Lipid vesicles as possible intermediates in the origin of life
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The best, easily available embodiment for a single-phase multiple-function scenario is lipid phases.
“It appears that the best, easily available, embodiment for a single-phase multiple-function scenario is lipid phases [155].”
From Systems protobiology: origin of life in lipid catalytic networks (2018) · cites this paper as [155]
Lipid bilayer chemistry includes spontaneous accretion of diverse and potentially interacting molecules from dilute solutions and facilitation of mutual interactions due to proximity effects and reduced dimensionality.
“These features include spontaneous accretion of diverse and potentially interacting molecules from dilute solutions, and the facilitation of mutual interactions due to proximity effects and reduced dimensionality, as copiously indicated [29,67,115,154–156].”
From Systems protobiology: origin of life in lipid catalytic networks (2018) · cites this paper as [155]
The selection mechanism is especially high for peptides formed from racemic amino acids under hydrothermal conditions, and the selection effect may be stronger for peptides that are amphiphilic and reflect the spatial distribution of hydrophilicity and hydrophobicity of the bilayer membrane.
“The potential of this selection mechanism is especially high in the case of peptides which are being formed from racemic amino acids under hydrothermal conditions [24]. The selectivity for hydrophobic peptides has already gained early recognition [22]. However, the selection effect may even be stronger for those peptides which, with a suitable composition and sequence of amino acids, are amphiph”
From Selection of Prebiotic Molecules in Amphiphilic Environments (2017) · cites this paper as [22]
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- Authors
- Luisi, P. L., Walde, P., & Oberholzer, T.
- Affiliations
- ETH Zurich (CH)
- ORCID
- Walde, Peter
- Venue
- Current Opinion in Colloid & Interface Science
- Publisher
- Elsevier BV
- Published
- 1999-02
- Volume
- 4
- Issue
- 1
- Pages
- 33-39
- ISSN
- 1359-0294 (ISSN-L)
- OpenAlex
- W1985820082
- Cited by
- 287
- References
- 78
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 13 · 2023: 12 · 2022: 7 · 2021: 12 · 2020: 11 · 2019: 28 · 2018: 14 · 2017: 15 · 2016: 10 · 2015: 11 · 2014: 16 · 2013: 8 · 2012: 14
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Colloid & Interface Science (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Lipid Membrane Structure and Behavior
- Keywords
- lipid vesicles, liposomes, origin of life, prebiotic evolution, precursor cells, spontaneous vesicle formation, lipid bilayers, molecular complexity
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