The DOI matches its Crossref record; 165 of the 165 references it cites were found in a registry or an index.
A hitchhiker's guide to G-quadruplex ligands
Abstract
Over the past decade, nucleic acid chemists have seen the spectacular emergence of molecules designed to interact efficiently and selectively with a peculiar DNA structure named G-quadruplex. Initially derived from classical DNA intercalators, these G-quadruplex ligands progressively became the focal point of new excitement since they appear to inhibit selectively the growth of cancer cells thereby opening interesting perspectives towards the development of novel anti-cancer drugs. The present article aims to help researchers enter this exciting research field, and to highlight recent advances in the design of G-quadruplex ligands.
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1 retracted
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RetractedSpecific Association of Human Telomerase Activity with Immortal Cells and Cancer
Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Coviello, G. M., Wright, W. E., Weinrich, S. L., & Shay, J. W. (1994) · Science · doi:10.1126/science.7605428 · Cited by 7,091
Quadruplex DNA: sequence, topology and structure
Burge, S., Parkinson, G. N., Hazel, P., Todd, A. K., & Neidle, S. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl655 · Cited by 2,408
Siddiqui-Jain, A., Grand, C. L., Bearss, D. J., & Hurley, L. H. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.182256799 · Cited by 2,238
Prevalence of quadruplexes in the human genome
Huppert, J. L., & Balasubramanian, S. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki609 · Cited by 1,741
G‐Quartets 40 Years Later: From 5′‐GMP to Molecular Biology and Supramolecular Chemistry
Davis, J. T. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200300589 · Cited by 1,626
G-quadruplexes in promoters throughout the human genome
Huppert, J. L., & Balasubramanian, S. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkl1057 · Cited by 1,356
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Highly prevalent putative quadruplex sequence motifs in human DNA
Todd, A. K. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki553 · Cited by 978
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
Darnell, J. C., Jensen, K. B., Jin, P., Brown, V., Warren, S. T., & Darnell, R. B. (2001) · Cell · doi:10.1016/s0092-8674(01)00566-9 · Cited by 952
Cited by
The Structure and Function of DNA G-Quadruplexes
Spiegel, J., Adhikari, S., & Balasubramanian, S. (2020) · Trends in Chemistry · doi:10.1016/j.trechm.2019.07.002 · Cited by 920
“with G-tetrads, a positive charge or basic groups to bind to loops or grooves of the G4, and steric bulk to prevent intercalation with double-stranded DNA [33].”
BackgroundRodriguez, R., Müller, S., Yeoman, J. A., Trentesaux, C., Riou, J.-F., & Balasubramanian, S. (2008) · Journal of the American Chemical Society · doi:10.1021/ja805615w · Cited by 517
Nepali, K., Sharma, S., Sharma, M., Bedi, P. M. S., & Dhar, K. L. (2014) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2014.03.018 · Cited by 435
The role of G-quadruplex in RNA metabolism: involvement of FMRP and FMR2P
Melko, M., & Bardoni, B. (2010) · Biochimie · doi:10.1016/j.biochi.2010.05.018 · Cited by 74
Natural products targeting telomere maintenance
Chen, J. L.-Y., Sperry, J., Ip, N. Y., & Brimble, M. A. (2011) · MedChemComm · doi:10.1039/c0md00241k · Cited by 41
Metadata
- Authors
- Monchaud, D., & Teulade-Fichou, M.-P.
- Venue
- Org. Biomol. Chem.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2008
- Volume
- 6
- Issue
- 4
- Pages
- 627-636
- ISSN
- 1477-0520 (ISSN-L)
- 1477-0539
- OpenAlex
- W2053166926
- Cited by
- 788
- References
- 165
- FWCI
- 15.09
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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