A new integrated method for tissue extracellular vesicle enrichment and proteome profiling
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Extracellular vesicles were successfully extracted from mouse liver tissue using kit combined with TiO 2 .
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A substantial quantity of EVs is needed to address CNS diseases, particularly in cases where the affected region is sizable.
“Furthermore, a substantial quantity of EVs is needed to address CNS diseases, particularly in cases where the affected region is sizable.”
From Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions (2024) · cites this paper as [330]
The Introduction discusses isolating EVs from solid tissues for tumor research, and the Results examine EVs from liver tissue in mice with hepatocellular carcinoma. Searches for CNS disease treatment, EV quantities, and affected-region size found no passage addressing the claimed need for a substantial quantity of EVs. (LLM, conf=0.75)
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- Authors
- Zhang, M., Liu, T., Du, Z., Li, H., & Qin, W.
- Affiliations
- Qingdao University (CN)
- Beijing Proteome Research Center (CN)
- Corresponding author
- Li, Hang
- Qin, Weijie
- Venue
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2022
- Volume
- 12
- Issue
- 51
- Pages
- 33409-33418
- ISSN
- 2046-2069 (ISSN-L)
- PMC
- PMC9679920
- OpenAlex
- W4310334978
- Cited by
- 10
- References
- 42
- Citations by year
- 2026: 4 · 2025: 1 · 2024: 3 · 2023: 2
- FWCI
- 0.49
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- RSC Advances (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (32088101, 22074158, 21904008)
- National Key Research and Development Program of China (2021YFA1302604, 2021YFA1301601)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Physical Sciences › Chemistry › Spectroscopy › Advanced Proteomics Techniques and Applications
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- extracellular vesicles, proteomic profiling, hepatocellular carcinoma, liver tissue, differentially expressed proteins, biomarker discovery, drug screening
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