New Methods of Drug Delivery
Abstract
Conventional forms of drug administration generally rely on pills, eye drops, ointments, and intravenous solutions. Recently, a number of novel drug delivery approaches have been developed. These approaches include drug modification by chemical means, drug entrapment in small vesicles that are injected into the bloodstream, and drug entrapment within pumps or polymeric materials that are placed in desired bodily compartments (for example, the eye or beneath the skin). These techniques have already led to delivery systems that improve human health, and continued research may revolutionize the way many drugs are delivered.
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The rate of drug release can be governed through polymer modification, the development of new polymers, or the synthesis of copolymers.
“The rate of release can be governed through polymer modification, the development of new polymers, or the synthesis of copolymers.233–235”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [233]
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- Authors
- Langer, R.
- Affiliations
- Department of Chemical Engineering, Harvard-MIT Division of Health Sciences and Technology, and Whitaker College of Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, and Department of Surgery, Children's Hospital, Boston, MA 02115.
- Venue
- Science
- Published
- 1990-09-28
- Volume
- 249
- Issue
- 4976
- Pages
- 1527-1533
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2162294498
- Cited by
- 1,778
- References
- 96
- Citations by year
- 2026: 18 · 2025: 45 · 2024: 36 · 2023: 54 · 2022: 69 · 2021: 62 · 2020: 67 · 2019: 49 · 2018: 63 · 2017: 43 · 2016: 65 · 2015: 58 · 2014: 66 · 2013: 73 · 2012: 64
- FWCI
- 7.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of General Medical Sciences (R01GM026698, GM 26698)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Keywords
- drug delivery systems, drug modification, liposomes, polymeric drug delivery, implantable drug pumps, ocular drug delivery, transdermal drug delivery, controlled drug release
- MeSH terms
- Administration, Cutaneous, Delayed-Action Preparations, Dosage Forms, Drug Carriers, Humans, Liposomes, Peptides, Proteins
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