Cognitive behavioural therapy on improving the depression symptoms in patients with diabetes: a meta-analysis of randomized control trials
Open accessAbstract
This meta-analysis was performed to evaluate the effect of cognitive behavioural therapy (CBT) in improving the depression symptoms of patients with diabetes. Literature search was conducted in PubMed and Embase up to October 2016 without the initial date. The pooled SMD (standard mean difference) and its 95% confidence interval (CI) were calculated by Revman 5.3. Subgroup analyses were performed by type of diabetes and evaluation criteria of depression. A total of five randomized control trials involving 834 patients with diabetes mellitus (including 417 patients in CBT group and 417 patients in control group) were included in this meta-analysis. The pooled estimates indicated significant improvement of depression by CBT compared with routine approaches in overall outcomes (SMD =–0.33, 95% CI =–0.46 to –0.21, P<0.00001), post-intervention outcomes (SMD =–0.43, 95% CI =–0.73 to –0.12, P=0.006) and outcomes after 12 months intervention (SMD =–0.38, 95% CI = –0.54 to –0.23, P<0.0001). Subgroup analyses showed that the results were not influenced by the type of diabetes. However, the effect of CBT on improving the depression symptoms disappeared when only using CES-D (Centre for Epidemiological Studies scale for Depression) to evaluate depression.
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CBT-based intervention has a significant effect on reducing depression and anxiety symptoms in DM patients.
“Similar to previous research 25,26 , our meta-analysis found a significant effect of CBTbased intervention on reducing depression and anxiety symptoms in DM patients, further validating the effectiveness of CBT for emotion intervention.”
From The efficacy of cognitive behavioral therapy-based intervention on patients with diabetes: a meta-analysis (2022) · cites this paper as [25]
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- Authors
- Wang, Z.-D., Xia, Y.-F., Zhao, Y., & Chen, L.-M.
- Affiliations
- Key Laboratory of Hormones and Development (Ministry of Health), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin 300070, China
- Tianjin Medical University (CN)
- Corresponding author
- Zhao, Yue
- ORCID
- Zhao, Yue
- Venue
- Bioscience Reports
- Publisher
- Portland Press Ltd.
- Published
- 2017-04-10
- Volume
- 37
- Issue
- 2
- ISSN
- 0144-8463 (ISSN-L)
- 1573-4935
- PMC
- PMC5469329
- OpenAlex
- W2586639473
- Cited by
- 28
- References
- 38
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 7 · 2022: 6 · 2021: 5 · 2020: 4 · 2019: 3 · 2018: 1
- FWCI
- 0.32
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Bioscience Reports (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Natural Science Foundation of Tianjin City
- Tianjin Municipal Bureau of Public Health
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- cognitive behavioral therapy, depression, diabetes mellitus, diabetes-related depression, depression symptom improvement, type of diabetes, psychological intervention
- MeSH terms
- Depression, Diabetes Mellitus, Humans, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Outcome Assessment, Health Care
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