) · Endocrinology · doi:10.1210/en.2009-1082 · Cited by 914
The degree and kind of agglomeration affect carbon nanotube cytotoxicity
WICK, P., MANSER, P., LIMBACH, L., DETTLAFFWEGLIKOWSKA, U., KRUMEICH, F., ROTH, S., STARK, W., & BRUININK, A. (2007) · Toxicology Letters · doi:10.1016/j.toxlet.2006.08.019 · Cited by 818
Nanodiamond Particles: Properties and Perspectives for Bioapplications
Schrand, A. M., Hens, S. A. C., & Shenderova, O. A. (2009) · Critical Reviews in Solid State and Materials Sciences · doi:10.1080/10408430902831987 · Cited by 802
Metadata
- Authors
- Sato, Y., Yokoyama, A., Shibata, K.-I., Akimoto, Y., Ogino, S.-I., Nodasaka, Y., Kohgo, T., Tamura, K., Akasaka, T., Uo, M., Motomiya, K., Jeyadevan, B., Ishiguro, M., Hatakeyama, R., Watari, F., & Tohji, K.
- Venue
- Molecular BioSystems
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-04-20
- Volume
- 1
- Issue
- 2
- Pages
- 176-182
- ISSN
- 1742-2051 (ISSN-L)
- 1742-206X
- OpenAlex
- W2129325343
- Cited by
- 351
- References
- 39
- FWCI
- 13.73
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sato, Y., Yokoyama, A., Shibata, K.-I., Akimoto, Y., Ogino, S.-I., Nodasaka, Y., Kohgo, T., Tamura, K., Akasaka, T., Uo, M., Motomiya, K., Jeyadevan, B., Ishiguro, M., Hatakeyama, R., Watari, F., & Tohji, K. (2005). Influence of length on cytotoxicity of multi-walled carbon nanotubes against human acute monocytic leukemia cell line THP-1 in vitro and subcutaneous tissue of rats in vivo. Molecular BioSystems. https://doi.org/10.1039/b502429c
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