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Augmenting adaptive immunity: progress and challenges in the quantitative engineering and analysis of adaptive immune receptor repertoires
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The adaptive immune system is a natural diagnostic sensor and therapeutic.
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“Discerning the biases of antibody repertoires can provide insights into the natural diversity of the immune system [25].”
From Computational approaches to therapeutic antibody design: established methods and emerging trends (2020) · cites this paper as [25]
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“Current bioinformatic analyses of NGS repertoires focus on large-scale decoding of the immune responses, with several potential applications for therapeutic design [22, 25, 214].”
From Computational approaches to therapeutic antibody design: established methods and emerging trends (2020) · cites this paper as [25]
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Contrasting effects of SARS-CoV-2 vaccination vs. infection on antibody and TCR repertoires
Braun, J., Hill, E. D., Contreras, E., Yasuda, M., Morgan, A., Ditelberg, S., Winter, E., Callahan, C. J., Mazzoni, G., Kirmaier, A., et al. (2026) · PLoS ONE · doi:10.1371/journal.pone.0343939 · Cited by 1
Metadata
- Authors
- Brown, A. J., Snapkov, I., Akbar, R., Pavlović, M., Miho, E., Sandve, G. K., & Greiff, V.
- Affiliations
- Department of Biomedical Research
- University of Oslo (NO)
- FHNW University of Applied Sciences and Arts Northwestern Switzerland (CH)
- Corresponding author
- Sandve, Geir K.
- Greiff, Victor
- ORCID
- Venue
- Molecular Systems Design & Engineering
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2019
- Volume
- 4
- Issue
- 4
- Pages
- 701-736
- ISSN
- 2058-9689 (ISSN-L)
- OpenAlex
- W2926687552
- Cited by
- 59
- References
- 414
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 11 · 2023: 7 · 2022: 10 · 2021: 10 · 2020: 11 · 2019: 3
- FWCI
- 2.99
- Type
- journal article
- Language
- en
- Open access
- green
- arxiv.org
- Locations
- Molecular Systems Design & Engineering (publishedVersion)
- arXiv (Cornell University) (submittedVersion)
- arXiv (Cornell University)
- Funders
- Stiftelsen Kristian Gerhard Jebsen
- Leona M. and Harry B. Helmsley Charitable Trust (2019PG-T1D011)
- Horizon 2020 (825821)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Artificial Immune Systems Applications
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › vaccines and immunoinformatics approaches
- Keywords
- adaptive immunity, immune receptor repertoire, T cell receptor, B cell receptor
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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