The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Design of targeting ligands in medicinal inorganic chemistry
Abstract
This tutorial review will highlight recent advances in medicinal inorganic chemistry pertaining to the use of multifunctional ligands for enhanced effect. Ligands that adequately bind metal ions and also include specific targeting features are gaining in popularity due to their ability to enhance the efficacy of less complicated metal-based agents. Moving beyond the traditional view of ligands modifying reactivity, stabilizing specific oxidation states, and contributing to substitution inertness, we will discuss recent work involving metal complexes with multifunctional ligands that target specific tissues, membrane receptors, or endogenous molecules, including enzymes.
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Cites
Neurodegenerative diseases and oxidative stress
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Designed Multiple Ligands. An Emerging Drug Discovery Paradigm
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Paramagnetic lanthanide complexes as PARACEST agents for medical imaging
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The role of coordination chemistry in the development of target-specific radiopharmaceuticals
Liu, S. (2004) · Chemical Society Reviews · doi:10.1039/b309961j · Cited by 351
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Cited by
Ray, S., Mohan, R., Singh, J. K., Samantaray, M. K., Shaikh, M. M., Panda, D., & Ghosh, P. (2007) · Journal of the American Chemical Society · doi:10.1021/ja075889z · Cited by 656
Using coordination chemistry to design new medicines
Ronconi, L., & Sadler, P. J. (2007) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2006.11.017 · Cited by 608
van Rijt, S. H., & Sadler, P. J. (2009) · Drug Discovery Today · doi:10.1016/j.drudis.2009.09.003 · Cited by 592
Recent developments of gallic acid derivatives and their hybrids in medicinal chemistry: A review
AL Zahrani, N. A., El-Shishtawy, R. M., & Asiri, A. M. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.112609 · Cited by 346
Hannon, M. J. (2007) · Pure and Applied Chemistry · doi:10.1351/pac200779122243 · Cited by 313
Metadata
- Authors
- Storr, T., Thompson, K. H., & Orvig, C.
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2006
- Volume
- 35
- Issue
- 6
- Pages
- 534
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2113161125
- Cited by
- 326
- References
- 32
- FWCI
- 0.80
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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