The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Ascorbic acid, metal ions and the superoxide radical
Open accessAbstract
1. No evidence could be found for production of the superoxide radical, O2-, during autoxidation of ascorbic acid at alkaline pH values. Indeed, ascorbate may be important in protection against O2- genat-d in vivo. 2. Oxidation of ascorbate at pH 10.2 was stimulated by metal ions. Stimulation by Fe2+ was abolished by superoxide dismutase, probably because of generation of O2- during reduction of O2 by Fe2+, followed by reaction of O2- with ascorbate. EDTA changed the mechanism of Fe2+-stimulated ascorbate oxidation. 3. Stimulation of ascorbate oxidation by Cu2+ was also decreased by superoxide dismutase, but this appears to be an artifact, since apoenzyme or bovine serum albumin showed similar effects.
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Citations
Cites
Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels
Beauchamp, C., & Fridovich, I. (1971) · Analytical Biochemistry · doi:10.1016/0003-2697(71)90370-8 · Cited by 12,892
Cited by
[1] Role of free radicals and catalytic metal ions in human disease: An overview
Halliwell, B., & Gutteridge, J. M. C. (1990) · Methods in Enzymology · doi:10.1016/0076-6879(90)86093-b · Cited by 4,994
Self-citationReactive oxygen species homeostasis and signalling during drought and salinity stresses
MILLER, G., SUZUKI, N., CIFTCI‐YILMAZ, S., & MITTLER, R. (2010) · Plant, Cell & Environment · doi:10.1111/j.1365-3040.2009.02041.x · Cited by 3,945
The importance of free radicals and catalytic metal ions in human diseases.
Halliwell, B., & Gutteridge, J. M. C. (1985) · Molecular Aspects of Medicine · doi:10.1016/0098-2997(85)90001-9 · Cited by 941
Self-citationHow to Characterize a Biological Antioxidant
Halliwell, B. (1990) · Free Radical Research Communications · doi:10.3109/10715769009148569 · Cited by 927
Self-citationCatalytic Metals, Ascorbate and Free Radicals: Combinations to Avoid
Buettner, G. R., & Jurkiewicz, B. A. (1996) · Radiation Research · doi:10.2307/3579271 · Cited by 887
Metadata
- Authors
- Halliwell, B., & Foyer, C. H.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1976-06-01
- Volume
- 155
- Issue
- 3
- Pages
- 697-700
- ISSN
- 0264-6021 (ISSN-L)
- OpenAlex
- W1876152168
- Cited by
- 195
- References
- 1
- FWCI
- 6.74
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Halliwell, B., & Foyer, C. H. (1976). Ascorbic acid, metal ions and the superoxide radical. Biochemical Journal. https://doi.org/10.1042/bj1550697
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
