The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes
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Native mass spectrometry can provide insight into the structure of macromolecular biological systems.
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“More recently, instrument hardware improvements have led to enhanced large ion transmission and detection, especially with the implementation of ultra-high mass range (UHMR) Orbitraps that are capable of analyzing species at 70,000 m/z and mass as large as 800 kDa [103,104].”
From Top-down proteomics: challenges, innovations, and applications in basic and clinical research (2020) · cites this paper as [103]
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Citations
Cites
Electrospray Ionization for Mass Spectrometry of Large Biomolecules
Fenn, J. B., Mann, M., Meng, C. K., Wong, S. F., & Whitehouse, C. M. (1989) · Science · doi:10.1126/science.2675315 · Cited by 7,634
Analytical Properties of the Nanoelectrospray Ion Source
Wilm, M. S., & Mann, M. (1996) · Analytical Chemistry · doi:10.1021/ac9509519 · Cited by 1,866
Studying noncovalent protein complexes by electrospray ionization mass spectrometry
Loo, J. A. (1997) · Mass Spectrometry Reviews · doi:10.1002/(sici)1098-2787(1997)16:1 · Cited by 1,152
Ion mobility–mass spectrometry analysis of large protein complexes
Ruotolo, B. T., Benesch, J. L. P., Sandercock, A. M., Hyung, S., & Robinson, C. V. (2008) · Nature Protocols · doi:10.1038/nprot.2008.78 · Cited by 1,095
Electrospray and Taylor-Cone theory, Dole's beam of macromolecules at last?
Wilm, M. S., & Mann, M. (1994) · International Journal of Mass Spectrometry and Ion Processes · doi:10.1016/0168-1176(94)04024-9 · Cited by 976
Native mass spectrometry: a bridge between interactomics and structural biology
Heck, A. J. R. (2008) · Nature Methods · doi:10.1038/nmeth.1265 · Cited by 766
Self-citationDetermining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry
Hernández, H., & Robinson, C. V. (2007) · Nature Protocols · doi:10.1038/nprot.2007.73 · Cited by 663
Katta, V., & Chait, B. T. (1991) · Journal of the American Chemical Society · doi:10.1021/ja00022a058 · Cited by 476
High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies
Rose, R. J., Damoc, E., Denisov, E., Makarov, A., & Heck, A. J. R. (2012) · Nature Methods · doi:10.1038/nmeth.2208 · Cited by 392
Self-citationShibuta, Y., Sakane, S., Miyoshi, E., Okita, S., Takaki, T., & Ohno, M. (2017) · Nature Communications · doi:10.1038/s41467-017-00017-5 · Cited by 296
Interrogating viral capsid assembly with ion mobility–mass spectrometry
Uetrecht, C., Barbu, I. M., Shoemaker, G. K., van Duijn, E., & Heck, A. J. R. (2011) · Nature Chemistry · doi:10.1038/nchem.947 · Cited by 267
Self-citationStudying 18 MDa Virus Assemblies with Native Mass Spectrometry
Snijder, J., Rose, R., Veesler, D., Johnson, J. E., & Heck, A. J. R. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201210197 · Cited by 191
Self-citationSnijder, J., van de Waterbeemd, M., Damoc, E., Denisov, E., Grinfeld, D., Bennett, A., Agbandje-McKenna, M., Makarov, A., & Heck, A. J. R. (2014) · Journal of the American Chemical Society · doi:10.1021/ja502616y · Cited by 168
Self-citationHigh-fidelity mass analysis unveils heterogeneity in intact ribosomal particles
van de Waterbeemd, M., Fort, K. L., Boll, D., Reinhardt-Szyba, M., Routh, A., Makarov, A., & Heck, A. J. R. (2017) · Nature Methods · doi:10.1038/nmeth.4147 · Cited by 168
Self-citationAnalytical Approaches for Size and Mass Analysis of Large Protein Assemblies
Snijder, J., & Heck, A. J. R. (2014) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-071213-020015 · Cited by 71
Self-citationTriple-Stage Mass Spectrometry Unravels the Heterogeneity of an Endogenous Protein Complex
Ben-Nissan, G., Belov, M. E., Morgenstern, D., Levin, Y., Dym, O., Arkind, G., Lipson, C., Makarov, A. A., & Sharon, M. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b00518 · Cited by 54
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High-Resolution Native Mass Spectrometry
Tamara, S., den Boer, M. A., & Heck, A. J. R. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00212 · Cited by 511
Self-citationAdeno-associated virus capsid assembly is divergent and stochastic
Wörner, T. P., Bennett, A. D., Habka, S., Snijder, J., Friese, O. V., Powers, T. W., Agbandje‐McKenna, M., & Heck, A. J. R. (2021) · Nature Communications · doi:10.1038/s41467-021-21935-5 · Cited by 228
Self-citationWörner, T. P., Snijder, J., Bennett, A., Agbandje-McKenna, M., Makarov, A. A., & Heck, A. J. R. (2020) · Nature Methods · doi:10.1038/s41592-020-0770-7 · Cited by 186
Self-citationProtein–Small Molecule Interactions in Native Mass Spectrometry
Bennett, J. L., Nguyen, G. T. H., & Donald, W. A. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00293 · Cited by 161
Top-down proteomics: challenges, innovations, and applications in basic and clinical research
Brown, K. A., Melby, J. A., Roberts, D. S., & Ge, Y. (2020) · Expert Review of Proteomics · doi:10.1080/14789450.2020.1855982 · Cited by 152
Metadata
- Authors
- Fort, K. L., van de Waterbeemd, M., Boll, D., Reinhardt-Szyba, M., Belov, M. E., Sasaki, E., Zschoche, R., Hilvert, D., Makarov, A. A., & Heck, A. J. R.
- Affiliations
- Utrecht University (NL)
- Biomolecular Mass Spectrometry and Proteomics
- Thermo Fisher Scientific (Germany) (DE)
- ETH Zurich (CH)
- Corresponding author
- Heck, Albert J. R.
- Venue
- The Analyst
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2018
- Volume
- 143
- Issue
- 1
- Pages
- 100-105
- ISSN
- 0003-2654 (ISSN-L)
- 1364-5528
- OpenAlex
- W2767559908
- Cited by
- 122
- References
- 16
- Citations by year
- 2026: 10 · 2025: 11 · 2024: 11 · 2023: 12 · 2022: 13 · 2021: 20 · 2020: 18 · 2019: 18 · 2018: 8
- FWCI
- 5.93
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Analyst (publishedVersion)
- PubMed (publishedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, other-oa)
- Utrecht University Repository (Utrecht University) (submittedVersion)
- Funders
- Stichting voor Fundamenteel Onderzoek der Materie (12PR3303-2)
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek (184.032.201, 718.015.003)
- H2020 Future and Emerging Technologies (686547)
- Topics
- Physical Sciences › Chemistry › Spectroscopy › Mass Spectrometry Techniques and Applications
- Physical Sciences › Chemistry › Spectroscopy › Advanced Proteomics Techniques and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
- Keywords
- native mass spectrometry, macromolecular complexes, signal intensity enhancement, mass resolution
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