Heck, Albert J. R.

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

Mellacheruvu, D., Wright, Z., Couzens, A. L., Lambert, J.-P., St-Denis, N. A., Li, T., Miteva, Y. V., Hauri, S., Sardiu, M. E., Low, T. Y., et al. (2013) · Nature Methods

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 1,686

Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex

Li, V. S. W., Ng, S. S., Boersema, P. J., Low, T. Y., Karthaus, W. R., Gerlach, J. P., Mohammed, S., Heck, A. J. R., Maurice, M. M., Mahmoudi, T., et al. (2012) · Cell

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

Cited by 889

Native mass spectrometry: a bridge between interactomics and structural biology

Heck, A. J. R. (2008) · Nature Methods

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 766

Identification of CMTM6 and CMTM4 as PD-L1 protein regulators

Mezzadra, R., Sun, C., Jae, L. T., Gomez-Eerland, R., de Vries, E., Wu, W., Logtenberg, M. E. W., Slagter, M., Rozeman, E. A., Hofland, I., et al. (2017) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 697

Native Mass Spectrometry: What is in the Name?

Leney, A. C., & Heck, A. J. R. (2017) · Journal of the American Society for Mass Spectrometry

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 602

High-Resolution Native Mass Spectrometry

Tamara, S., den Boer, M. A., & Heck, A. J. R. (2022) · Chemical Reviews

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 511

NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling

Dondelinger, Y., Jouan-Lanhouet, S., Divert, T., Theatre, E., Bertin, J., Gough, P. J., Giansanti, P., Heck, A. J. R., Dejardin, E., Vandenabeele, P., et al. (2015) · Molecular Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 431

High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies

Rose, R. J., Damoc, E., Denisov, E., Makarov, A., & Heck, A. J. R. (2012) · Nature Methods

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 392

Interrogating viral capsid assembly with ion mobility–mass spectrometry

Uetrecht, C., Barbu, I. M., Shoemaker, G. K., van Duijn, E., & Heck, A. J. R. (2011) · Nature Chemistry

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 267

The diverse and expanding role of mass spectrometry in structural and molecular biology

Lössl, P., van de Waterbeemd, M., & Heck, A. J. (2016) · The EMBO Journal

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 222

Triplex protein quantification based on stable isotope labeling by peptide dimethylation applied to cell and tissue lysates

Boersema, P. J., Aye, T. T., van Veen, T. A. B., Heck, A. J. R., & Mohammed, S. (2008) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 220

Resolving heterogeneous macromolecular assemblies by Orbitrap-based single-particle charge detection mass spectrometry

Wörner, T. P., Snijder, J., Bennett, A., Agbandje-McKenna, M., Makarov, A. A., & Heck, A. J. R. (2020) · Nature Methods

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 186

Defining the Stoichiometry and Cargo Load of Viral and Bacterial Nanoparticles by Orbitrap Mass Spectrometry

Snijder, J., van de Waterbeemd, M., Damoc, E., Denisov, E., Grinfeld, D., Bennett, A., Agbandje-McKenna, M., Makarov, A., & Heck, A. J. R. (2014) · Journal of the American Chemical Society

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 168

High-fidelity mass analysis unveils heterogeneity in intact ribosomal particles

van de Waterbeemd, M., Fort, K. L., Boll, D., Reinhardt-Szyba, M., Routh, A., Makarov, A., & Heck, A. J. R. (2017) · Nature Methods

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 168

Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity

Yang, Y., Liu, F., Franc, V., Halim, L. A., Schellekens, H., & Heck, A. J. R. (2016) · Nature Communications

Glycosylation and Glycoproteins ResearchMass Spectrometry Techniques and Applications

Cited by 152

Quantitative Proteomics by Metabolic Labeling of Model Organisms

Gouw, J. W., Krijgsveld, J., & Heck, A. J. R. (2010) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 151

Norwalk Virus Assembly and Stability Monitored by Mass Spectrometry

Shoemaker, G. K., van Duijn, E., Crawford, S. E., Uetrecht, C., Baclayon, M., Roos, W. H., Wuite, G. J. L., Estes, M. K., Prasad, B. V. V., & Heck, A. J. R. (2010) · Molecular & Cellular Proteomics

Mass Spectrometry Techniques and ApplicationsViral gastroenteritis research and epidemiology

Cited by 140

Toward an Optimized Workflow for Middle-Down Proteomics

Cristobal, A., Marino, F., Post, H., van den Toorn, H. W. P., Mohammed, S., & Heck, A. J. R. (2017) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 130

Probing the biophysical interplay between a viral genome and its capsid

Snijder, J., Uetrecht, C., Rose, R. J., Sanchez-Eugenia, R., Marti, G. A., Agirre, J., Guérin, D. M. A., Wuite, G. J. L., Heck, A. J. R., & Roos, W. H. (2013) · Nature Chemistry

Mass Spectrometry Techniques and ApplicationsProtein Structure and Dynamics

Cited by 127

Glycoproteomics: A Balance between High-Throughput and In-Depth Analysis

Yang, Y., Franc, V., & Heck, A. J. R. (2017) · Trends in Biotechnology

Glycosylation and Glycoproteins ResearchAdvanced Proteomics Techniques and Applications

Cited by 122

Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes

Fort, K. L., van de Waterbeemd, M., Boll, D., Reinhardt-Szyba, M., Belov, M. E., Sasaki, E., Zschoche, R., Hilvert, D., Makarov, A. A., & Heck, A. J. R. (2018) · The Analyst

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 122

Protease bias in absolute protein quantitation

Peng, M., Taouatas, N., Cappadona, S., van Breukelen, B., Mohammed, S., Scholten, A., & Heck, A. J. R. (2012) · Nature Methods

Advanced Proteomics Techniques and ApplicationsUbiquitin and proteasome pathways

Cited by 90

Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes

Milenkovic, D., Misic, J., Hevler, J. F., Molinié, T., Chung, I., Atanassov, I., Li, X., Filograna, R., Mesaros, A., Mourier, A., et al. (2023) · Cell Metabolism

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 68

Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes

Milenkovic, D., Misic, J., Hevler, J. F., Molinié, T., Chung, I., Atanassov, I., Li, X., Filograna, R., Mesaros, A., Mourier, A., et al. (2023) · Cell Metabolism

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 68