The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Non‐coding RNAs in imprinted gene clusters
Open accessAbstract
Imprinted ncRNA (non‐coding RNA) genes represent a family of untranslated transcripts that are mono‐allelically expressed in a parent‐of‐origin manner (their expression is restricted to either the maternal or the paternal allele). Although the expression of a few long imprinted ncRNAs act as cis‐acting silencers in the epigenetic regulation of chromatin at imprinted gene clusters, many of them fall into the growing class of small regulatory RNAs, namely C/D small nucleolar RNAs, microRNAs and also likely piRNAs (Piwi‐interacting RNAs), which are known to act as antisense trans‐acting regulators of gene expression (for example, site‐specific RNA modifications and RNA‐mediated gene silencing). Although their biological functions remain elusive, recent studies have pointed to their functional importance in development, in brain plasticity and also perhaps in some pathological situations, such as cancers or Prader—Willi syndrome. In this review, we summarize our current understanding of the molecular and biological roles of these ncRNAs, both in terms of their contribution to genomic imprinting control, as well as in terms of cellular RNA targets they might interact with.
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Cites
A brain-specific microRNA regulates dendritic spine development
Schratt, G. M., Tuebing, F., Nigh, E. A., Kane, C. G., Sabatini, M. E., Kiebler, M., & Greenberg, M. E. (2006) · Nature · doi:10.1038/nature04367 · Cited by 1,786
A germline-specific class of small RNAs binds mammalian Piwi proteins
Girard, A., Sachidanandam, R., Hannon, G. J., & Carmell, M. A. (2006) · Nature · doi:10.1038/nature04917 · Cited by 1,762
Regulation of serotonin-2C receptor G-protein coupling by RNA editing
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“By altering the genetic information encoded within the edited 5-HT2C receptor mRNA, A-to-I RNA editing at the C-site, as well as the E-site, plays a key role in regulating serotonergic signal transduction (Burns et al., 1997; Gurevich et al., 2002).”
BackgroundGenome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
Broad Institute Genome Sequencing Platform, Mikkelsen, T. S., Broad Institute Whole Genome Assembly Team, Wakefield, M. J., Aken, B., Amemiya, C. T., Chang, J. L., Duke, S., Garber, M., Gentles, A. J., et al. (2007) · Nature · doi:10.1038/nature05805 · Cited by 711
AAV vector integration sites in mouse hepatocellular carcinoma
Donsante, A., Miller, D. G., Li, Y., Vogler, C., Brunt, E. M., Russell, D. W., & Sands, M. S. (2007) · Science · doi:10.1126/science.1142658 · Cited by 662
Genome Organization, Function, and Imprinting in Prader-Willi and Angelman Syndromes
Nicholls, R. D., & Knepper, J. L. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.153 · Cited by 625
Murrell, A., Heeson, S., & Reik, W. (2004) · Nature Genetics · doi:10.1038/ng1402 · Cited by 556 · cited 1×
“Imprinted long ncRNAs as simple miRNA precursors H19 ncRNA is part of a particularly well-studied imprinted gene cluster: the Igf2–H19 locus (for further discussion, see Murrell et al., 2004) (Figure 3).”
BackgroundM6P/IGF2R Imprinting Evolution in Mammals
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Cited by
Long noncoding RNAs: functional surprises from the RNA world
Wilusz, J. E., Sunwoo, H., & Spector, D. L. (2009) · Genes & Development · doi:10.1101/gad.1800909 · Cited by 2,294
Xie, W., Barr, C. L., Kim, A., Yue, F., Lee, A. Y., Eubanks, J., Dempster, E. L., & Ren, B. (2012) · Cell · doi:10.1016/j.cell.2011.12.035 · Cited by 543
Long Noncoding RNAs with snoRNA Ends
Yin, Q.-F., Yang, L., Zhang, Y., Xiang, J.-F., Wu, Y.-W., Carmichael, G. G., & Chen, L.-L. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.07.033 · Cited by 444
Nelissen, E. C. M., van Montfoort, A. P. A., Dumoulin, J. C. M., & Evers, J. L. H. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmq052 · Cited by 384
The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta
Noguer-Dance, M., Abu-Amero, S., Al-Khtib, M., Lefevre, A., Coullin, P., Moore, G. E., & Cavaille, J. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq272 · Cited by 323
Metadata
- Authors
- Royo, H., & Cavaillé, J.
- Venue
- Biology of the Cell
- Publisher
- Wiley
- Published
- 2008-03
- Volume
- 100
- Issue
- 3
- Pages
- 149-166
- ISSN
- 0248-4900 (ISSN-L)
- 1768-322X
- OpenAlex
- W1997714925
- Cited by
- 191
- References
- 9
- FWCI
- 15.82
- Type
- journal article
- Language
- en
- Open access
- bronze
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