The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Achievements and open questions in the self-reproduction of vesicles and synthetic minimal cells
Abstract
Supramolecular chemistry was enriched, about twenty years ago, by the discovery of the self-reproduction of micelles and vesicles. The dynamic aspects and complexity of these systems makes them good models for biological compartments. For example, the self-reproduction of vesicles suggests that the growth in size and number of a vesicle population resembles the pattern of living cells in several aspects, but it take place solely due to physical forces. Several reports demonstrate that reverse micelles, micelles, sub-micrometric and giant vesicles can self-reproduce, generating new particles at the expenses of a suitable precursor. Recently, similar studies are in progress on more complex vesicle-based systems, namely semi-synthetic minimal cells. These are artificial cell-like compartments that are built by filling liposomes with the minimal number of biomolecules, such as DNA, ribosomes, enzymes, etc., in order to construct a living cell in the laboratory. This approach aims to investigate the minimal requirements for molecular systems in order to display some living properties, while it finds relevance in origins of life studies and in synthetic (constructive) biology.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A vesicle bioreactor as a step toward an artificial cell assembly
Noireaux, V., & Libchaber, A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408236101 · Cited by 1,152
Template-directed synthesis of a genetic polymer in a model protocell
Mansy, S. S., Schrum, J. P., Krishnamurthy, M., Tobé, S., Treco, D. A., & Szostak, J. W. (2008) · Nature · doi:10.1038/nature07018 · Cited by 684
Coupled Growth and Division of Model Protocell Membranes
Zhu, T. F., & Szostak, J. W. (2009) · Journal of the American Chemical Society · doi:10.1021/ja900919c · Cited by 496
Autocatalytic self-replicating micelles as models for prebiotic structures
Bachmann, P. A., Luisi, P. L., & Lang, J. (1992) · Nature · doi:10.1038/357057a0 · Cited by 494
Self-citationLipid synthesis under hydrothermal conditions by Fischer-Tropsch-type reactions
McCollom, T. M., Ritter, G., & Simoneit, B. R. T. (1999) · Origins of life and evolution of the biosphere · doi:10.1023/a:1006592502746 · Cited by 475
Ufasomes are stable particles surrounded by unsaturated fatty acid membranes
GEBICKI, J. M., & HICKS, M. (1973) · Nature · doi:10.1038/243232a0 · Cited by 358
pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids.
Kamp, F., & Hamilton, J. A. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.23.11367 · Cited by 299
Lipid vesicles as possible intermediates in the origin of life
Luisi, P. L., Walde, P., & Oberholzer, T. (1999) · Current Opinion in Colloid & Interface Science · doi:10.1016/s1359-0294(99)00012-6 · Cited by 287
Self-citationLipid formation by aqueous Fischer-Tropsch-type synthesis over a temperature range of 100 to 400 °C
Rushdi, A. I., & Simoneit, B. R. T. (2001) · Origins of life and evolution of the biosphere · doi:10.1023/a:1006702503954 · Cited by 274
Boundary structures are formed by organic-components of the Murchison carbonaceous chondrite
Deamer, D. W. (1985) · Nature · doi:10.1038/317792a0 · Cited by 270
A kinetic study of the growth of fatty acid vesicles
Chen, I. A., & Szostak, J. W. (2004) · Biophysical Journal · doi:10.1529/biophysj.104.039875 · Cited by 251
Expression of a cascading genetic network within liposomes
Ishikawa, K., Sato, K., Shima, Y., Urabe, I., & Yomo, T. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.09.046 · Cited by 215
Production of RNA by a polymerase protein encapsulated within phospholipid vesicles
Chakrabarti, A. C., Breaker, R. R., Joyce, G. F., & Deamer, D. W. (1994) · Journal of Molecular Evolution · doi:10.1007/bf00160400 · Cited by 196
Toward the engineering of minimal living cells
Luisi, P. L. (2002) · The Anatomical Record · doi:10.1002/ar.10155 · Cited by 175
Self-citationSelf-replicating micelles — a chemical version of a minimal autopoietic system
Luisi, P. L., & Varela, F. J. (1989) · Origins of life and evolution of the biosphere · doi:10.1007/bf01808123 · Cited by 154
Self-citationMatrix effect in the size distribution of fatty acid vesicles
Blöchliger, E., Blocher, M., Walde, P., & Luisi, P. L. (1998) · The Journal of Physical Chemistry B · doi:10.1021/jp981234w · Cited by 152
Self-citationSelf-replicating reverse micelles and chemical autopoiesis
Bachmann, P. A., Walde, P., Luisi, P. L., & Lang, J. (1990) · Journal of the American Chemical Society · doi:10.1021/ja00178a073 · Cited by 143
Self-citationSurfactant Assemblies and their Various Possible Roles for the Origin(S) of Life
Walde, P. (2006) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-005-9004-3 · Cited by 138
Maurer, S. E., Deamer, D. W., Boncella, J. M., & Monnard, P.-A. (2009) · Astrobiology · doi:10.1089/ast.2009.0384 · Cited by 121
Stability of model membranes in extreme environments
Namani, T., & Deamer, D. W. (2008) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-008-9131-8 · Cited by 97
Evolution and self-assembly of protocells
Solé, R. V. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.10.004 · Cited by 59
Insights into the self-reproduction of oleate vesicles
Stano, P., Wehrli, E., & Luisi, P. L. (2006) · Journal of Physics: Condensed Matter · doi:10.1088/0953-8984/18/33/s37 · Cited by 54
Self-citationProtocell self-reproduction in a spatially extended metabolism–vesicle system
Macía, J., & Solé, R. V. (2007) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2006.10.021 · Cited by 29
Cited by
Supramolecular systems chemistry
Mattia, E., & Otto, S. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2014.337 · Cited by 1,018
Prebiotic Systems Chemistry: New Perspectives for the Origins of Life
Ruiz-Mirazo, K., Briones, C., & de la Escosura, A. (2014) · Chemical Reviews · doi:10.1021/cr2004844 · Cited by 930
Enzymatic reactions in confined environments
Küchler, A., Yoshimoto, M., Luginbühl, S., Mavelli, F., & Walde, P. (2016) · Nature Nanotechnology · doi:10.1038/nnano.2016.54 · Cited by 733
Kurihara, K., Tamura, M., Shohda, K.-I., Toyota, T., Suzuki, K., & Sugawara, T. (2011) · Nature Chemistry · doi:10.1038/nchem.1127 · Cited by 559
Bissette, A. J., & Fletcher, S. P. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201303822 · Cited by 403
Metadata
- Authors
- Stano, P., & Luisi, P. L.
- Venue
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 46
- Issue
- 21
- Pages
- 3639
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W2020417127
- Cited by
- 219
- References
- 23
- FWCI
- 12.76
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
