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Cited by 572

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Thermophysical and biological responses of gold nanoparticle laser heating

Qin, Zhenpeng, Bischof, John C.·2012·Chem. Soc. Rev.

Abstract

A compelling vision in nanomedicine is the use of self directed nanoparticles that can accumulate in areas of disease to perform designed functions, such as molecular delivery or destruction, endosomal release of genes or siRNA, and selective cell or tumor destruction with nano to macroscale spatiotemporal control and precision. These functions are increasingly achieved by gold nanoparticles (GNPs, such as sphere, shell or rod) that can be activated with a laser "switch". A defining aspect of this "switch" is GNP absorption of laser light and the ensuing heat generation and temperature change that can be confined or propagated through multiple scales from the nanoparticle surface up through bulk biological cells and tissues. In this critical review, we discuss the fundamental mechanisms of laser GNP heat generation, the measurement and modelling of the ensuing thermal response, and a number of the evolving biological applications dependent on this new technology (181 references).

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Crossref · 10.1039/c1cs15184c

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Metadata

Authors
Qin, Z., & Bischof, J. C.
Venue
Chem. Soc. Rev.
Published
2012
Volume
41
Issue
3
Pages
1191-1217
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
OpenAlex
W2120908183
Cited by
572
References
5
FWCI
0.53
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.