Mucopenetrating micelles with a PEG corona

A standardised static in vitro digestion method suitable for food – an international consensus

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Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

Kim, H. J., Huh, D., Hamilton, G., & Ingber, D. E. (2012) · Lab on a Chip · doi:10.1039/c2lc40074j · Cited by 1,734

Barrier properties of mucus

Cone, R. A. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.09.008 · Cited by 1,459

Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus

Lai, S. K., O'Hanlon, D. E., Harrold, S., Man, S. T., Wang, Y.-Y., Cone, R., & Hanes, J. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608611104 · Cited by 1,050

Structure, function, self-assembly, and applications of bottlebrush copolymers

Verduzco, R., Li, X., Pesek, S. L., & Stein, G. E. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00329b · Cited by 689

Addressing the PEG Mucoadhesivity Paradox to Engineer Nanoparticles that “Slip” through the Human Mucus Barrier

Wang, Y., Lai, S. K., Suk, J. S., Pace, A., Cone, R. A., & Hanes, J. S. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200803526 · Cited by 605

Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs

Lu, Y., & Park, K. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.08.042 · Cited by 572

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo

Xu, Q., Ensign, L. M., Boylan, N. J., Schön, A., Gong, X., Yang, J.-C., Lamb, N. W., Cai, S., Yu, T., Freire, E., et al. (2015) · ACS Nano · doi:10.1021/acsnano.5b03876 · Cited by 568

Diffusion of Macromolecules and Virus-Like Particles in Human Cervical Mucus

Olmsted, S. S., Padgett, J. L., Yudin, A. I., Whaley, K. J., Moench, T. R., & Cone, R. A. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)75844-4 · Cited by 544

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

Grossen, P., Witzigmann, D., Sieber, S., & Huwyler, J. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.05.028 · Cited by 512

Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

Ghezzi, M., Pescina, S., Padula, C., Santi, P., Del Favero, E., Cantù, L., & Nicoli, S. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.02.031 · Cited by 1,135

Overcoming colloidal nanoparticle aggregation in biological milieu for cancer therapeutic delivery: Perspectives of materials and particle design

Lim, S. H., Wong, T. W., & Tay, W. X. (2024) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2024.103094 · Cited by 90

Catalase-Powered Nanobots for Overcoming the Mucus Barrier

Serra-Casablancas, M., Carlo, V. D., Esporrín‐Ubieto, D., Prado-Morales, C., Bakenecker, A. C., & Sánchez, S. (2024) · ACS Nano · doi:10.1021/acsnano.4c01760 · Cited by 63

Recent Advancements in Using Polymers for Intestinal Mucoadhesion and Mucopenetration

Taipaleenmäki, E., & Städler, B. (2020) · Macromolecular Bioscience · doi:10.1002/mabi.201900342 · Cited by 55

3D printing of nanocomposite pills through desktop vat photopolymerization (stereolithography) for drug delivery reasons

Sharma, P. K., Choudhury, D., Yadav, V. S., Murty, U. S., & Banerjee, S. (2022) · 3D Printing in Medicine · doi:10.1186/s41205-022-00130-2 · Cited by 49

Engineering micelles with hydrophilic-lipophilic balance to overcome intestinal barrier for oral therapeutic application

Liu, K., Zhao, P., Chen, Y., Zhang, Y., Jin, J., & Wan, T. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102369 · Cited by 2

Betaine-Based and Polyguanidine-Inserted Zwitterionic Micelle as a Promising Platform to Conquer the Intestinal Mucosal Barrier

Liu, K., Chen, Y., Yang, D., Cai, Y., Yang, Z., & Jin, J. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c07658 · Cited by 16

Mucopenetrating polymer – Lipid hybrid nanovesicles as subunits in alginate beads as an oral formulation

Taipaleenmäki, E., Christensen, G., Brodszkij, E., Mouritzen, S. A., Gal, N., Madsen, S., Hedemann, M. S., Knudsen, T. A., Jensen, H. M., Christiansen, S. L., et al. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.03.047 · Cited by 37

Galactosamine-modified PEG-PLA/TPGS micelles for the oral delivery of curcumin

Sun, S., Du, X., Fu, M., Khan, A. R., Ji, J., Liu, W., & Zhai, G. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120227 · Cited by 55

Natural Gastrointestinal Stable Pea Albumin Nanomicelles for Capsaicin Delivery and Their Effects for Enhanced Mucus Permeability at Small Intestine

Li, Y., Mao, M., Yuan, X., Zhao, J., Ma, L., Chen, F., Liao, X., Hu, X., & Ji, J. (2024) · Biomaterials Research · doi:10.34133/bmr.0065 · Cited by 17

Cellular mechanism of oral absorption of solidified polymer micelles

Abramov, E., Cassiola, F. M., Schwob, O., Karsch-Bluman, A., Shapero, M., Ellis, J. L., Luyindula, D., Adini, I., D’Amato, R. J., & Benny, O. (2015) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2015.07.008 · Cited by 20

Enhanced Oral Delivery of Paclitaxel Using Acetylcysteine Functionalized Chitosan-Vitamin E Succinate Nanomicelles Based on a Mucus Bioadhesion and Penetration Mechanism

Lian, H., Zhang, T., Sun, J., Liu, X., Ren, G., Kou, L., Zhang, Y., Han, X., Ding, W., Ai, X., et al. (2013) · Molecular Pharmaceutics · doi:10.1021/mp400282r · Cited by 82

Preparation and Evaluation of Poly(Ethylene Glycol)–Poly(Lactide) Micelles as Nanocarriers for Oral Delivery of Cyclosporine A

Zhang, Y., Li, X., Zhou, Y., Wang, X., Fan, Y., Huang, Y., & Liu, Y. (2010) · Nanoscale Research Letters · doi:10.1007/s11671-010-9583-4 · Cited by 50

Smart Supramolecular Core–Shell Aggregates with Mucin‐Triggered Surface Switch for Effectively Overcoming Contradictory Mucus and Epithelium Barriers

Xu, X., Zhang, R., Liu, Y., Liu, J., Li, D., Ye, T., & Wang, S. (2025) · Small · doi:10.1002/smll.202509532 · Cited by 2

Cover Feature: Mucopenetrating Zwitterionic Micelles (ChemNanoMat 5/2020)

Taipaleenmäki, E., Brodszkij, E., & Städler, B. (2020) · ChemNanoMat · doi:10.1002/cnma.202000205