Novel Poly-Deep Eutectic Solvent-Functionalized Magnetic Graphene Oxide Nanomaterials for High-Performance Solid-Phase Extraction of Trypsin
Abstract
Three novel polymethacrylic acid-based deep eutectic solvent (DES)-functionalized magnetic graphene oxide composites were designed and successfully synthesized via the radical polymerization method.
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Poly-DES-functionalized magnetic graphene oxide nanomaterials show excellent performance in the solid-phase extraction of trypsin.
“More recently, Chen et al. [112] developed poly-DES-functionalized magnetic graphene oxide nanomaterials and demonstrated their excellent performance in the solid-phase extraction of trypsin, highlighting the potential of polymeric DES coatings for efficient biomolecule enrichment.”
From Eco-Friendly Deep Eutectic Solvent-Based Extraction Technologies: A Comprehensive Review of Principles, Applications, and Comparative Insights (2026) · cites this paper as [112]
Polymeric DES coatings have potential for efficient biomolecule enrichment.
“highlighting the potential of polymeric DES coatings for efficient biomolecule enrichment.”
From Eco-Friendly Deep Eutectic Solvent-Based Extraction Technologies: A Comprehensive Review of Principles, Applications, and Comparative Insights (2026) · cites this paper as [112]
DES-coated magnetite materials simplify phase separation during magnetic solid-phase extraction.
“while DES-coated magnetite materials simplify phase separation during magnetic solid-phase extraction [112].”
From Eco-Friendly Deep Eutectic Solvent-Based Extraction Technologies: A Comprehensive Review of Principles, Applications, and Comparative Insights (2026) · cites this paper as [112]
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Alahmadi, S. M., & Abu-Dief, A. M. (2026) · Sustainable Chemistry · doi:10.3390/suschem7030033 · Cited by 1 · see citing works
“More recently, Chen et al. [112] developed poly-DES-functionalized magnetic graphene oxide nanomaterials and demonstrated their excellent performance in the solid-phase extraction of trypsin, highlighting the potential of polymeric DES coatings for efficient biomolecule enrichment.”
- Authors
- Chen, J., He, X., & Wang, Y.
- Affiliations
- Tongren University (CN)
- Hunan University (CN)
- Corresponding author
- Chen, Jing
- Wang, Yuzhi
- Venue
- Analytical Methods
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2025
- Volume
- 17
- Issue
- 16
- Pages
- 3132-3144
- ISSN
- 1759-9660 (ISSN-L)
- 1759-9679
- OpenAlex
- W4408685083
- Cited by
- 5
- References
- 35
- Citations by year
- 2026: 2 · 2025: 3
- FWCI
- 1.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Analytical Methods (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (22464015)
- Guizhou Provincial Science and Technology Department (QKHJC-ZK[2023]YB459)
- Topics
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Physical Sciences › Chemical Engineering › Catalysis › Ionic liquids properties and applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Enzyme Catalysis and Immobilization
- Keywords
- deep eutectic solvents, magnetic graphene oxide, poly(methacrylic acid), solid-phase extraction, trypsin, magnetic nanomaterials, radical polymerization, protein extraction
- MeSH terms
- Deep Eutectic Solvents, Animals, Cattle, Graphite, Polymethacrylic Acids, Trypsin, Nanostructures, Solid Phase Extraction
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