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Mitochondrial General Control of Amino Acid Synthesis 5 Like 1 Regulates Glutaminolysis, Mammalian Target of Rapamycin Complex 1 Activity, and Murine Liver Regeneration

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Significance of Mitochondrial Protein Post-translational Modifications in Pathophysiology of Brain Injury

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Acetylation contributes to hypertrophy-caused maturational delay of cardiac energy metabolism

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Glyoxalase 2: Towards a Broader View of the Second Player of the Glyoxalase System

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GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes

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The emerging roles of GCN5L1 in mitochondrial and vacuolar organelle biology

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Enzymatic and nonenzymatic protein acetylations control glycolysis process in liver diseases

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Hat1-Dependent Lysine Acetylation Targets Diverse Cellular Functions

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Post-translational Acetylation Control of Cardiac Energy Metabolism

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BLOC1S1/GCN5L1/BORCS1 is a critical mediator for the initiation of autolysosomal tubulation

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A “Weird” Mitochondrial Fatty Acid Oxidation as a Metabolic “Secret” of Cancer

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Diurnal regulation of the function of the rat brain glutamate dehydrogenase by acetylation and its dependence on thiamine administration

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Catalysis by protein acetyltransferase Gcn5

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Acetyl-l-carnitine increases mitochondrial protein acetylation in the aged rat heart

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Molecular Mechanisms of Leucine Zipper EF-Hand Containing Transmembrane Protein-1 Function in Health and Disease

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The role of lysine acetylation in metabolic sensing and proteostasis

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Fibroblast-to-cardiomyocyte lactate shuttle modulates hypertensive cardiac remodelling

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Acetylation in Mitochondria Dynamics and Neurodegeneration

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Mitochondrial Acetylation and Genetic Models of Parkinson's Disease

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KATapulting toward Pluripotency and Cancer

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A comprehensive analysis of the lysine acetylome reveals diverse functions of acetylated proteins during de-etiolation in Zea mays

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Proteomic Profiling of Lysine Acetylation Indicates Mitochondrial Dysfunction in the Hippocampus of Gut Microbiota-Absent Mice

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Mitochondrial MOF regulates energy metabolism in heart failure via ATP5B hyperacetylation

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GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking

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Pre-silencing of genes involved in the electron transport chain (ETC) pathway is associated with responsiveness to abatacept in rheumatoid arthritis

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Learning from Fifteen Years of Genome-Wide Association Studies in Age-Related Macular Degeneration

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Deacetylation mimetic mutation of mitochondrial SOD2 attenuates ANG II-induced hypertension by protecting against oxidative stress and inflammation

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Drp1 acetylation mediated by CDK5-AMPK-GCN5L1 axis promotes cerebral ischemic injury via facilitating mitochondrial fission

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Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome

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GCN5L1-mediated TFAM acetylation at K76 participates in mitochondrial biogenesis in acute kidney injury

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An acetylation rheostat for the control of muscle energy homeostasis

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SAGA complex and Gcn5 are necessary for respiration in budding yeast

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Methylene blue decreases mitochondrial lysine acetylation in the diabetic heart

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Lysine Acetyltransferases (KATs) in Disguise: Diseases Implications

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Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation

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Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle

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An integrated perspective and functional impact of the mitochondrial acetylome

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Chemical acetylation of mitochondrial transcription factor A occurs on specific lysine residues and affects its ability to change global DNA topology

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Gcn5 histone acetyltransferase is present in the mitoplasts

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SIRT1 deacetylates mitochondrial trifunctional enzyme α subunit to inhibit ubiquitylation and decrease insulin resistance

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SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2

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A new role for α‐ketoglutarate dehydrogenase complex: regulating metabolism through post‐translational modification of other enzymes

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Mitochondria and Epigenetic Regulation: Bidirectional Crosstalk and Emerging Mitochondria-Targeted Degron Tools

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The endo-lysosomal regulatory protein BLOC1S1 modulates hepatic lysosomal content and lysosomal lipolysis

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Brain ethanol metabolism and mitochondria.

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Sirtuin activation as a therapeutic approach against inborn errors of metabolism

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A high-fat diet increases hepatic mitochondrial turnover through restricted acetylation in a NAFLD mouse model

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Acetyl‐ed question in mitochondrial biology?

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Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function

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Ubiquitin protease Ubp8 is necessary for S. cerevisiae respiration

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Loss of GCN5L1 in cardiac cells limits mitochondrial respiratory capacity under hyperglycemic conditions

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Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart

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Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein

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Perturbed Brain Glucose Metabolism Caused by Absent SIRT3 Activity

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Dietary Restriction Increases Protein Acetylation in the Livers of Aged Rats

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Role of yUbp8 in Mitochondria and Hypoxia Entangles the Finding of Human Ortholog Usp22 in the Glioblastoma Pseudo-Palisade Microlayer

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The role of protein acetylation in regulating mitochondrial fusion and fission

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Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function

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GPER-dependent estrogen signaling increases cardiac GCN5L1 expression

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Mitochondrial GCN5L1 regulates cytosolic redox state and hepatic gluconeogenesis via glycerol phosphate shuttle GPD2

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Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice

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G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction

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Protein Lysine Acetylation: Grease or Sand in the Gears of β-Cell Mitochondria?

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An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation

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Harnessing mitochondrial biogenesis to combat acute kidney injury: Current insights and futuredirections

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Reduction in Acetylation of Superoxide Dismutase 2 in Skeletal Muscle Improves Exercise Capacity in Mice With Heart Failure

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The role of acetylation in obesity-induced cardiac metabolic alterations

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Mitochondrial GCN5L1 coordinates with YME1L and MICOS to remodel mitochondrial cristae in white adipocytes and modulate obesity

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Inhalation of Ultrafine Carbon Black-Induced Mitochondrial Dysfunction in Mouse Heart Through Changes in Acetylation

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GCN5L1 Aggravates Postherpetic Neuralgia Through Regulating Microglial Mitochondrial Fission–Fusion Homeostasis

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Mitochondrial retrograde signal through GCN5L1 transition–mediated PPARγ stabilization promotes MASLD development

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Validation of GCN5L1/BLOC1S1/BLOS1 antibodies using knockout cells and tissue

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Histone Acetyltransferases: Targets and Inhibitors

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Autophagy Regulates Control of Intracellular Energy Stores

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Role of Lysine Acetylation in the Control of Cardiac Energy Metabolism

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Integrated Regulation of Cardiac Fatty Acid and Glucose Oxidation

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Maturation of Cardiac Energy Metabolism in the Normal and Hypertrophied Newborn Heart

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The Effect of Endurance Training on the Expression of PRDX6 and KAT2B Genes in Hippocampus of Beta Amyloid-Induced Rat Model of Alzheimer's Disease: An Experimental Study

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GCN5L1 promotes diastolic dysfunction by inhibiting cardiac pyruvate oxidationPreprint

Thapa, D., Bugga, P., Mushala, B. A. S., Manning, J. R., Stoner, M. W., McMahon, B., Zeng, X., Cantrell, P. S., Yates, N. A., Xie, B., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.07.459319

GCN5L1 Functions as a Mitochondrial Acetyltransferase that Regulates Mitophagy

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Deacetylation by SIRT3 Relieves Inhibition of Mitochondrial Protein Function

Chhoy, P., Anderson, K. A., Hershberger, K. A., Huynh, F. K., Martin, A. S., McDonnell, E., Peterson, B. S., Starzenski, L. A., Backos, D. S., Fritz, K. S., et al. (2016) · Springer eBooks · doi:10.1007/978-94-024-0962-8_5 · Cited by 3

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