Zwitteration of dextran: A facile route to integrate antifouling, switchability and optical transparency into natural polymers
Abstract
This communication reports a facile method for zwitteration of dextran with carboxybetaine (CB), which integrates superior antifouling properties, switchability between zwitterionic and cationic forms, as well as enhanced optical transparency into one polysaccharide material. This study provides a new avenue for generating multifunctional zwitterionic CB materials in situ.
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Dextran as a shielding agent for nanoparticles displayed anti-fouling effects and prolonged circulation in animal models.
“Interestingly, some studies revealed that dextran as a shielding agent for nanoparticles displayed anti-fouling effects and prolonged circulation in animal models [96, 97].”
From Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval. (2020) · cites this paper as [97]
Dextran has been indicated as a shielding agent for nanoparticles and prolonged circulation in vivo.
“Importantly, some reports indicated dextran as a shielding agent for nanoparticles and prolonged circulation in vivo [66].”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [66]
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- Authors
- Cao, B., Li, L., Wu, H., Tang, Q., Sun, B., Dong, H., Zhe, J., & Cheng, G.
- Affiliations
- University of Akron (US)
- University of California, Los Angeles (US)
- Clarkson University (US)
- Corresponding author
- Cheng, Gang
- Venue
- Chem. Commun.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2014
- Volume
- 50
- Issue
- 24
- Pages
- 3234-3237
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W2110637536
- Cited by
- 66
- References
- 29
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 11 · 2019: 7 · 2018: 9 · 2017: 8 · 2016: 8 · 2015: 6 · 2014: 8
- FWCI
- 3.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Communications (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
- Physical Sciences › Engineering › Ocean Engineering › Marine Biology and Environmental Chemistry
- Keywords
- dextran, carboxybetaine, zwitterionic polymers, antifouling, switchable materials, optical transparency, polysaccharide modification, cationic form
- MeSH terms
- Polysaccharides, Molecular Structure, Optical Phenomena, Biofouling
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