The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Physical basis and biological mechanisms of gold nanoparticle radiosensitization
Abstract
The unique properties of nanomaterials, in particular gold nanoparticles (GNPs) have applications for a wide range of biomedical applications. GNPs have been proposed as novel radiosensitizing agents due to their strong photoelectric absorption coefficient. Experimental evidence supporting the application of GNPs as radiosensitizing agents has been provided from extensive in vitro investigation and a relatively limited number of in vivo studies. Whilst these studies provide experimental evidence for the use of GNPs in combination with ionising radiation, there is an apparent disparity between the observed experimental findings and the level of radiosensitization predicted by mass energy absorption and GNP concentration. This review summarises experimental findings and attempts to highlight potential underlying biological mechanisms of response in GNP radiosensitization.
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Cited by
Gold nanoparticles for cancer radiotherapy: a review
Haume, K., Rosa, S., Grellet, S., Śmiałek, M. A., Butterworth, K. T., Solov’yov, A. V., Prise, K. M., Golding, J., & Mason, N. J. (2016) · Cancer Nanotechnology · doi:10.1186/s12645-016-0021-x · Cited by 445
Self-citationGold Nanoparticles as Radiosensitizers in Cancer Radiotherapy
Chen, Y., Yang, J., Fu, S., & Wu, J. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s272902 · Cited by 319
Cui, L., Her, S., Dunne, M., Borst, G. R., De Souza, R., Bristow, R. G., Jaffray, D. A., & Allen, C. (2017) · Radiation Research · doi:10.1667/rr14578.1 · Cited by 58
Choi, B. J., Jung, K. O., Graves, E. E., & Pratx, G. (2018) · Nanotechnology · doi:10.1088/1361-6528/aae272 · Cited by 57
Kefayat, A., Ghahremani, F., Motaghi, H., & Mehrgardi, M. A. (2019) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2019.01.037 · Cited by 54
Metadata
- Authors
- Butterworth, K. T., McMahon, S. J., Currell, F. J., & Prise, K. M.
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2012
- Volume
- 4
- Issue
- 16
- Pages
- 4830
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- OpenAlex
- W2132317474
- Cited by
- 478
- References
- 45
- FWCI
- 15.65
- Type
- journal article
- Language
- en
- Open access
- closed
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- Butterworth, K. T., McMahon, S. J., Currell, F. J., & Prise, K. M. (2012). Physical basis and biological mechanisms of gold nanoparticle radiosensitization. Nanoscale. https://doi.org/10.1039/c2nr31227a
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
