A multifunctional curcumin–Fe 3 O 4 @ZIF-8 nanoformulation as a T 2 MRI contrast agent and pH-responsive theranostic platform for targeted ROS generation, radiosensitization, and triple-negative breast cancer treatment
Abstract
, underscoring its radiosensitization capabilities. Cell cycle analysis revealed G2/M-phase arrest, contributing to impaired cancer cell proliferation. Apoptosis assays confirmed a significant increase in early and late apoptotic populations, while real-time PCR analysis showed significant downregulation of anti-apoptotic BCL-xL and cyclin D1 genes with considerable upregulation of pro-apoptotic BAX, thus reinforcing the mechanism of tumor suppression. This triple-action theranostic system surpasses conventional chemotherapy and standalone MRI contrast agents by combining precision imaging with targeted therapy, offering transformative advancement in TNBC treatment.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Microenvironment-responsive functionalization targeting hypoxia, pH, and redox conditions was reported in multiple studies.
“Microenvironment-responsive functionalization targeting hypoxia, pH, and redox conditions was reported in multiple studies [17,19,53,67].”
From Nanoparticle-Mediated Radiosensitization in Breast Cancer: A Systematic Review of Preclinical Evidence and Translational Challenges (2026) · cites this paper as [67]
Multimodal therapeutic approaches were described, combining radiotherapy with chemotherapy, photothermal therapy, photodynamic therapy, or immunomodulatory strategies.
“Multimodal therapeutic approaches were also described, combining radiotherapy with chemotherapy, photothermal therapy, photodynamic therapy, or immunomodulatory strategies [39,43,49,50,67,68,69].”
From Nanoparticle-Mediated Radiosensitization in Breast Cancer: A Systematic Review of Preclinical Evidence and Translational Challenges (2026) · cites this paper as [67]
In some studies, marked tumor regression or complete tumor responses were described in a subset of treated animals.
“In some studies, marked tumor regression or complete tumor responses were described in a subset of treated animals [13,17,62,67].”
From Nanoparticle-Mediated Radiosensitization in Breast Cancer: A Systematic Review of Preclinical Evidence and Translational Challenges (2026) · cites this paper as [67]
Cites
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
Morris, G. M., Huey, R., Lindstrom, W., Sanner, M. F., Belew, R. K., Goodsell, D. S., & Olson, A. J. (2009) · Journal of Computational Chemistry · doi:10.1002/jcc.21256 · Cited by 25,745 · see citing works
Current and future burden of breast cancer: Global statistics for 2020 and 2040
Arnold, M., Morgan, E., Rumgay, H., Mafra, A., Singh, D., Laversanne, M., Vignat, J., Gralow, J. R., Cardoso, F., Siesling, S., et al. (2022) · The Breast · doi:10.1016/j.breast.2022.08.010 · Cited by 3,411 · see citing works
Transport properties of two finite armchair graphene nanoribbons
Rosales, L., & González, J. W. (2013) · Nanoscale Research Letters · doi:10.1186/1556-276x-8-1 · Cited by 1,956 · see citing works
Exploring treatment options in cancer: tumor treatment strategies
Liu, B., Zhou, H., Tan, L., Siu, K. T. H., & Guan, X.-Y. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01856-7 · Cited by 1,201 · see citing works
Giordano, A., & Tommonaro, G. (2019) · Nutrients · doi:10.3390/nu11102376 · Cited by 1,029 · see citing works
Metal–Organic Framework Nanocarriers for Drug Delivery in Biomedical Applications
Sun, Y., Zheng, L., Yang, Y. P., Qian, X., Fu, T., Li, X., Yang, Z., He, Y., Cui, C., & Tan, W. (2020) · Nano-Micro Letters · doi:10.1007/s40820-020-00423-3 · Cited by 731 · see citing works
GSH‐Depleted PtCu 3 Nanocages for Chemodynamic‐ Enhanced Sonodynamic Cancer Therapy
Zhong, X., Wang, X., Cheng, L., Tang, Y., Zhan, G., Gong, F., Zhang, R., Hu, J., Liu, Z., & Yang, X. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201907954 · Cited by 541 · see citing works
Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity
Sæbø, I. P., Bjørås, M., Franzyk, H., Helgesen, E., & Booth, J. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032914 · Cited by 471 · see citing works
Critical Role of Zinc as Either an Antioxidant or a Prooxidant in Cellular Systems
Lee, S. R. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/9156285 · Cited by 458 · see citing works
Kaur, H., Mohanta, G. C., Gupta, V., Kukkar, D., & Tyagi, S. (2017) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2017.07.004 · Cited by 437 · see citing works
In vitro hemolysis: Guidance for the pharmaceutical scientist
Amin, K., & Dannenfelser, R. (2006) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.20627 · Cited by 399 · see citing works
Red blood cell hemolysis during processing
Sowemimo-Coker, S. O. (2002) · Transfusion Medicine Reviews · doi:10.1053/tmrv.2002.29404 · Cited by 385 · see citing works
STOHS, S. J., Chen, O., Ray, S. D., Ji, J., Bucci, L. R., & Preuss, H. G. (2020) · Molecules · doi:10.3390/molecules25061397 · Cited by 375 · see citing works
Synthesis of Nearly Monodisperse Iron Oxide and Oxyhydroxide Nanocrystals
Liang, X., Wang, X. L., Zhuang, J., Chen, Y., Wang, D., & Li, Y. (2006) · Advanced Functional Materials · doi:10.1002/adfm.200500884 · Cited by 353 · see citing works
Nanoparticles in cancer theragnostic and drug delivery: A comprehensive review
Al-Thani, A. N., Jan, A. G., Abbas, M. A. E., Geetha, M., & Sadasivuni, K. K. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122899 · Cited by 341 · see citing works
Israel, L. L., Galstyan, A., Holler, E., & Ljubimova, J. Y. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.01.009 · Cited by 337 · see citing works
Rahim, M. A., Jan, N., Khan, S., Shah, H., Madni, A., Khan, A., Jabar, A., Khan, S., Elhissi, A. M. A., Hussain, Z., et al. (2021) · Cancers · doi:10.3390/cancers13040670 · Cited by 330 · see citing works
Physicochemical Characterization and In Vitro Hemolysis Evaluation of Silver Nanoparticles
Choi, J. H., Reipa, V., Hitchins, V. M., Goering, P. L., & Malinauskas, R. A. (2011) · Toxicological Sciences · doi:10.1093/toxsci/kfr149 · Cited by 321 · see citing works
Santos-Martins, D., Forli, S., Ramos, M. J., & Olson, A. J. (2014) · Journal of Chemical Information and Modeling · doi:10.1021/ci500209e · Cited by 318 · see citing works
Zheng, M. J., Liu, S., Guan, X., & Xie, Z. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b04315 · Cited by 247 · see citing works
Vangijzegem, T., Lecomte, V., Ternad, I., Leuven, L. V., Müller, R. N., Stanicki, D., & Laurent, S. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15010236 · Cited by 230 · see citing works
Magnetic responsive Fe3O4-ZIF-8 core-shell composites for efficient removal of As(III) from water
Huo, J.-B., Xu, L., Yang, J. E., Cui, H., Yuan, B., & Fu, M. (2017) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2017.12.010 · Cited by 205 · see citing works
Maleki, A., Shahbazi, M., Alinezhad, V., & Santos, H. A. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.202000248 · Cited by 188 · see citing works
Self-citationTiwari, A., Singh, A. K., Garg, N., & Randhawa, J. K. (2017) · Scientific Reports · doi:10.1038/s41598-017-12786-6 · Cited by 187 · see citing works
Curcumin as a clinically-promising anti-cancer agent: pharmacokinetics and drug interactions
Adiwidjaja, J., McLachlan, A. J., & Boddy, A. V. (2017) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2017.1360279 · Cited by 173 · see citing works
Ferroptosis: a double-edged sword mediating immune tolerance of cancer
Dang, Q., Sun, Z., Wang, Y., Wang, L., Liu, Z., & Han, X. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05384-6 · Cited by 155 · see citing works
Ahmed, S. A., Bagchi, D., Katouah, H. A., Hasan, M. N., Altass, H. M., & Pal, S. K. (2019) · Scientific Reports · doi:10.1038/s41598-019-55542-8 · Cited by 151 · see citing works
Phytochemicals As Chemosensitizers: From Molecular Mechanism to Clinical Significance
Balachandran, V., Maliekal, T. T., & Anto, R. J. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4573 · Cited by 139 · see citing works
Zahmakıran, M. (2012) · Dalton Transactions · doi:10.1039/c2dt31779f · Cited by 133 · see citing works
Ayubi, M., Karimi, M. A., Abdpour, S., Rostamizadeh, K., Parsa, M., Zamani, M., & Saedi, A. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.109810 · Cited by 132 · see citing works
Importance of Iron Complexation for Fenton-Mediated Hydroxyl Radical Production at Circumneutral pH
Miller, C. J., Rose, A. L., & Waite, T. D. (2016) · Frontiers in Marine Science · doi:10.3389/fmars.2016.00134 · Cited by 121 · see citing works
Du, W., Gu, M., Hu, M., Pinchi, P., Chen, W., Ryan, M., Nold, T. M., Bannaga, A., & Xu, H. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109848 · Cited by 120 · see citing works
Yan, J., Liu, C., Wu, Q., Zhou, J., Xu, X., Zhang, L., Wang, D., Yang, F., & Zhang, H. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c02599 · Cited by 116 · see citing works
Singh, P. K., Wani, K. D., Kaul-Ghanekar, R., Prabhune, A. A., & Ogale, S. (2014) · RSC Advances · doi:10.1039/c4ra07300b · Cited by 116 · see citing works
Molla, A., Sahu, M., & Hussain, S. (2015) · Journal of Materials Chemistry A · doi:10.1039/c5ta02888d · Cited by 104 · see citing works
Verkhovskii, R. A., Aa, I., Ленгерт, Е. В., Tulyakova, K. A., Shilyagina, N. Y., & Ermakov, A. V. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15051566 · Cited by 102 · see citing works
Zinc-Based Metal-Organic Frameworks in Drug Delivery, Cell Imaging, and Sensing
Ali, R. S., Meng, H., & Li, Z. (2021) · Molecules · doi:10.3390/molecules27010100 · Cited by 101 · see citing works
Relaxivity of Ferumoxytol at 1.5 T and 3.0 T
Knobloch, G., Colgan, T. J., Wiens, C. N., Wang, X., Schubert, T. B., Hernando, D., Sharma, S. D., & Reeder, S. B. (2017) · Investigative Radiology · doi:10.1097/rli.0000000000000434 · Cited by 92 · see citing works
Metal–organic frameworks (MOFs): a novel support platform for ASNase immobilization
Ulu, A. (2020) · Journal of Materials Science · doi:10.1007/s10853-020-04452-6 · Cited by 86 · see citing works
Curcumin Regulates Cancer Progression: Focus on ncRNAs and Molecular Signaling Pathways
Wang, H., Zhang, K., Liu, J., Yang, J., Tian, Y., Chen, Y., Li, Y., Shao, M., Su, W., & Song, N. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.660712 · Cited by 84 · see citing works
Curcumin-Loaded ZIF-8 Nanomaterials: Exploring Drug Loading Efficiency and Biomedical Performance
Rahman, M. M., Kabir, M., Islam, T., Wang, Y., Meng, Q., Liu, H., Chen, S., & Wu, S. (2025) · ACS Omega · doi:10.1021/acsomega.4c09945 · Cited by 84 · see citing works
Lin, J., Xin, P., An, L., Xu, Y., Tao, C., Tian, Q., Zhou, Z., Hu, B. Q., & Yang, S. (2018) · Chemical Communications · doi:10.1039/c8cc08943d · Cited by 82 · see citing works
Recent Advances in Metal–Organic Frameworks for Applications in Magnetic Resonance Imaging
Bunzen, H., & Jirák, D. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c10272 · Cited by 82 · see citing works
Hosseini, S. R., Omidkhah, M., Lighvan, Z. M., Norouzbahari, S., & Ghadimi, A. (2022) · Separation and Purification Technology · doi:10.1016/j.seppur.2022.122679 · Cited by 77 · see citing works
Cycle arrest and apoptosis in MDA-MB-231/Her2 cells induced by curcumin
Sun, S.-H., Huang, H., Huang, C., & Lin, J.-K. (2012) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2012.05.036 · Cited by 74 · see citing works
Theranostic Fibers for Simultaneous Imaging and Drug Delivery
Jin, M., Yu, D., Geraldes, C. F. G. C., Williams, G. R., & Bligh, S. W. A. (2016) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.6b00197 · Cited by 73 · see citing works
Controlled synthesis of Fe 3 O 4 @ZIF-8 nanoparticles for drug delivery
Chen, G., Yu, B., Lu, C., Zhang, H., Shen, Y., & Cong, H. (2018) · CrystEngComm · doi:10.1039/c8ce01302k · Cited by 71 · see citing works
Rudolf, E., & Červinka, M. (2010) · BioMetals · doi:10.1007/s10534-010-9302-8 · Cited by 68 · see citing works
Cai, W., Zhang, W. Y., & Chen, Z. (2023) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2023.113170 · Cited by 61 · see citing works
Peng, S., Liu, X., Chen, Q., Yu, Y., Liu, M., & Zhang, X. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121358 · Cited by 58 · see citing works
Wei, Y., Liao, R., Mahmood, A. A., Xu, H., & Zhou, Q. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.03.046 · Cited by 56 · see citing works
Zeolitic imidazolate frameworks: From bactericidal properties to tissue regeneration
Kermanian, M., Nadri, S., Mohammadi, P., Iravani, S., Ahmadi, N., Alinezhad, V., Shokrgozar, M. A., Haddad, M., Mostafavi, E., & Maleki, A. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.06.002 · Cited by 55 · see citing works
Self-citationCao, S., Xu, H. Y., Lai, L.-H., Gu, W., Xu, P., Xiong, J., Yin, H., Li, X., Ma, Y., Zhou, J. W., et al. (2017) · Bioresources and Bioprocessing · doi:10.1186/s40643-017-0186-0 · Cited by 54 · see citing works
Pantwalawalkar, J. R., Mhettar, P., Nangare, S., Mali, R., Ghule, A. V., Patil, P. O., Mohite, S., More, H. N., & Jadhav, N. R. (2023) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.3c00507 · Cited by 54 · see citing works
Li, J., Hu, Z.-E., We, Y.-J., Liu, Y., Wang, N., & Yu, X. (2021) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2021.08.114 · Cited by 53 · see citing works
Advancements in the Application of the Fenton Reaction in the Cancer Microenvironment
Ou, R., Aodeng, G., & Ai, J. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15092337 · Cited by 52 · see citing works
Akhtar, H., Amara, U., Mahmood, K., Hanif, M., Khalid, M. A., Qadir, S., Peng, Q., Safdar, M., Amjad, M., Saif, M. Z., et al. (2024) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2024.103184 · Cited by 46 · see citing works
Doxorubicin-loaded Fe 3 O 4 -ZIF-8 nano-composites for hepatocellular carcinoma therapy
Cheng, C., Li, C., Zhu, X., Han, W., Li, J., & Lv, Y. (2019) · Journal of Biomaterials Applications · doi:10.1177/0885328219836540 · Cited by 43 · see citing works
Klein, S., Harreiß, C., Menter, C., Hümmer, J., Distel, L. V., Meyer, K., Hock, R., & Kryschi, C. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b03660 · Cited by 42 · see citing works
Radiosensitivity enhancement of Fe 3 O 4 @Ag nanoparticles on human glioblastoma cells
Zhang, X., Liu, Z., Lou, Z., Chen, F., Chang, S., Miao, Y., Zhou, Z. L., Hu, X., Feng, J., Ding, Q., et al. (2018) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2018.1439843 · Cited by 40 · see citing works
The Potential of Curcumin: A Multitargeting Agent in Cancer Cell Chemosensitization
Bordoloi, D., & Kunnumakkara, A. B. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812373-7.00002-4 · Cited by 35 · see citing works
Sheno, N. N., Farhadi, S., Maleki, A., & Hamidi, M. (2019) · New Journal of Chemistry · doi:10.1039/c8nj04715d · Cited by 35 · see citing works
Self-citationSekar, R., & Prabaharan, M. (2018) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2018.06.051 · Cited by 34 · see citing works
Enhancing X‐Ray Sensitization with Multifunctional Nanoparticles
Liu, J., Wu, J., Chen, T., Yang, B., Liu, X., Xi, J., Zhang, Z., Gao, Y., & Li, Z. (2024) · Small · doi:10.1002/smll.202400954 · Cited by 34 · see citing works
Wu, W., Yu, X., Sun, J., Han, Y., Ma, Y., Zhang, G., Ma, Q., Li, Q., & Xiang, H. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s438771 · Cited by 33 · see citing works
Zhang, Y., Huang, X., Wang, L., Cao, C., Zhang, H., Wei, P., Ding, H., Song, Y., Chen, Z., Qian, J., et al. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120720 · Cited by 31 · see citing works
An enhanced fluorescent ZIF-8 film by capturing guest molecules for light-emitting applications
Liu, Q., Tian, S., Zhao, X., & Sankar, G. (2021) · Journal of Materials Chemistry C · doi:10.1039/d1tc00457c · Cited by 29 · see citing works
Curcumin and Thymoquinone Combination Attenuates Breast Cancer Cell Lines’ Progression
Saddiq, A. A., El‐Far, A. H., Mohamed, S. A., Almaghrabi, O. A., & Mousa, S. A. (2022) · Integrative Cancer Therapies · doi:10.1177/15347354221099537 · Cited by 28 · see citing works
Yim, C., Lee, H., Lee, S.-H., & Jeon, S. (2017) · RSC Advances · doi:10.1039/c6ra25527b · Cited by 27 · see citing works
In Vitro Studies of Fe3O4‐ZIF‐8 Core–Shell Nanoparticles Designed as Potential Theragnostics
Ettlinger, R. L., Moreno, N., Ziółkowska, N., Ullrich, A., von Nidda, H. K., Jirák, D., Kerl, K., & Bunzen, H. (2020) · Particle & Particle Systems Characterization · doi:10.1002/ppsc.202000185 · Cited by 25 · see citing works
Bleul, R., Baki, A., Freese, C., Paysen, H., Kosch, O., & Wiekhorst, F. (2020) · Nanoscale Advances · doi:10.1039/d0na00343c · Cited by 24 · see citing works
Dietrich, H. (2013) · Journal of Emergency Nursing · doi:10.1016/j.jen.2012.11.002 · Cited by 23 · see citing works
Khalilian, S. F., Tohidi, M., & Rastegari, B. (2023) · ACS Omega · doi:10.1021/acsomega.2c06705 · Cited by 23 · see citing works
Liang, M., Zhou, W., Zhang, H., Zheng, J., Lin, J., An, L., & Yang, S. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb00068k · Cited by 21 · see citing works
Darroudi, M., Nazari, S. E., Asgharzadeh, F., Khalili‐Tanha, N., Khalili‐Tanha, G., Dehghani, T., Karimzadeh, M., Maftooh, M., Fern, G. A., Avan, A., et al. (2022) · Cancer Nanotechnology · doi:10.1186/s12645-022-00141-y · Cited by 20 · see citing works
Oulhakem, O., Guetni, I., Elansary, M., Belaiche, M., Mouhib, Y., Ferdi, C. A., Alaoui, K. B., & Lemine, O. M. (2023) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2023.171290 · Cited by 19 · see citing works
Xu, Z., Chu, F., Luo, X., Jiang, X., Cheng, L., Song, L., Hou, Y., & Hu, W. (2022) · ACS Applied Nano Materials · doi:10.1021/acsanm.1c04115 · Cited by 18 · see citing works
Scialla, S., Genicio, N., Brito, B., Wojciechowska, M. F. –., Stasiuk, G. J., Kruk, D., Bañobre‐López, M., & Gallo, J. (2022) · ACS Applied Nano Materials · doi:10.1021/acsanm.2c03537 · Cited by 18 · see citing works
Sergeeva, O. V., Luo, L., & Guiseppi‐Elie, A. (2025) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1499474 · Cited by 18 · see citing works
Arosio, P., Orsini, F., Brero, F., Mariani, M., Innocenti, C., Sangregorio, C., & Lascialfari, A. (2023) · Dalton Transactions · doi:10.1039/d2dt03387a · Cited by 17 · see citing works
Targeting Signaling Pathway by Curcumin in Osteosarcoma
Asemi, Z., Yousefi, B., Farnood, P. R., & Pazhooh, R. D. (2022) · Current Molecular Pharmacology · doi:10.2174/1874467215666220408104341 · Cited by 16 · see citing works
Kong, J., Xu, S., Dai, Y., Wang, Y., Zhao, Y., & Zhang, P. (2023) · ACS Omega · doi:10.1021/acsomega.3c04215 · Cited by 16 · see citing works
Effect of Ammonium Sulfide on Sulfidization Flotation of Malachite
Ibrahim, A. M., Jia, X., Su, C., Cai, J., Shen, P., & Liu, D. (2022) · Minerals · doi:10.3390/min12101193 · Cited by 14 · see citing works
Revolutionizing healthcare: inorganic medicinal nanoarchitectonics for advanced theranostics
Yu, S., Rejinold, N. S., Choi, G., & Choy, J. (2024) · Nanoscale Horizons · doi:10.1039/d4nh00497c · Cited by 14 · see citing works
Gokduman, K., & Gök, A. (2019) · Journal of Nanoscience and Nanotechnology · doi:10.1166/jnn.2020.17152 · Cited by 13 · see citing works
Ernst, M., Porȩba, T., Gnägi, L., & Gryn’ova, G. (2022) · The Journal of Physical Chemistry C · doi:10.1021/acs.jpcc.2c05561 · Cited by 13 · see citing works
Lourembam, R. M., Yadav, A. S., Kundu, G. C., & Mazumder, P. B. (2019) · Oriental Pharmacy and Experimental Medicine · doi:10.1007/s13596-019-00374-0 · Cited by 12 · see citing works
Klein, S., Otto, J., Harreiß, C., Distel, L. V., Leistner, A., Neuhuber, W., Spiecker, E., & Kryschi, C. (2021) · ACS Applied Bio Materials · doi:10.1021/acsabm.1c00803 · Cited by 11 · see citing works
Intravenous Catheters and Blood Samples
Phelan, M. P., Reineks, E. Z., & Kovach, A. (2016) · Journal of Emergency Nursing · doi:10.1016/j.jen.2015.10.012 · Cited by 7 · see citing works
Mai, T. T. T., Phan, K. S., Doan, B., Le, T. T. H., Thuy, U. T. D., Nguyen, Q. B. N., Tran, T. H. T., Trân, N. Q., Dang, L. H., & Ha, P. T. (2025) · RSC Advances · doi:10.1039/d5ra03379a · Cited by 5 · see citing works
Maschmeyer, R. T., Gholami, Y. H., & Kuncic, Z. (2020) · Physics in Medicine and Biology · doi:10.1088/1361-6560/ab8079 · Cited by 4 · see citing works
Curcumin modified Fe3O4 with efficient SDT for the treatment of breast cancer
Bai, X., Li, S., Yang, J., Lu, Y., Li, R., Song, J., & Guo, X. (2024) · Materials Letters · doi:10.1016/j.matlet.2024.137721 · Cited by 4 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Kohale, M., Inamdar, H., Kokate, K. K., Ingale, R. S., Joshi, J., Singh, D., Katti, A., Polshettiwar, S. A., Aher, R., & Kulkarni, S. S. (2026) · Progress in Crystal Growth and Characterization of Materials · doi:10.1016/j.pcrysgrow.2026.100698 · Cited by 20 · see citing works
Nguyen, L. M., Vu, G. T.-Q., Tran, M. H., Nguyen, T. M. H., Nguyen, T. P., Tran, D. L., Vong, L. B., & Nguyen, D. H. (2025) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2025.115867 · Cited by 9 · see citing works
Raju, P., Kannaiah, S., Sekar, N., Devi, W. S., & Mani, A. S. (2025) · Discover Chemistry. · doi:10.1007/s44371-025-00428-0 · Cited by 1 · see citing works
Malabanan, J. W. T., Nalinratana, N., Sorasitthiyanukarn, F. N., Jantaratana, P., Zhu, H., Vajragupta, O., Rojsitthisak, P., & Rojsitthisak, P. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.150227 · Cited by 1 · see citing works
Viswanathan, T. M., Siva, V., Padmavathi, K., Murugan, A., Shameem, A. S., Vasudevan, A., Al-Sehemi, A. G., Thangarasu, S., & Priya, B. S. R. (2026) · Journal of Nanotechnology · doi:10.1155/jnt/6618411 · Cited by 1 · see citing works
Lunca, S., Morarasu, S., & Dimofte, G. M. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27146522 · Cited by 2 · see citing works
Nanomaterial‐Enhanced Electrochemical Strategies for Sensitive and Selective Detection of Curcumin
Bahaabadi, Z. J., Karav, S., Kesharwani, P., & Sahebkar, A. (2026) · Electroanalysis · doi:10.1002/elan.70100
Curcumin as theranostics: imaging-guided therapeutics in oncology and neurodegenerative diseases
Yasir, M., Maurya, R. K., & Tripathi, A. S. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1790555
“Curcumin-Fe 3 O 4 @ZIF-8 nanoformulations serve as pH-responsive T 2 MRI contrast agents, exhibiting pH-dependent improvement in r 2 relaxivity values for theranostics in triple-negative breast cancer, integrating imaging, reactive oxygen species production, and radiosensitization (39).”
Magnetic Nanomedicine for Cancer: Mechanisms, Modalities, and Translation
Kadam, S., Sonavale, R. M., Das, R., Pawar, J., Shukla, N., Li, Z., Pathade, G. R., Kushwaha, N., Patel, A., Jadhav, S. A., et al. (2026) · Nano Select · doi:10.1002/nano.70190
Sheng, K., Zheng, X., Ren, J., Gao, Y., Long, J., Yu, Q., Deng, Z., 张学萍, Deng, W., Bao, T., et al. (2026) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2026.141803
- Authors
- Rahmani, A., Maleki, A., Jafari, R., Rezaeejam, H., & Nadri, S.
- Affiliations
- Zanjan University of Medical Sciences (IR)
- Corresponding author
- Nadri, Samad
- Venue
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2025
- Volume
- 13
- Issue
- 42
- Pages
- 13805-13829
- ISSN
- 2050-750X (ISSN-L)
- 2050-7518
- OpenAlex
- W4414886212
- Cited by
- 10
- References
- 92
- Citations by year
- 2026: 8 · 2025: 2
- FWCI
- 2.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Materials Chemistry B (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Zanjan University of Medical Sciences (A-12-892-38)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Radiation Therapy and Dosimetry
- Keywords
- curcumin, T2 MRI contrast agents, theranostics, pH-responsive drug delivery, reactive oxygen species generation, radiosensitization, triple-negative breast cancer, G2/M cell cycle arrest, apoptosis, Bcl-xL, cyclin D1, Bax
- MeSH terms
- Theranostic Nanomedicine, Metal-Organic Frameworks, Animals, Antineoplastic Agents, Cell Survival, Contrast Media, Curcumin, Drug Screening Assays, Antitumor, Female, Humans, Hydrogen-Ion Concentration, Imidazoles, Magnetic Resonance Imaging, Particle Size, Radiation-Sensitizing Agents, Apoptosis, Reactive Oxygen Species, Cell Line, Tumor, Cell Proliferation, Mice, Triple Negative Breast Neoplasms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review