Regulation of mammalian acetyl-CoA carboxylase

Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase

Hardie, D. G., & Pan, D. A. (2002) · Biochemical Society Transactions · doi:10.1042/bst0301064 · Cited by 561 · see citing works

The multifaceted contributions of mitochondria to cellular metabolism

Spinelli, J. B., & Haigis, M. C. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0124-1 · Cited by 1,935 · see citing works

AMPK in Health and Disease

Steinberg, G. R., & Kemp, B. E. (2009) · Physiological Reviews · doi:10.1152/physrev.00011.2008 · Cited by 1,633 · see citing works

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

Inoki, K., Kim, J., & Guan, K. (2011) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010611-134537 · Cited by 800 · see citing works

Gene networks driving bovine milk fat synthesis during the lactation cycle

Bionaz, M., & Loor, J. J. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-366 · Cited by 786 · see citing works

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

Musso, G., Gambino, R. J., & Cassader, M. (2008) · Progress in Lipid Research · doi:10.1016/j.plipres.2008.08.001 · Cited by 678 · see citing works

De novo lipogenesis in the liver in health and disease: more than just a shunting yard for glucose

Sanders, F., & Griffin, J. L. (2015) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12178 · Cited by 543 · see citing works

Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials

Dambrova, M., Makrecka‐Kuka, M., Kuka, J., Vilšķe̅rsts, R., Nordberg, D. O. T., Attwood, M. M., Smesny, S., Şen, Z. D., Guo, A. C., Oler, E., et al. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000408 · Cited by 528 · see citing works

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2

Savage, D. B. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27300 · Cited by 447 · see citing works

Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis

Koo, S. (2013) · Clinical and Molecular Hepatology · doi:10.3350/cmh.2013.19.3.210 · Cited by 421 · see citing works

Targeting fatty acid and carbohydrate oxidation — A novel therapeutic intervention in the ischemic and failing heart

Jaswal, J. S., Keung, W., Wang, W., Ussher, J. R., & Lopaschuk, G. D. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2011.01.015 · Cited by 396 · see citing works

Integrating canonical and metabolic signalling programmes in the regulation of T cell responses

Pollizzi, K. N., & Powell, J. D. (2014) · Nature reviews. Immunology · doi:10.1038/nri3701 · Cited by 379 · see citing works

Lipid metabolic enzymes: emerging drug targets for the treatment of obesity

Shi, Y., & Burn, P. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1469 · Cited by 333 · see citing works

Thr2446 Is a Novel Mammalian Target of Rapamycin (mTOR) Phosphorylation Site Regulated by Nutrient Status

Cheng, S., Fryer, L. G. D., Carling, D., & Shepherd, P. R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.c300534200 · Cited by 328 · see citing works

Glycerolipid Metabolism and Signaling in Health and Disease

Prentki, M., & Madiraju, S. R. M. (2008) · Endocrine Reviews · doi:10.1210/er.2008-0007 · Cited by 322 · see citing works

Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity

Choi, C. S., Savage, D. B., Abu-Elheiga, L., Liu, Z.-X., Kim, S., Kulkarni, A., Distefano, A., Hwang, Y.-J., Reznick, R. M., Codella, R., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706794104 · Cited by 325 · see citing works

AMPK-Mediated Regulation of Lipid Metabolism by Phosphorylation

Wang, Q., Liu, S., Zhai, A., Zhang, B., & Tian, G. (2018) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b17-00724 · Cited by 315 · see citing works

Dietary l-arginine supplementation increases muscle gain and reduces body fat mass in growing-finishing pigs

Tan, B., Yin, Y., Liu, Z., Xin-guo, L., Xu, H.-J., Kong, X., Huang, R., Tang, W., Shinzato, I., Smith, S. B., et al. (2008) · Amino Acids · doi:10.1007/s00726-008-0148-0 · Cited by 309 · see citing works

Malonyl-CoA, a Key Signaling Molecule in Mammalian Cells

Saggerson, D. (2008) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.28.061807.155434 · Cited by 301 · see citing works

Targeting protein modifications in metabolic diseases: molecular mechanisms and targeted therapies

Wu, X., Xu, M., Geng, M., Chen, S., Little, P. J., Xu, S., & Weng, J. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01439-y · Cited by 290 · see citing works

AMPK signaling and its targeting in cancer progression and treatment

Hsu, C.-C., Peng, D., Cai, Z., & Lin, H. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2021.04.006 · Cited by 257 · see citing works

Acetyl-CoA Carboxylases and Diseases

Wang, Y., Yu, W., Li, S., Guo, D., He, J., & Wang, Y. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.836058 · Cited by 225 · see citing works

Dietary l-arginine supplementation differentially regulates expression of lipid-metabolic genes in porcine adipose tissue and skeletal muscle

Tan, B., Yin, Y., Liu, Z., Tang, W., Xu, H.-J., Kong, X., Xin-guo, L., Yao, K., WanTing, G., Smith, S. B., et al. (2010) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.03.012 · Cited by 191 · see citing works

Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver

Ashino, N. G., Saito, K. N., Souza, F. D., Nakutz, F. S., Roman, E. A., Velloso, L. A., Torsoni, A. S., & Torsoni, M. A. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.12.011 · Cited by 187 · see citing works

Direct metabolic regulation in skeletal muscle and fat tissue by leptin: implications for glucose and fatty acids homeostasis

Ceddia, R. B. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0803025 · Cited by 177 · see citing works

Histological evaluation of AMPK signalling in primary breast cancer

Hadad, S. M., Baker, L., Quinlan, P., Robertson, K. E., Bray, S. E., Thomson, G., Kellock, D., Jordan, L. B., Purdie, C. A., Hardie, D. G., et al. (2009) · BMC Cancer · doi:10.1186/1471-2407-9-307 · Cited by 173 · see citing works

Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress

Gómez‐Zorita, S., Fernández‐Quintela, A., Macarulla, M. T., Aguirre, L., Hijona, E., Bujanda, L., Milagro, F. I., Martínez, J. A., & Portillo, M. P. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511002753 · Cited by 163 · see citing works

Functional and structural properties of mammalian acyl-coenzyme A thioesterases

Kirkby, B., Roman, N., Kobe, B., Kellie, S., & Forwood, J. K. (2010) · Progress in Lipid Research · doi:10.1016/j.plipres.2010.04.001 · Cited by 163 · see citing works

Metabolic regulation of citrate and iron by aconitases: role of iron–sulfur cluster biogenesis

Tong, W.-H., & Rouault, T. A. (2007) · BioMetals · doi:10.1007/s10534-006-9047-6 · Cited by 158 · see citing works

Dependence of Arbuscular-Mycorrhizal Fungi on Their Plant Host for Palmitic Acid Synthesis

Trépanier, M., Bécard, G., Moutoglis, P., WILLEMOT, C., Gagné, S., Avis, T. J., & Rioux, J.-A. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.9.5341-5347.2005 · Cited by 157 · see citing works

AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats

Assifi, M. M., Suchánková, G., Constant, S., Prentki, M., Saha, A. K., & Ruderman, N. B. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00144.2005 · Cited by 155 · see citing works

Inactivation of the AMPK-GATA3-ECHS1 Pathway induces Fatty Acid Synthesis that Promotes Clear Cell Renal Cell Carcinoma Growth.

Qu, Y., Zhao, R., Zhang, H.-L., Zhou, Q., Xu, F., Zhang, X., Xu, W.-H., Shao, N., Zhou, S.-X., Dai, B., et al. (2019) · Cancer Research · doi:10.1158/0008-5472.can-19-1023 · Cited by 118 · see citing works

Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats

Shen, L., Xiong, Y., Wang, D. Q. ‐., Howles, P. N., Basford, J. E., Wang, J., Xiong, Y., Hui, D. Y., Woods, S. C., & Liu, M. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m035907 · Cited by 126 · see citing works

Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition

Harwood, H. J., Jr. (2005) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.9.2.267 · Cited by 127 · see citing works

Adipose tissue development and lipid metabolism in the human fetus: The 2020 perspective focusing on maternal diabetes and obesity

Desoyé, G., & Herrera, E. (2020) · Progress in Lipid Research · doi:10.1016/j.plipres.2020.101082 · Cited by 126 · see citing works

Human Cytomegalovirus Induces the Activity and Expression of Acetyl-Coenzyme A Carboxylase, a Fatty Acid Biosynthetic Enzyme Whose Inhibition Attenuates Viral Replication

Spencer, C. M., Schafer, X., Moorman, N. J., & Munger, J. C. (2011) · Journal of Virology · doi:10.1128/jvi.02630-10 · Cited by 124 · see citing works

Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells

Fediuc, S., Gaidhu, M. P., & Ceddia, R. B. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m500438-jlr200 · Cited by 121 · see citing works

Changes in white adipose tissue metabolism induced by resveratrol in rats

Alberdi, G., Rodríguez, V. M., Miranda, J., Macarulla, M. T., Arias, N., Andrés‐Lacueva, C., & Portillo, M. P. (2011) · Nutrition & Metabolism · doi:10.1186/1743-7075-8-29 · Cited by 118 · see citing works

Ameliorative potential of gingerol: Promising modulation of inflammatory factors and lipid marker enzymes expressions in HFD induced obesity in rats

Naidu, P. B., Uddandrao, V. V. S., Naik, R. R., Suresh, P., Meriga, B., Begum, M. S., Pandiyan, R., & Saravanan, G. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.10.007 · Cited by 116 · see citing works

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells

Jones, J. E. C., Esler, W. P., Patel, R. S., Lanba, A., Vera, N. B., Pfefferkorn, J. A., & Vernochet, C. (2017) · PLoS ONE · doi:10.1371/journal.pone.0169566 · Cited by 113 · see citing works

Regulation of fatty acid uptake and metabolism in L6 skeletal muscle cells by resistin

Palanivel, R., & Sweeney, G. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.08.011 · Cited by 111 · see citing works

Intramyocellular lipid accumulation is associated with permanent relocation ex vivo and in vitro of fatty acid translocase (FAT)/CD36 in obese patients

Aguer, C., Mercier, J. G., Man, C. Y. W., Metz, L., Bordenave, S., Lambert, K., Jean, E., Lantier, L., Bounoua, L., Brun, J. ‐., et al. (2010) · Diabetologia · doi:10.1007/s00125-010-1708-x · Cited by 110 · see citing works

STK11/LKB1 Modulation of the Immune Response in Lung Cancer: From Biology to Therapeutic Impact

Tostivint, E. P., Lugat, A., Fontenau, J.-F., Denis, M. G., & Bennouna, J. (2021) · Cells · doi:10.3390/cells10113129 · Cited by 103 · see citing works

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-induced AMP-activated Protein Kinase Phosphorylation Inhibits Basal and Insulin-stimulated Glucose Uptake, Lipid Synthesis, and Fatty Acid Oxidation in Isolated Rat Adipocytes

Gaidhu, M. P., Fediuc, S., & Ceddia, R. B. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602992200 · Cited by 108 · see citing works

SIRT1/Adenosine Monophosphate-Activated Protein Kinase α Signaling Enhances Macrophage Polarization to an Anti-inflammatory Phenotype in Rheumatoid Arthritis

Park, S. Y., Lee, S. W., Lee, S. Y., Hong, K. W., Bae, S. S., Kim, K., & Kim, C. D. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01135 · Cited by 106 · see citing works

Hepatic lipid metabolic pathways modified by resveratrol in rats fed an obesogenic diet

Alberdi, G., Rodríguez, V. M., Macarulla, M. T., Miranda, J., Churruca, I., & Portillo, M. P. (2012) · Nutrition · doi:10.1016/j.nut.2012.09.011 · Cited by 106 · see citing works

The role of AMP-activated protein kinase in regulating white adipose tissue metabolism

Ceddia, R. B. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.06.014 · Cited by 105 · see citing works

Silencing of FABP 1 ameliorates hepatic steatosis, inflammation, and oxidative stress in mice with nonalcoholic fatty liver disease

Mukai, T., Egawa, M., Takeuchi, T., Yamashita, H., & Kusudo, T. (2017) · FEBS Open Bio · doi:10.1002/2211-5463.12240 · Cited by 105 · see citing works

High Fat Activates O-GlcNAcylation and Affects AMPK/ACC Pathway to Regulate Lipid Metabolism

Pang, Y., Xu, X., Xiang, X., Li, Y., Zhao, Z., Li, J., Gao, S., Liu, Q., Mai, K., & Ai, Q. (2021) · Nutrients · doi:10.3390/nu13061740 · Cited by 108 · see citing works

GLP-1 analog liraglutide protects against cardiac steatosis, oxidative stress and apoptosis in streptozotocin-induced diabetic rats

Inoue, T., Inoguchi, T., Sonoda, N., Hendarto, H., Makimura, H., Sasaki, S., Yokomizo, H., Fujimura, Y., Miura, D., & Takayanagi, R. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.03.026 · Cited by 104 · see citing works

Regulatory Efficacy of the Polyunsaturated Fatty Acids from Microalgae Spirulina platensis on Lipid Metabolism and Gut Microbiota in High-Fat Diet Rats

Li, T.-T., Liu, Y.-Y., Wan, X.-Z., Huang, Z.-R., Liu, B., & Zhao, C. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19103075 · Cited by 103 · see citing works

Regulatory roles for L-arginine in reducing white adipose tissue

Tan, B. (2012) · Frontiers in bioscience · doi:10.2741/4047 · Cited by 103 · see citing works

β-Adrenoceptors, but not α-adrenoceptors, stimulate AMP-activated protein kinase in brown adipocytes independently of uncoupling protein-1

Hutchinson, D. S., Chernogubova, E., Dallner, O. S., Cannon, B., & Bengtsson, T. (2005) · Diabetologia · doi:10.1007/s00125-005-1936-7 · Cited by 99 · see citing works

Activation of AMP-activated Protein Kinase by Vascular Endothelial Growth Factor Mediates Endothelial Angiogenesis Independently of Nitric-oxide Synthase

Stahmann, N., Woods, A., Spengler, K., Heslegrave, A., Bauer, R., Krause, S., Viollet, B., Carling, D., & Heller, R. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.108688 · Cited by 98 · see citing works

Mitigating efficacy of piperine in the physiological derangements of high fat diet induced obesity in Sprague Dawley rats

Parim, B., Nemani, H., Meriga, B., Mehar, S. K., Potana, S., & Ramgopalrao, S. (2014) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2014.07.008 · Cited by 100 · see citing works

Identification of Dicarboxylate Carrier Slc25a10 as Malate Transporter in de Novo Fatty Acid Synthesis

Mizuarai, S., Miki, S., Araki, H., Takahashi, K., & Kotani, H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503152200 · Cited by 96 · see citing works

Role of malonyl-CoA in heart disease and the hypothalamic control of obesity

Folmes, C. D. L., & LOPASCHUK, G. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.10.008 · Cited by 95 · see citing works

Simvastatin-Induced Apoptosis in Osteosarcoma Cells: A Key Role of RhoA-AMPK/p38 MAPK Signaling in Antitumor Activity

Kamel, W., Sugihara, E., Nobusue, H., Yamaguchi‐Iwai, S., Onishi, N., Maki, K., Fukuchi, Y., Matsuo, K., Muto, A., Saya, H., et al. (2016) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-16-0499 · Cited by 94 · see citing works

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

Hulea, L., Gravel, S., Morita, M., Cargnello, M., Uchenunu, O., Im, Y. K., Lehuédé, C., Ma, E. H., Leibovitch, M., McLaughlan, S., et al. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.09.001 · Cited by 87 · see citing works

Salidroside stimulated glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase

Li, H., Ge, Y., Zheng, X., & Zhang, L. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.04.036 · Cited by 89 · see citing works

The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting

Hall, D. T., Griss, T., Ma, J. F., Sanchez, B. J., Sadek, J., Tremblay, A. M. K., Mubaid, S., Omer, A., Ford, R. J., Bedard, N., et al. (2018) · EMBO Molecular Medicine · doi:10.15252/emmm.201708307 · Cited by 88 · see citing works

Obestatin as a regulator of adipocyte metabolism and adipogenesis

Gurriarán‐Rodríguez, U., Al–Massadi, O., Roca-Rivada, A., Crujeiras, A. B., Gallego, R., Pardo, M., Seoane, L. M., Pazos, Y., Casanueva, F. F., & Camiña, J. P. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2010.01192.x · Cited by 87 · see citing works

AMPK‐dependent hormonal regulation of whole‐body energy metabolism

Dzamko, N. L., & Steinberg, G. R. (2009) · Acta Physiologica · doi:10.1111/j.1748-1716.2009.01969.x · Cited by 88 · see citing works

The Role of Mitochondrial Fat Oxidation in Cancer Cell Proliferation and Survival

Oliveira, M., & Liesa, M. (2020) · Cells · doi:10.3390/cells9122600 · Cited by 87 · see citing works

Fermented mixed feed alters growth performance, carcass traits, meat quality and muscle fatty acid and amino acid profiles in finishing pigs

Liu, S., Du, M., Tu, Y., You, W., Chen, W., Liu, G., Li, J., Wang, Y., Lu, Z., Wang, T., et al. (2022) · Animal nutrition · doi:10.1016/j.aninu.2022.09.003 · Cited by 83 · see citing works

Role of the Electrophilic Lipid Peroxidation Product 4-Hydroxynonenal in the Development and Maintenance of Obesity in Mice

Singh, S. P., Niemczyk, M., Saini, D., Awasthi, S., Zimniak, L., & Zimniak, P. (2008) · Biochemistry · doi:10.1021/bi702124u · Cited by 80 · see citing works

AMP-Activated Protein Kinase Activation by Adrenoceptors in L6 Skeletal Muscle Cells

Hutchinson, D. S., & Bengtsson, T. (2006) · Diabetes · doi:10.2337/diabetes.55.03.06.db05-0901 · Cited by 79 · see citing works

AMP-activated protein kinase — the fat controller of the energy railroadThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.

Steinberg, G. R., Macaulay, S. L., Febbraio, M. A., & Kemp, B. E. (2006) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y06-005 · Cited by 76 · see citing works

The Mitochondrial Citrate Carrier SLC25A1/CIC and the Fundamental Role of Citrate in Cancer, Inflammation and Beyond

Mosaoa, R., Kasprzyk-Pawelec, A., Fernandez, H. R., & Avantaggiati, M. L. (2021) · Biomolecules · doi:10.3390/biom11020141 · Cited by 76 · see citing works

Effects of dietary glutamate supplementation on flesh quality, antioxidant defense and gene expression related to lipid metabolism and myogenic regulation in Jian carp (Cyprinus carpio var. Jian)

Zhao, Y., Li, J.-Y., Yin, L. W., Feng, L., Liu, Y., Jiang, W., Wu, P., Zhao, J., Chen, D., Zhou, X., et al. (2018) · Aquaculture · doi:10.1016/j.aquaculture.2018.12.050 · Cited by 69 · see citing works

Plants used to treat diabetes in Sri Lankan Siddha Medicine – An ethnopharmacological review of historical and modern sources

SATHASİVAMPİLLAİ, S. V., Rajamanoharan, P. R. S., Munday, M. R., & Heinrich, M. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.07.053 · Cited by 68 · see citing works

NOX4 Pathway as a Source of Selective Insulin Resistance and Responsiveness

Wu, X., & Williams, K. J. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.111.244525 · Cited by 65 · see citing works

Changes in the biochemical composition of fat body stores during adult development of female crickets, Gryllus bimaculatus

Lorenz, M. W., & Anand, A. N. (2004) · Archives of Insect Biochemistry and Physiology · doi:10.1002/arch.20002 · Cited by 67 · see citing works

Metformin activation of AMPK suppresses AGE-induced inflammatory response in hNSCs

Chung, M.-M., Nicol, C. J., Cheng, Y.-C., Lin, K.-H., Chen, Y.-L., Pei, D., Lin, C.-H., Shih, Y.-N., Yen, C.-H., Chen, S.-J., et al. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.01.017 · Cited by 66 · see citing works

Different dietary starch sources alter the carcass traits, meat quality, and the profile of muscle amino acid and fatty acid in finishing pigs

Yu, M., Li, Z., Rong, T. Z., Wang, G., Liu, Z., Chen, W., Li, J., Li, J., & Ma, X. (2020) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-020-00484-9 · Cited by 66 · see citing works

Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS

Westergaard, N., Waagepetersen, H., Belhage, B., & Schousboe, A. (2017) · Neurochemical Research · doi:10.1007/s11064-016-2159-7 · Cited by 58 · see citing works

Evaluation of milk somatic cells as a source of mRNA for study of lipogenesis in the mammary gland of lactating beef cows supplemented with dietary high-linoleate safflower seeds1

Murrieta, C. M., Hess, B. W., Scholljegerdes, E. J., Engle, T. E., HOSSNER, K. L., Moss, G. E., & Rule, D. C. (2006) · Journal of Animal Science · doi:10.2527/jas.2005-677 · Cited by 61 · see citing works

Mulberry extract inhibits oleic acid‐induced lipid accumulation via reduction of lipogenesis and promotion of hepatic lipid clearance

Ou, T., Hsu, M., Chan, K., Huang, C., Ho, H.-H., & Wang, C. (2011) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4489 · Cited by 61 · see citing works

Metabolism Characteristics of Th17 and Regulatory T Cells in Autoimmune Diseases

Qin, Y., Gao, C., & Luo, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.828191 · Cited by 62 · see citing works

Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model

Park, J.-Y., Kim, Y.-H., Im, J. A., & Lee, H. (2015) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-015-0709-1 · Cited by 57 · see citing works

Understanding Metabolic Regulation at a Systems Level: Metabolite Sensing, Mathematical Predictions, and Model Organisms

Watson, E. V., Yilmaz, L. S., & Walhout, A. J. M. (2015) · Annual Review of Genetics · doi:10.1146/annurev-genet-112414-055257 · Cited by 53 · see citing works

Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2

Kampe, K., Sieber, J., Orellana, J. M., Mundel, P. H., & Jehle, A. W. (2013) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00454.2013 · Cited by 54 · see citing works

(−)-Hydroxycitric acid reduced fat deposition via regulating lipid metabolism-related gene expression in broiler chickens

Han, J. D. J., Li, L., Wang, D., & Ma, H. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0208-5 · Cited by 55 · see citing works

Recent Development in Acetyl-CoA Carboxylase Inhibitors and their Potential as Novel Drugs

Wu, X., & Huang, T. (2020) · Future Medicinal Chemistry · doi:10.4155/fmc-2019-0312 · Cited by 55 · see citing works

Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding transcription factor 1 (Srebf1) and activation of peroxisome proliferator activated receptor alpha (Pparα)

Shi, L., Shi, L., Song, G., Zhang, H.-F., Hu, Z., Wang, C., & Zhang, D. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.06.013 · Cited by 54 · see citing works

The dynamic organization of fungal acetyl-CoA carboxylase

Hunkeler, M., Stuttfeld, E., Hagmann, A., Imseng, S., & Maier, T. (2016) · Nature Communications · doi:10.1038/ncomms11196 · Cited by 54 · see citing works

Chemical Genetics of Acetyl-CoA Carboxylases

Zu, X., Zhong, J., Luo, D., Tan, J., Zhang, Q., Wu, Y., Liu, J., Cao, R., Wen, G., & Cao, D. (2013) · Molecules · doi:10.3390/molecules18021704 · Cited by 53 · see citing works

Exercise training reduces the insulin‐sensitizing effect of a single bout of exercise in human skeletal muscle

Steenberg, D. E., Jørgensen, N. B., Birk, J. B., Sjøberg, K. A., Kiens, B., Richter, E. A., & Wojtaszewski, J. F. P. (2018) · The Journal of Physiology · doi:10.1113/jp276735 · Cited by 53 · see citing works

The molecular associations between the SnRK1 complex and carbon/nitrogen metabolism in plants

Han, C., Wang, H., Shi, W., & Bai, M. (2023) · New Crops · doi:10.1016/j.ncrops.2023.12.003 · Cited by 52 · see citing works

Dietary protein intake affects expression of genes for lipid metabolism in porcine skeletal muscle in a genotype-dependent manner

Liu, Y., Li, F., He, L., Tan, B., Deng, J., Kong, X., Li, Y., Geng, M., Yin, Y., & Wu, G. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114514004310 · Cited by 51 · see citing works

Effects of photoperiod on growth, lipid metabolism and oxidative stress of juvenile gibel carp (Carassius auratus)

Wei, H., Cai, W., Liu, H., Han, D. H., Zhu, X., Yang, Y., Jin, J., & Xie, S.-Q. (2019) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2019.111552 · Cited by 51 · see citing works

Fatty acid biosynthesis from glutamate and glutamine is specifically induced in neuronal cells under hypoxia

Brose, S. A., Marquardt, A. L., & Golovko, M. Y. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12617 · Cited by 50 · see citing works

Activation of AMP-Activated Protein Kinase by 3,3′-Diindolylmethane (DIM) Is Associated with Human Prostate Cancer Cell Death In Vitro and In Vivo

Chen, D., Banerjee, S., Cui, Q. C., Kong, D., Sarkar, F. H., & Dou, Q. P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047186 · Cited by 49 · see citing works

The regulation of AMPK signaling in a natural state of profound metabolic rate depression

Ramnanan, C. J., McMullen, D. C., Groom, A. G., & Storey, K. B. (2009) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-009-0246-7 · Cited by 48 · see citing works

Combination of citrus polymethoxyflavones, green tea polyphenols, and Lychee extracts suppresses obesity and hepatic steatosis in high‐fat diet induced obese mice

Pan, M., Yang, G., Li, S., Li, M., Tsai, M., Wu, J.-C., Badmaev, V., Ho, C., & Lai, C. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201601104 · Cited by 48 · see citing works

Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase β Subunit of Streptomyces coelicolor,

Arabolaza, A. L., Shillito, M. E., Lin, T., Diacovich, L., Melgar, M. M., Pham, H., Amick, D. L., Gramajo, H. C., & Tsai, S. (2010) · Biochemistry · doi:10.1021/bi1005305 · Cited by 48 · see citing works

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Regulate the Mitochondrial Metabolism via Transfer of miRNAs

Loussouarn, C., Pers, Y., Bony, C., Jørgensen, C., & Noël, D. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.623973 · Cited by 46 · see citing works

Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes

Xiao, X., Li, H., Qi, X., Wang, Y., Xu, C., Liu, G., Wen, G., & Liu, J. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.06.003 · Cited by 47 · see citing works

Expression and characterization of recombinant fungal acetyl-CoA carboxylase and isolation of a soraphen-binding domain

Weatherly, S. C., Volrath, S., & Elich, T. D. (2004) · Biochemical Journal · doi:10.1042/bj20031960 · Cited by 47 · see citing works

Complex Formation and Regulation of Escherichia coli Acetyl-CoA Carboxylase

Broussard, T. C., Price, A. E., Laborde, S. M., & Waldrop, G. L. (2013) · Biochemistry · doi:10.1021/bi4000707 · Cited by 46 · see citing works

Lipotoxic and inflammatory phenotypes in rats with uncontrolled metabolic syndrome and nephropathy

Dominguez, J. H., Wu, P., Packer, C. S., Temm, C. J., & Kelly, K. J. (2007) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00021.2007 · Cited by 46 · see citing works

REGULATION OF MAMMALIAN ACETYL-COENZYME A CARBOXYLASE

Kim, K.-H. (1997) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.17.1.77 · Cited by 394 · see citing works

Phosphorylation control of cardiac acetyl‐CoA carboxylase by cAMP‐dependent protein kinase and 5′‐AMP activated protein kinase

Dyck, J. R. B., Kudo, N., Barr, A., Davies, S. P., Hardie, D. G., & Lopaschuk, G. D. (1999) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1999.00371.x · Cited by 175 · see citing works

Regulation of acetyl-CoA carboxylase

Brownsey, R. W., Boone, A. N., Elliott, J. E., Kulpa, J. E., & Lee, W. M. (2006) · Biochemical Society Transactions · doi:10.1042/bst20060223 · Cited by 432 · see citing works

The regulation of Acetyl-CoA carboxylase—a potential target for the action of hypolipidemic agents

Munday, M. R., & Hemingway, C. J. (1999) · Advances in Enzyme Regulation · doi:10.1016/s0065-2571(98)00016-8 · Cited by 99 · see citing works

Amp-activated protein kinase and camp-dependent protein kinase from mammary gland of lactating rat.

Milic, M. R. (1995) · UCL Discovery (University College London)