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Making carbon nanotubes biocompatible and biodegradable
Open accessAbstract
Carbon nanotubes are promising nanomaterials with great potential in the field of nanomedicine for both therapeutic and diagnostic applications. Different approaches have been developed to render this material biocompatible and to modulate any ensuing toxic effects. In the context of medical use, although chemically functionalised carbon nanotubes display reduced toxicity, they are still considered with scepticism due to their perceived non-biodegradability. Recently, it has been demonstrated that functionalised carbon nanotubes can be degraded by oxidative enzymes. This finding is offering a new perspective for the development of carbon nanotubes in medicine. This article highlights recent advances that can act as paradigm-shifts towards the design of biocompatible and biodegradable functionalised carbon nanotubes and allow their translation into the clinic.
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Cited by
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Herbert, R., Kim, J.-H., Kim, Y., Lee, H., & Yeo, W.-H. (2018) · Materials · doi:10.3390/ma11020187 · Cited by 220
Modified poly(3-hydroxybutyrate)-based scaffolds in tissue engineering applications: A review
Soleymani Eil Bakhtiari, S., Karbasi, S., & Toloue, E. B. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.10.255 · Cited by 100
Kuempel, E. D., Jaurand, M.-C., Møller, P., Morimoto, Y., Kobayashi, N., Pinkerton, K. E., Sargent, L. M., Vermeulen, R. C. H., Fubini, B., & Kane, A. B. (2017) · Critical Reviews in Toxicology · doi:10.1080/10408444.2016.1206061 · Cited by 89
Dong, P.-X., Wan, B., Wang, Z.-X., Guo, L.-H., Yang, Y., & Zhao, L. (2013) · Nanotoxicology · doi:10.3109/17435390.2012.694487 · Cited by 42
Metadata
- Authors
- Bianco, A., Kostarelos, K., & Prato, M.
- Venue
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2011
- Volume
- 47
- Issue
- 37
- Pages
- 10182
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W1975408440
- Cited by
- 384
- References
- 0
- FWCI
- 17.50
- Type
- journal article
- Language
- en
- Open access
- green
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